Protein kinase C α and ε phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardium

Basic Research in Cardiology

Volumn 105, Issue 2, 2010, Pages 289-300

  Kooij, Viola ^a   Boontje, Nicky ^a   Zaremba, Ruud ^a   Jaquet, Kornelia ^b   Remedios, Cris Dos ^c   Stienen, Ger J M ^a   Van Der Velden, Jolanda ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Cardiac; Contractile proteins; Heart failure; Myofilament function; Phosphorylation; Protein kinase c

Indexed keywords

CALCIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE; MYOSIN BINDING PROTEIN C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C EPSILON; TROPONIN I; CARRIER PROTEIN; MYOSIN-BINDING PROTEIN C; TROPONIN T;

ADOLESCENT; ADULT; AGED; ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; FEMALE; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE CONTRACTILITY; HUMAN; HUMAN TISSUE; MALE; MYOFILAMENT; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; CELL CULTURE; ENZYMOLOGY; HEART FAILURE; HEART MUSCLE; METABOLISM; MIDDLE AGED; PHOSPHORYLATION;

ADOLESCENT; ADULT; CALCIUM; CARRIER PROTEINS; CELLS, CULTURED; FEMALE; HEART FAILURE; HUMANS; MALE; MIDDLE AGED; MYOCARDIUM; PHOSPHORYLATION; PROTEIN KINASE C-ALPHA; PROTEIN KINASE C-EPSILON; TROPONIN I; TROPONIN T; YOUNG ADULT;

EID: 77950362402     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-009-0053-z     Document Type: Article

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