-
1
-
-
4544374528
-
BRCA1 and BRCA2: 1994 and beyond
-
DOI 10.1038/nrc1431
-
Narod SA, Foulkes WD. BRCA1 and BRCA2: 1994 and beyond. Nat Rev Cancer. 2004;4(9):665-76. (Pubitemid 39215065)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.9
, pp. 665-676
-
-
Narod, S.A.1
Foulkes, W.D.2
-
2
-
-
17344365851
-
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families
-
DOI 10.1086/301749
-
Ford D et al. Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium. Am J Hum Genet. 1998;62 (3):676-89. (Pubitemid 28164626)
-
(1998)
American Journal of Human Genetics
, vol.62
, Issue.3
, pp. 676-689
-
-
Ford, D.1
Easton, D.F.2
Stratton, M.3
Narod, S.4
Goldgar, D.5
Devilee, P.6
Bishop, D.T.7
Weber, B.8
Lenoir, G.9
Chang-Claude, J.10
Sobol, H.11
Teare, M.D.12
Struewing, J.13
Arason, A.14
Scherneck, S.15
Peto, J.16
Rebbeck, T.R.17
Tonin, P.18
Neuhausen, S.19
Barkardottir, R.20
Eyfjord, J.21
Lynch, H.22
Ponder, B.A.J.23
Gayther, S.A.24
Birch, J.M.25
Lindblom, A.26
Stoppa-Lyonnet, D.27
Bignon, Y.28
Borg, A.29
Hamann, U.30
Haites, N.31
Scott, R.J.32
Maugard, C.M.33
Vasen, H.34
Seitz, S.35
Cannon-Albright, L.A.36
Schofield, A.37
Zelada-Hedman, M.38
more..
-
3
-
-
33646570913
-
A genome wide linkage search for breast cancer susceptibility genes
-
DOI 10.1002/gcc.20330
-
Smith P et al. A genome wide linkage search for breast cancer susceptibility genes. Genes Chromosom Cancer. 2006;45(7):646-55. (Pubitemid 43727152)
-
(2006)
Genes Chromosomes and Cancer
, vol.45
, Issue.7
, pp. 646-655
-
-
Smith, P.1
McGuffog, L.2
Easton, D.F.3
Mann, G.J.4
Pupo, G.M.5
Newman, B.6
Chenevix-Trench, G.7
Szabo, C.8
Southey, M.9
Renard, H.10
Odefrey, F.11
Lynch, H.12
Stoppa-Lyonnet, D.13
Couch, F.14
Hopper, J.L.15
Giles, G.G.16
McCredie, M.R.E.17
Buys, S.18
Andrulis, I.19
Senie, R.20
Goldgar, D.E.21
Oldenburg, R.22
Kroeze-Jansema, K.23
Kraan, J.24
Meijers-Heijboer, H.25
Klijn, J.G.M.26
Van Asperen, C.27
Van Leeuwen, I.28
Vasen, H.F.A.29
Cornelisse, C.J.30
Devilee, P.31
Baskcomb, L.32
Seal, S.33
Barfoot, R.34
Mangion, J.35
Hall, A.36
Edkins, S.37
Rapley, E.38
Wooster, R.39
Chang-Claude, J.40
Eccles, D.41
Evans, D.G.42
Futreal, P.A.43
Nathanson, K.L.44
Weber, B.L.45
Rahman, N.46
Stratton, M.R.47
more..
-
4
-
-
45949085378
-
Polygenes, risk prediction, and targeted prevention of breast cancer
-
Pharoah PDP et al. Polygenes, risk prediction, and targeted prevention of breast cancer. N Engl J Med. 2008;358(26):2796-803.
-
(2008)
N Engl J Med
, vol.358
, Issue.26
, pp. 2796-2803
-
-
Pdp, P.1
-
5
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA et al. Finding the missing heritability of complex diseases. Nature. 2009;461(7265):747-53.
-
(2009)
Nature
, vol.461
, Issue.7265
, pp. 747-753
-
-
Manolio, T.A.1
-
6
-
-
75149189204
-
BRCA1 and its toolbox for the maintenance of genome integrity
-
Huen MS, Sy SM, Chen J. BRCA1 and its toolbox for the maintenance of genome integrity. Nat Rev Mol Cell Biol. 2010;11(2):138-48.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, Issue.2
, pp. 138-148
-
-
Huen, M.S.1
Sy, S.M.2
Chen, J.3
-
7
-
-
77649131406
-
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
-
Moynahan ME, Jasin M. Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat Rev Mol Cell Biol. 2010;11(3):196-207.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, Issue.3
, pp. 196-207
-
-
Moynahan, M.E.1
Jasin, M.2
-
8
-
-
77953952646
-
BRCA1 and BRCA2: Breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair
-
O'Donovan PJ, Livingston DM. BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair. Carcinogenesis. 2010;31(6): 961-7.
-
(2010)
Carcinogenesis
, vol.31
, Issue.6
, pp. 961-967
-
-
O'donovan, P.J.1
Livingston, D.M.2
-
9
-
-
59149096408
-
The transcriptional corepressor CtBP: A foe of multiple tumor suppressors
-
Chinnadurai G. The transcriptional corepressor CtBP: a foe of multiple tumor suppressors. Cancer Res. 2009;69(3):731-4.
-
(2009)
Cancer Res
, vol.69
, Issue.3
, pp. 731-734
-
-
Chinnadurai, G.1
-
10
-
-
0037040581
-
Regulation of corepressor function by nuclear NADH
-
DOI 10.1126/science.1069300
-
Zhang Q, Piston DW, Goodman RH. Regulation of corepressor function by nuclear NADH. Science. 2002;295(5561):1895-7. (Pubitemid 34214127)
-
(2002)
Science
, vol.295
, Issue.5561
, pp. 1895-1897
-
-
Zhang, Q.1
Piston, D.W.2
Goodman, R.H.3
-
12
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
DOI 10.1126/science.1150034
-
Kolas NK et al. Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science. 2007;318(5856):1637-40. (Pubitemid 350233664)
-
(2007)
Science
, vol.318
, Issue.5856
, pp. 1637-1640
-
-
Kolas, N.K.1
Chapman, J.R.2
Nakada, S.3
Ylanko, J.4
Chahwan, R.5
Sweeney, F.D.6
Panier, S.7
Mendez, M.8
Wildenhain, J.9
Thomson, T.M.10
Pelletier, L.11
Jackson, S.P.12
Durocher, D.13
-
13
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
Huen MSY et al. RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell. 2007;131(5):901-14.
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 901-914
-
-
Msy, H.1
-
14
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil C et al. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell. 2009;136(3):435-46.
-
(2009)
Cell
, vol.136
, Issue.3
, pp. 435-446
-
-
Doil, C.1
-
15
-
-
72449163470
-
The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress
-
Morris JR et al. The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress. Nature. 2009;462 (7275):886-90.
-
(2009)
Nature
, vol.462
, Issue.7275
, pp. 886-890
-
-
Morris, J.R.1
-
16
-
-
72449175818
-
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
-
Galanty Y et al. Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature. 2009;462(7275):935-9.
-
(2009)
Nature
, vol.462
, Issue.7275
, pp. 935-939
-
-
Galanty, Y.1
-
17
-
-
14144253224
-
The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction
-
DOI 10.1038/nature03234
-
Yang H et al. The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction. Nature. 2005;433(7026):653-7. (Pubitemid 40283000)
-
(2005)
Nature
, vol.433
, Issue.7026
, pp. 653-657
-
-
Yang, H.1
Li, Q.2
Fan, J.3
Holloman, W.K.4
Pavletich, H.P.5
-
18
-
-
33744950933
-
Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide
-
San Filippo J et al. Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide. J Biol Chem. 2006;281(17):11649-57.
-
(2006)
J Biol Chem
, vol.281
, Issue.17
, pp. 11649-11657
-
-
San Filippo, J.1
-
19
-
-
77957975815
-
Purified human BRCA2 stimulates RAD51- mediated recombination
-
Jensen RB et al. Purified human BRCA2 stimulates RAD51- mediated recombination. Nature. 2010;467(7316):678-83.
-
(2010)
Nature
, vol.467
, Issue.7316
, pp. 678-683
-
-
Jensen, R.B.1
-
20
-
-
77957804604
-
The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA
-
Thorslund T et al. The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA. Nat Struct Mol Biol. 2010;17(10):1263-5.
-
(2010)
Nat Struct Mol Biol
, vol.17
, Issue.10
, pp. 1263-1265
-
-
Thorslund, T.1
-
21
-
-
77957804215
-
Human BRCA2 protein promotes RAD51 filament formation on RPA-covered singlestranded DNA
-
Liu J, Doty T, Gibson B, Heyer W. Human BRCA2 protein promotes RAD51 filament formation on RPA-covered singlestranded DNA. Nat Struct Mol Biol. 2010;17(10):1260-2.
-
(2010)
Nat Struct Mol Biol
, vol.17
, Issue.10
, pp. 1260-1262
-
-
Liu, J.1
Doty, T.2
Gibson, B.3
Heyer, W.4
-
22
-
-
75749096049
-
Screening for founder mutations in BRCA1 and BRCA2 in unselected Jewish women
-
Metcalfe KA et al. Screening for founder mutations in BRCA1 and BRCA2 in unselected Jewish women. J Clin Oncol. 2010;28 (3):387-91.
-
(2010)
J Clin Oncol
, vol.28
, Issue.3
, pp. 387-391
-
-
Metcalfe, K.A.1
-
23
-
-
0038744296
-
Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: A combined analysis of 22 studies
-
DOI 10.1086/375033
-
Antoniou A et al. Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies. Am J Hum Genet. 2003;72(5):1117-30. (Pubitemid 36530000)
-
(2003)
American Journal of Human Genetics
, vol.72
, Issue.5
, pp. 1117-1130
-
-
Antoniou, A.1
Pharoah, P.D.P.2
Narod, S.3
Risch, H.A.4
Eyfjord, J.E.5
Hopper, J.L.6
Loman, N.7
Olsson, H.8
Johannsson, O.9
Borg, A.10
Pasini, B.11
Radice, P.12
Manoukian, S.13
Eccles, D.M.14
Tang, N.15
Olah, E.16
Anton-Culver, H.17
Warner, E.18
Lubinski, J.19
Gronwald, J.20
Gorski, B.21
Tulinius, H.22
Thorlacius, S.23
Eerola, H.24
Nevanlinna, H.25
Syrjakoski, K.26
Kallioniemi, O.-P.27
Thompson, D.28
Evans, C.29
Peto, J.30
Lalloo, F.31
Evans, D.G.32
Easton, D.F.33
more..
-
24
-
-
33644865633
-
Familial clustering of site-specific cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population
-
DOI 10.1073/pnas.0511301103
-
Simchoni S et al. Familial clustering of site-specific cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population. ProcNatlAcad Sci USA. 2006;103(10):3770-4. (Pubitemid 43376630)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.10
, pp. 3770-3774
-
-
Simchoni, S.1
Friedman, E.2
Kaufman, B.3
Gershoni-Baruch, R.4
Orr-Urtreger, A.5
Kedar-Barnes, I.6
Shiri-Sverdlov, R.7
Dagan, E.8
Tsabari, S.9
Shohat, M.10
Catane, R.11
King, M.-C.12
Lahad, A.13
Levy-Lahad, E.14
-
25
-
-
38049171118
-
Variation of breast cancer risk among BRCA1/2 carriers
-
The Journal of the American Medical Association
-
Begg CB et al. Variation of breast cancer risk among BRCA1/2 carriers. JAMA: The Journal of the American Medical Association. 299(2):194-201.
-
JAMA
, vol.299
, Issue.2
, pp. 194-201
-
-
Begg, C.B.1
-
26
-
-
77957568513
-
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population
-
Antoniou AC et al. A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population. Nat Genet. 2010;42(10):885-92.
-
(2010)
Nat Genet
, vol.42
, Issue.10
, pp. 885-892
-
-
Antoniou, A.C.1
-
27
-
-
78649372135
-
Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers
-
Walker LC et al. Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers. Breast Cancer Res. 2010;12(6):R102.
-
(2010)
Breast Cancer Res
, vol.12
, Issue.6
-
-
Walker, L.C.1
-
28
-
-
78549237225
-
Association of the variants CASP8 D302H and CASP10 V410I with breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers
-
Engel C et al. Association of the variants CASP8 D302H and CASP10 V410I with breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. Cancer Epidemiol Biomark Prev. 2010;19(11):2859-68.
-
(2010)
Cancer Epidemiol Biomark Prev
, vol.19
, Issue.11
, pp. 2859-2868
-
-
Engel, C.1
-
29
-
-
41649097333
-
Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers
-
Antoniou AC et al. Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. Am J Hum Genet. 2008;82(4):937-48.
-
(2008)
Am J Hum Genet
, vol.82
, Issue.4
, pp. 937-948
-
-
Antoniou, A.C.1
-
30
-
-
71049194443
-
Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers
-
Antoniou AC et al. Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers. Hum Mol Genet. 2009;18(22):4442-56.
-
(2009)
Hum Mol Genet
, vol.18
, Issue.22
, pp. 4442-4456
-
-
Antoniou, A.C.1
-
31
-
-
36749002743
-
RAD51 135G→C modifies breast cancer risk among BRCA2 mutation carriers: Results from a combined analysis of 19 studies
-
DOI 10.1086/522611
-
Antoniou AC et al. RAD51 135G→C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies. Am J Hum Genet. 2007;81(6):1186-200. (Pubitemid 350211449)
-
(2007)
American Journal of Human Genetics
, vol.81
, Issue.6
, pp. 1186-1200
-
-
Antoniou, A.C.1
Sinilnikova, O.M.2
Simard, J.3
Leone, M.4
Dumont, M.5
Neuhausen, S.L.6
Struewing, J.P.7
Stoppa-Lyonnet, D.8
Barjhoux, L.9
Hughes, D.J.10
Coupier, I.11
Belotti, M.12
Lasset, C.13
Bonadona, V.14
Bignon, Y.-J.15
Rebbeck, T.R.16
Wagner, T.17
Lynch, H.T.18
Domchek, S.M.19
Nathanson, K.L.20
Garber, J.E.21
Weitzel, J.22
Narod, S.A.23
Tomlinson, G.24
Olopade, O.I.25
Godwin, A.26
Isaacs, C.27
Jakubowska, A.28
Lubinski, J.29
Gronwald, J.30
Gorski, B.31
Byrski, T.32
Huzarski, T.33
Peock, S.34
Cook, M.35
Baynes, C.36
Murray, A.37
Rogers, M.38
Daly, P.A.39
Dorkins, H.40
Schmutzler, R.K.41
Versmold, B.42
Engel, C.43
Meindl, A.44
Arnold, N.45
Niederacher, D.46
Deissler, H.47
Spurdle, A.B.48
Chen, X.49
Waddell, N.50
Cloonan, N.51
Kirchhoff, T.52
Offit, K.53
Friedman, E.54
Kaufmann, B.55
Laitman, Y.56
Galore, G.57
Rennert, G.58
Lejbkowicz, F.59
Raskin, L.60
Andrulis, I.L.61
Ilyushik, E.62
Ozcelik, H.63
Devilee, P.64
Vreeswijk, M.P.G.65
Greene, M.H.66
Prindiville, S.A.67
Osorio, A.68
Benitez, J.69
Zikan, M.70
Szabo, C.I.71
Kilpivaara, O.72
Nevanlinna, H.73
Hamann, U.74
Durocher, F.75
Arason, A.76
Couch, F.J.77
Easton, D.F.78
Chenevix-Trench, G.79
Chompret, A.80
Bressac-de-Paillerets, B.81
Byrde, V.82
Capoulade, C.83
Lenoir, G.84
Uhrhammer, N.85
Gauthier-Villars, M.86
De Pauw, A.87
Sinilnikova, O.88
more..
-
32
-
-
78649980806
-
Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: Implications for risk prediction
-
Antoniou AC et al. Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction. Cancer Res. 2010;70 (23):9742-54.
-
(2010)
Cancer Res
, vol.70
, Issue.23
, pp. 9742-9754
-
-
Antoniou, A.C.1
-
33
-
-
77954500544
-
Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers
-
Wang X et al. Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers. Hum Mol Genet. 2010;19(14):2886-97.
-
(2010)
Hum Mol Genet
, vol.19
, Issue.14
, pp. 2886-2897
-
-
Wang, X.1
-
34
-
-
78449242326
-
Common genetic variants and modification of penetrance of BRCA2-associated breast cancer
-
Gaudet MM et al. Common genetic variants and modification of penetrance of BRCA2-associated breast cancer. PLoS Genet. 2010;6(10):e1001183.
-
(2010)
PLoS Genet
, vol.6
, Issue.10
-
-
Gaudet, M.M.1
-
35
-
-
77949578084
-
Performance of common genetic variants in breast-cancer risk models
-
Wacholder S et al. Performance of common genetic variants in breast-cancer risk models. N Engl J Med. 2010;362(11):986-93.
-
(2010)
N Engl J Med
, vol.362
, Issue.11
, pp. 986-993
-
-
Wacholder, S.1
-
36
-
-
32944479344
-
Mammographic density and breast cancer risk in BRCA1 and BRCA2 mutation carriers
-
DOI 10.1158/0008-5472.CAN-05-3368
-
Mitchell G et al. Mammographic density and breast cancer risk in BRCA1 and BRCA2 mutation carriers. Cancer Res. 2006;66 (3):1866-72. (Pubitemid 43259974)
-
(2006)
Cancer Research
, vol.66
, Issue.3
, pp. 1866-1872
-
-
Mitchell, G.1
Antoniou, A.C.2
Warren, R.3
Peock, S.4
Brown, J.5
Davies, R.6
Mattison, J.7
Cook, M.8
Warsi, I.9
Evans, D.G.10
Eccles, D.11
Douglas, F.12
Paterson, J.13
Hodgson, S.14
Izatt, L.15
Cole, T.16
Burgess, L.17
Eeles, R.18
Easton, D.F.19
-
37
-
-
79952186049
-
Common variants in ZNF365 are associated with both mammographic density and breast cancer risk
-
Lindström S et al. Common variants in ZNF365 are associated with both mammographic density and breast cancer risk. Nat Genet. 2011;43(3):185-7.
-
(2011)
Nat Genet
, vol.43
, Issue.3
, pp. 185-187
-
-
Lindström, S.1
-
38
-
-
77952887426
-
Genome-wide association study identifies five new breast cancer susceptibility loci
-
Turnbull C et al. Genome-wide association study identifies five new breast cancer susceptibility loci. Nat Genet. 2010;42(6):504-7.
-
(2010)
Nat Genet
, vol.42
, Issue.6
, pp. 504-507
-
-
Turnbull, C.1
-
39
-
-
77349113419
-
Traffic control for BRCA1
-
Foulkes WD. Traffic control for BRCA1. N Engl J Med. 2010;362(8):755-6.
-
(2010)
N Engl J Med
, vol.362
, Issue.8
, pp. 755-756
-
-
Foulkes, W.D.1
-
40
-
-
77952600845
-
Susceptibility pathways in Fanconi's anemia and breast cancer
-
D'Andrea AD. Susceptibility pathways in Fanconi's anemia and breast cancer. N Engl J Med. 2010;362(20):1909-19.
-
(2010)
N Engl J Med
, vol.362
, Issue.20
, pp. 1909-1919
-
-
D'andrea, A.D.1
-
41
-
-
33746491583
-
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles
-
DOI 10.1038/ng1837, PII NG1837
-
Renwick A et al.ATMmutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles. Nat Genet. 2006;38(8):873-5. (Pubitemid 44141653)
-
(2006)
Nature Genetics
, vol.38
, Issue.8
, pp. 873-875
-
-
Renwick, A.1
Thompson, D.2
Seal, S.3
Kelly, P.4
Chagtai, T.5
Ahmed, M.6
North, B.7
Jayatilake, H.8
Barfoot, R.9
Spanova, K.10
McGuffog, L.11
Evans, D.G.12
Eccles, D.13
Easton, D.F.14
Stratton, M.R.15
Rahman, N.16
-
43
-
-
33847163983
-
A deletion in CHEK2 of 5,395 bp predisposes to breast cancer in Poland
-
DOI 10.1007/s10549-006-9320-y
-
Cybulski C et al. A deletion in CHEK2 of 5,395 bp predisposes to breast cancer in Poland. Breast Cancer Res Treat. 2007;102 (1):119-22. (Pubitemid 46294966)
-
(2007)
Breast Cancer Research and Treatment
, vol.102
, Issue.1
, pp. 119-122
-
-
Cybulski, C.1
Wokolorczyk, D.2
Huzarski, T.3
Byrski, T.4
Gronwald, J.5
Gorski, B.6
Debniak, T.7
Masojc, B.8
Jakubowska, A.9
Van De Wetering, T.10
Narod, S.A.11
Lubinski, J.12
-
44
-
-
22044445244
-
Association of two mutations in the CHEK2 gene with breast cancer
-
DOI 10.1002/ijc.21022
-
Bogdanova N et al. Association of two mutations in the CHEK2 gene with breast cancer. Int J Cancer. 2005;116(2):263-6. (Pubitemid 40967263)
-
(2005)
International Journal of Cancer
, vol.116
, Issue.2
, pp. 263-266
-
-
Bogdanova, N.1
Enssen-Dubrowinskaja, N.2
Feshchenko, S.3
Lazjuk, G.I.4
Rogov, Y.I.5
Dammann, O.6
Bremer, M.7
Karstens, J.H.8
Sohn, C.9
Dork, T.10
-
45
-
-
3843071233
-
CHEK2 variant I157T may be associated with increased breast cancer risk
-
DOI 10.1002/ijc.20299
-
Kilpivaara O et al. CHEK2 variant I157T may be associated with increased breast cancer risk. Int J Cancer. 2004;111(4):543-7. (Pubitemid 39045321)
-
(2004)
International Journal of Cancer
, vol.111
, Issue.4
, pp. 543-547
-
-
Kilpivaara, O.1
Vahteristo, P.2
Falck, J.3
Syrjakoski, K.4
Eerola, H.5
Easton, D.6
Bartkova, J.7
Lukas, J.8
Heikkila, P.9
Aittomaki, K.10
Holli, K.11
Blomqvist, C.12
Kallioniemi, O.-P.13
Bartek, J.14
Nevanlinna, H.15
-
46
-
-
14044272193
-
Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population
-
DOI 10.1093/hmg/ddi052
-
Shaag A et al. Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population. Hum Mol Genet. 2005;14(4):555-63. (Pubitemid 40277471)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.4
, pp. 555-563
-
-
Shaag, A.1
Walsh, T.2
Renbaum, P.3
Kirchhoff, T.4
Nafa, K.5
Shiovitz, S.6
Mandell, J.B.7
Welcsh, P.8
Lee, M.K.9
Ellis, N.10
Offit, K.11
Levy-Lahad, E.12
King, M.-C.13
-
47
-
-
34447551609
-
CHEK2 mutation and hereditary breast cancer
-
Bogdanova N et al. CHEK2 mutation and hereditary breast cancer. J Clin Oncol. 2007;25(19):e26.
-
(2007)
J Clin Oncol
, vol.25
, Issue.19
-
-
Bogdanova, N.1
-
48
-
-
33747884830
-
RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability
-
DOI 10.1093/carcin/bgi360, Special Issue on Chronic Pain
-
Heikkinen K et al. RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability. Carcinogenesis. 2006;27(8):1593-9. (Pubitemid 44288048)
-
(2006)
Carcinogenesis
, vol.27
, Issue.8
, pp. 1593-1599
-
-
Heikkinen, K.1
Rapakko, K.2
Karppinen, S.-M.3
Erkko, H.4
Knuutila, S.5
Lundan, T.6
Mannermaa, A.7
Borresen-Dale, A.-L.8
Borg, A.9
Barkardottir, R.B.10
Petrini, J.11
Winqvist, R.12
-
49
-
-
38349052915
-
Nijmegen Breakage Syndrome mutations and risk of breast cancer
-
Bogdanova N et al. Nijmegen Breakage Syndrome mutations and risk of breast cancer. Int J Cancer. 2008;122(4):802-6.
-
(2008)
Int J Cancer
, vol.122
, Issue.4
, pp. 802-806
-
-
Bogdanova, N.1
-
50
-
-
33745225487
-
Germline mutations 657del5 of the NBS1 gene contribute significantly to the incidence of breast cancer in Central Poland
-
Steffen J et al. Germline mutations 657del5 of the NBS1 gene contribute significantly to the incidence of breast cancer in Central Poland. Int J Cancer. 2006;119(2):472-5.
-
(2006)
Int J Cancer
, vol.119
, Issue.2
, pp. 472-475
-
-
Steffen, J.1
-
51
-
-
33750465216
-
Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles
-
DOI 10.1038/ng1902, PII NG1902
-
Seal S et al. Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles. Nat Genet. 2006;38(11):1239-41. (Pubitemid 44646283)
-
(2006)
Nature Genetics
, vol.38
, Issue.11
, pp. 1239-1241
-
-
Seal, S.1
Thompson, D.2
Renwick, A.3
Elliott, A.4
Kelly, P.5
Barfoot, R.6
Chagtai, T.7
Jayatilake, H.8
Ahmed, M.9
Spanova, K.10
North, B.11
McGuffog, L.12
Evans, D.G.13
Eccles, D.14
Easton, D.F.15
Stratton, M.R.16
Rahman, N.17
-
52
-
-
33846625493
-
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene
-
DOI 10.1038/ng1959, PII NG1959
-
Rahman N et al. PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene. Nat Genet. 2007;39(2):165-7. (Pubitemid 46184346)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 165-167
-
-
Rahman, N.1
Seal, S.2
Thompson, D.3
Kelly, P.4
Renwick, A.5
Elliott, A.6
Reid, S.7
Spanova, K.8
Barfoot, R.9
Chagtai, T.10
Jayatilake, H.11
McGuffog, L.12
Hanks, S.13
Evans, D.G.14
Eccles, D.15
Easton, D.F.16
Stratton, M.R.17
-
53
-
-
51649092869
-
Penetrance analysis of the PALB2 c.1592delT founder mutation
-
Erkko H et al. Penetrance analysis of the PALB2 c.1592delT founder mutation. Clin Cancer Res. 2008;14(14):4667-71.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.14
, pp. 4667-4671
-
-
Erkko, H.1
-
54
-
-
78650389153
-
A PALB2 mutation associated with high risk of breast cancer
-
Southey MC et al. A PALB2 mutation associated with high risk of breast cancer. Breast Cancer Res. 2010;12(6):R109.
-
(2010)
Breast Cancer Res
, vol.12
, Issue.6
-
-
Southey, M.C.1
-
55
-
-
0017238344
-
Malignant neoplasms in the families of patients with ataxia- telangiectasia
-
Swift M et al. Malignant neoplasms in the families of patients with ataxia-telangiectasia. Cancer Res. 1976;36(1):209-15.
-
(1976)
Cancer Res
, vol.36
, Issue.1
, pp. 209-215
-
-
Swift, M.1
-
56
-
-
70350490327
-
Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer
-
Tavtigian SV et al. Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer. Am J Hum Genet. 2009;85(4):427-46.
-
(2009)
Am J Hum Genet
, vol.85
, Issue.4
, pp. 427-446
-
-
Tavtigian, S.V.1
-
57
-
-
0033601346
-
Heterozygous germ line hCHK2 Mutations in Li-Fraumeni syndrome
-
Bell DW et al. Heterozygous germ line hCHK2 Mutations in Li-Fraumeni syndrome. Science. 1999;286(5449):2528-31.
-
(1999)
Science
, vol.286
, Issue.5449
, pp. 2528-1531
-
-
Bell, D.W.1
-
58
-
-
18544389716
-
Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations
-
Meijers-Heijboer H et al. Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nat Genet. 2002;31(1):55-9.
-
(2002)
Nat Genet
, vol.31
, Issue.1
, pp. 55-9
-
-
Meijers-Heijboer, H.1
-
59
-
-
8844220451
-
CHEK2 is a multiorgan cancer susceptibility gene
-
DOI 10.1086/426403
-
Cybulski C et al. CHEK2 is a multiorgan cancer susceptibility gene. Am J Hum Genet. 2004;75(6):1131-5. (Pubitemid 39532081)
-
(2004)
American Journal of Human Genetics
, vol.75
, Issue.6
, pp. 1131-1135
-
-
Cybulski, C.1
Gorski, B.2
Huzarski, T.3
Masojc, B.4
Mierzejewski, M.5
Debniak, T.6
Teodorczyk, U.7
Byrski, T.8
Gronwald, J.9
Matyjasik, J.10
Zlowocka, E.11
Lenner, M.12
Grabowska, E.13
Nej, K.14
Castaneda, J.15
Medrek, K.16
Szymanska, A.17
Szymanska, J.18
Kurzawski, G.19
Suchy, J.20
Oszurek, O.21
Witek, A.22
Narod, S.A.23
Lubinski, J.24
more..
-
60
-
-
33751202144
-
A large germline deletion in the Chek2 kinase gene is associated with an increased risk of prostate cancer
-
DOI 10.1136/jmg.2006.044974
-
Cybulski C et al. A large germline deletion in the Chek2 kinase gene is associated with an increased risk of prostate cancer. J Med Genet. 2006;43(11):863-6. (Pubitemid 44787112)
-
(2006)
Journal of Medical Genetics
, vol.43
, Issue.11
, pp. 863-866
-
-
Cybulski, C.1
Wokolorczyrk, D.2
Huzarski, T.3
Byrski, T.4
Gronwald, J.5
Gorski, B.6
Debniak, T.7
Masojc, B.8
Jakubowska, A.9
Gliniewicz, B.10
Sikorski, A.11
Stawicka, M.12
Godlewski, D.13
Kwias, Z.14
Antczak, A.15
Kraika, K.16
Lauer, W.17
Sosnowski, M.18
Sikorska-Radek, P.19
Bar, K.20
Klijer, R.21
Zdrojowy, R.22
Malkiewicz, B.23
Borkowski, A.24
Borkowski, T.25
Szwiec, M.26
Narod, S.A.27
Lubinski, J.28
more..
-
62
-
-
77951971957
-
The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells
-
Stolz A et al. The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells. Nat Cell Biol. 2010;12(5):492-9.
-
(2010)
Nat Cell Biol
, vol.12
, Issue.5
, pp. 492-499
-
-
Stolz, A.1
-
63
-
-
0035817764
-
Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway
-
DOI 10.1038/sj.onc.1204811
-
Falck J et al. Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway. Oncogene. 2001;20(39):5503-10. (Pubitemid 32889487)
-
(2001)
Oncogene
, vol.20
, Issue.39
, pp. 5503-5510
-
-
Falck, J.1
Lukas, C.2
Protopopova, M.3
Lukas, J.4
Selivanova, G.5
Bartek, J.6
-
64
-
-
0035848819
-
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
-
DOI 10.1038/35071124
-
Falck J et al. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature. 2001;410 (6830):842-7. (Pubitemid 32303786)
-
(2001)
Nature
, vol.410
, Issue.6830
, pp. 842-847
-
-
Falck, J.1
Mailand, N.2
Syljuasen, R.G.3
Bartek, J.4
Lukas, J.5
-
65
-
-
39149141409
-
CHEK2*1100delC genotyping for clinical assessment of breast cancer risk: Meta-analyses of 26,000 patient cases and 27,000 controls
-
DOI 10.1200/JCO.2007.12.5922
-
Weischer M et al. CHEK2*1100delC genotyping for clinical assessment of breast cancer risk: meta-analyses of 26,000 patient cases and 27,000 controls. J Clin Oncol. 2008;26(4):542-8. (Pubitemid 351264346)
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.4
, pp. 542-548
-
-
Weischer, M.1
Bojesen, S.E.2
Ellervik, C.3
Tybjaerg-Hansen, A.4
Nordestgaard, B.G.5
-
66
-
-
27544515629
-
Interaction between CHEK2*1100delC and other low-penetrance breast-cancer susceptibility genes: A familial study
-
DOI 10.1016/S0140-6736(05)67627-1, PII S0140673605676271
-
Johnson N et al. Interaction between CHEK2*1100delC and other low-penetrance breast-cancer susceptibility genes: a familial study. Lancet. 2005;366(9496):1554-7. (Pubitemid 41540113)
-
(2005)
Lancet
, vol.366
, Issue.9496
, pp. 1554-1557
-
-
Johnson, N.1
Fletcher, O.2
Naceur-Lombardelli, C.3
Dos Santos Silva, I.4
Ashworth, A.5
Peto, J.6
-
67
-
-
84860389647
-
Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: Results from a breast cancer family registry (CFR) casecontrol mutation screening study
-
Le Calvez-Kelm F et al. Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry (CFR) casecontrol mutation screening study. Breast Cancer Res. 2011;13(1): R6.
-
(2011)
Breast Cancer Res
, vol.13
, Issue.1
-
-
Le Calvez-Kelm, F.1
-
68
-
-
36949013395
-
ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks
-
DOI 10.1038/sj.onc.1210880, PII 1210880
-
Lavin MF. ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks. Oncogene. 2007;26 (56):7749-58. (Pubitemid 350242462)
-
(2007)
Oncogene
, vol.26
, Issue.56
, pp. 7749-7758
-
-
Lavin, M.F.1
-
69
-
-
52449114574
-
Ataxia-telangiectasia: From a rare disorder to a paradigm for cell signalling and cancer
-
Lavin MF. Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer. Nat Rev Mol Cell Biol. 2008;9(10):759-69.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.10
, pp. 759-769
-
-
Lavin, M.F.1
-
70
-
-
65149095154
-
Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder
-
Waltes R et al. Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder. Am J Hum Genet. 2009;84 (5):605-16.
-
(2009)
Am J Hum Genet
, vol.84
, Issue.5
, pp. 605-616
-
-
Waltes, R.1
-
71
-
-
56649086648
-
Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene
-
Bartkova J et al. Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene. Mol Oncol. 2008;2 (4):296-316.
-
(2008)
Mol Oncol
, vol.2
, Issue.4
, pp. 296-316
-
-
Bartkova, J.1
-
72
-
-
58149216582
-
Germline RAP80 mutations and susceptibility to breast cancer
-
Akbari MR et al. Germline RAP80 mutations and susceptibility to breast cancer. Breast Cancer Res Treat. 2009;113 (2):377-81.
-
(2009)
Breast Cancer Res Treat
, vol.113
, Issue.2
, pp. 377-381
-
-
Akbari, M.R.1
-
73
-
-
68949092118
-
Analysis of the genes coding for the BRCA1- interacting proteins, RAP80 and Abraxas (CCDC98), in highrisk, non-BRCA1/2, multiethnic breast cancer cases
-
Novak DJ, Sabbaghian N, Maillet P, Chappuis PO, Foulkes WD, Tischkowitz M. Analysis of the genes coding for the BRCA1- interacting proteins, RAP80 and Abraxas (CCDC98), in highrisk, non-BRCA1/2, multiethnic breast cancer cases. Breast Cancer Res Treat. 2009;117(2):453-9.
-
(2009)
Breast Cancer Res Treat
, vol.117
, Issue.2
, pp. 453-459
-
-
Novak, D.J.1
Sabbaghian, N.2
Maillet, P.3
Chappuis, P.O.4
Foulkes, W.D.5
Tischkowitz, M.6
-
74
-
-
58149268081
-
Evaluation of the BRCA1 interacting genes RAP80 and CCDC98 in familial breast cancer susceptibility
-
Osorio A et al. Evaluation of the BRCA1 interacting genes RAP80 and CCDC98 in familial breast cancer susceptibility. Breast Cancer Res Treat. 2009;113(2):371-6.
-
(2009)
Breast Cancer Res Treat
, vol.113
, Issue.2
, pp. 371-376
-
-
Osorio, A.1
-
75
-
-
67349155596
-
Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function
-
Nikkilä J et al. Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function. Oncogene. 2009;28(16):1843-52.
-
(2009)
Oncogene
, vol.28
, Issue.16
, pp. 1843-1852
-
-
Nikkilä, J.1
-
76
-
-
77957329128
-
PALB2/FANCN: Recombining cancer and Fanconi anemia
-
Tischkowitz M, Xia B. PALB2/FANCN: recombining cancer and Fanconi anemia. Cancer Res. 2010;70(19):7353-9.
-
(2010)
Cancer Res
, vol.70
, Issue.19
, pp. 7353-7359
-
-
Tischkowitz, M.1
Xia, B.2
-
77
-
-
18444362122
-
Biallelic inactivation of BRCA2 in Fanconi anemia
-
DOI 10.1126/science.1073834
-
Howlett NG et al. Biallelic inactivation of BRCA2 in Fanconi anemia. Science. 2002;297(5581):606-9. (Pubitemid 34815345)
-
(2002)
Science
, vol.297
, Issue.5581
, pp. 606-609
-
-
Howlett, N.G.1
Taniguchi, T.2
Olson, S.3
Cox, B.4
Waisfisz, Q.5
De Die-Smulders, C.6
Persky, N.7
Grompe, M.8
Joenje, H.9
Pals, G.10
Ikeda, H.11
Fox, E.A.12
D'Andrea, A.D.13
-
78
-
-
25144497571
-
The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia
-
DOI 10.1038/ng1624, PII NG1624
-
Levran O et al. The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia. Nat Genet. 2005;37(9):931-3. (Pubitemid 43086147)
-
(2005)
Nature Genetics
, vol.37
, Issue.9
, pp. 931-933
-
-
Levran, O.1
Attwooll, C.2
Henry, R.T.3
Milton, K.L.4
Neveling, K.5
Rio, P.6
Batish, S.D.7
Kalb, R.8
Velleuer, E.9
Barral, S.10
Ott, J.11
Petrini, J.12
Schindler, D.13
Hanenberg, H.14
Auerbach, A.D.15
-
79
-
-
25144457604
-
The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J
-
DOI 10.1038/ng1625, PII NG1625
-
Levitus M et al. The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J. Nat Genet. 2005;37 (9):934-5. (Pubitemid 43086148)
-
(2005)
Nature Genetics
, vol.37
, Issue.9
, pp. 934-935
-
-
Levitus, M.1
Waisfisz, Q.2
Godthelp, B.C.3
De Vries, Y.4
Hussain, S.5
Wiegant, W.W.6
Elghalbzouri-Maghrani, E.7
Steltenpool, J.8
Rooimans, M.A.9
Pals, G.10
Arwert, F.11
Mathew, C.G.12
Zdzienicka, M.Z.13
Hiom, K.14
De Winter, J.P.15
Joenje, H.16
-
80
-
-
20644461718
-
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function
-
DOI 10.1016/S0092-8674(01)00304-X
-
Cantor SB et al. BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell. 2001;105(1):149-60. (Pubitemid 32323924)
-
(2001)
Cell
, vol.105
, Issue.1
, pp. 149-160
-
-
Cantor, S.B.1
Bell, D.W.2
Ganesan, S.3
Kass, E.M.4
Drapkin, R.5
Grossman, S.6
Wahrer, D.C.R.7
Sgroi, D.C.8
Lane, W.S.9
Haber, D.A.10
Livingston, D.M.11
-
81
-
-
1442281478
-
The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations
-
DOI 10.1073/pnas.0308717101
-
Cantor S et al. The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations. Proc Natl Acad Sci USA. 2004;101(8):2357-62. (Pubitemid 38269316)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.8
, pp. 2357-2362
-
-
Cantor, S.1
Drapkin, R.2
Zhang, F.3
Lin, Y.4
Han, J.5
Pamidi, S.6
Livingston, D.M.7
-
82
-
-
33846569450
-
Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer
-
DOI 10.1038/ng1947, PII NG1947
-
Reid S et al. Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer. Nat Genet. 2007;39(2):162-4. (Pubitemid 46184345)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 162-164
-
-
Reid, S.1
Schindler, D.2
Hanenberg, H.3
Barker, K.4
Hanks, S.5
Kalb, R.6
Neveling, K.7
Kelly, P.8
Seal, S.9
Freund, M.10
Wurm, M.11
Batish, S.D.12
Lach, F.P.13
Yetgin, S.14
Neitzel, H.15
Ariffin, H.16
Tischkowitz, M.17
Mathew, C.G.18
Auerbach, A.D.19
Rahman, N.20
more..
-
83
-
-
33846601829
-
Fanconi anemia is associated with a defect in the BRCA2 partner PALB2
-
DOI 10.1038/ng1942, PII NG1942
-
Xia B et al. Fanconi anemia is associated with a defect in the BRCA2 partner PALB2. Nat Genet. 2007;39(2):159-61. (Pubitemid 46184344)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 159-161
-
-
Xia, B.1
Dorsman, J.C.2
Ameziane, N.3
De Vries, Y.4
Rooimans, M.A.5
Sheng, Q.6
Pals, G.7
Errami, A.8
Gluckman, E.9
Llera, J.10
Wang, W.11
Livingston, D.M.12
Joenje, H.13
De Winter, J.P.14
-
84
-
-
33847227378
-
A recurrent mutation in PALB2 in Finnish cancer families
-
DOI 10.1038/nature05609, PII NATURE05609
-
Erkko H et al. A recurrent mutation in PALB2 in Finnish cancer families. Nature. 2007;446(7133):316-9. (Pubitemid 46426155)
-
(2007)
Nature
, vol.446
, Issue.7133
, pp. 316-319
-
-
Erkko, H.1
Xia, B.2
Nikkila, J.3
Schleutker, J.4
Syrjakoski, K.5
Mannermaa, A.6
Kallioniemi, A.7
Pylkas, K.8
Karppinen, S.-M.9
Rapakko, K.10
Miron, A.11
Sheng, Q.12
Li, G.13
Mattila, H.14
Bell, D.W.15
Haber, D.A.16
Grip, M.17
Reiman, M.18
Jukkola-Vuorinen, A.19
Mustonen, A.20
Kere, J.21
Aaltonen, L.A.22
Kosma, V.-M.23
Kataja, V.24
Soini, Y.25
Drapkin, R.I.26
Livingston, D.M.27
Winqvist, R.28
more..
-
85
-
-
62549115236
-
PALB2 links BRCA1 and BRCA2 in the DNAdamage response
-
Zhang F et al. PALB2 links BRCA1 and BRCA2 in the DNAdamage response. Curr Biol. 2009;19(6):524-9.
-
(2009)
Curr Biol
, vol.19
, Issue.6
, pp. 524-529
-
-
Zhang, F.1
-
86
-
-
67651166786
-
PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2
-
Zhang F et al. PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2. Mol Cancer Res. 2009;7(7):1110-8.
-
(2009)
Mol Cancer Res
, vol.7
, Issue.7
, pp. 1110-1118
-
-
Zhang, F.1
-
87
-
-
33745200945
-
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2
-
Xia B et al. Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. Mol Cell. 2006;22(6):719-29.
-
(2006)
Mol Cell
, vol.22
, Issue.6
, pp. 719-729
-
-
Xia, B.1
-
88
-
-
77957761350
-
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2
-
Dray E et al. Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Nat Struct Mol Biol. 2010;17(10):1255-9.
-
(2010)
Nat Struct Mol Biol
, vol.17
, Issue.10
, pp. 1255-1259
-
-
Dray, E.1
-
89
-
-
34249857115
-
Analysis of PALB2/FANCN-associated breast cancer families
-
DOI 10.1073/pnas.0701724104
-
Tischkowitz M et al. Analysis of PALB2/FANCN-associated breast cancer families. Proc Natl Acad Sci USA. 2007;104(16):6788-93. (Pubitemid 47175579)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.16
, pp. 6788-6793
-
-
Tischkowitz, M.1
Xia, B.2
Sabbaghian, N.3
Reis-Filho, J.S.4
Hamel, N.5
Li, G.6
Van Beers, E.H.7
Li, L.8
Khalil, T.9
Quenneville, L.A.10
Omeroglu, A.11
Poll, A.12
Lepage, P.13
Wong, N.14
Nederlof, P.M.15
Ashworth, A.16
Tonin, P.N.17
Narod, S.A.18
Livingston, D.M.19
Foulkes, W.D.20
more..
-
90
-
-
64849092309
-
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene
-
Jones S et al. Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. Science. 2009;324 (5924):217.
-
(2009)
Science
, vol.324
, Issue.5924
, pp. 217
-
-
Jones, S.1
-
91
-
-
69349092943
-
Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer
-
Tischkowitz MD et al. Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer. Gastroenterology. 2009;137(3):1183-6.
-
(2009)
Gastroenterology
, vol.137
, Issue.3
, pp. 1183-1186
-
-
Tischkowitz, M.D.1
-
92
-
-
77951747926
-
Mutation of the RAD51C gene in a Fanconi anemialike disorder
-
Vaz F et al. Mutation of the RAD51C gene in a Fanconi anemialike disorder. Nat Genet. 2010;42(5):406-9.
-
(2010)
Nat Genet
, vol.42
, Issue.5
, pp. 406-409
-
-
Vaz, F.1
-
93
-
-
77951720395
-
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene
-
Meindl A et al. Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. Nat Genet. 2010;42(5):410-4.
-
(2010)
Nat Genet
, vol.42
, Issue.5
, pp. 410-414
-
-
Meindl, A.1
-
94
-
-
78650901418
-
RAD51C germline mutations in breast and ovarian cancer patients
-
Akbari MR et al. RAD51C germline mutations in breast and ovarian cancer patients. Breast Cancer Res. 2010;12(4):404.
-
(2010)
Breast Cancer Res
, vol.12
, Issue.4
, pp. 404
-
-
Akbari, M.R.1
-
95
-
-
78649319824
-
Screening RAD51C nucleotide alterations in patients with a family history of breast and ovarian cancer
-
Zheng Y et al. Screening RAD51C nucleotide alterations in patients with a family history of breast and ovarian cancer. Breast Cancer Res Treat. 2010;124(3):857-61.
-
(2010)
Breast Cancer Res Treat
, vol.124
, Issue.3
, pp. 857-861
-
-
Zheng, Y.1
-
96
-
-
79251632658
-
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype
-
Stoepker C et al. SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet. 2011;43(2):138-41.
-
(2011)
Nat Genet
, vol.43
, Issue.2
, pp. 138-141
-
-
Stoepker, C.1
-
97
-
-
79251611165
-
Mutations of the SLX4 gene in Fanconi anemia
-
Kim Y, Smogorzewska A, et al. Mutations of the SLX4 gene in Fanconi anemia. Nat Genet. 2011;43(2):142-6.
-
(2011)
Nat Genet
, vol.43
, Issue.2
, pp. 142-146
-
-
Kim, Y.1
Smogorzewska, A.2
-
98
-
-
79251624412
-
Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia
-
Crossan GP et al. Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia. Nat Genet. 2011;43(2):147-52.
-
(2011)
Nat Genet
, vol.43
, Issue.2
, pp. 147-152
-
-
Crossan, G.P.1
-
99
-
-
39149122546
-
Time to check CHEK2 in families with breast cancer?
-
DOI 10.1200/JCO.2007.13.8503
-
Offit K, Garber JE. Time to check CHEK2 in families with breast cancer? J Clin Oncol. 2008;26(4):519-20. (Pubitemid 351264342)
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.4
, pp. 519-520
-
-
Offit, K.1
Garber, J.E.2
-
100
-
-
0037033733
-
A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes
-
DOI 10.1038/sj.bjc.6600008
-
Antoniou AC et al. A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes. Br J Cancer. 2002;86(1):76-83. (Pubitemid 34146344)
-
(2002)
British Journal of Cancer
, vol.86
, Issue.1
, pp. 76-83
-
-
Antoniou, A.C.1
Pharoah, P.D.P.2
McMullan, G.3
Day, N.E.4
Stratton, M.R.5
Peto, J.6
Ponder, B.J.7
Easton, D.F.8
-
101
-
-
55749109888
-
Are the so-called low penetrance breast cancer genes, ATM, BRIP1, PALB2 and CHEK2, high risk for women with strong family histories?
-
Byrnes GB, Southey MC, Hopper JL. Are the so-called low penetrance breast cancer genes, ATM, BRIP1, PALB2 and CHEK2, high risk for women with strong family histories? Breast Cancer Res. 2008;10(3):208.
-
(2008)
Breast Cancer Res
, vol.10
, Issue.3
, pp. 208
-
-
Byrnes, G.B.1
Southey, M.C.2
Hopper, J.L.3
-
102
-
-
33847337318
-
A common coding variant in CASP8 is associated with breast cancer risk
-
DOI 10.1038/ng1981, PII NG1981
-
Cox A et al. A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet. 2007;39(3):352-8. (Pubitemid 46328496)
-
(2007)
Nature Genetics
, vol.39
, Issue.3
, pp. 352-358
-
-
Cox, A.1
Dunning, A.M.2
Garcia-Closas, M.3
Balasubramanian, S.4
Reed, M.W.R.5
Pooley, K.A.6
Scollen, S.7
Baynes, C.8
Ponder, B.A.J.9
Chanock, S.10
Lissowska, J.11
Brinton, L.12
Peplonska, B.13
Southey, M.C.14
Hopper, J.L.15
McCredie, M.R.E.16
Giles, G.G.17
Fletcher, O.18
Johnson, N.19
Dos Santos Silva, I.20
Gibson, L.21
Bojesen, S.E.22
Nordestgaard, B.G.23
Axelsson, C.K.24
Torres, D.25
Hamann, U.26
Justenhoven, C.27
Brauch, H.28
Chang-Claude, J.29
Kropp, S.30
Risch, A.31
Wang-Gohrke, S.32
Schurmann, P.33
Bogdanova, N.34
Dork, T.35
Fagerholm, R.36
Aaltonen, K.37
Blomqvist, C.38
Nevanlinna, H.39
Seal, S.40
Renwick, A.41
Stratton, M.R.42
Rahman, N.43
Sangrajrang, S.44
Hughes, D.45
Odefrey, F.46
Brennan, P.47
Spurdle, A.B.48
Chenevix-Trench, G.49
Beesley, J.50
Mannermaa, A.51
Hartikainen, J.52
Kataja, V.53
Kosma, V.-M.54
Couch, F.J.55
Olson, J.E.56
Goode, E.L.57
Broeks, A.58
Schmidt, M.K.59
Hogervorst, F.B.L.60
Veer, L.J.V.61
Kang, D.62
Yoo, K.-Y.63
Noh, D.-Y.64
Ahn, S.-H.65
Wedren, S.66
Hall, P.67
Low, Y.-L.68
Liu, J.69
Milne, R.L.70
Ribas, G.71
Gonzalez-Neira, A.72
Benitez, J.73
Sigurdson, A.J.74
Stredrick, D.L.75
Alexander, B.H.76
Struewing, J.P.77
Pharoah, P.D.P.78
Easton, D.F.79
more..
-
103
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
DOI 10.1038/nature05887, PII NATURE05887
-
Easton DF et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature. 2007;447 (7148):1087-93. (Pubitemid 47014426)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1087-1093
-
-
Easton, D.F.1
Pooley, K.A.2
Dunning, A.M.3
Pharoah, P.D.P.4
Thompson, D.5
Ballinger, D.G.6
Struewing, J.P.7
Morrison, J.8
Field, H.9
Luben, R.10
Wareham, N.11
Ahmed, S.12
Healey, C.S.13
Bowman, R.14
Meyer, K.B.15
Haiman, C.A.16
Kolonel, L.K.17
Henderson, B.E.18
Le Marchand, L.19
Brennan, P.20
Sangrajrang, S.21
Gaborieau, V.22
Odefrey, F.23
Shen, C.-Y.24
Wu, P.-E.25
Wang, H.-C.26
Eccles, D.27
Evans, D.G.28
Peto, J.29
Fletcher, O.30
Johnson, N.31
Seal, S.32
Stratton, M.R.33
Rahman, N.34
Chenevix-Trench, G.35
Bojesen, S.E.36
Nordestgaard, B.G.37
Axelsson, C.K.38
Garcia-Closas, M.39
Brinton, L.40
Chanock, S.41
Lissowska, J.42
Peplonska, B.43
Nevanlinna, H.44
Fagerholm, R.45
Eerola, H.46
Kang, D.47
Yoo, K.-Y.48
Noh, D.-Y.49
Ahn, S.-H.50
Hunter, D.J.51
Hankinson, S.E.52
Cox, D.G.53
Hall, P.54
Wedren, S.55
Liu, J.56
Low, Y.-L.57
Bogdanova, N.58
Schurmann, P.59
Dork, T.60
Tollenaar, R.A.E.M.61
Jacobi, C.E.62
Devilee, P.63
Klijn, J.G.M.64
Sigurdson, A.J.65
Doody, M.M.66
Alexander, B.H.67
Zhang, J.68
Cox, A.69
Brock, I.W.70
MacPherson, G.71
Reed, M.W.R.72
Couch, F.J.73
Goode, E.L.74
Olson, J.E.75
Meijers-Heijboer, H.76
Van Den Ouweland, A.77
Uitterlinden, A.78
Rivadeneira, F.79
Milne, R.L.80
Ribas, G.81
more..
-
104
-
-
67349158067
-
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)
-
Thomas G et al. A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet. 2009;41(5):579-84.
-
(2009)
Nat Genet
, vol.41
, Issue.5
, pp. 579-584
-
-
Thomas, G.1
-
105
-
-
61349163553
-
Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1
-
Zheng W et al. Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1. Nat Genet. 2009;41 (3):324-8.
-
(2009)
Nat Genet
, vol.41
, Issue.3
, pp. 324-328
-
-
Zheng, W.1
-
106
-
-
34250001297
-
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
-
DOI 10.1038/ng2075, PII NG2075
-
Hunter DJ et al. A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet. 2007;39(7):870-4. (Pubitemid 47014500)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 870-874
-
-
Hunter, D.J.1
Kraft, P.2
Jacobs, K.B.3
Cox, D.G.4
Yeager, M.5
Hankinson, S.E.6
Wacholder, S.7
Wang, Z.8
Welch, R.9
Hutchinson, A.10
Wang, J.11
Yu, K.12
Chatterjee, N.13
Orr, N.14
Willett, W.C.15
Colditz, G.A.16
Ziegler, R.G.17
Berg, C.D.18
Buys, S.S.19
McCarty, C.A.20
Feigelson, H.S.21
Calle, E.E.22
Thun, M.J.23
Hayes, R.B.24
Tucker, M.25
Gerhard, D.S.26
Fraumeni, J.F.27
Hoover, R.N.28
Thomas, G.29
Chanock, S.J.30
more..
-
107
-
-
67650825015
-
Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042
-
Milne RL et al. Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042. J Natl Cancer Inst. 2009;101(14):1012-8.
-
(2009)
J Natl Cancer Inst
, vol.101
, Issue.14
, pp. 1012-1018
-
-
Milne, R.L.1
-
108
-
-
34250002140
-
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer
-
DOI 10.1038/ng2064, PII NG2064
-
Stacey SN et al. Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet. 2007;39(7):865-9. (Pubitemid 47014497)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 865-869
-
-
Stacey, S.N.1
Manolescu, A.2
Sulem, P.3
Rafnar, T.4
Gudmundsson, J.5
Gudjonsson, S.A.6
Masson, G.7
Jakobsdottir, M.8
Thorlacius, S.9
Helgason, A.10
Aben, K.K.11
Strobbe, L.J.12
Albers-Akkers, M.T.13
Swinkels, D.W.14
Henderson, B.E.15
Kolonel, L.N.16
Le Marchand, L.17
Millastre, E.18
Andres, R.19
Godino, J.20
Garcia-Prats, M.D.21
Polo, E.22
Tres, A.23
Mouy, M.24
Saemundsdottir, J.25
Backman, V.M.26
Gudmundsson, L.27
Kristjansson, K.28
Bergthorsson, J.T.29
Kostic, J.30
Frigge, M.L.31
Geller, F.32
Gudbjartsson, D.33
Sigurdsson, H.34
Jonsdottir, T.35
Hrafnkelsson, J.36
Johannsson, J.37
Sveinsson, T.38
Myrdal, G.39
Grimsson, H.N.40
Jonsson, T.41
Von Holst, S.42
Werelius, B.43
Margolin, S.44
Lindblom, A.45
Mayordomo, J.I.46
Haiman, C.A.47
Kiemeney, L.A.48
Johannsson, O.T.49
Gulcher, J.R.50
Thorsteinsdottir, U.51
Kong, A.52
Stefansson, K.53
more..
-
109
-
-
44349087530
-
Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer
-
DOI 10.1038/ng.131, PII NG131
-
Stacey SN et al. Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet. 2008;40(6):703-6. (Pubitemid 351748861)
-
(2008)
Nature Genetics
, vol.40
, Issue.6
, pp. 703-706
-
-
Stacey, S.N.1
Manolescu, A.2
Sulem, P.3
Thorlacius, S.4
Gudjonsson, S.A.5
Jonsson, G.F.6
Jakobsdottir, M.7
Bergthorsson, J.T.8
Gudmundsson, J.9
Aben, K.K.10
Strobbe, L.J.11
Swinkels, D.W.12
Van Engelenburg, K.C.A.13
Henderson, B.E.14
Kolonel, L.N.15
Le Marchand, L.16
Millastre, E.17
Andres, R.18
Saez, B.19
Lambea, J.20
Godino, J.21
Polo, E.22
Tres, A.23
Picelli, S.24
Rantala, J.25
Margolin, S.26
Jonsson, T.27
Sigurdsson, H.28
Jonsdottir, T.29
Hrafnkelsson, J.30
Johannsson, J.31
Sveinsson, T.32
Myrdal, G.33
Grimsson, H.N.34
Sveinsdottir, S.G.35
Alexiusdottir, K.36
Saemundsdottir, J.37
Sigurdsson, A.38
Kostic, J.39
Gudmundsson, L.40
Kristjansson, K.41
Masson, G.42
Fackenthal, J.D.43
Adebamowo, C.44
Ogundiran, T.45
Olopade, O.I.46
Haiman, C.A.47
Lindblom, A.48
Mayordomo, J.I.49
Kiemeney, L.A.50
Gulcher, J.R.51
Rafnar, T.52
Thorsteinsdottir, U.53
Johannsson, O.T.54
Kong, A.55
Stefansson, K.56
more..
-
110
-
-
67349237973
-
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2
-
Ahmed S et al. Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet. 2009;41(5):585-90.
-
(2009)
Nat Genet
, vol.41
, Issue.5
, pp. 585-590
-
-
Ahmed, S.1
-
111
-
-
33846709493
-
Differential signal transduction of alternatively spliced FGFR2 variants expressed in human mammary epithelial cells
-
DOI 10.1002/jcp.20880
-
Moffa AB, Ethier SP. Differential signal transduction of alternatively spliced FGFR2 variants expressed in human mammary epithelial cells. J Cell Physiol. 2007;210(3):720-31. (Pubitemid 46188288)
-
(2007)
Journal of Cellular Physiology
, vol.210
, Issue.3
, pp. 720-731
-
-
Moffa, A.B.1
Ethier, S.P.2
-
112
-
-
70249128376
-
Functional enhancers at the gene-poor 8q24 cancer-linked locus
-
Jia L et al. Functional enhancers at the gene-poor 8q24 cancer-linked locus. PLoS Genet. 2009;5(8):e1000597.
-
(2009)
PLoS Genet
, vol.5
, Issue.8
-
-
Jia, L.1
-
113
-
-
77953098883
-
8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC
-
Ahmadiyeh N et al. 8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC. Proc Natl Acad Sci USA. 2010;107(21):9742-6.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.21
, pp. 9742-9746
-
-
Ahmadiyeh, N.1
-
114
-
-
65949099120
-
Genetic risk prediction-are we there yet?
-
Kraft P, Hunter DJ. Genetic risk prediction-are we there yet? N Engl J Med. 2009;360(17):1701-3.
-
(2009)
N Engl J Med
, vol.360
, Issue.17
, pp. 1701-1703
-
-
Kraft, P.1
Hunter, D.J.2
-
115
-
-
75749143502
-
Pathologic complete response rates in young women with BRCA1-positive breast cancers after neoadjuvant chemotherapy
-
Byrski T et al. Pathologic complete response rates in young women with BRCA1-positive breast cancers after neoadjuvant chemotherapy. J Clin Oncol. 2010;28(3):375-9.
-
(2010)
J Clin Oncol
, vol.28
, Issue.3
, pp. 375-379
-
-
Byrski, T.1
-
116
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
DOI 10.1038/nature03443
-
Bryant HE et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature. 2005;434(7035):913-7. (Pubitemid 40559005)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
Kyle, S.7
Meuth, M.8
Curtin, N.J.9
Helleday, T.10
-
117
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
DOI 10.1038/nature03445
-
Farmer H et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature. 2005;434 (7035):917-21. (Pubitemid 40559006)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 917-921
-
-
Farmer, H.1
McCabe, H.2
Lord, C.J.3
Tutt, A.H.J.4
Johnson, D.A.5
Richardson, T.B.6
Santarosa, M.7
Dillon, K.J.8
Hickson, I.9
Knights, C.10
Martin, N.M.B.11
Jackson, S.P.12
Smith, G.C.M.13
Ashworth, A.14
-
118
-
-
67650471685
-
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
Fong PC et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med. 2009;361 (2):123-34.
-
(2009)
N Engl J Med
, vol.361
, Issue.2
, pp. 123-134
-
-
Fong, P.C.1
-
119
-
-
77955019276
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: A proof-of-concept trial
-
Tutt A et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet. 2010;376(9737):235-44.
-
(2010)
Lancet
, vol.376
, Issue.9737
, pp. 235-244
-
-
Tutt, A.1
-
120
-
-
77955039099
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: A proof-of-concept trial
-
Audeh MW et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. Lancet. 2010;376(9737):245-51.
-
(2010)
Lancet
, vol.376
, Issue.9737
, pp. 245-251
-
-
Audeh, M.W.1
-
121
-
-
77957760669
-
Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination
-
Buisson R et al. Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination. Nat Struct Mol Biol. 2010;17(10):1247-54.
-
(2010)
Nat Struct Mol Biol
, vol.17
, Issue.10
, pp. 1247-1254
-
-
Buisson, R.1
-
122
-
-
22344443194
-
Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype
-
DOI 10.1158/1078-0432.CCR-04-2424
-
Lakhani SR et al. Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype. Clin Cancer Res. 2005;11(14):5175-80. (Pubitemid 41003703)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.14
, pp. 5175-5180
-
-
Lakhani, S.R.1
Reis-Filho, J.S.2
Fulford, L.3
Renault-Llorca, F.4
Van Vijver, M.D.5
Parry, S.6
Bishop, T.7
Benitez, J.8
Rivas, C.9
Bignon, Y.-J.10
Chang-Claude, J.11
Hamann, U.12
Cornelisse, C.J.13
Devilee, P.14
Beckmann, M.W.15
Nestle-Kramling, C.16
Daly, P.A.17
Haites, N.18
Varley, J.19
Lalloo, F.20
Evans, G.21
Maugard, C.22
Meijers-Heijboer, H.23
Klijn, J.G.M.24
Olah, E.25
Gusterson, B.A.26
Pilotti, S.27
Radice, P.28
Scherneck, S.29
Sobol, H.30
Jacquemier, J.31
Wagner, T.32
Peto, J.33
Stratton, M.R.34
McGuffog, L.35
Easton, D.F.36
more..
-
124
-
-
77951129391
-
BRCA1 expression in triple negative sporadic breast cancers
-
Galizia E et al. BRCA1 expression in triple negative sporadic breast cancers. Anal Quant Cytol Histol. 2010;32 (1):24-9.
-
(2010)
Anal Quant Cytol Histol
, vol.32
, Issue.1
, pp. 24-29
-
-
Galizia, E.1
-
125
-
-
33847022042
-
BRCA1 dysfunction in sporadic basal-like breast cancer
-
DOI 10.1038/sj.onc.1210014, PII 1210014
-
Turner NC et al. BRCA1 dysfunction in sporadic basal-like breast cancer. Oncogene. 2007;26(14):2126-32. (Pubitemid 46514749)
-
(2007)
Oncogene
, vol.26
, Issue.14
, pp. 2126-2132
-
-
Turner, N.C.1
Reis-Filho, J.S.2
Russell, A.M.3
Springall, R.J.4
Ryder, K.5
Steele, D.6
Savage, K.7
Gillett, C.E.8
Schmitt, F.C.9
Ashworth, A.10
Tutt, A.N.11
-
126
-
-
0037377764
-
Negative regulation of BRCA1 gene expression by HMGA1 proteins accounts for the reduced BRCA1 protein levels in sporadic breast carcinoma
-
DOI 10.1128/MCB.23.7.2225-2238.2003
-
Baldassarre G et al. Negative regulation of BRCA1 gene expression by HMGA1 proteins accounts for the reduced BRCA1 protein levels in sporadic breast carcinoma. Mol Cell Biol. 2003;23(7):2225-38. (Pubitemid 36351007)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.7
, pp. 2225-2238
-
-
Baldassarre, G.1
Battista, S.2
Belletti, B.3
Thakur, S.4
Pentimalli, F.5
Trapasso, F.6
Fedele, M.7
Pierantoni, G.8
Croce, C.M.9
Fusco, A.10
-
127
-
-
77949908546
-
Efficacy of neoadjuvant Cisplatin in triplenegative breast cancer
-
Silver DP et al. Efficacy of neoadjuvant Cisplatin in triplenegative breast cancer. J Clin Oncol. 2010;28(7):1145-53.
-
(2010)
J Clin Oncol
, vol.28
, Issue.7
, pp. 1145-1153
-
-
Silver, D.P.1
-
128
-
-
78751610848
-
Iniparib plus chemotherapy in metastatic triple-negative breast cancer
-
O'Shaughnessy J et al. Iniparib plus chemotherapy in metastatic triple-negative breast cancer. N Engl J Med. 2011;364(3):205-14.
-
(2011)
N Engl J Med
, vol.364
, Issue.3
, pp. 205-214
-
-
O'shaughnessy, J.1
-
129
-
-
79959625272
-
-
Sanofi aventis
-
Sanofi aventis. Sanofi-aventis-R & D Keys figures 2011; http://en.sanofi-aventis.com/research-innovation/rd-key-figures/rd-key-figures. asp
-
(2011)
Sanofi-aventis-R & D Keys Figures
-
-
|