Similarities and differences between primary and secondary degeneration of the optic nerve and the effect of minocycline

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 249, Issue 6, 2011, Pages 849-857

  Levkovitch Verbin, Hani ^a   Spierer, Oriel ^a   Vander, Shelly ^a   Dardik, Rima ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Apoptosis; Glaucoma; Minocycline; Optic nerve; Secondary degeneration

Indexed keywords

CYCLIN DEPENDENT KINASE 2; EI24 PROTEIN; FLUOROGOLD; GADD45 ALPHA PROTEIN; GENE PRODUCT; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; INHIBITOR OF APOPTOSIS PROTEIN 1; MINOCYCLINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CDK2 GENE; CELL LABELING; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; EI24 GENE; FAS LIGAND GENE; GADD45ALPHA GENE; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; IAP 1 GENE; IMMUNOHISTOCHEMISTRY; INTERLEUKIN 18 GENE; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPTIC NERVE DISEASE; PRIMARY OPTIC NERVE DEGENERATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA GANGLION CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECONDARY OPTIC NERVE DEGENERATION; SUPERIOR COLLICULUS; TNF ALPHA GENE; UPREGULATION;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CELL CYCLE PROTEINS; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE 2; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; INHIBITOR OF APOPTOSIS PROTEINS; INJECTIONS, INTRAPERITONEAL; MINOCYCLINE; NERVE CRUSH; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; NUCLEAR PROTEINS; OPTIC NERVE DISEASES; RATS; RATS, WISTAR; RETINAL GANGLION CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 79959700033     PISSN: 0721832X     EISSN: 1435702X     Source Type: Journal    
DOI: 10.1007/s00417-010-1608-2     Document Type: Article

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