H NMR spectroscopy-based metabolomic assessment of uremic toxicity, with toxicological outcomes, in male rats following an acute, mid-life insult from ochratoxin A

Toxins

Volumn 3, Issue 6, 2011, Pages 504-519

  Mantle, Peter G ^a   Nicholls, Andrew W ^b   Shockcor, John P ^c  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c WATERS CORPORATION   (United States)

Author keywords

Metabolomics; Nephropathy; Ochratoxin A; Pharmacokinetics; Polyuria; Toxicology

Indexed keywords

CREATININE; GLYCINE DERIVATIVE; OCHRATOXIN; PHENYLACETYLGLYCINE; PHOSPHATE; TRIMETHYLAMINE OXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; CONTROLLED STUDY; CREATININE URINE LEVEL; KIDNEY FUNCTION; MALE; METABOLOMICS; NEPHROTOXICITY; NONHUMAN; OUTCOME ASSESSMENT; PHOSPHATE URINE LEVEL; POLYURIA; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; TOXICITY TESTING; TOXIN ANALYSIS; TOXIN SYNTHESIS; UREMIA; URINALYSIS; URINARY EXCRETION; URINE VOLUME; WEIGHT REDUCTION;

AGING; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; KIDNEY FUNCTION TESTS; KIDNEY NEOPLASMS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLOMICS; OCHRATOXINS; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, INBRED F344; TOXICITY TESTS, ACUTE; UREMIA; URINALYSIS;

ANIMALIA; RATTUS;

EID: 79959668683     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/toxins3060504     Document Type: Article

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