A simplified synthesis of novel dictyostatin analogues with In Vitro activity against epothilone B-resistant cells and antiangiogenic activity in zebrafish embryos

Molecular Cancer Therapeutics

Volumn 10, Issue 6, 2011, Pages 994-1006

  Vollmer, Laura L ^a   Jiménez, Maria ^a   Camarco, Daniel P ^a   Zhu, Wei ^a   Daghestani, Hikmat N ^b   Balachandran, Raghavan ^a   Reese, Celeste E ^a   Lazo, John S ^a,c   Hukriede, Neil A ^b   Curran, Dennis P ^a   Day, Billy W ^a   Vogt, Andreas ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

25,26 DIHYDRODICTYOSTATIN; 6 EPI 25,26 DIHYDRODICTYOSTATIN; 6 EPI DICTYOSTATIN; ANTINEOPLASTIC AGENT; BETA TUBULIN; DISCODERMOLIDE; EPOTHILONE B; PACLITAXEL; UNCLASSIFIED DRUG;

ANTIANGIOGENIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; CYTOTOXICITY; DRUG ANTAGONISM; DRUG POTENTIATION; DRUG SYNTHESIS; EMBRYO; EPIMER; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROTUBULE ASSEMBLY; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; RADIOASSAY; ZEBRA FISH;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; EPOTHILONES; HELA CELLS; HUMANS; MACROLIDES; MICROTUBULES; MITOSIS; PACLITAXEL; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN; ZEBRAFISH;

EID: 79958743694     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-10-1048     Document Type: Article

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