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Volumn 38, Issue 7, 2011, Pages 441-450

Chronic kidney disease growth factors in renal fibrosis

Author keywords

Bone morphogenic protein 7; Connective tissue growth factor; Growth factors; Platelet derived growth factor; Transforming growth factor ; Vascular endothelial growth factor

Indexed keywords

BIOLOGICAL MARKER; CONNECTIVE TISSUE GROWTH FACTOR; GROWTH FACTOR; IMATINIB; MITOGENIC AGENT; OSTEOGENIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA3; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3;

EID: 79959702777     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2011.05487.x     Document Type: Review
Times cited : (77)

References (96)
  • 2
    • 78049369136 scopus 로고    scopus 로고
    • Renal fibrosis - novel insights into mechanisms and therapeutic targets
    • Boor P, Ostendorf T, Floege J. Renal fibrosis - novel insights into mechanisms and therapeutic targets. Nat. Rev. Nephrol. 2010; 6: 643-56.
    • (2010) Nat. Rev. Nephrol. , vol.6 , pp. 643-656
    • Boor, P.1    Ostendorf, T.2    Floege, J.3
  • 3
    • 66449132648 scopus 로고    scopus 로고
    • Polyclonal immunoglobulin G ameliorates the course of progressive mesangioproliferative glomerulonephritis in rats
    • Boor P, Kunter U. Polyclonal immunoglobulin G ameliorates the course of progressive mesangioproliferative glomerulonephritis in rats. Kidney Blood Press. Res. 2009; 32: 169-74.
    • (2009) Kidney Blood Press. Res. , vol.32 , pp. 169-174
    • Boor, P.1    Kunter, U.2
  • 4
    • 15844395661 scopus 로고    scopus 로고
    • Therapeutic targets for prevention and regression of progressive fibrosing renal diseases
    • Eitner F, Floege J. Therapeutic targets for prevention and regression of progressive fibrosing renal diseases. Curr. Opin. Investig. Drugs 2005; 6: 255-61.
    • (2005) Curr. Opin. Investig. Drugs , vol.6 , pp. 255-261
    • Eitner, F.1    Floege, J.2
  • 7
    • 49949092931 scopus 로고    scopus 로고
    • Mice overexpressing latent TGFbeta1 are protected against renal fibrosis in obstructive kidney disease
    • Huang XR, Chung AC, Wang XJ, Lai KN, Lan HY. Mice overexpressing latent TGFbeta1 are protected against renal fibrosis in obstructive kidney disease. Am. J. Physiol. Renal Physiol. 2008; 295: F118-27.
    • (2008) Am. J. Physiol. Renal Physiol. , vol.295
    • Huang, X.R.1    Chung, A.C.2    Wang, X.J.3    Lai, K.N.4    Lan, H.Y.5
  • 9
    • 77957252460 scopus 로고    scopus 로고
    • Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells
    • Koesters R, Kaissling B, Lehir M et al. Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. Am. J. Pathol. 2010; 177: 632-43.
    • (2010) Am. J. Pathol. , vol.177 , pp. 632-643
    • Koesters, R.1    Kaissling, B.2    Lehir, M.3
  • 10
    • 0026799402 scopus 로고
    • Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
    • Shull MM, Ormsby I, Kier AB et al. Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 1992; 359: 693-9.
    • (1992) Nature , vol.359 , pp. 693-699
    • Shull, M.M.1    Ormsby, I.2    Kier, A.B.3
  • 11
    • 0036181284 scopus 로고    scopus 로고
    • Gene transfer of Smad7 using electroporation of adenovirus prevents renal fibrosis in post-obstructed kidney
    • Terada Y, Hanada S, Nakao A, Kuwahara M, Sasaki S, Marumo F. Gene transfer of Smad7 using electroporation of adenovirus prevents renal fibrosis in post-obstructed kidney. Kidney Int. 2002; 61: 94-8.
    • (2002) Kidney Int. , vol.61 , pp. 94-98
    • Terada, Y.1    Hanada, S.2    Nakao, A.3    Kuwahara, M.4    Sasaki, S.5    Marumo, F.6
  • 12
    • 0037498439 scopus 로고    scopus 로고
    • Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model
    • Lan HY, Mu W, Tomita N et al. Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model. J. Am. Soc. Nephrol. 2003; 14: 1535-48.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 1535-1548
    • Lan, H.Y.1    Mu, W.2    Tomita, N.3
  • 13
    • 14644431025 scopus 로고    scopus 로고
    • Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney
    • Hou CC, Wang W, Huang XR et al. Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney. Am. J. Pathol. 2005; 166: 761-71.
    • (2005) Am. J. Pathol. , vol.166 , pp. 761-771
    • Hou, C.C.1    Wang, W.2    Huang, X.R.3
  • 14
    • 3242797424 scopus 로고    scopus 로고
    • Smad3 deficiency attenuates renal fibrosis, inflammation, and apoptosis after unilateral ureteral obstruction
    • Inazaki K, Kanamaru Y, Kojima Y et al. Smad3 deficiency attenuates renal fibrosis, inflammation, and apoptosis after unilateral ureteral obstruction. Kidney Int. 2004; 66: 597-604.
    • (2004) Kidney Int. , vol.66 , pp. 597-604
    • Inazaki, K.1    Kanamaru, Y.2    Kojima, Y.3
  • 15
    • 0346727324 scopus 로고    scopus 로고
    • Targeted disruption of TGFbeta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
    • Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A. Targeted disruption of TGFbeta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J. Clin. Invest. 2003; 112: 1486-94.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1486-1494
    • Sato, M.1    Muragaki, Y.2    Saika, S.3    Roberts, A.B.4    Ooshima, A.5
  • 16
    • 77956548300 scopus 로고    scopus 로고
    • Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis
    • Meng XM, Huang XR, Chung AC et al. Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis. J. Am. Soc. Nephrol. 2010; 21: 1477-87.
    • (2010) J. Am. Soc. Nephrol. , vol.21 , pp. 1477-1487
    • Meng, X.M.1    Huang, X.R.2    Chung, A.C.3
  • 17
    • 33646709433 scopus 로고    scopus 로고
    • Ubiquitin-dependent degradation of SnoN and Ski is increased in renal fibrosis induced by obstructive injury
    • Fukasawa H, Yamamoto T, Togawa A et al. Ubiquitin-dependent degradation of SnoN and Ski is increased in renal fibrosis induced by obstructive injury. Kidney Int. 2006; 69: 1733-40.
    • (2006) Kidney Int. , vol.69 , pp. 1733-1740
    • Fukasawa, H.1    Yamamoto, T.2    Togawa, A.3
  • 18
    • 0347282737 scopus 로고    scopus 로고
    • Downregulation of Smad transcriptional corepressors SnoN and Ski in the fibrotic kidney: An amplification mechanism for TGF-beta1 signaling
    • Yang J, Zhang X, Li Y, Liu Y. Downregulation of Smad transcriptional corepressors SnoN and Ski in the fibrotic kidney: An amplification mechanism for TGF-beta1 signaling. J. Am. Soc. Nephrol. 2003; 14: 3167-77.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 3167-3177
    • Yang, J.1    Zhang, X.2    Li, Y.3    Liu, Y.4
  • 19
    • 33748939751 scopus 로고    scopus 로고
    • IN-1130, a novel transforming growth factor-beta type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy
    • Moon JA, Kim HT, Cho IS, Sheen YY, Kim DK. IN-1130, a novel transforming growth factor-beta type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy. Kidney Int. 2006; 70: 1234-43.
    • (2006) Kidney Int. , vol.70 , pp. 1234-1243
    • Moon, J.A.1    Kim, H.T.2    Cho, I.S.3    Sheen, Y.Y.4    Kim, D.K.5
  • 20
    • 19444371555 scopus 로고    scopus 로고
    • Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factorbeta type I receptor kinase in puromycin-induced nephritis
    • Grygielko ET, Martin WM, Tweed C et al. Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factorbeta type I receptor kinase in puromycin-induced nephritis. J. Pharmacol. Exp. Ther. 2005; 313: 943-51.
    • (2005) J. Pharmacol. Exp. Ther. , vol.313 , pp. 943-951
    • Grygielko, E.T.1    Martin, W.M.2    Tweed, C.3
  • 21
    • 33847656703 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen-activated protein kinase and transforming growth factor-beta1/Smad signaling pathways modulates the development of fibrosis in adriamycin-induced nephropathy
    • Li J, Campanale NV, Liang RJ, Deane JA, Bertram JF, Ricardo SD. Inhibition of p38 mitogen-activated protein kinase and transforming growth factor-beta1/Smad signaling pathways modulates the development of fibrosis in adriamycin-induced nephropathy. Am. J. Pathol. 2006; 169: 1527-40.
    • (2006) Am. J. Pathol. , vol.169 , pp. 1527-1540
    • Li, J.1    Campanale, N.V.2    Liang, R.J.3    Deane, J.A.4    Bertram, J.F.5    Ricardo, S.D.6
  • 22
    • 33749007708 scopus 로고    scopus 로고
    • Intracellular delivery of the p38 mitogen-activated protein kinase inhibitor SB202190 [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole] in renal tubular cells: A novel strategy to treat renal fibrosis
    • Prakash J, Sandovici M, Saluja V et al. Intracellular delivery of the p38 mitogen-activated protein kinase inhibitor SB202190 [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole] in renal tubular cells: A novel strategy to treat renal fibrosis. J. Pharmacol. Exp. Ther. 2006; 319: 8-19.
    • (2006) J. Pharmacol. Exp. Ther. , vol.319 , pp. 8-19
    • Prakash, J.1    Sandovici, M.2    Saluja, V.3
  • 24
    • 0036118493 scopus 로고    scopus 로고
    • Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction
    • Schaefer L, Macakova K, Raslik I et al. Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction. Am. J. Pathol. 2002; 160: 1181-91.
    • (2002) Am. J. Pathol. , vol.160 , pp. 1181-1191
    • Schaefer, L.1    Macakova, K.2    Raslik, I.3
  • 25
    • 0029905441 scopus 로고    scopus 로고
    • Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney
    • Isaka Y, Brees DK, Ikegaya K et al. Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney. Nat. Med. 1996; 2: 418-23.
    • (1996) Nat. Med. , vol.2 , pp. 418-423
    • Isaka, Y.1    Brees, D.K.2    Ikegaya, K.3
  • 27
    • 33847682663 scopus 로고    scopus 로고
    • MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors
    • Kato M, Zhang J, Wang M et al. MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proc. Natl. Acad. Sci. U S A 2007; 104: 3432-7.
    • (2007) Proc. Natl. Acad. Sci. U S A , vol.104 , pp. 3432-3437
    • Kato, M.1    Zhang, J.2    Wang, M.3
  • 29
    • 67449155931 scopus 로고    scopus 로고
    • Circulating transforming growth factor-beta1 levels and the risk for kidney disease in African Americans
    • Suthanthiran M, Gerber LM, Schwartz JE et al. Circulating transforming growth factor-beta1 levels and the risk for kidney disease in African Americans. Kidney Int. 2009; 76: 72-80.
    • (2009) Kidney Int. , vol.76 , pp. 72-80
    • Suthanthiran, M.1    Gerber, L.M.2    Schwartz, J.E.3
  • 30
    • 0142169489 scopus 로고    scopus 로고
    • Transforming growth factor beta and progression of renal disease
    • August P, Suthanthiran M. Transforming growth factor beta and progression of renal disease. Kidney Int. Suppl. 2003; 87: S99-104.
    • (2003) Kidney Int. Suppl. , vol.87
    • August, P.1    Suthanthiran, M.2
  • 31
    • 79551493014 scopus 로고    scopus 로고
    • Association of advanced vasculopathy and transforming growth factor-beta1 gene expression with immunoglobulin A nephropathy progression
    • Brabcova I, Tesar V, Honsova E et al. Association of advanced vasculopathy and transforming growth factor-beta1 gene expression with immunoglobulin A nephropathy progression. Nephrol. Dial. Transplant. 2011; 26: 573-79.
    • (2011) Nephrol. Dial. Transplant. , vol.26 , pp. 573-579
    • Brabcova, I.1    Tesar, V.2    Honsova, E.3
  • 33
    • 33644864525 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 and the kidney: Current concepts and open questions
    • Zeisberg M. Bone morphogenic protein-7 and the kidney: Current concepts and open questions. Nephrol. Dial. Transplant. 2006; 21: 568-73.
    • (2006) Nephrol. Dial. Transplant. , vol.21 , pp. 568-573
    • Zeisberg, M.1
  • 35
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
    • Zeisberg M, Hanai J, Sugimoto H et al. BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat. Med. 2003; 9: 964-8.
    • (2003) Nat. Med. , vol.9 , pp. 964-968
    • Zeisberg, M.1    Hanai, J.2    Sugimoto, H.3
  • 36
    • 0242582117 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models
    • Zeisberg M, Bottiglio C, Kumar N et al. Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. Am. J. Physiol. Renal Physiol. 2003; 285: F1060-7.
    • (2003) Am. J. Physiol. Renal Physiol. , vol.285
    • Zeisberg, M.1    Bottiglio, C.2    Kumar, N.3
  • 37
    • 14844290237 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney
    • Zeisberg M, Shah AA, Kalluri R. Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney. J. Biol. Chem. 2005; 280: 8094-100.
    • (2005) J. Biol. Chem. , vol.280 , pp. 8094-8100
    • Zeisberg, M.1    Shah, A.A.2    Kalluri, R.3
  • 38
    • 17544379605 scopus 로고    scopus 로고
    • Osteogenic protein-1 prevents renal fibrogenesis associated with ureteral obstruction
    • Hruska KA, Guo G, Wozniak M et al. Osteogenic protein-1 prevents renal fibrogenesis associated with ureteral obstruction. Am. J. Physiol. Renal Physiol. 2000; 279: F130-43.
    • (2000) Am. J. Physiol. Renal Physiol. , vol.279
    • Hruska, K.A.1    Guo, G.2    Wozniak, M.3
  • 39
    • 0037648482 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy
    • Wang S, Chen Q, Simon TC et al. Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy. Kidney Int. 2003; 63: 2037-49.
    • (2003) Kidney Int. , vol.63 , pp. 2037-2049
    • Wang, S.1    Chen, Q.2    Simon, T.C.3
  • 41
    • 17644378679 scopus 로고    scopus 로고
    • Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease
    • Lin J, Patel SR, Cheng X et al. Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease. Nat. Med. 2005; 11: 387-93.
    • (2005) Nat. Med. , vol.11 , pp. 387-393
    • Lin, J.1    Patel, S.R.2    Cheng, X.3
  • 42
    • 33748427629 scopus 로고    scopus 로고
    • Modulator of bone morphogenetic protein activity in the progression of kidney diseases
    • Yanagita M. Modulator of bone morphogenetic protein activity in the progression of kidney diseases. Kidney Int. 2006; 70: 989-93.
    • (2006) Kidney Int. , vol.70 , pp. 989-993
    • Yanagita, M.1
  • 43
    • 77949745693 scopus 로고    scopus 로고
    • Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome
    • Tanaka M, Asada M, Higashi AY et al. Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome. J. Clin. Invest. 2010; 120: 768-77.
    • (2010) J. Clin. Invest. , vol.120 , pp. 768-777
    • Tanaka, M.1    Asada, M.2    Higashi, A.Y.3
  • 44
    • 70849136597 scopus 로고    scopus 로고
    • Connective tissue growth factor-(CTGF, CCN2) - a marker, mediator and therapeutic target for renal fibrosis
    • Phanish MK, Winn SK, Dockrell ME. Connective tissue growth factor-(CTGF, CCN2) - a marker, mediator and therapeutic target for renal fibrosis. Nephron Exp. Nephrol. 2010; 114: e83-92.
    • (2010) Nephron Exp. Nephrol. , vol.114
    • Phanish, M.K.1    Winn, S.K.2    Dockrell, M.E.3
  • 45
    • 65649136944 scopus 로고    scopus 로고
    • CCN3 (NOV) is a negative regulator of CCN2 (CTGF) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease
    • Riser BL, Najmabadi F, Perbal B et al. CCN3 (NOV) is a negative regulator of CCN2 (CTGF) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease. Am. J. Pathol. 2009; 174: 1725-34.
    • (2009) Am. J. Pathol. , vol.174 , pp. 1725-1734
    • Riser, B.L.1    Najmabadi, F.2    Perbal, B.3
  • 46
    • 77249149862 scopus 로고    scopus 로고
    • CCN3/CCN2 regulation and the fibrosis of diabetic renal disease
    • Riser BL, Najmabadi F, Perbal B et al. CCN3/CCN2 regulation and the fibrosis of diabetic renal disease. J. Cell Commun. Signal. 2010; 4: 39-50.
    • (2010) J. Cell Commun. Signal. , vol.4 , pp. 39-50
    • Riser, B.L.1    Najmabadi, F.2    Perbal, B.3
  • 47
    • 37249021044 scopus 로고    scopus 로고
    • CCN3 is a novel endogenous PDGF-regulated inhibitor of glomerular cell proliferation
    • van Roeyen CR, Eitner F, Scholl T et al. CCN3 is a novel endogenous PDGF-regulated inhibitor of glomerular cell proliferation. Kidney Int. 2008; 73: 86-94.
    • (2008) Kidney Int. , vol.73 , pp. 86-94
    • van Roeyen, C.R.1    Eitner, F.2    Scholl, T.3
  • 48
    • 4043089953 scopus 로고    scopus 로고
    • Connective tissue growth factor and renal diseases: Some answers, more questions
    • Abdel Wahab N, Mason RM. Connective tissue growth factor and renal diseases: Some answers, more questions. Curr. Opin. Nephrol. Hypertens. 2004; 13: 53-8.
    • (2004) Curr. Opin. Nephrol. Hypertens. , vol.13 , pp. 53-58
    • Abdel Wahab, N.1    Mason, R.M.2
  • 49
    • 33748031093 scopus 로고    scopus 로고
    • Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: Implications for diabetic renal disease
    • Burns WC, Twigg SM, Forbes JM et al. Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: Implications for diabetic renal disease. J. Am. Soc. Nephrol. 2006; 17: 2484-94.
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 2484-2494
    • Burns, W.C.1    Twigg, S.M.2    Forbes, J.M.3
  • 50
    • 21044454845 scopus 로고    scopus 로고
    • Connective tissue growth factor expressed in tubular epithelium plays a pivotal role in renal fibrogenesis
    • Okada H, Kikuta T, Kobayashi T et al. Connective tissue growth factor expressed in tubular epithelium plays a pivotal role in renal fibrogenesis. J. Am. Soc. Nephrol. 2005; 16: 133-43.
    • (2005) J. Am. Soc. Nephrol. , vol.16 , pp. 133-143
    • Okada, H.1    Kikuta, T.2    Kobayashi, T.3
  • 51
    • 13444250205 scopus 로고    scopus 로고
    • Imbalance of growth factor signalling in diabetic kidney disease: Is connective tissue growth factor (CTGF, CCN2) the perfect intervention point?
    • van Nieuwenhoven FA, Jensen LJ, Flyvbjerg A, Goldschmeding R. Imbalance of growth factor signalling in diabetic kidney disease: Is connective tissue growth factor (CTGF, CCN2) the perfect intervention point? Nephrol. Dial. Transplant. 2005; 20: 6-10.
    • (2005) Nephrol. Dial. Transplant. , vol.20 , pp. 6-10
    • van Nieuwenhoven, F.A.1    Jensen, L.J.2    Flyvbjerg, A.3    Goldschmeding, R.4
  • 52
    • 2542473312 scopus 로고    scopus 로고
    • Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis
    • Yokoi H, Mukoyama M, Nagae T et al. Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis. J. Am. Soc. Nephrol. 2004; 15: 1430-40.
    • (2004) J. Am. Soc. Nephrol. , vol.15 , pp. 1430-1440
    • Yokoi, H.1    Mukoyama, M.2    Nagae, T.3
  • 53
    • 9644284528 scopus 로고    scopus 로고
    • Advanced glycation end-products induce connective tissue growth factor-mediated renal fibrosis predominantly through transforming growth factor betaindependent pathway
    • Zhou G, Li C, Cai L. Advanced glycation end-products induce connective tissue growth factor-mediated renal fibrosis predominantly through transforming growth factor betaindependent pathway. Am. J. Pathol. 2004; 165: 2033-43.
    • (2004) Am. J. Pathol. , vol.165 , pp. 2033-2043
    • Zhou, G.1    Li, C.2    Cai, L.3
  • 54
    • 48649102468 scopus 로고    scopus 로고
    • Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy
    • Nguyen TQ, Tarnow L, Jorsal A et al. Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy. Diabetes Care 2008; 31: 1177-82.
    • (2008) Diabetes Care , vol.31 , pp. 1177-1182
    • Nguyen, T.Q.1    Tarnow, L.2    Jorsal, A.3
  • 55
    • 43249099025 scopus 로고    scopus 로고
    • Connective tissue growth factor and susceptibility to renal and vascular disease risk in type 1 diabetes
    • Jaffa AA, Usinger WR, McHenry MB et al. Connective tissue growth factor and susceptibility to renal and vascular disease risk in type 1 diabetes. J. Clin. Endocrinol. Metab. 2008; 93: 1893-900.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 1893-1900
    • Jaffa, A.A.1    Usinger, W.R.2    McHenry, M.B.3
  • 56
    • 2942682928 scopus 로고    scopus 로고
    • Regulation of PDGF and its receptors in fibrotic diseases
    • Bonner JC. Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev. 2004; 15: 255-73.
    • (2004) Cytokine Growth Factor Rev. , vol.15 , pp. 255-273
    • Bonner, J.C.1
  • 57
    • 38149107161 scopus 로고    scopus 로고
    • A new look at platelet-derived growth factor in renal disease
    • Floege J, Eitner F, Alpers CE. A new look at platelet-derived growth factor in renal disease. J. Am. Soc. Nephrol. 2008; 19: 12-23.
    • (2008) J. Am. Soc. Nephrol. , vol.19 , pp. 12-23
    • Floege, J.1    Eitner, F.2    Alpers, C.E.3
  • 58
    • 0035034653 scopus 로고    scopus 로고
    • Specific antagonism of PDGF prevents renal scarring in experimental glomerulonephritis
    • Ostendorf T, Kunter U, Grone HJ et al. Specific antagonism of PDGF prevents renal scarring in experimental glomerulonephritis. J. Am. Soc. Nephrol. 2001; 12: 909-18.
    • (2001) J. Am. Soc. Nephrol. , vol.12 , pp. 909-918
    • Ostendorf, T.1    Kunter, U.2    Grone, H.J.3
  • 59
    • 0029869237 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB induces renal tubulointerstitial myofibroblast formation and tubulointerstitial fibrosis
    • Tang WW, Ulich TR, Lacey DL et al. Platelet-derived growth factor-BB induces renal tubulointerstitial myofibroblast formation and tubulointerstitial fibrosis. Am. J. Pathol. 1996; 148: 1169-80.
    • (1996) Am. J. Pathol. , vol.148 , pp. 1169-1180
    • Tang, W.W.1    Ulich, T.R.2    Lacey, D.L.3
  • 60
    • 0141857170 scopus 로고    scopus 로고
    • Obstructive uropathy in mice and humans: Potential role for PDGF-D in the progression of tubulointerstitial injury
    • Taneda S, Hudkins KL, Topouzis S et al. Obstructive uropathy in mice and humans: Potential role for PDGF-D in the progression of tubulointerstitial injury. J. Am. Soc. Nephrol. 2003; 14: 2544-55.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 2544-2555
    • Taneda, S.1    Hudkins, K.L.2    Topouzis, S.3
  • 61
    • 0942265458 scopus 로고    scopus 로고
    • Exogenous PDGF-D is a potent mesangial cell mitogen and causes a severe mesangial proliferative glomerulopathy
    • Hudkins KL, Gilbertson DG, Carling M et al. Exogenous PDGF-D is a potent mesangial cell mitogen and causes a severe mesangial proliferative glomerulopathy. J. Am. Soc. Nephrol. 2004; 15: 286-98.
    • (2004) J. Am. Soc. Nephrol. , vol.15 , pp. 286-298
    • Hudkins, K.L.1    Gilbertson, D.G.2    Carling, M.3
  • 62
    • 10744223785 scopus 로고    scopus 로고
    • A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis
    • Ostendorf T, van Roeyen CR, Peterson JD et al. A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis. J. Am. Soc. Nephrol. 2003; 14: 2237-47.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 2237-2247
    • Ostendorf, T.1    van Roeyen, C.R.2    Peterson, J.D.3
  • 63
    • 33645471300 scopus 로고    scopus 로고
    • Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis
    • Ostendorf T, Rong S, Boor P et al. Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis. J. Am. Soc. Nephrol. 2006; 17: 1054-62.
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 1054-1062
    • Ostendorf, T.1    Rong, S.2    Boor, P.3
  • 64
    • 34248154137 scopus 로고    scopus 로고
    • PDGF-D inhibition by CR002 ameliorates tubulointerstitial fibrosis following experimental glomerulonephritis
    • Boor P, Konieczny A, Villa L et al. PDGF-D inhibition by CR002 ameliorates tubulointerstitial fibrosis following experimental glomerulonephritis. Nephrol. Dial. Transplant. 2007; 22: 1323-31.
    • (2007) Nephrol. Dial. Transplant. , vol.22 , pp. 1323-1331
    • Boor, P.1    Konieczny, A.2    Villa, L.3
  • 65
    • 69249123225 scopus 로고    scopus 로고
    • Patients with IgA nephropathy exhibit high systemic PDGF-DD levels
    • Boor P, Eitner F, Cohen CD et al. Patients with IgA nephropathy exhibit high systemic PDGF-DD levels. Nephrol. Dial. Transplant. 2009; 24: 2755-62.
    • (2009) Nephrol. Dial. Transplant. , vol.24 , pp. 2755-2762
    • Boor, P.1    Eitner, F.2    Cohen, C.D.3
  • 66
    • 44649087678 scopus 로고    scopus 로고
    • [Expression and clinical implication of plateletderived growth factor-D and platelet-derived growth factor-beta in childhood IgA nephropathy]
    • Rong ZH, Wang C, Hao J, Duan HJ. [Expression and clinical implication of plateletderived growth factor-D and platelet-derived growth factor-beta in childhood IgA nephropathy]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2008; 20: 275-8.
    • (2008) Zhongguo Wei Zhong Bing Ji Jiu Yi Xue , vol.20 , pp. 275-278
    • Rong, Z.H.1    Wang, C.2    Hao, J.3    Duan, H.J.4
  • 68
    • 0030822654 scopus 로고    scopus 로고
    • Long-term effects of erythropoietin therapy on fistula stenosis and plasma concentrations of PDGF and MCP-1 in hemodialysis patients
    • De Marchi S, Cecchin E, Falleti E et al. Long-term effects of erythropoietin therapy on fistula stenosis and plasma concentrations of PDGF and MCP-1 in hemodialysis patients. J. Am. Soc. Nephrol. 1997; 8: 1147-56.
    • (1997) J. Am. Soc. Nephrol. , vol.8 , pp. 1147-1156
    • De Marchi, S.1    Cecchin, E.2    Falleti, E.3
  • 69
    • 0037406877 scopus 로고    scopus 로고
    • PDGF-C expression in the developing and normal adult human kidney and in glomerular diseases
    • Eitner F, Ostendorf T, Kretzler M et al. PDGF-C expression in the developing and normal adult human kidney and in glomerular diseases. J. Am. Soc. Nephrol. 2003; 14: 1145-53.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 1145-1153
    • Eitner, F.1    Ostendorf, T.2    Kretzler, M.3
  • 70
    • 0036208983 scopus 로고    scopus 로고
    • Expression of a novel PDGF isoform, PDGF-C, in normal and diseased rat kidney
    • Eitner F, Ostendorf T, Van Roeyen C et al. Expression of a novel PDGF isoform, PDGF-C, in normal and diseased rat kidney. J. Am. Soc. Nephrol. 2002; 13: 910-17.
    • (2002) J. Am. Soc. Nephrol. , vol.13 , pp. 910-917
    • Eitner, F.1    Ostendorf, T.2    Van Roeyen, C.3
  • 71
    • 0035002453 scopus 로고    scopus 로고
    • Effects of PDGF A-chain antisense oligodeoxynucleotides on growth of cardiovascular organs in stroke-prone spontaneously hypertensive rats
    • Kishioka H, Fukuda N, Wen-Yang H, Nakayama M, Watanabe Y, Kanmatsuse K. Effects of PDGF A-chain antisense oligodeoxynucleotides on growth of cardiovascular organs in stroke-prone spontaneously hypertensive rats. Am. J. Hypertens. 2001; 14: 439-45.
    • (2001) Am. J. Hypertens. , vol.14 , pp. 439-445
    • Kishioka, H.1    Fukuda, N.2    Wen-Yang, H.3    Nakayama, M.4    Watanabe, Y.5    Kanmatsuse, K.6
  • 72
    • 39049115240 scopus 로고    scopus 로고
    • PDGF-C is a proinflammatory cytokine that mediates renal interstitial fibrosis
    • Eitner F, Bucher E, van Roeyen C et al. PDGF-C is a proinflammatory cytokine that mediates renal interstitial fibrosis. J. Am. Soc. Nephrol. 2008; 19: 281-9.
    • (2008) J. Am. Soc. Nephrol. , vol.19 , pp. 281-289
    • Eitner, F.1    Bucher, E.2    van Roeyen, C.3
  • 73
    • 77954611970 scopus 로고    scopus 로고
    • PDGF-C mediates glomerular capillary repair
    • Boor P, van Roeyen CR, Kunter U et al. PDGF-C mediates glomerular capillary repair. Am. J. Pathol. 2010; 177: 58-69.
    • (2010) Am. J. Pathol. , vol.177 , pp. 58-69
    • Boor, P.1    van Roeyen, C.R.2    Kunter, U.3
  • 74
    • 11244292291 scopus 로고    scopus 로고
    • Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo
    • Wang S, Wilkes MC, Leof EB, Hirschberg R. Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo. FASEB J. 2005; 19: 1-11.
    • (2005) FASEB J. , vol.19 , pp. 1-11
    • Wang, S.1    Wilkes, M.C.2    Leof, E.B.3    Hirschberg, R.4
  • 75
    • 20544477176 scopus 로고    scopus 로고
    • Imatinib attenuates diabetic nephropathy in apolipoprotein E-knockout mice
    • Lassila M, Jandeleit-Dahm K, Seah KK et al. Imatinib attenuates diabetic nephropathy in apolipoprotein E-knockout mice. J. Am. Soc. Nephrol. 2005; 16: 363-73.
    • (2005) J. Am. Soc. Nephrol. , vol.16 , pp. 363-373
    • Lassila, M.1    Jandeleit-Dahm, K.2    Seah, K.K.3
  • 76
    • 0037469034 scopus 로고    scopus 로고
    • Chronic allograft nephropathy is prevented by inhibition of platelet-derived growth factor receptor: Tyrosine kinase inhibitors as a potential therapy
    • Savikko J, Taskinen E, Von Willebrand E. Chronic allograft nephropathy is prevented by inhibition of platelet-derived growth factor receptor: Tyrosine kinase inhibitors as a potential therapy. Transplantation 2003; 75: 1147-53.
    • (2003) Transplantation , vol.75 , pp. 1147-1153
    • Savikko, J.1    Taskinen, E.2    Von Willebrand, E.3
  • 77
    • 33746845181 scopus 로고    scopus 로고
    • Cardiotoxicity of the cancer therapeutic agent imatinib mesylate
    • Kerkela R, Grazette L, Yacobi R et al. Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat. Med. 2006; 12: 908-16.
    • (2006) Nat. Med. , vol.12 , pp. 908-916
    • Kerkela, R.1    Grazette, L.2    Yacobi, R.3
  • 78
    • 33646482407 scopus 로고    scopus 로고
    • Altered bone and mineral metabolism in patients receiving imatinib mesylate
    • Berman E, Nicolaides M, Maki RG et al. Altered bone and mineral metabolism in patients receiving imatinib mesylate. N. Engl. J. Med. 2006; 354: 2006-13.
    • (2006) N. Engl. J. Med. , vol.354 , pp. 2006-2013
    • Berman, E.1    Nicolaides, M.2    Maki, R.G.3
  • 79
    • 34250374471 scopus 로고    scopus 로고
    • Role of the VEGF - a signaling pathway in the glomerulus: Evidence for crosstalk between components of the glomerular filtration barrier
    • Eremina V, Baelde HJ, Quaggin SE. Role of the VEGF - a signaling pathway in the glomerulus: Evidence for crosstalk between components of the glomerular filtration barrier. Nephron Physiol. 2007; 106: p32-7.
    • (2007) Nephron Physiol. , vol.106
    • Eremina, V.1    Baelde, H.J.2    Quaggin, S.E.3
  • 80
    • 33645452371 scopus 로고    scopus 로고
    • Chronic hypoxia and tubulointerstitial injury: A final common pathway to end-stage renal failure
    • Nangaku M. Chronic hypoxia and tubulointerstitial injury: A final common pathway to end-stage renal failure. J. Am. Soc. Nephrol. 2006; 17: 17-25.
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 17-25
    • Nangaku, M.1
  • 81
    • 63849250731 scopus 로고    scopus 로고
    • Angiogenesis in the kidney: A new therapeutic target?
    • Lerman LO, Chade AR. Angiogenesis in the kidney: A new therapeutic target? Curr. Opin. Nephrol. Hypertens. 2009; 18: 160-5.
    • (2009) Curr. Opin. Nephrol. Hypertens. , vol.18 , pp. 160-165
    • Lerman, L.O.1    Chade, A.R.2
  • 82
    • 0037227496 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: A new player in the pathogenesis of renal fibrosis
    • Kang DH, Johnson RJ. Vascular endothelial growth factor: A new player in the pathogenesis of renal fibrosis. Curr. Opin. Nephrol. Hypertens. 2003; 12: 43-9.
    • (2003) Curr. Opin. Nephrol. Hypertens. , vol.12 , pp. 43-49
    • Kang, D.H.1    Johnson, R.J.2
  • 83
    • 0034917262 scopus 로고    scopus 로고
    • Impaired angiogenesis in the remnant kidney model: II. Vascular endothelial growth factor administration reduces renal fibrosis and stabilizes renal function
    • Kang DH, Hughes J, Mazzali M, Schreiner GF, Johnson RJ. Impaired angiogenesis in the remnant kidney model: II. Vascular endothelial growth factor administration reduces renal fibrosis and stabilizes renal function. J. Am. Soc. Nephrol. 2001; 12: 1448-57.
    • (2001) J. Am. Soc. Nephrol. , vol.12 , pp. 1448-1457
    • Kang, D.H.1    Hughes, J.2    Mazzali, M.3    Schreiner, G.F.4    Johnson, R.J.5
  • 84
    • 14344270356 scopus 로고    scopus 로고
    • Post-cyclosporine-mediated hypertension and nephropathy: Amelioration by vascular endothelial growth factor
    • Kang DH, Kim YG, Andoh TF et al. Post-cyclosporine-mediated hypertension and nephropathy: Amelioration by vascular endothelial growth factor. Am. J. Physiol. Renal Physiol. 2001; 280: F727-36.
    • (2001) Am. J. Physiol. Renal Physiol. , vol.280
    • Kang, D.H.1    Kim, Y.G.2    Andoh, T.F.3
  • 85
    • 0035034655 scopus 로고    scopus 로고
    • Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes
    • de Vriese AS, Tilton RG, Elger M, Stephan CC, Kriz W, Lameire NH. Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes. J. Am. Soc. Nephrol. 2001; 12: 993-1000.
    • (2001) J. Am. Soc. Nephrol. , vol.12 , pp. 993-1000
    • de Vriese, A.S.1    Tilton, R.G.2    Elger, M.3    Stephan, C.C.4    Kriz, W.5    Lameire, N.H.6
  • 87
    • 0036241828 scopus 로고    scopus 로고
    • High protein-induced glomerular hypertrophy is vascular endothelial growth factor-dependent
    • Schrijvers BF, Rasch R, Tilton RG, Flyvbjerg A. High protein-induced glomerular hypertrophy is vascular endothelial growth factor-dependent. Kidney Int. 2002; 61: 1600-4.
    • (2002) Kidney Int. , vol.61 , pp. 1600-1604
    • Schrijvers, B.F.1    Rasch, R.2    Tilton, R.G.3    Flyvbjerg, A.4
  • 88
    • 0036789207 scopus 로고    scopus 로고
    • Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody
    • Flyvbjerg A, Dagnaes-Hansen F, De Vriese AS, Schrijvers BF, Tilton RG, Rasch R. Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody. Diabetes 2002; 51: 3090-4.
    • (2002) Diabetes , vol.51 , pp. 3090-3094
    • Flyvbjerg, A.1    Dagnaes-Hansen, F.2    De Vriese, A.S.3    Schrijvers, B.F.4    Tilton, R.G.5    Rasch, R.6
  • 89
    • 57349093841 scopus 로고    scopus 로고
    • VEGF-121 preserves renal microvessel structure and ameliorates secondary renal disease following acute kidney injury
    • Leonard EC, Friedrich JL, Basile DP. VEGF-121 preserves renal microvessel structure and ameliorates secondary renal disease following acute kidney injury. Am J Physiol RenalPhysiol. 2008; 295: F1648-57.
    • (2008) Am J Physiol RenalPhysiol. , vol.295
    • Leonard, E.C.1    Friedrich, J.L.2    Basile, D.P.3
  • 90
    • 73649087608 scopus 로고    scopus 로고
    • Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease
    • Hakroush S, Moeller MJ, Theilig F et al. Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease. Am. J. Pathol. 2009; 175: 1883-95.
    • (2009) Am. J. Pathol. , vol.175 , pp. 1883-1895
    • Hakroush, S.1    Moeller, M.J.2    Theilig, F.3
  • 91
    • 58849142993 scopus 로고    scopus 로고
    • Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism
    • Mu W, Long DA, Ouyang X et al. Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism. Am. J. Physiol. Renal Physiol. 2009; 296: F145-52.
    • (2009) Am. J. Physiol. Renal Physiol. , vol.296
    • Mu, W.1    Long, D.A.2    Ouyang, X.3
  • 92
    • 63949084807 scopus 로고    scopus 로고
    • Lymphatic vessels develop during tubulointerstitial fibrosis
    • Sakamoto I, Ito Y, Mizuno M et al. Lymphatic vessels develop during tubulointerstitial fibrosis. Kidney Int. 2009; 75: 828-38.
    • (2009) Kidney Int. , vol.75 , pp. 828-838
    • Sakamoto, I.1    Ito, Y.2    Mizuno, M.3
  • 93
    • 0041342011 scopus 로고    scopus 로고
    • Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: Aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels
    • Matsui K, Nagy-Bojarsky K, Laakkonen P et al. Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: Aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels. J. Am. Soc. Nephrol. 2003; 14: 1981-9.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 1981-1989
    • Matsui, K.1    Nagy-Bojarsky, K.2    Laakkonen, P.3
  • 94
    • 38949132160 scopus 로고    scopus 로고
    • Disturbance of lymph circulation develops renal fibrosis in rats with or without contralateral nephrectomy
    • Zhang T, Guan G, Liu G et al. Disturbance of lymph circulation develops renal fibrosis in rats with or without contralateral nephrectomy. Nephrology (Carlton) 2008; 13: 128-38.
    • (2008) Nephrology (Carlton) , vol.13 , pp. 128-138
    • Zhang, T.1    Guan, G.2    Liu, G.3
  • 95
    • 66349123367 scopus 로고    scopus 로고
    • Functional, histological and biochemical consequences of renal lymph disorder in mononephrectomized rats
    • Zhang T, Liu G, Sun M, Guan G, Chen B, Li X. Functional, histological and biochemical consequences of renal lymph disorder in mononephrectomized rats. J. Nephrol. 2009; 22: 109-16.
    • (2009) J. Nephrol. , vol.22 , pp. 109-116
    • Zhang, T.1    Liu, G.2    Sun, M.3    Guan, G.4    Chen, B.5    Li, X.6
  • 96
    • 43449098197 scopus 로고    scopus 로고
    • A phase I study of CR002, a fully-human monoclonal antibody against platelet-derived growth factor-D
    • Hawthorne T, Giot L, Blake L et al. A phase I study of CR002, a fully-human monoclonal antibody against platelet-derived growth factor-D. Int. J. Clin. Pharmacol. Ther. 2008; 46: 236-44.
    • (2008) Int. J. Clin. Pharmacol. Ther. , vol.46 , pp. 236-244
    • Hawthorne, T.1    Giot, L.2    Blake, L.3


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