A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action

Genesis

Volumn 32, Issue 1, 2002, Pages 8-18

  Guo, Caiying ^a   Yang, Wenyi ^a   Lobe, Corrinne G ^a,b,c  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c DEPARTMENT OF RADIATION ONCOLOGY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; TAMOXIFEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CLONE; CONTROLLED STUDY; EMBRYO CELL; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC RECOMBINATION; GESTATIONAL AGE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REPORTER GENE; STEM CELL; TRANSGENE; TRANSGENIC MOUSE;

MUS MUSCULUS;

EID: 0036164048     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.10021     Document Type: Article

References (48)

1. Studies on the properties of P1 site-specific recombination: Evidence for topologically unlinked products following recombination
2. Tet B or not tet B: Advances in tetracyclineinducible gene expression
3. A chimeric Cre recombinase inducible by synthetic, but not by natural ligands of the glucocorticoid receptor
4. Spatio-temporally controlled site-specific somatic mutagenesis in the mouse
5. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase
6. Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas
7. Ligand-activated site-specific recombination in mice
8. Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains
9. Reversible tumorigenesis by MYC in hematopoietic lineages
10. Conditional control of gene expression in the mammary gland
11. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
12. Site-specific recombination by the bacteriophage P1 lox-Cre system. Cre-mediated synapsis of two lox sites
13. Targeting of cre to the foxg1 (BF-1) locus mediates 1oxP recombination in the telencephalon and other developing head structures
14. The right time and place for molecular scissors
15. Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes
16. Selective ablation of retinoid X receptor alpha in hepatocytes impairs their lifespan and regenerative capacity
17. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifen- inducible Cre-ER(T) and Cre-ER(T2) recombinases
18. Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands
19. Inducible site-specific recombination in the brain
20. Regulation of Cre recombinase activity by the synthetic steroid RU 486
21. Temporally controlled somatic mutagenesis in smooth muscle
22. Inducible gene targeting in mice
23. Targeted oncogene activity by site-specific recombination in transgenic mice
24. Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development
25. Zp3-cre, a transgenic mouse line for the activation or inactivation of 1oxP-flanked target genes specifically in the female germ line
26. Z/AP, a double reporter for cre-mediated recombination
27. Conditional genome alteration in mice
28. Recent advances in gene mutagenesis by site-directed recombination
29. Site-and time-specific gene targeting in the mouse
30. Conditional sitespecific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase
31. Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase
32. An efficient salt-chloroform extraction of DNA from blood and tissues
33. Cre recombinase: The universal reagent for genome tailoring
34. Derivation of completely cell culture-derived mice from earlypassage embryonic stem cells
35. Efficient selection for high-expression transfectants with a novel eukaryotic vector
36. Z/EG, a double reporter transgenic mouse line that expresses enhanced green fluorescent protein upon Cre-mediated recombination
37. Conditional gene targeting
38. Functional expression of the cre-lox site-specific recombination sytem in the yeast Saccharomyces cerevisiae
39. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1
40. Temporally and spatially regulated somatic mutagenesis in mice
41. Switching on gene expression
42. Early mouse development: Lessons from gene targeting
43. Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: Generation and characterization of T cell-specific Stat3-deficient mice
44. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory
45. Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes
46. Temporal spatial, and cell type-specific control of Cre-mediated DNA recombination in transgenic mice
47. Comparison of the tamoxifen regulated chimeric Cre recombinases MerCreMer and CreMer
48. Non-injection methods for the production of embryonic stem cell-embryo chimeras