COS-1 cells as packaging host for production of lentiviruses

Current Protocols in Cell Biology

Volumn , Issue SUPPL.50, 2011, Pages

  MacKenzie, Crystal J ^a   Shioda, Toshi ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

COS 1; HEK293T; Lentivirus; Packaging

Indexed keywords

BETA GALACTOSIDASE; VIRUS LARGE T ANTIGEN;

ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CELL STRAIN HEK293; EMBRYO; HUMAN; HUMAN CELL; LENTIVIRINAE; NONHUMAN; PRIORITY JOURNAL; SIMIAN VIRUS 40; VIRION; VIRUS REPLICATION;

CERCOPITHECUS AETHIOPS; LENTIVIRUS;

EID: 79959554917     PISSN: 19342500     EISSN: 19342616     Source Type: Journal    
DOI: 10.1002/0471143030.cb2607s50     Document Type: Article

References (51)

1. Azzouz, M. 2006. Gene therapy for ALS: Progress and prospects. Biochim. Biophys. Acta 1762:1122-1127.
2. Baekelandt, V., Eggermont, K., Michiels, M., Nuttin, B., and Debyser, Z. 2003. Optimized lentiviral vector production and purification procedure prevents immune response after trans-duction of mouse brain. Gene Ther. 10:1933-1940.
3. Blesch, A. 2004. Lentiviral and MLV based retroviral vectors for ex vivo and in vivo gene transfer. Methods 33:164-172.
4. Boutros, M. and Ahringer, J. 2008. The art and design of genetic screens: RNA interference. Nat. Rev. Genet. 9:554-566.
5. Burns, J.C., Friedmann, T., Driever, W., Burrascano, M., and Yee, J.K. 1993. Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc. Natl. Acad. Sci. U.S.A. 90:8033-8037.
6. Chang, L.J. and Zaiss, A.K. 2002. Lentiviral vectors: Preparation and use. Methods Mol. Med. 69:303-318.
7. Chapman, S.C., Lawson, A., Macarthur, W.C., Wiese, R.J., Loechel, R.H., Burgos-Trinidad, M., Wakefield, J.K., Ramabhadran, R., Mauch, T.J., and Schoenwolf, G.C. 2005. Ubiquitous GFP expression in transgenic chickens using a lentiviral vector. Development 132:935-940.
8. Charrier, S., Stockholm, D., Seye, K., Opolon, P., Taveau, M., Gross, D.A., Bucher-Laurent, S., Delenda, C., Vainchenker, W., Danos, O., and Galy, A. 2005. A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice. Gene Ther. 12:597-606.
9. Cockrell, A.S. and Kafri, T. 2007. Gene delivery by lentivirus vectors. Mol. Biotechnol. 36:184-204.
10. Coleman, J.E., Huentelman, M.J., Kasparov, S., Metcalfe, B.L., Paton, J.F., Katovich, M.J., Semple-Rowland, S.L., and Raizada, M.K. 2003. Efficient large-scale production and concentration of HIV-1-based lentiviral vectors for use in vivo. Physiol. Genomics 12:221-228.
11. Dann, C.T. 2007. New technology for an old favorite: Lentiviral transgenesis and RNAi in rats. Transgenic Res. 16:571-580.
12. Devitt, G., Thomas, M., Klibanov, A.M., Pfeiffer, T., and Bosch, V. 2007. Optimized protocol for the large scale production of HIV pseudovirions by transient transfection of HEK293T cells with linear fully deacylated polyethylenimine. J. Virol. Methods 146:298-304.
13. Echeverri, C.J., Beachy, P.A., Baum, B., Boutros, M., Buchholz, F., Chanda, S.K., Downward, J., Ellenberg, J., Fraser, A.G., and Hacohen, N. 2006. Minimizing the risk of reporting false pos itives in large-scale RNAi screens. Nat. Methods 3:777-779.
14. Follenzi, A., Santambrogio, L., and Annoni, A. 2007. Immune responses to lentiviral vectors. Curr. Gene Ther. 7:306-315.
15. Galy, A., Roncarolo, M.G., and Thrasher, A.J. 2008. Development of lentiviral gene therapy for Wiskott Aldrich syndrome. Expert Opin. Biol. Ther. 8:181-190.
16. Geraerts, M., Michiels, M., Baekelandt, V., Debyser, Z., and Gijsbers, R. 2005. Upscaling of lentiviral vector production by tangential flow filtration. J. Gene Med. 7:1299-1310.
17. Kahl, C.A., Marsh, J., Fyffe, J., Sanders, D.A., and Cornetta, K. 2004. Human immunodeficiency virus type 1-derived lentivirus vectors pseudo-typed with envelope glycoproteins derived from Ross River virus and Semliki Forest virus. J. Virol. 78:1421-1430.
18. Koldej, R., Cmielewski, P., Stocker, A., Parsons, D.W., and Anson, D.S. 2005. Optimization of a multipartite human immunodeficiency virus based vector system: Control of virus infectivity and large-scale production. J. Gene Med. 7:1390-1399.
19. Kolegraff, K., Bostik, P., and Ansari, A.A. 2006. Characterization and role of lentivirus-associated host proteins. Exp. Biol. Med. 231:252-263.
20. Lillico, S.G., Sherman, A., McGrew, M.J., Robertson, C.D., Smith, J., Haslam, C., Barnard, P., Radcliffe, P.A., Mitrophanous, K.A., Elliot, E.A., and Sang, H.M. 2007. Oviduct-specific expression of two therapeutic proteins in transgenic hens. Proc. Natl. Acad. Sci. U.S.A. 104:1771-1776.
21. Luno, A.R. 2006. Ethical reflections on vaccines using cells from aborted fetuses. Natl. Cathol. Bioeth. Q. 6:453-459.
22. Lyon, A.R., Sato, M., Hajjar, R.J., Samulski, R.J., and Harding, S.E. 2008. Gene therapy: Targeting the myocardium. Heart 94:89-99.
23. Mandel, R.J., Burger, C., and Snyder, R.O. 2008. Viral vectors for in vivo gene transfer in Parkinson's disease: Properties and clinical grade production. Exp. Neurol. 209:58-71.
24. McGrew, M.J., Sherman, A., Ellard, F.M., Lillico, S.G., Gilhooley, H.J., Kingsman, A.J., Mitrophanous, K.A., and Sang, H. 2004. Efficient production of germline transgenic chickens using lentiviral vectors. EMBO Rep. 5:728-733.
25. Mitta, B., Rimann, M., and Fussenegger, M. 2005. Detailed design and comparative analysis of protocols for optimized production of high-performance HIV-1-derived lentiviral particles. Metab. Eng. 7:426-436.
26. Moffat, J. and Sabatini, D.M. 2006. Building mammalian signalling pathways with RNAi screens. Nat. Rev. Mol. Cell Biol. 7:177-187.
27. Moffat, J., Grueneberg, D.A., Yang, X., Kim, S.Y., Kloepfer, A.M., Hinkle, G., Piqani, B., Eisenhaure, T.M., Luo, B., and Grenier, J.K. 2006. A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell 124:1283-1298.
28. Mortellaro, A., Hernandez, R.J., Guerrini, M.M., Carlucci, F., Tabucchi, A., Ponzoni, M., Sanvito, F., Doglioni, C., Di Serio, C., and Biasco, L. 2006. Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects. Blood 108:2979-2988.
29. Naldini, L., Blomer, U., Gage, F.H., Trono, D., and Verma, I.M. 1996a. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc. Natl. Acad. Sci. U.S.A. 93:11382-11388.
30. Naldini, L., Blomer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F.H., Verma, I.M., and Trono, D. 1996b. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272:263-267.
31. Neschadim, A., McCart, J.A., Keating, A., and Medin, J.A. 2007. A roadmap to safe, efficient, and stable lentivirus-mediated gene therapy with hematopoietic cell transplantation. Biol. Blood Marrow Transplant 13:1407-1416.
32. Nixon, A.J., Goodrich, L.R., Scimeca, M.S., Witte, T.H., Schnabel, L.V., Watts, A.E., and Robbins, P.D. 2007. Gene therapy in musculoskeletal repair. Ann. N.Y. Acad. Sci. 1117:310-327.
33. Paddison, P.J., Silva, J.M., Conklin, D.S., Schlabach, M., Li, M., Aruleba, S., Balija, V., O'Shaughnessy, A., Gnoj, L., and Scobie, K. 2004. A resource for large-scale RNA-interference-based screens in mammals. Nature 428:427-431.
34. Park, F. 2007. Lentiviral vectors: Are they the future of animal transgenesis? Physiol. Genomics 31:159-173.
35. Pontifical Academy for Life. 2006. Moral reflections on vaccines prepared from cells derived from aborted human fetuses. Natl. Cathol. Bioeth. Q. 6:541-537.
36. Pruss, A.R. 2004. Cooperation with past evil and use of cell-lines derived from aborted fetuses. Linacre Q. 71:335-350.
37. Root, D.E., Hacohen, N., Hahn, W.C., Lander, E.S., and Sabatini, D.M. 2006. Genome-scale loss- of-function screening with a lentiviral RNAi library. Nat. Methods 3:715-719.
38. Scherr, M., Battmer, K., Eder, M., Schule, S., Hohenberg, H., Ganser, A., Grez, M., and Blomer, U. 2002. Efficient gene transfer into the CNS by lentiviral vectors purified by anion exchange chromatography. Gene Ther. 9:1708-1714.
39. Scott, B.B. and Lois, C. 2006. Generation of transgenic birds with replication-deficient lentiviruses. Nat. Protoc. 1:1406-1411.
40. Segura, M.M., Kamen, A., and Garnier, A. 2006. Downstream processing of oncoretroviral and lentiviral gene therapy vectors. Biotechnol. Adv. 24:321-337.
41. Segura, M.M., Garnier, A., Durocher, Y., Coelho, H., and Kamen, A. 2007. Production of lentiviral vectors by large-scale transient transfection of suspension cultures and affinity chromatography purification. Biotechnol. Bioeng. 98:789-799.
42. Sena-Esteves, M., Tebbets, J.C., Steffens, S., Crombleholme, T., and Flake, A.W. 2004. Optimized large-scale production of high titer lentivirus vector pseudotypes. J. Virol. Methods 122:131-139.
43. Silva, J.M., Li, M.Z., Chang, K., Ge, W., Golding, M.C., Rickles, R.J., Siolas, D., Hu, G., Paddison, P.J., and Schlabach, M.R. 2005. Second-generation shRNA libraries covering the mouse and human genomes. Nat. Genet. 37:1281-1288.
44. Smith, S.L. and Shioda, T. 2009. Advantages of COS-1 monkey kidney epithelial cells as packaging host for small-volume production of high-quality recombinant lentiviruses. J. Virol. Methods 157:47-54.
45. Tonini, T., Claudio, P.P., Giordano, A., and Romano, G. 2004. Transient production of retroviral- and lentiviral-based vectors for the transduction of mammalian cells. Methods Mol. Biol. 285:141-148.
46. Wong, A. 2006. The ethics of HEK 293. Natl. Cathol. Bioeth. Q. 6:473-495.
47. Yamada, K., McCarty, D.M., Madden, V.J., and Walsh, C.E. 2003. Lentivirus vector purification using anion exchange HPLC leads to improved gene transfer. Biotechniques 34:1074-1080.
48. Yamamoto, T. and Tsunetsugu-Yokota, Y. 2008. Prospects for the therapeutic application of lentivirus-based gene therapy to HIV-1 infection. Curr. Gene Ther. 8:1-8.
49. Zaia, J.A. 2007. The status of gene vectors for the treatment of diabetes. Cell Biochem. Biophys. 48:183-190.
50. Zufferey, R., Nagy, D., Mandel, R.J., Naldini, L., and Trono, D. 1997. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat. Biotechnol. 15:871-875.
51. Zufferey, R., Dull, T., Mandel, R.J., Bukovsky, A., Quiroz, D., Naldini, L., and Trono, D. 1998. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J. Virol. 72:9873-9880.