Thoracic aortic disease in tuberous sclerosis complex: Molecular pathogenesis and potential therapies in Tsc2+/- mice

Human Molecular Genetics

Volumn 19, Issue 10, 2010, Pages 1908-1920

  Cao, Jiumei ^a,b   Gong, Limin ^a   Guo, Dong Chuan ^a   Mietzsch, Ulrike ^a   Kuang, Shao Qing ^a   Kwartler, Callie S ^a   Safi, Hazim ^a   Estrera, Anthony ^a   Gambello, Michael J ^a   Milewicz, Dianna M ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYCLIN DEPENDENT KINASE INHIBITOR 1B; ELASTIN; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; S6 KINASE; TUBERIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CASE REPORT; CELL PROLIFERATION; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DRUG TARGETING; ENZYME PHOSPHORYLATION; EXPLANT; GENE MUTATION; HUMAN; HUMAN TISSUE; IN VIVO STUDY; INFANT; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; THORACIC AORTA ANEURYSM; THORACIC AORTA SURGERY; TUBEROUS SCLEROSIS; WILD TYPE;

ANIMALS; AORTA, THORACIC; AORTIC ANEURYSM; CELL PROLIFERATION; CHILD; CONTRACTILE PROTEINS; ELASTIN; HUMANS; MAGNETIC RESONANCE ANGIOGRAPHY; MICE; MUTATION; MYOCYTES, SMOOTH MUSCLE; PEPTIDES; PHENOTYPE; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; THORACIC DISEASES; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; TUNICA INTIMA;

MAMMALIA; MUS;

EID: 77952467376     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq066     Document Type: Article

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