Occludin expression in microvessels of neoplastic and non-neoplastic human brain

Neuropathology and Applied Neurobiology

Volumn 27, Issue 5, 2001, Pages 384-395

  Papadopoulos, M C ^a   Saadoun, S ^b   Woodrow, C J ^c   Davies, D C ^a,c   Costa Martins, P ^c   Moss, R F ^a   Krishna, S ^b   Bell, B A ^c  

^a ATKINSON MORLEY S HOSPITAL   (United Kingdom)

^b Departments of Anatomy and Developmental Biology   (United Kingdom)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Astrocytoma; Blood brain barrier; Brain neoplasms; Metastasis; Tight junction; Vascular endothelium; Vasogenic oedema

Indexed keywords

OCCLUDIN;

ADENOCARCINOMA; ADULT; AGED; ANTIBODY LABELING; ARTICLE; ASTROCYTOMA; BRAIN BLOOD VESSEL; BRAIN CANCER; BRAIN EDEMA; BRAIN TISSUE; CANCER GRADING; CLINICAL ARTICLE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DRUG DESIGN; ELECTRON MICROSCOPY; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR WEIGHT; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIGHT JUNCTION;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ASTROCYTOMA; BLOOD-BRAIN BARRIER; BRAIN EDEMA; BRAIN NEOPLASMS; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON; MIDDLE AGED; TIGHT JUNCTIONS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0034762756     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0305-1846.2001.00341.x     Document Type: Article

References (54)

1. Dynamics of cerebral edema. The role of an intact vascular bed in the production and propagation of vasogenic edema
2. Vascular endothelial growth factor induces rapid phosphorylation of tight junction proteins occludin and zonula occluden 1
3. Ultrastructural basis for different pertechnate uptake patterns by various human brain tumors
4. Vascular endothelial growth factor and microvascular permeability
5. Glioblastoma multiforme and anaplastic astrocytoma. Pathologic criteria and prognostic implications
6. COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos
7. Cingulin, a new peripheral component of tight junctions
8. Vascular permeability factor: A unique regulator of blood vessel function
9. Grading of astrocytomas: A simple and reproducible method
10. Survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histological type: And analysis based on surveillance, epidemiology and end results (SEER) data, 1973-91
11. Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures
12. Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
13. A novel integral membrane protein localizing at tight junctions
14. Composition of isolated edema fluid in cold-induced brain edema
15. Quantitative measurements of capillary transport in human brain tumors by computed tomography
16. Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1
17. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin
18. Occludin as a possible determinant of tight junction permeability in endothelial cells
19. Astrocytes induce blood-brain barrier properties in endothelial cells
20. The treatment of glioblastoma multiforme of the brain
21. Hepatocyte growth factor/scatter factor decreases the expression of occludin and transendo-thelial resistance (TER) and increases permeability in human vascular endothelial cells
22. Symplekin, a novel type of tight junction plaque protein
23. Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins
24. Correlates of survival and the Daumas-Duport system for astrocytomas
25. Neuropathological aspects of brain oedema
26. Small synthetic peptides homologous to the first external loop of occludin impair tight junction resealing
27. Scatter factor/hepatocyte growth factor (SF/HGF) content and function in human gliomas
28. Entamoeba histolytica disturbs the tight junction complex in human enteric T84 cell layers
29. Claudin-1 and claudin-5 expression and tight junction morphology are altered in blood vessels of human glioblastoma multiforme
30. Capillary ultrastructure in human metastatic brain tumors
31. Vascular endothelial growth factor expression, vascular volume and capillary permeability in human brain tumors
32. National survey of patterns of care for brain-tumor patients
33. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration
34. Claudin multigene family encoding four-transmembrane domain protein components at tight junction strands
35. Claudin-11/OSP-based tight junctions of myelin sheaths in brain and Sertoli cells in testis
36. Endothelial claudin: Claudin 5/TMVCF constitutes tight junction strands in endothelial cells
37. Occludin 1B, a variant of the tight junction protein occludin
38. 99mTc-glucoheptonate and alteration in blood-brain barrier as determined by cytochemistry and electron microscopy
39. Fine structure localization of a blood-brain barrier to exogenous peroxidase
40. Kinetics of water-soluble contrast media in the central nervous system
41. Contrast media and the brain. The basis of CT and MR imaging enhancement
42. Mammalian occludin in epithelial cells: Its expression and subcellular distribution
43. A modified method for lead staining of thin sections
44. Immunohistochemical study of tight junction-related protein in neovasculature in astrocytic tumor
45. Immunohistochemical demonstration of serum proteins in human cerebral gliomas
46. Ultrastructure of capillary walls in human brain tumors
47. Prognostic factors of well-differentiated astrocytomas in the adult
48. Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia
49. Brain edema, increased intracranial pressure, vascular effects, and other epiphenomena of human brain tumors
50. Occludin confers adhesiveness when expressed in fibroblasts
51. Der, p1 facilitates trans-epithelial allergen delivery by disruption of tight junctions
52. The tight-junction-specific protein ZO-1 is a component of the human and rat blood-brain barriers
53. Monolonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2