High-content analysis of cancer-cell-specific apoptosis and inhibition of in vivo angiogenesis by synthetic (-)-pironetin and analogs

Chemical Biology and Drug Design

Volumn 74, Issue 4, 2009, Pages 358-368

  Vogt, Andreas ^a,b   McPherson, Peter A ^a   Shen, Xiaoqiang ^b   Balachandran, Raghavan ^b   Zhu, Guangyu ^b   Raccor, Brianne S ^b   Nelson, Scott G ^b   Tsang, Michael ^a   Day, Billy W ^b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Angiogenesis; High content screening; Multi drug resistance; Pironetin; Zebrafish

Indexed keywords

2,3 DIHYDRO 3 HYDROXYPIRONETIN; 3 HYDROXYPIRONETIN; ACID HALIDE; ALDEHYDE; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; DOLASTATIN; PACLITAXEL; PIRONETIN; TUBULIN; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE;

ANIMAL CELL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; HUMAN; HUMAN CELL; LUNG CANCER; LUNG FIBROBLAST; MICROTUBULE ASSEMBLY; MITOSIS INHIBITION; MULTIDRUG RESISTANCE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY; ZEBRA FISH;

ANGIOGENESIS INHIBITORS; ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; CRICETULUS; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICROTUBULES; MITOSIS; NEOVASCULARIZATION, PHYSIOLOGIC; PYRONES; TUBULIN MODULATORS; ZEBRAFISH;

DANIO RERIO;

EID: 70349094948     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2009.00866.x     Document Type: Article

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