PKCε promotes cardiac mitochondrial and metabolic adaptation to chronic hypobaric hypoxia by GSK3β inhibition

Journal of Cellular Physiology

Volumn 226, Issue 9, 2011, Pages 2457-2468

  Mccarthy, Joy ^a   Lochner, Amanda ^b   Opie, Lionel H ^a   Sack, Michael N ^c   Essop, M Faadiel ^d  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF STELLENBOSCH   (South Africa)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d Cardio Metabolic Research Group (CMRG)   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PALMITIC ACID; PROTEIN KINASE C EPSILON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; ELECTRON MICROSCOPY; GLUCOSE UTILIZATION; HEART MITOCHONDRION; HEART MUSCLE METABOLISM; HEART PERFUSION; HYPOBARISM; HYPOXIA; MALE; MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; ULTRASTRUCTURE; WILD TYPE;

ADAPTATION, PHYSIOLOGICAL; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; CELL HYPOXIA; ENERGY METABOLISM; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GLYCOGEN; GLYCOGEN SYNTHASE KINASE 3; HEART FUNCTION TESTS; HEART VENTRICLES; HYPERTROPHY, RIGHT VENTRICULAR; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICROFILAMENTS; MITOCHONDRIA; MYOCARDIUM; OXYGEN; PEPTIDES; PERFUSION; PRESSURE; PROTEIN KINASE C-EPSILON; PROTEIN TRANSPORT; RABBITS; RNA, MESSENGER;

MUS;

EID: 79958759013     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22592     Document Type: Article

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