Efficient gene transfer into the CNS by lentiviral vectors purified by anion exchange chromatography

Gene Therapy

Volumn 9, Issue 24, 2002, Pages 1708-1714

  Scherr, M ^a   Battmer, K ^a   Eder, M ^a   Schule S ^b   Hohenberg, H ^c   Ganser, A ^a   Grez, M ^b   Blomer U ^a,d  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b INSTITUTE FOR TUMOR BIOLOGY AND EXPERIMENTAL THERAPY   (Germany)

^c LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^d UNIVERSITY OF KIEL   (Germany)

Author keywords

Anion exchange chromatography; CNS; Concentration; In vivo transduction; Lentiviral Vectors

Indexed keywords

COMPLEMENTARY DNA; LENTIVIRUS VECTOR; SODIUM CHLORIDE; VIRUS GLYCOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANION EXCHANGE CHROMATOGRAPHY; BRAIN TISSUE; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA MODIFICATION; FEMALE; GENE EXPRESSION; GENE TRANSFER; GLIA CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; RATING SCALE; REVIEW; STEREOTAXIS; TARGET CELL; TISSUE INJURY; TRANSGENE; ULTRAFILTRATION; VIRAL GENE DELIVERY SYSTEM; VIRUS CAPSID; VIRUS PARTICLE; VIRUS PURIFICATION;

ANIMALS; BRAIN; CELLS, CULTURED; CHROMATOGRAPHY, ION EXCHANGE; FEMALE; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; LENTIVIRUS; LUMINESCENT PROTEINS; NEUROGLIA; NEURONS; RATS; RATS, INBRED F344; TRANSDUCTION, GENETIC;

ANIMALIA; LENTIVIRUS; MIRIDAE; RNA VIRUSES;

EID: 0036957811     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301848     Document Type: Review

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