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Volumn 48, Issue 11, 2010, Pages 3159-3166

Effects of fasting and gender on ochratoxin A toxicokinetics in F344 rats

Author keywords

Alpha 2u globulin; Bioavailability; Food; Male and female F344 rat; Ochratoxin A; Toxicokinetic

Indexed keywords

ALPHA 2U GLOBULIN; OCHRATOXIN;

EID: 77957360224     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.08.012     Document Type: Article
Times cited : (22)

References (46)
  • 2
    • 38649118476 scopus 로고    scopus 로고
    • Distribution of ochratoxin A in plasma and tissues of rats fed a naturally contaminated diet amended with micronized wheat fibres: effectiveness of mycotoxin sequestering activity
    • Aoudia N., Tangni E.K., Larondelle Y. Distribution of ochratoxin A in plasma and tissues of rats fed a naturally contaminated diet amended with micronized wheat fibres: effectiveness of mycotoxin sequestering activity. Food Chem. Toxicol. 2008, 46:871-878.
    • (2008) Food Chem. Toxicol. , vol.46 , pp. 871-878
    • Aoudia, N.1    Tangni, E.K.2    Larondelle, Y.3
  • 3
    • 34250762536 scopus 로고    scopus 로고
    • Assessment of the multi-mycotoxin-binding efficacy of a carbon/aluminosilicate-based product in an in vitro gastrointestinal model
    • Avantaggiato G., Havenaar R., Visconti A. Assessment of the multi-mycotoxin-binding efficacy of a carbon/aluminosilicate-based product in an in vitro gastrointestinal model. J. Agric. Food. Chem. 2007, 55:4810-4819.
    • (2007) J. Agric. Food. Chem. , vol.55 , pp. 4810-4819
    • Avantaggiato, G.1    Havenaar, R.2    Visconti, A.3
  • 4
    • 0003747347 scopus 로고
    • Icon Development Solutions, Ellicot City, Maryland, USA
    • Beal S.L., Sheiner L.B. NONMEM Useŕ's guide 1989-2006, Icon Development Solutions, Ellicot City, Maryland, USA.
    • (1989) NONMEM Useŕ's guide
    • Beal, S.L.1    Sheiner, L.B.2
  • 5
    • 0031751625 scopus 로고    scopus 로고
    • Regional selectivity to ochratoxin A, distribution and cytotoxicity in rat brain
    • Belmadani A., Tramu G., Betbeder A.M., Steyn P.S., Creppy E.E. Regional selectivity to ochratoxin A, distribution and cytotoxicity in rat brain. Arch. Toxicol. 1998, 72:656-662.
    • (1998) Arch. Toxicol. , vol.72 , pp. 656-662
    • Belmadani, A.1    Tramu, G.2    Betbeder, A.M.3    Steyn, P.S.4    Creppy, E.E.5
  • 7
    • 0037432669 scopus 로고    scopus 로고
    • Interaction of ochratoxin A with human intestinal Caco-2 cells: possible implication of a multidrug resistance-associated protein (MRP2)
    • Berger V., Gabriel A.F., Sergent T., Trouet A., Larondelle Y., Schneider Y.J. Interaction of ochratoxin A with human intestinal Caco-2 cells: possible implication of a multidrug resistance-associated protein (MRP2). Toxicol. Lett. 2003, 140-141:465-476.
    • (2003) Toxicol. Lett. , pp. 465-476
    • Berger, V.1    Gabriel, A.F.2    Sergent, T.3    Trouet, A.4    Larondelle, Y.5    Schneider, Y.J.6
  • 8
    • 0029040007 scopus 로고
    • Toxicokinetics of ochratoxin A in rat following intratracheal administration
    • Breitholtz-Emanuelsson A., Fuchs R., Hult K. Toxicokinetics of ochratoxin A in rat following intratracheal administration. Nat. Toxins 1995, 3:101-103.
    • (1995) Nat. Toxins , vol.3 , pp. 101-103
    • Breitholtz-Emanuelsson, A.1    Fuchs, R.2    Hult, K.3
  • 10
    • 55749101956 scopus 로고    scopus 로고
    • Efficacy of a new ochratoxin-binding agent (OcraTox) to counteract the deleterious effects of ochratoxin A in laying hens
    • Denli M., Blandon J.C., Guynot M.E., Salado S., Perez J.F. Efficacy of a new ochratoxin-binding agent (OcraTox) to counteract the deleterious effects of ochratoxin A in laying hens. Poult. Sci. 2008, 87:2266-2272.
    • (2008) Poult. Sci. , vol.87 , pp. 2266-2272
    • Denli, M.1    Blandon, J.C.2    Guynot, M.E.3    Salado, S.4    Perez, J.F.5
  • 11
    • 0035134037 scopus 로고    scopus 로고
    • A good practice guide to the administration of substances and removal of blood, including routes and volumes
    • European Federation of Pharmaceutical Industries Association and European Centre for the Validation of Alternative Methods
    • Diehl K.H., Hull R., Morton D., Pfister R., Rabemampianina Y., Smith D., Vidal J.M., van de Vorstenbosch C. A good practice guide to the administration of substances and removal of blood, including routes and volumes. J. Appl. Toxicol. 2001, 21:15-23. European Federation of Pharmaceutical Industries Association and European Centre for the Validation of Alternative Methods.
    • (2001) J. Appl. Toxicol. , vol.21 , pp. 15-23
    • Diehl, K.H.1    Hull, R.2    Morton, D.3    Pfister, R.4    Rabemampianina, Y.5    Smith, D.6    Vidal, J.M.7    van de Vorstenbosch, C.8
  • 12
    • 33645471606 scopus 로고    scopus 로고
    • Ochratoxin A: comparative pharmacokinetics and toxicological implications (experimental and domestic animals and humans)
    • Dietrich D.R., Heussner A.H., O'Brien E. Ochratoxin A: comparative pharmacokinetics and toxicological implications (experimental and domestic animals and humans). Food Addit. Contam. 2005, 22(Suppl 1):45-52.
    • (2005) Food Addit. Contam. , vol.22 , Issue.SUPPL. 1 , pp. 45-52
    • Dietrich, D.R.1    Heussner, A.H.2    O'Brien, E.3
  • 13
    • 33847112240 scopus 로고    scopus 로고
    • Opinion of the scientific panel on contaminants in the food chain on a request from the Commission related to ochratoxin A in food. Adopted on 4 April 2006
    • EFSA (European Food Safety Authority)
    • EFSA (European Food Safety Authority), 2006. Opinion of the scientific panel on contaminants in the food chain on a request from the Commission related to ochratoxin A in food. Adopted on 4 April 2006. The EFSA Journal 365, 1-56.
    • (2006) The EFSA Journal , vol.365 , pp. 1-56
  • 14
    • 0242350785 scopus 로고    scopus 로고
    • Guidance for industry
    • Food and Drug Administration, US Department of Health and Human Services, Center for Drug evaluation and research (CDER)
    • Food and Drug Administration, US Department of Health and Human Services, Center for Drug evaluation and research (CDER), 2002. Guidance for industry. Food-effect bioavailability and fed bioequivalence studies.
    • (2002) Food-effect bioavailability and fed bioequivalence studies
  • 15
    • 0018571123 scopus 로고
    • The pharmacokinetic profile of ochratoxin A in the rat after oral and intravenous administration
    • Galtier P., Charpenteau J.L., Alvinerie M., Labouche C. The pharmacokinetic profile of ochratoxin A in the rat after oral and intravenous administration. Drug Metab. Dispos. 1979, 7:429-434.
    • (1979) Drug Metab. Dispos. , vol.7 , pp. 429-434
    • Galtier, P.1    Charpenteau, J.L.2    Alvinerie, M.3    Labouche, C.4
  • 16
    • 0032961540 scopus 로고    scopus 로고
    • Altered plasma and brain disposition and pharmacodynamics of methadone in abstinent rats
    • Garrido M.J., Valle M., Calvo R., Troconiz I.F. Altered plasma and brain disposition and pharmacodynamics of methadone in abstinent rats. J. Pharmacol. Exp. Ther. 1999, 288:179-187.
    • (1999) J. Pharmacol. Exp. Ther. , vol.288 , pp. 179-187
    • Garrido, M.J.1    Valle, M.2    Calvo, R.3    Troconiz, I.F.4
  • 17
    • 0024597101 scopus 로고
    • Toxicokinetics of ochratoxin A in several species and its plasma-binding properties
    • Hagelberg S., Hult K., Fuchs R. Toxicokinetics of ochratoxin A in several species and its plasma-binding properties. J. Appl. Toxicol. 1989, 9:91-96.
    • (1989) J. Appl. Toxicol. , vol.9 , pp. 91-96
    • Hagelberg, S.1    Hult, K.2    Fuchs, R.3
  • 18
    • 0035919075 scopus 로고    scopus 로고
    • Mycotoxin detoxication of animal feed by different adsorbents
    • Huwig A., Freimund S., Kappeli O., Dutler H. Mycotoxin detoxication of animal feed by different adsorbents. Toxicol. Lett. 2001, 122:179-188.
    • (2001) Toxicol. Lett. , vol.122 , pp. 179-188
    • Huwig, A.1    Freimund, S.2    Kappeli, O.3    Dutler, H.4
  • 19
    • 0027527494 scopus 로고
    • IARC, Ochratoxin A. Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. IARC Monographs on the evaluation of carcinogenic risks to humans
    • IARC, 1993. Ochratoxin A. Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. IARC Monographs on the evaluation of carcinogenic risks to humans 56, 489-521.
    • (1993) , vol.56 , pp. 489-521
  • 20
    • 0022555463 scopus 로고
    • 3H]-label from low doses of radioactive ochratoxin A ingested by rats, and evidence for DNA single-strand breaks caused in liver and kidneys
    • 3H]-label from low doses of radioactive ochratoxin A ingested by rats, and evidence for DNA single-strand breaks caused in liver and kidneys. Arch. Toxicol. 1986, 58:219-224.
    • (1986) Arch. Toxicol. , vol.58 , pp. 219-224
    • Kane, A.1    Creppy, E.E.2    Roth, A.3    Roschenthaler, R.4    Dirheimer, G.5
  • 21
    • 0019997606 scopus 로고
    • Intestinal absorption and secretion of ochratoxin A in the rat
    • Kumagai S., Aibara K. Intestinal absorption and secretion of ochratoxin A in the rat. Toxicol. Appl. Pharmacol. 1982, 64:94-102.
    • (1982) Toxicol. Appl. Pharmacol. , vol.64 , pp. 94-102
    • Kumagai, S.1    Aibara, K.2
  • 23
    • 44649165139 scopus 로고    scopus 로고
    • Binding of a ochratoxin A to a urinary globulin: a new concept to account for gender difference in rat nephrocarcinogenic responses
    • Mantle P., Nagy J. Binding of a ochratoxin A to a urinary globulin: a new concept to account for gender difference in rat nephrocarcinogenic responses. Int. J. Mol. Sci. 2008, 9:719-735.
    • (2008) Int. J. Mol. Sci. , vol.9 , pp. 719-735
    • Mantle, P.1    Nagy, J.2
  • 24
    • 29544448684 scopus 로고    scopus 로고
    • Renal tumourigenesis in male rats in response to chronic dietary ochratoxin A
    • Mantle P., Kulinskaya E., Nestler S. Renal tumourigenesis in male rats in response to chronic dietary ochratoxin A. Food Addit. Contam. 2005, 22(Suppl 1):58-64.
    • (2005) Food Addit. Contam. , vol.22 , Issue.SUPPL. 1 , pp. 58-64
    • Mantle, P.1    Kulinskaya, E.2    Nestler, S.3
  • 25
    • 0037344929 scopus 로고    scopus 로고
    • Comparative responses to mode of oral administration and dose of ochratoxin A or nephrotoxic extract of Penicillium polonicum in rats
    • Miljkovic A., Pfohl-Leszkowicz A., Dobrota M., Mantle P.G. Comparative responses to mode of oral administration and dose of ochratoxin A or nephrotoxic extract of Penicillium polonicum in rats. Exp. Toxicol. Pathol. 2003, 54:305-312.
    • (2003) Exp. Toxicol. Pathol. , vol.54 , pp. 305-312
    • Miljkovic, A.1    Pfohl-Leszkowicz, A.2    Dobrota, M.3    Mantle, P.G.4
  • 26
    • 0013519855 scopus 로고
    • Toxicology and carcinogenesis studies of ochratoxin A (CAS No 303-47-9) in F344/N rats (gavage studies)
    • National Toxicology Program (NTP)
    • National Toxicology Program (NTP), 1989. Toxicology and carcinogenesis studies of ochratoxin A (CAS No 303-47-9) in F344/N rats (gavage studies). Nat. l Toxicol. Program Tech. Rep. Ser. 358, 1-142.
    • (1989) Nat. l Toxicol. Program Tech. Rep. Ser. , vol.358 , pp. 1-142
  • 28
    • 77957357655 scopus 로고    scopus 로고
    • OECD Guideline for testing of chemicals, Number 417. Adoped 4 April 1984, Toxicokinetics
    • OECD Guideline for testing of chemicals, Number 417. Adoped 4 April 1984, Toxicokinetics.
  • 29
    • 33846454704 scopus 로고    scopus 로고
    • Ochratoxin A: an overview on toxicity and carcinogenicity in animals and humans
    • Pfohl-Leszkowicz A., Manderville R.A. Ochratoxin A: an overview on toxicity and carcinogenicity in animals and humans. Mol. Nutr. Food Res. 2007, 51:61-99.
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 61-99
    • Pfohl-Leszkowicz, A.1    Manderville, R.A.2
  • 30
    • 0036161508 scopus 로고    scopus 로고
    • Balkan endemic nephropathy and associated urinary tract tumours: a review on aetiological causes and the potential role of mycotoxins
    • Pfohl-Leszkowicz A., Petkova-Bocharova T., Chernozemsky I.N., Castegnaro M. Balkan endemic nephropathy and associated urinary tract tumours: a review on aetiological causes and the potential role of mycotoxins. Food Addit. Contam. 2002, 19:282-302.
    • (2002) Food Addit. Contam. , vol.19 , pp. 282-302
    • Pfohl-Leszkowicz, A.1    Petkova-Bocharova, T.2    Chernozemsky, I.N.3    Castegnaro, M.4
  • 31
    • 0032586788 scopus 로고    scopus 로고
    • The role of alpha2u-globulin in ochratoxin A induced renal toxicity and tumors in F344 rats
    • Rasonyi T., Schlatter J., Dietrich D.R. The role of alpha2u-globulin in ochratoxin A induced renal toxicity and tumors in F344 rats. Toxicol. Lett. 1999, 104:83-92.
    • (1999) Toxicol. Lett. , vol.104 , pp. 83-92
    • Rasonyi, T.1    Schlatter, J.2    Dietrich, D.R.3
  • 33
    • 0027882438 scopus 로고
    • Interpretation of male rat renal tubule tumors
    • Rodgers I.S., Baetcke K.P. Interpretation of male rat renal tubule tumors. Environ. Health Perspect. 1993, 101(Suppl 6):45-52.
    • (1993) Environ. Health Perspect. , vol.101 , Issue.SUPPL. 6 , pp. 45-52
    • Rodgers, I.S.1    Baetcke, K.P.2
  • 35
    • 33645885302 scopus 로고    scopus 로고
    • Ochratoxin A secretion by ATP-dependent membrane transporters in Caco-2 cells
    • Schrickx J., Lektarau Y., Fink-Gremmels J. Ochratoxin A secretion by ATP-dependent membrane transporters in Caco-2 cells. Arch. Toxicol. 2006, 80:243-249.
    • (2006) Arch. Toxicol. , vol.80 , pp. 243-249
    • Schrickx, J.1    Lektarau, Y.2    Fink-Gremmels, J.3
  • 37
    • 0038558554 scopus 로고    scopus 로고
    • Strain-specific mammary proliferative lesion development following lifetime oral administration of ochratoxin A in DA and Lewis rats
    • Son W.C., Kamino K., Lee Y.S., Kang K.S. Strain-specific mammary proliferative lesion development following lifetime oral administration of ochratoxin A in DA and Lewis rats. Int. J. Cancer 2003, 105:305-311.
    • (2003) Int. J. Cancer , vol.105 , pp. 305-311
    • Son, W.C.1    Kamino, K.2    Lee, Y.S.3    Kang, K.S.4
  • 38
    • 0036176159 scopus 로고    scopus 로고
    • Spontaneous mycotoxic nephropathy in Bulgarian chickens with unclarified mycotoxin aetiology
    • Stoev S.D., Daskalov H., Radic B., Domijan A.M., Peraica M. Spontaneous mycotoxic nephropathy in Bulgarian chickens with unclarified mycotoxin aetiology. Vet. Res. 2002, 33:83-93.
    • (2002) Vet. Res. , vol.33 , pp. 83-93
    • Stoev, S.D.1    Daskalov, H.2    Radic, B.3    Domijan, A.M.4    Peraica, M.5
  • 39
    • 0017763466 scopus 로고
    • The pharmacokinetics of ochratoxin A in rats
    • Suzuki S., Satoh T., Yamazaki M. The pharmacokinetics of ochratoxin A in rats. Jpn. J. Pharmacol. 1977, 27:735-744.
    • (1977) Jpn. J. Pharmacol. , vol.27 , pp. 735-744
    • Suzuki, S.1    Satoh, T.2    Yamazaki, M.3
  • 40
    • 0027848920 scopus 로고
    • Alpha 2u-globulin nephropathy: review of the cellular and molecular mechanisms involved and their implications for human risk assessment
    • Swenberg J.A. Alpha 2u-globulin nephropathy: review of the cellular and molecular mechanisms involved and their implications for human risk assessment. Environ. Health Perspect. 1993, 101(Suppl 6):39-44.
    • (1993) Environ. Health Perspect. , vol.101 , Issue.SUPPL. 6 , pp. 39-44
    • Swenberg, J.A.1
  • 41
    • 9644282955 scopus 로고    scopus 로고
    • Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice
    • Tanaka Y., Slitt A.L., Leazer T.M., Maher J.M., Klaassen C.D. Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice. Biochem. Biophys. Res. Commun. 2005, 326:181-187.
    • (2005) Biochem. Biophys. Res. Commun. , vol.326 , pp. 181-187
    • Tanaka, Y.1    Slitt, A.L.2    Leazer, T.M.3    Maher, J.M.4    Klaassen, C.D.5
  • 42
    • 56949108305 scopus 로고    scopus 로고
    • Simple high-performance liquid chromatography-fluorescence detection method for plasma, kidney and liver of rat as a tool for toxicology studies
    • Vettorazzi A., Gonzalez-Peñas E., Arbillaga L., Corcuera L.A., Lopez de Cerain A. Simple high-performance liquid chromatography-fluorescence detection method for plasma, kidney and liver of rat as a tool for toxicology studies. J. Chromatogr. A 2008, 1215:100-106.
    • (2008) J. Chromatogr. A , vol.1215 , pp. 100-106
    • Vettorazzi, A.1    Gonzalez-Peñas, E.2    Arbillaga, L.3    Corcuera, L.A.4    Lopez de Cerain, A.5
  • 44
    • 0034848903 scopus 로고    scopus 로고
    • Proteins of rat serum, urine, and cerebrospinal fluid: VI. Further protein identifications and interstrain comparison
    • Wait R., Gianazza E., Eberini I., Sironi L., Dunn M.J., Gemeiner M., Miller I. Proteins of rat serum, urine, and cerebrospinal fluid: VI. Further protein identifications and interstrain comparison. Electrophoresis 2001, 22:3043-3052.
    • (2001) Electrophoresis , vol.22 , pp. 3043-3052
    • Wait, R.1    Gianazza, E.2    Eberini, I.3    Sironi, L.4    Dunn, M.J.5    Gemeiner, M.6    Miller, I.7
  • 45
    • 0003973194 scopus 로고    scopus 로고
    • Safety evaluation of certain mycotoxins in food
    • WHO (World Health Organisation), No. 47
    • WHO (World Health Organisation), 2001. Safety evaluation of certain mycotoxins in food. WHO Food Additives Series, No. 47.
    • (2001) WHO Food Additives Series
  • 46
    • 0141671914 scopus 로고    scopus 로고
    • Toxicokinetics of the mycotoxin ochratoxin A in F344 rats after oral administration
    • Zepnik H., Völkel W., Dekant W. Toxicokinetics of the mycotoxin ochratoxin A in F344 rats after oral administration. Toxicol. Appl. Pharmacol. 2003, 192:36-44.
    • (2003) Toxicol. Appl. Pharmacol. , vol.192 , pp. 36-44
    • Zepnik, H.1    Völkel, W.2    Dekant, W.3


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