Conservation of structural and functional elements of TSC1 and TSC2: A bioinformatic comparison across animal models

Behavior Genetics

Volumn 41, Issue 3, 2011, Pages 349-356

  Serfontein, Jaco ^a   Nisbet, R Ellen R ^b   Howe, Christopher J ^c   De Vries, Petrus J ^c,d  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d CAMBRIDGESHIRE AND PETERBOROUGH NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Evolution; Hamartin; Model organism; Mouse model; TSC1; TSC2; Tuberin; Tuberous sclerosis complex

Indexed keywords

ADENYLATE KINASE; BRAIN ENZYME; BRAIN PROTEIN; CALMODULIN; CYCLIN DEPENDENT KINASE; ESTROGEN RECEPTOR ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; I KAPPA B KINASE BETA; LEUCINE ZIPPER PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE ACTIVATED PROTEIN KINASE 2; P90 RIBOSOMAL PROTEIN S6 KINASE; PROTEIN KINASE B; PROTEIN TSC1; TUBERIN; UNCLASSIFIED DRUG;

ARTICLE; BEHAVIOR GENETICS; BINDING SITE; BIOINFORMATICS; CONSERVATION GENETICS; DICTYOSTELIUM DISCOIDEUM; DISEASE MODEL; DROSOPHILA MELANOGASTER; GENETIC MODEL; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPIC VARIATION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RAT; SCHIZOSACCHAROMYCES POMBE; SEQUENCE HOMOLOGY; SPECIES DIFFERENTIATION; STRONGYLOCENTROTUS; ZEBRA FISH;

ANIMALS; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; HUMANS; MICE; RATS; SCHIZOSACCHAROMYCES; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS; ZEBRAFISH;

ANIMALIA; DANIO RERIO; DICTYOSTELIUM DISCOIDEUM; DROSOPHILA MELANOGASTER; MAMMALIA; MUS MUSCULUS; PANTHERA PARDUS; RATTUS NORVEGICUS; SCHIZOSACCHAROMYCES POMBE; SCHIZOSACCHAROMYCETACEAE; STRONGYLOCENTROTUS PURPURATUS;

EID: 79958212150     PISSN: 00018244     EISSN: 15733297     Source Type: Journal    
DOI: 10.1007/s10519-010-9440-3     Document Type: Article

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