SCOPUS 정보 검색 플랫폼

ChemBioChem

Volumn 12, Issue 10, 2011, Pages 1529-1535

Manipulating the Expression Rate and Enantioselectivity of an Epoxide Hydrolase by Using Directed Evolution

(2) Reetz, Manfred T a,b Zheng, Huabao a

a MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG (Germany)

b PHILIPPS UNIVERSITY MARBURG (Germany)

Author keywords

Casting; Directed evolution; Enantioselectivity; Epoxide hydrolase; Expression rate

Indexed keywords

BETA GALACTOSIDASE; BETA GALACTOSIDASE ALPHA; DIPHENYL ETHER; EPOXIDE HYDROLASE; GLYCIDYL PHENYL ETHER; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS NIGER; CATALYST; DIRECTED MOLECULAR EVOLUTION; ENANTIOSELECTIVITY; ENZYME BINDING; ESCHERICHIA COLI; ITERATIVE SATURATION MUTAGENESIS; KINETICS; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEREOCHEMISTRY;

ASPERGILLUS NIGER; BETA-GALACTOSIDASE; DIRECTED MOLECULAR EVOLUTION; EPOXIDE HYDROLASES; ESCHERICHIA COLI; GENE EXPRESSION; MODELS, MOLECULAR; MUTATION; RECOMBINANT PROTEINS; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

ASPERGILLUS NIGER;

EID: 79959709452 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201100078 Document Type: Article

Times cited : (25)

References (53)

1
- 79959755638
- Note
- Reviews of directed evolution:

2
- 78149432825
- M. T. Reetz, Angew. Chem. 2011, 123, 144-182; Angew. Chem. Int. Ed. 2011, 50, 138-174;
- (2011) Angew. Chem. 2011, 123, 144-182; Angew. Chem. Int. Ed. , vol.50 , pp. 138-174
- Reetz, M.T.¹

3
- 33744512606
- T. W. Johannes, H. Zhao, Curr. Opin. Microbiol. 2006, 9, 261-267;
- (2006) Curr. Opin. Microbiol. , vol.9 , pp. 261-267
- Johannes, T.W.¹ Zhao, H.²

4
- 84891562596
- Wiley-VCH, Weinheim
- S. Lutz, U. T. Bornscheuer, Protein Engineering Handbook, Vols. 1-2, Wiley-VCH, Weinheim, 2009;
- (2009) Protein Engineering Handbook, Vols. 1-2
- Lutz, S.¹ Bornscheuer, U.T.²

5
- 68049106179
- N. J. Turner, Nat. Chem. Biol. 2009, 5, 567-573;
- (2009) Nat. Chem. Biol. , vol.5 , pp. 567-573
- Turner, N.J.¹

6
- 48249098990
- C. Jäckel, P. Kast, D. Hilvert, Annu. Rev. Biophys. Biomol. Struct. 2008, 37, 153-173;
- (2008) Annu. Rev. Biophys. Biomol. Struct. , vol.37 , pp. 153-173
- Jäckel, C.¹ Kast, P.² Hilvert, D.³

7
- 43049123356
- S. Bershtein; D. S. Tawfik, Curr. Opin. Chem. Biol. 2008, 12, 151-158; D. S. Tawfik, Curr. Opin. Chem. Biol. 2008, 12, 151-158;
- (2008) Curr. Opin. Chem. Biol. 2008, 12, 151-158; , Curr. Opin. Chem. Biol. , vol.12 , pp. 151-158
- Tawfik, S.B.D.S.¹ Tawfik, D.S.²

8
- 70450242805
- P. A. Romero, F. H. Arnold, Nat. Rev. Mol. Cell Biol. 2009, 10, 866-876;
- (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 866-876
- Romero, P.A.¹ Arnold, F.H.²

9
- 84891038850
- in (Eds.: V. Gotor, I. Alfonso, E. García-Urdiales), Wiley-VCH, Weinheim
- M. T. Reetz in Asymmetric Organic Synthesis with Enzymes (Eds.: V. Gotor, I. Alfonso, E. García-Urdiales), Wiley-VCH, Weinheim, 2008; pp. 21-63;
- (2008) Asymmetric Organic Synthesis with Enzymes , pp. 21-63
- Reetz, M.T.¹

10
- 71849104042
- L. G. Otten, F. Hollmann, I. W. C. E. Arends, Trends Biotechnol. 2010, 28, 46-54;
- (2010) Trends Biotechnol. , vol.28 , pp. 46-54
- Otten, L.G.¹ Hollmann, F.² Arends, I.W.C.E.³

11
- 65249152992
- A. V. Shivange, J. Marienhagen, H. Mundhada, A. Schenk, U. Schwaneberg, Curr. Opin. Chem. Biol. 2009, 13, 19-25.
- (2009) Curr. Opin. Chem. Biol. , vol.13 , pp. 19-25
- Shivange, A.V.¹ Marienhagen, J.² Mundhada, H.³ Schenk, A.⁴ Schwaneberg, U.⁵

12
- 57549110825
- J.-L. Reymond, V. S. Fluxà, N. Maillard, Chem. Commun. 2009, 34-46;
- (2009) Chem. Commun. , pp. 34-46
- Reymond, J.-L.¹ Fluxà, V.S.² Maillard, N.³

13
- 84889807359
- Wiley-VCH, Weinheim
- J.-L. Reymond, Enzyme Assays, High-Throughput Screening, Genetic Selection and Fingerprinting, Wiley-VCH, Weinheim, 2006.
- (2006) Enzyme Assays, High-Throughput Screening, Genetic Selection and Fingerprinting
- Reymond, J.-L.¹

14
- 3543106035
- S. Lutz, W. M. Patrick, Curr. Opin. Biotechnol. 2004, 15, 291-297;
- (2004) Curr. Opin. Biotechnol. , vol.15 , pp. 291-297
- Lutz, S.¹ Patrick, W.M.²

15
- 39149125127
- R. J. Fox, G. W. Huisman, Trends Biotechnol. 2008, 26, 132-138;
- (2008) Trends Biotechnol. , vol.26 , pp. 132-138
- Fox, R.J.¹ Huisman, G.W.²

16
- 29144503012
- T. S. Wong, D. Roccatano, M. Zacharias, U. Schwaneberg, J. Mol. Biol. 2006, 355, 858-871;
- (2006) J. Mol. Biol. , vol.355 , pp. 858-871
- Wong, T.S.¹ Roccatano, D.² Zacharias, M.³ Schwaneberg, U.⁴

17
- 23044501802
- J. D. Bloom, M. M. Meyer, P. Meinhold, C. R. Otey, D. MacMillan, F. H. Arnold, Curr. Opin. Struct. Biol. 2005, 15, 447-452.
- (2005) Curr. Opin. Struct. Biol. , vol.15 , pp. 447-452
- Bloom, J.D.¹ Meyer, M.M.² Meinhold, P.³ Otey, C.R.⁴ MacMillan, D.⁵ Arnold, F.H.⁶

18
- 54349090614
- M. T. Reetz, D. Kahakeaw, R. Lohmer, ChemBioChem 2008, 9, 1797-1804;
- (2008) ChemBioChem , vol.9 , pp. 1797-1804
- Reetz, M.T.¹ Kahakeaw, D.² Lohmer, R.³

19
- 54349117265
- M. T. Reetz, J. Sanchis, ChemBioChem 2008, 9, 2260-2267.
- (2008) ChemBioChem , vol.9 , pp. 2260-2267
- Reetz, M.T.¹ Sanchis, J.²

20
- 79959689372
- M. T. Reetz, L.-W. Wang, M. Bocola, Angew. Chem. 2006, 118, 1258-1263; Erratum: p. 2556; Angew. Chem. Int. Ed. 2006, 45, 1236-1241; Erratum: p. 2494;
- M. T. Reetz, L.-W. Wang, M. Bocola, Angew. Chem. 2006, 118, 1258-1263; Erratum: p. 2556; Angew. Chem. Int. Ed. 2006, 45, 1236-1241; Erratum: p. 2494;

21
- 73349113954
- D. J. Bougioukou, S. Kille, A. Taglieber, M. T. Reetz, Adv. Synth. Catal. 2009, 351, 3287-3305;
- (2009) Adv. Synth. Catal. , vol.351 , pp. 3287-3305
- Bougioukou, D.J.¹ Kille, S.² Taglieber, A.³ Reetz, M.T.⁴

22
- 77954274719
- M. T. Reetz, S. Prasad, J. D. Carballeira, Y. Gumulya, M. Bocola, J. Am. Chem. Soc. 2010, 132, 9144-9152;
- (2010) J. Am. Chem. Soc. , vol.132 , pp. 9144-9152
- Reetz, M.T.¹ Prasad, S.² Carballeira, J.D.³ Gumulya, Y.⁴ Bocola, M.⁵

23
- 78149259021
- H. Zheng, M. T. Reetz, J. Am. Chem. Soc. 2010, 132, 15744-15751;
- (2010) J. Am. Chem. Soc. , vol.132 , pp. 15744-15751
- Zheng, H.¹ Reetz, M.T.²

24
- 70350292190
- M. T. Reetz, S. Wu, J. Am. Chem. Soc. 2009, 131, 15424-15432.
- (2009) J. Am. Chem. Soc. , vol.131 , pp. 15424-15432
- Reetz, M.T.¹ Wu, S.²

25
- 34248567845
- M. T. Reetz, J. D. Carballeira, Nat. Protoc. 2007, 2, 891-903.
- (2007) Nat. Protoc. , vol.2 , pp. 891-903
- Reetz, M.T.¹ Carballeira, J.D.²

26
- 0842325300
- M. T. Reetz, C. Torre, A. Eipper, R. Lohmer, M. Hermes, B. Brunner, A. Maichele, M. Bocola, M. Arand, A. Cronin, Y. Genzel, A. Archelas, R. Furstoss, Org. Lett. 2004, 6, 177-180.
- (2004) Org. Lett. , vol.6 , pp. 177-180
- Reetz, M.T.¹ Torre, C.² Eipper, A.³ Lohmer, R.⁴ Hermes, M.⁵ Brunner, B.⁶ Maichele, A.⁷ Bocola, M.⁸ Arand, M.⁹ Cronin, A.¹⁰ Genzel, Y.¹¹ Archelas, A.¹² Furstoss, R.¹³

27
- 79959729737
- See for example:
- See for example:

28
- 0029828233
- S. C. Makrides, Microbiol. Rev. 1996, 60, 512-538;
- (1996) Microbiol. Rev. , vol.60 , pp. 512-538
- Makrides, S.C.¹

29
- 7444229263
- G. Marsischky, J. LaBaer, Genome Res. 2004, 14, 2020-2028;
- (2004) Genome Res. , vol.14 , pp. 2020-2028
- Marsischky, G.¹ LaBaer, J.²

30
- 56649111369
- E. Antipov, A. E. Cho, K. D. Wittrup, A. M. Klibanov, Proc. Natl. Acad. Sci. USA 2008, 105, 17694-17699;
- (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 17694-17699
- Antipov, E.¹ Cho, A.E.² Wittrup, K.D.³ Klibanov, A.M.⁴

31
- 33947138087
- A. Kern, E. Tilley, I. S. Hunter, M. Legiša, A. Glieder, J. Biotechnol. 2006, 129, 6-29.
- (2006) J. Biotechnol. , vol.129 , pp. 6-29
- Kern, A.¹ Tilley, E.² Hunter, I.S.³ Legiša, M.⁴ Glieder, A.⁵

32
- 79959713512
- Examples of manipulating the expression rate of enzymes by protein engineering:
- Examples of manipulating the expression rate of enzymes by protein engineering:

33
- 0025960319
- N. J. Silman, M. A. Carver, C. W. Jones, J. Gen. Microbiol. 1991, 137, 169-178;
- (1991) J. Gen. Microbiol. , vol.137 , pp. 169-178
- Silman, N.J.¹ Carver, M.A.² Jones, C.W.³

34
- 0141858719
- C. Bessler, J. Schmitt, K.-H. Maurer, R. D. Schmid, Protein Sci. 2003, 12, 2141-2149;
- (2003) Protein Sci. , vol.12 , pp. 2141-2149
- Bessler, C.¹ Schmitt, J.² Maurer, K.-H.³ Schmid, R.D.⁴

35
- 0037322616
- T. Bulter, M. Alcalde, V. Sieber, P. Meinhold, C. Schlachtbauer, F. H. Arnold, Appl. Environ. Microbiol. 2003, 69, 987-995;
- (2003) Appl. Environ. Microbiol. , vol.69 , pp. 987-995
- Bulter, T.¹ Alcalde, M.² Sieber, V.³ Meinhold, P.⁴ Schlachtbauer, C.⁵ Arnold, F.H.⁶

36
- 0037417871
- S. R. Leong, J. C. C. Chang, R. Ong, G. Dawes, W. P. C. Stemmer, J. Punnonen, Proc. Natl. Acad. Sci. USA 2003, 100, 1163-1168;
- (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1163-1168
- Leong, S.R.¹ Chang, J.C.C.² Ong, R.³ Dawes, G.⁴ Stemmer, W.P.C.⁵ Punnonen, J.⁶

37
- 0037304389
- G. S. Waldo, Curr. Opin. Chem. Biol. 2003, 7, 33-38;
- (2003) Curr. Opin. Chem. Biol. , vol.7 , pp. 33-38
- Waldo, G.S.¹

38
- 4544244867
- V. G. H. Eijsink, A. Bjørk, S. Gåseidnes, R. Sirevåg, B. Synstad, B. van den Burg, G. Vriend, J. Biotechnol. 2004, 113, 105-120;
- (2004) J. Biotechnol. , vol.113 , pp. 105-120
- Eijsink, V.G.H.¹ Bjørk, A.² Gåseidnes, S.³ Sirevåg, R.⁴ Synstad, B.⁵ van den Burg, B.⁶ Vriend, G.⁷

39
- 0442295054
- F. Cedrone, S. Niel, S. Roca, T. Bhatnagar, N. Ait-Abdelkader, C. Torre, H. Krumm, A. Maichele, M. T. Reetz, J. C. Baratti, Biocatal. Biotransform. 2003, 21, 357-364;
- (2003) Biocatal. Biotransform. , vol.21 , pp. 357-364
- Cedrone, F.¹ Niel, S.² Roca, S.³ Bhatnagar, T.⁴ Ait-Abdelkader, N.⁵ Torre, C.⁶ Krumm, H.⁷ Maichele, A.⁸ Reetz, M.T.⁹ Baratti, J.C.¹⁰

40
- 18044363663
- I. Matsumura, L. A. Rowe, Biomol. Eng. 2005, 22, 73-79;
- (2005) Biomol. Eng. , vol.22 , pp. 73-79
- Matsumura, I.¹ Rowe, L.A.²

41
- 18144390545
- S. Y. McLoughlin, C. Jackson, J.-W. Liu, D. Ollis, Protein Expr. Purif. 2005, 41, 433-440;
- (2005) Protein Expr. Purif. , vol.41 , pp. 433-440
- McLoughlin, S.Y.¹ Jackson, C.² Liu, J.-W.³ Ollis, D.⁴

42
- 13844281394
- C. Roodveldt, A. Aharoni, D. S. Tawfik, Curr. Opin. Struct. Biol. 2005, 15, 50-56;
- (2005) Curr. Opin. Struct. Biol. , vol.15 , pp. 50-56
- Roodveldt, C.¹ Aharoni, A.² Tawfik, D.S.³

43
- 33744496331
- R. Woodyer, W. A. van der Donk, H. Zhao, Comb. Chem. High Throughput Screening 2006, 9, 237-245;
- (2006) Comb. Chem. High Throughput Screening , vol.9 , pp. 237-245
- Woodyer, R.¹ van der Donk, W.A.² Zhao, H.³

44
- 33644846817
- Y.-S. Kim, R. Bhandari, J. R. Cochran, J. Kuriyan, K. D. Wittrup, Proteins Struct. Funct. Bioinf. 2006, 62, 1026-1035;
- (2006) Proteins Struct. Funct. Bioinf. , vol.62 , pp. 1026-1035
- Kim, Y.-S.¹ Bhandari, R.² Cochran, J.R.³ Kuriyan, J.⁴ Wittrup, K.D.⁵

45
- 34249938132
- J.-W. Li, J.-L. Zheng, X.-W. Wang, M. Jin, F.-H. Chao, Biomed. Environ. Sci. 2007, 20, 113-118;
- (2007) Biomed. Environ. Sci. , vol.20 , pp. 113-118
- Li, J.-W.¹ Zheng, J.-L.² Wang, X.-W.³ Jin, M.⁴ Chao, F.-H.⁵

46
- 51649106477
- P. K. R. Kambam, D. J. Sayut, Y. Niu, D. T. Eriksen, L. Sun, Biotechnol. Bioeng. 2008, 101, 263-272;
- (2008) Biotechnol. Bioeng. , vol.101 , pp. 263-272
- Kambam, P.K.R.¹ Sayut, D.J.² Niu, Y.³ Eriksen, D.T.⁴ Sun, L.⁵

47
- 54449087770
- C. A. Sarkar, I. Dodevski, M. Kenig, S. Dudli, A. Mohr, E. Hermanns, A. Plückthun, Proc. Natl. Acad. Sci. USA 2008, 105, 14804-14813.
- (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 14804-14813
- Sarkar, C.A.¹ Dodevski, I.² Kenig, M.³ Dudli, S.⁴ Mohr, A.⁵ Hermanns, E.⁶ Plückthun, A.⁷

48
- 0033015460
- G. S. Waldo, B. M. Standish, J. Berendzen, T. C. Terwilliger, Nat. Biotechnol. 1999, 17, 691-695.
- (1999) Nat. Biotechnol. , vol.17 , pp. 691-695
- Waldo, G.S.¹ Standish, B.M.² Berendzen, J.³ Terwilliger, T.C.⁴

49
- 0032824503
- K. L. Maxwell, A. K. Mittermaier, J. D. Forman-Kay, A. R. Davidson, Protein Sci. 1999, 8, 1908-1911.
- (1999) Protein Sci. , vol.8 , pp. 1908-1911
- Maxwell, K.L.¹ Mittermaier, A.K.² Forman-Kay, J.D.³ Davidson, A.R.⁴

50
- 0035130371
- W. C. Wigley, R. D. Stidham, N. M. Smith, J. F. Hunt, P. J. Thomas, Nat. Biotechnol. 2001, 19, 131-136.
- (2001) Nat. Biotechnol. , vol.19 , pp. 131-136
- Wigley, W.C.¹ Stidham, R.D.² Smith, N.M.³ Hunt, J.F.⁴ Thomas, P.J.⁵

51
- 0034651639
- J. Y. Zou, B. M. Hallberg, T. Bergfors, F. Oesch, M. Arand, S. L. Mowbray, T. A. Jones, Structure 2000, 8, 111-122;
- (2000) Structure , vol.8 , pp. 111-122
- Zou, J.Y.¹ Hallberg, B.M.² Bergfors, T.³ Oesch, F.⁴ Arand, M.⁵ Mowbray, S.L.⁶ Jones, T.A.⁷

52
- 0036841628
- Details of QuikChange Protocol of Stratagene
- Details of QuikChange Protocol of Stratagene: H. H. Hogrefe, J. Cline, G. L. Youngblood, R. M. Allen, BioTechniques 2002, 33, 1158-1165.
- (2002) BioTechniques , vol.33 , pp. 1158-1165
- Hogrefe, H.H.¹ Cline, J.² Youngblood, G.L.³ Allen, R.M.⁴

53
- 67349270900
- D. G. Gibson, L. Young, R.-Y. Chuang, J. C. Venter, C. A. Hutchison, H. O. Smith, Nat. Methods 2009, 6, 343-345.
- (2009) Nat. Methods , vol.6 , pp. 343-345
- Gibson, D.G.¹ Young, L.² Chuang, R.-Y.³ Venter, J.C.⁴ Hutchison, C.A.⁵ Smith, H.O.⁶

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.