-
2
-
-
0027416970
-
Immunomodulation therapy for squamous cell carcinoma of the head and neck
-
Cortesina G, De Stefani A, Sacchi M, Rosso S, Galeazzi E. Immunomodulation therapy for squamous cell carcinoma of the head and neck. Head Neck, 1993; 15:266-70.
-
(1993)
Head Neck
, vol.15
, pp. 266-270
-
-
Cortesina, G.1
de Stefani, A.2
Sacchi, M.3
Rosso, S.4
Galeazzi, E.5
-
4
-
-
0027239503
-
Antitumor and antimetastatic activity of interleukin 12 against murine tumors
-
Brunda MJ, Luistro L, Warrier RR, Wright RB, Hubbard BR, Murphy M, et al. Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J Exp Med, 1993; 178:1223-30.
-
(1993)
J Exp Med
, vol.178
, pp. 1223-1230
-
-
Brunda, M.J.1
Luistro, L.2
Warrier, R.R.3
Wright, R.B.4
Hubbard, B.R.5
Murphy, M.6
-
5
-
-
0034763143
-
Regulation of interleukin-12 production in antigen-presenting cells
-
Ma X, Trinchieri G. Regulation of interleukin-12 production in antigen-presenting cells. Adv Immunol, 2001; 79:55-92.
-
(2001)
Adv Immunol
, vol.79
, pp. 55-92
-
-
Ma, X.1
Trinchieri, G.2
-
6
-
-
0030051658
-
Regulation of murine macrophage IL-12 production. Activation of macrophages in vivo, restimulation in vitro, and modulation by other cytokines
-
Skeen MJ, Miller MA, Shinnick TM, Ziegler HK. Regulation of murine macrophage IL-12 production. Activation of macrophages in vivo, restimulation in vitro, and modulation by other cytokines. J Immunol, 1996; 15:1196-206.
-
(1996)
J Immunol
, vol.15
, pp. 1196-1206
-
-
Skeen, M.J.1
Miller, M.A.2
Shinnick, T.M.3
Ziegler, H.K.4
-
7
-
-
0030051657
-
Endogenous IL-12 is necessary for rejection of P815 tumor variants in vivo
-
Fallarino F, Uyttenhove C, Boon T, Gajewski TF. Endogenous IL-12 is necessary for rejection of P815 tumor variants in vivo. J Immunol, 1996; 156:1095- 100.
-
(1996)
J Immunol
, vol.156
, pp. 1095-1100
-
-
Fallarino, F.1
Uyttenhove, C.2
Boon, T.3
Gajewski, T.F.4
-
8
-
-
0032748338
-
Interleukin-12 as an adjuvant for cancer immunotherapy
-
Rodolfo M, Colombo MP. Interleukin-12 as an adjuvant for cancer immunotherapy. Methods, 1999; 1:114-20.
-
(1999)
Methods
, vol.1
, pp. 114-120
-
-
Rodolfo, M.1
Colombo, M.P.2
-
9
-
-
0028944328
-
Influence of interleukin 12 on p53 peptide vaccination against established Meth A sarcoma
-
Noguchi Y, Richards EC, Chen YT, Old LJ. Influence of interleukin 12 on p53 peptide vaccination against established Meth A sarcoma. Proc Natl Acad Sci U S A, 1995; 92:2219-23.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 2219-2223
-
-
Noguchi, Y.1
Richards, E.C.2
Chen, Y.T.3
Old, L.J.4
-
10
-
-
0036005890
-
Interleukin-12 in antitumor immunity and immunotherapy
-
Colombo MP, Trinchieri G. Interleukin-12 in antitumor immunity and immunotherapy. Cytokine Growth Factor Rev, 2002; 13:155-68.
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 155-168
-
-
Colombo, M.P.1
Trinchieri, G.2
-
11
-
-
59349113775
-
Angiostatin anti-angiogenesis requires IL-12: The innate immune system as a key target
-
Albini A, Brigati C, Ventura A, Lorusso G, Pinter M, Morini M, et al. Angiostatin anti-angiogenesis requires IL-12: the innate immune system as a key target. J Transl Med, 2009; 7:5.
-
(2009)
J Transl Med
, vol.7
, pp. 5
-
-
Albini, A.1
Brigati, C.2
Ventura, A.3
Lorusso, G.4
Pinter, M.5
Morini, M.6
-
12
-
-
33750572453
-
Anti-angiogenic effects of interleukin-12 delivered by a novel hyperthermia induced gene construct
-
Siddiqui F, Ehrhart EJ, Charles B, Chubb L, Li CY, Zhang X, et al. Anti-angiogenic effects of interleukin-12 delivered by a novel hyperthermia induced gene construct. Int J Hyperthermia, 2006; 22:587-606.
-
(2006)
Int J Hyperthermia
, vol.22
, pp. 587-606
-
-
Siddiqui, F.1
Ehrhart, E.J.2
Charles, B.3
Chubb, L.4
Li, C.Y.5
Zhang, X.6
-
13
-
-
0028897739
-
Inhibition of angiogenesis in vivo by interleukin 12
-
Voest EE, Kenyon BM, O'Reilly MS, Truitt G, D'Amato RJ, Folkman J. Inhibition of angiogenesis in vivo by interleukin 12. J Natl Cancer Inst, 1995; 8:581-6.
-
(1995)
J Natl Cancer Inst
, vol.8
, pp. 581-586
-
-
Voest, E.E.1
Kenyon, B.M.2
O'Reilly, M.S.3
Truitt, G.4
D'amato, R.J.5
Folkman, J.6
-
14
-
-
0033052143
-
The toxicology of interleukin-12: A review
-
Car BD, Eng VM, Lipman JM, Anderson TD. The toxicology of interleukin-12: a review. Toxicol Pathol, 1999; 27:58-63.
-
(1999)
Toxicol Pathol
, vol.27
, pp. 58-63
-
-
Car, B.D.1
Eng, V.M.2
Lipman, J.M.3
Anderson, T.D.4
-
15
-
-
0037458828
-
Tumor regression by repeated intratumoral delivery of water soluble lipopolymers/p2CMVmIL-12 complexes
-
Yockman JW, Maheshwari A, Han SO, Kim SW. Tumor regression by repeated intratumoral delivery of water soluble lipopolymers/p2CMVmIL-12 complexes. J Control Release, 2003; 87:177-86.
-
(2003)
J Control Release
, vol.87
, pp. 177-186
-
-
Yockman, J.W.1
Maheshwari, A.2
Han, S.O.3
Kim, S.W.4
-
16
-
-
0029681849
-
Injection of complementary DNA encoding interleukin-12 inhibits tumor establishment at a distant site in a murine renal carcinoma model
-
Tan J, Newton CA, Djeu JY, Gutsch DE, Chang AE, Yang NS, et al. Injection of complementary DNA encoding interleukin-12 inhibits tumor establishment at a distant site in a murine renal carcinoma model. Cancer Res, 1996; 56:3399-403.
-
(1996)
Cancer Res
, vol.56
, pp. 3399-3403
-
-
Tan, J.1
Newton, C.A.2
Djeu, J.Y.3
Gutsch, D.E.4
Chang, A.E.5
Yang, N.S.6
-
17
-
-
0036535679
-
Non-viral gene delivery systems
-
Davis ME. Non-viral gene delivery systems. Curr Opin Biotechnol, 2002; 13:128-31.
-
(2002)
Curr Opin Biotechnol
, vol.13
, pp. 128-131
-
-
Davis, M.E.1
-
18
-
-
0037294039
-
Non-viral and hybrid vectors in human gene therapy: An update
-
Schmidt-Wolf GD, Schmidt-Wolf IG. Non-viral and hybrid vectors in human gene therapy: an update. Trends Mol Med, 2003; 9:67-72.
-
(2003)
Trends Mol Med
, vol.9
, pp. 67-72
-
-
Schmidt-Wolf, G.D.1
Schmidt-Wolf, I.G.2
-
19
-
-
1842684996
-
Nanomedicines for overcoming biological barriers
-
Alonso MJ. Nanomedicines for overcoming biological barriers. Biomed Pharmacother, 2004; 58:168-72.
-
(2004)
Biomed Pharmacother
, vol.58
, pp. 168-172
-
-
Alonso, M.J.1
-
20
-
-
69749099777
-
Nanoparticulate systems for polynucleotide delivery
-
Basarkar A, Singh J. Nanoparticulate systems for polynucleotide delivery. Int J Nanomedicine, 2007; 2:353-60.
-
(2007)
Int J Nanomedicine
, vol.2
, pp. 353-360
-
-
Basarkar, A.1
Singh, J.2
-
21
-
-
0004078385
-
-
Elsevier Inc, California, USA
-
Huang, L.; Hung MCH.; Wagner, E., Non-viral Vectors for Gene Therapy. Elsevier Inc, California, USA, 2005.
-
(2005)
Non-viral Vectors for Gene Therapy
-
-
Huang, L.1
Hung, M.C.H.2
Wagner, E.3
-
22
-
-
0037130565
-
Chitosan and its derivatives--a promising non-viral vector for gene transfection
-
Guang Liu W, De Yao K. Chitosan and its derivatives--a promising non-viral vector for gene transfection. J Control Release, 2002; 83:1-11.
-
(2002)
J Control Release
, vol.83
, pp. 1-11
-
-
Guang, L.W.1
de Yao, K.2
-
23
-
-
43049125824
-
Chitosan-mediated orally delivered nucleic acids: A gutful of gene therapy
-
Dass CR, Choong PF. Chitosan-mediated orally delivered nucleic acids: a gutful of gene therapy. J Drug Target, 2008;16:257-61.
-
(2008)
J Drug Target
, vol.16
, pp. 257-261
-
-
Dass, C.R.1
Choong, P.F.2
-
24
-
-
85047685252
-
Cancer, chitosan nanoparticles and catalytic nucleic acids
-
Tan ML, Choong PF, Dass CR. Cancer, chitosan nanoparticles and catalytic nucleic acids. J Pharm Pharmacol, 2009; 61:3-12.
-
(2009)
J Pharm Pharmacol
, vol.61
, pp. 3-12
-
-
Tan, M.L.1
Choong, P.F.2
Dass, C.R.3
-
25
-
-
77249111686
-
The safety of chitosan as a pharmaceutical excipient
-
Baldrick P. The safety of chitosan as a pharmaceutical excipient. Regul Toxicol Pharmacol. Apr;56(3):290-9.
-
Regul Toxicol Pharmacol
, vol.56
, Issue.3
, pp. 290-299
-
-
Baldrick, P.1
-
26
-
-
61349123258
-
Nucleic acid delivery with chitosan and its derivatives
-
Lai WF, Lin MC. Nucleic acid delivery with chitosan and its derivatives. J Control Release, 2009; 134:158-68.
-
(2009)
J Control Release
, vol.134
, pp. 158-168
-
-
Lai, W.F.1
Lin, M.C.2
-
27
-
-
0035813684
-
Chitosans for gene delivery
-
Borchard G. Chitosans for gene delivery. Adv Drug Deliv Rev, 2001; 52:145-50.
-
(2001)
Adv Drug Deliv Rev
, vol.52
, pp. 145-150
-
-
Borchard, G.1
-
28
-
-
19444375104
-
DNA-based therapeutics and DNA delivery systems: A comprehensive review
-
Patil SD, Rhodes DG, Burgess DJ. DNA-based therapeutics and DNA delivery systems: a comprehensive review. AAPS J, 2005; 7:E61-77.
-
(2005)
AAPS J
, vol.7
-
-
Patil, S.D.1
Rhodes, D.G.2
Burgess, D.J.3
-
29
-
-
0028625325
-
Construction and characterization of retroviral vectors expressing biologically active human interleukin-12
-
Zitvogel L, Tahara H, Cai Q, Storkus WJ, Muller G, Wolf SF, et al. Construction and characterization of retroviral vectors expressing biologically active human interleukin-12. Hum Gene Ther, 1994; 5:1493-506.
-
(1994)
Hum Gene Ther
, vol.5
, pp. 1493-1506
-
-
Zitvogel, L.1
Tahara, H.2
Cai, Q.3
Storkus, W.J.4
Muller, G.5
Wolf, S.F.6
-
30
-
-
0028840525
-
High cytokine production and effective antitumor activity of a recombinant vaccinia virus encoding murine interleukin 12
-
Meko JB, Yim JH, Tsung K, Norton JA. High cytokine production and effective antitumor activity of a recombinant vaccinia virus encoding murine interleukin 12. Cancer Res, 1995; 55:4765-70.
-
(1995)
Cancer Res
, vol.55
, pp. 4765-4770
-
-
Meko, J.B.1
Yim, J.H.2
Tsung, K.3
Norton, J.A.4
-
31
-
-
0031178963
-
Eradication of murine bladder carcinoma by intratumor injection of a bicistronic adenoviral vector carrying cDNAs for the IL-12 heterodimer and its inhibition by the IL-12 p40 subunit homodimer
-
Chen L, Chen D, Block E, O'Donnell M, Kufe DW, Clinton SK. Eradication of murine bladder carcinoma by intratumor injection of a bicistronic adenoviral vector carrying cDNAs for the IL-12 heterodimer and its inhibition by the IL-12 p40 subunit homodimer. J Immunol, 1997; 159:351-9.
-
(1997)
J Immunol
, vol.159
, pp. 351-359
-
-
Chen, L.1
Chen, D.2
Block, E.3
O'Donnell, M.4
Kufe, D.W.5
Clinton, S.K.6
-
32
-
-
34047252681
-
Evaluation of the antitumoral effect mediated by IL-12 and HSV-tk genes when delivered by a novel lipid-based system
-
Faneca H, Cabrita AS, Simoes S, Pedroso de Lima MC. Evaluation of the antitumoral effect mediated by IL-12 and HSV-tk genes when delivered by a novel lipid-based system. Biochim Biophys Acta, 2007; 1768:1093-102.
-
(2007)
Biochim Biophys Acta
, vol.1768
, pp. 1093-1102
-
-
Faneca, H.1
Cabrita, A.S.2
Simoes, S.3
Pedroso de Lima, M.C.4
-
33
-
-
68249087951
-
Antitumoral effect of IL 12 gene transfected via liposomes into B16F0 cells
-
Speroni L, Gasparri J, de los ABV, Chiaramoni NS, Smagur A, Szala S, et al. Antitumoral effect of IL 12 gene transfected via liposomes into B16F0 cells. Acta Biochim Pol, 2009; 56:249-53.
-
(2009)
Acta Biochim Pol
, vol.56
, pp. 249-253
-
-
Speroni, L.1
Gasparri, J.2
de los, A.B.V.3
Chiaramoni, N.S.4
Smagur, A.5
Szala, S.6
-
34
-
-
58049200809
-
Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma
-
Daud AI, DeConti RC, Andrews S, Urbas P, Riker AI, Sondak VK, et al. Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma. J Clin Oncol, 2008; 26:5896-903.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5896-5903
-
-
Daud, A.I.1
Deconti, R.C.2
Andrews, S.3
Urbas, P.4
Riker, A.I.5
Sondak, V.K.6
-
35
-
-
0034241855
-
Soluble biodegradable polymer-based cytokine gene delivery for cancer treatment
-
Maheshwari A, Mahato RI, McGregor J, Han S, Samlowski WE, Park JS, et al. Soluble biodegradable polymer-based cytokine gene delivery for cancer treatment. Mol Ther, 2000; 2:121-30.
-
(2000)
Mol Ther
, vol.2
, pp. 121-130
-
-
Maheshwari, A.1
Mahato, R.I.2
McGregor, J.3
Han, S.4
Samlowski, W.E.5
Park, J.S.6
-
36
-
-
28444449782
-
Synthesis and application of a nonviral gene delivery system for immunogene therapy of cancer
-
Fewell JG, Matar M, Slobodkin G, Han SO, Rice J, Hovanes B, et al. Synthesis and application of a nonviral gene delivery system for immunogene therapy of cancer. J Control Release, 2005; 109:288-98.
-
(2005)
J Control Release
, vol.109
, pp. 288-298
-
-
Fewell, J.G.1
Matar, M.2
Slobodkin, G.3
Han, S.O.4
Rice, J.5
Hovanes, B.6
-
37
-
-
33749983751
-
Codelivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer
-
Wang Y, Gao S, Ye WH, Yoon HS, Yang YY. Codelivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer. Nat Mater, 2006; 5:791-6.
-
(2006)
Nat Mater
, vol.5
, pp. 791-796
-
-
Wang, Y.1
Gao, S.2
Ye, W.H.3
Yoon, H.S.4
Yang, Y.Y.5
-
38
-
-
63449093837
-
Targeted cationic poly(D,L-lactic-co-glycolic acid) nanoparticles for gene delivery to cultured cells
-
Diez S, Migueliz I, Tros de Ilarduya C. Targeted cationic poly(D,L-lactic-co-glycolic acid) nanoparticles for gene delivery to cultured cells. Cell Mol Biol Lett, 2009; 14:347-62.
-
(2009)
Cell Mol Biol Lett
, vol.14
, pp. 347-362
-
-
Diez, S.1
Migueliz, I.2
Tros de Ilarduya, C.3
-
39
-
-
0038513487
-
Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice
-
Chew JL, Wolfowicz CB, Mao HQ, Leong KW, Chua KY. Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice. Vaccine, 2003; 21:2720-9.
-
(2003)
Vaccine
, vol.21
, pp. 2720-2729
-
-
Chew, J.L.1
Wolfowicz, C.B.2
Mao, H.Q.3
Leong, K.W.4
Chua, K.Y.5
-
40
-
-
62749135925
-
Chitosan Nbetainates/ DNA self-assembly nanoparticles for gene delivery: In vitro uptake and transfection efficiency
-
Gao Y, Zhang Z, Chen L, Gu W, Li Y. Chitosan Nbetainates/ DNA self-assembly nanoparticles for gene delivery: in vitro uptake and transfection efficiency. Int J Pharm, 2009; 371:156-62.
-
(2009)
Int J Pharm
, vol.371
, pp. 156-162
-
-
Gao, Y.1
Zhang, Z.2
Chen, L.3
Gu, W.4
Li, Y.5
-
41
-
-
0037340617
-
Mesenchymal stem cells, MG63 and HEK293 transfection using chitosan-DNA nanoparticles
-
Corsi K, Chellat F, Yahia L, Fernandes JC. Mesenchymal stem cells, MG63 and HEK293 transfection using chitosan-DNA nanoparticles. Biomaterials, 2003; 24:1255-64.
-
(2003)
Biomaterials
, vol.24
, pp. 1255-1264
-
-
Corsi, K.1
Chellat, F.2
Yahia, L.3
Fernandes, J.C.4
-
42
-
-
0035936972
-
Chitosan-DNA nanoparticles as gene carriers: Synthesis, characterization and transfection efficiency
-
Mao HQ, Roy K, Troung-Le VL, Janes KA, Lin KY, Wang Y, et al. Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency. J Control Release, 2001; 70:399-421.
-
(2001)
J Control Release
, vol.70
, pp. 399-421
-
-
Mao, H.Q.1
Roy, K.2
Troung-Le, V.L.3
Janes, K.A.4
Lin, K.Y.5
Wang, Y.6
-
43
-
-
0035424424
-
In vitro gene delivery mediated by chitosan. effect of pH, serum, and molecular mass of chitosan on the transfection efficiency
-
Sato T, Ishii T, Okahata Y. In vitro gene delivery mediated by chitosan. effect of pH, serum, and molecular mass of chitosan on the transfection efficiency. Biomaterials, 2001; 22:2075-80.
-
(2001)
Biomaterials
, vol.22
, pp. 2075-2080
-
-
Sato, T.1
Ishii, T.2
Okahata, Y.3
-
44
-
-
0037376258
-
Synergistic effect of polyethylenimine and cationic liposomes in nucleic acid delivery to human cancer cells
-
Lee CH, Ni YH, Chen CC, Chou C, Chang FH. Synergistic effect of polyethylenimine and cationic liposomes in nucleic acid delivery to human cancer cells. Biochim Biophys Acta, 2003; 1611:55-62.
-
(2003)
Biochim Biophys Acta
, vol.1611
, pp. 55-62
-
-
Lee, C.H.1
Ni, Y.H.2
Chen, C.C.3
Chou, C.4
Chang, F.H.5
-
45
-
-
0035801903
-
Mechanism of cell transfection with plasmid/chitosan complexes
-
Ishii T, Okahata Y, Sato T. Mechanism of cell transfection with plasmid/chitosan complexes. Biochim Biophys Acta, 2001; 1514:51-64.
-
(2001)
Biochim Biophys Acta
, vol.1514
, pp. 51-64
-
-
Ishii, T.1
Okahata, Y.2
Sato, T.3
-
46
-
-
33646367419
-
In vitro characterization and transfection of IL-2 gene complexes
-
Ozgel G, Akbuga J. In vitro characterization and transfection of IL-2 gene complexes. Int J Pharm. 2006; 315:44-51.
-
(2006)
Int J Pharm
, vol.315
, pp. 44-51
-
-
Ozgel, G.1
Akbuga, J.2
-
47
-
-
0034294817
-
Development of biomaterials for gene therapy
-
Han S, Mahato RI, Sung YK, Kim SW. Development of biomaterials for gene therapy. Mol Ther, 2000; 2:302-17.
-
(2000)
Mol Ther
, vol.2
, pp. 302-317
-
-
Han, S.1
Mahato, R.I.2
Sung, Y.K.3
Kim, S.W.4
-
49
-
-
0142090707
-
Sustained expression in mammalian cells with DNA complexed with chitosan nanoparticles
-
Li XW, Lee DK, Chan AS, Alpar HO. Sustained expression in mammalian cells with DNA complexed with chitosan nanoparticles. Biochim Biophys Acta, 2003; 1630:7-18.
-
(2003)
Biochim Biophys Acta
, vol.1630
, pp. 7-18
-
-
Li, X.W.1
Lee, D.K.2
Chan, A.S.3
Alpar, H.O.4
-
50
-
-
0346634895
-
In vitro cytotoxicity testing of polycations: Influence of polymer structure on cell viability and hemolysis
-
Fischer D, Li Y, Ahlemeyer B, Krieglstein J, Kissel T. In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis. Biomaterials, 2003; 24:1121-31.
-
(2003)
Biomaterials
, vol.24
, pp. 1121-1131
-
-
Fischer, D.1
Li, Y.2
Ahlemeyer, B.3
Krieglstein, J.4
Kissel, T.5
-
51
-
-
33745077164
-
High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation
-
Lavertu M, Methot S, Tran-Khanh N, Buschmann MD. High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation. Biomaterials, 2006; 27:4815-24.
-
(2006)
Biomaterials
, vol.27
, pp. 4815-4824
-
-
Lavertu, M.1
Methot, S.2
Tran-Khanh, N.3
Buschmann, M.D.4
-
52
-
-
34548630860
-
Chitosan nanoparticles for oral drug and gene delivery
-
Bowman K, Leong KW. Chitosan nanoparticles for oral drug and gene delivery. Int J Nanomedicine, 2006; 1:117-28.
-
(2006)
Int J Nanomedicine
, vol.1
, pp. 117-128
-
-
Bowman, K.1
Leong, K.W.2
|