The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy

DMM Disease Models and Mechanisms

Volumn 4, Issue 4, 2011, Pages 457-467

  Sleigh, James N ^a   Gillingwater, Thomas H ^b   Talbot, Kevin ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CRE RECOMBINASE; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; PROTEIN SM; SMALL NUCLEAR RIBONUCLEOPROTEIN; SMALL NUCLEAR RNA; SURVIVAL MOTOR NEURON PROTEIN; SURVIVAL MOTOR NEURON PROTEIN 2;

ADENO ASSOCIATED VIRUS; AMYOTROPHIC LATERAL SCLEROSIS; BIOGENESIS; CELL DEATH; CELL FUNCTION; CELL GROWTH; CELL LINE; CELL LOSS; CELL MATURATION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CHICKEN; DEVELOPMENT; DISEASE COURSE; DISEASE SEVERITY; DROSOPHILA; EXPERIMENTAL MODEL; GENE CONTROL; GENE DELETION; GENE FUNCTION; GENE MUTATION; INTRON; LOXP SITE; LUMBAR SPINAL CORD; MOTONEURON; MOUSE EMBRYO; NERVE CELL; NERVE DEGENERATION; NERVE ELONGATION; NERVE ENDING; NERVE EXCITABILITY; NERVOUS SYSTEM DEVELOPMENT; NEUROMUSCULAR SYNAPSE; NEUROMUSCULAR SYSTEM; NEUROPHYSIOLOGY; NONHUMAN; OLIGODENDROGLIA; PATHOGENESIS; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; REVIEW; RNA SPLICING; SPINAL GANGLION; SPINAL MUSCULAR ATROPHY; SUBSTITUTION THERAPY; THALAMUS; TRANSGENE; WERDNIG HOFFMANN DISEASE; XENOPUS LAEVIS;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; MICE; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; NERVE DEGENERATION; RNA SPLICING; SMN COMPLEX PROTEINS;

EID: 79959658484     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.007245     Document Type: Review

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