Salen Mn complexes mitigate radiation injury in normal tissues

Anti-Cancer Agents in Medicinal Chemistry

Volumn 11, Issue 4, 2011, Pages 359-372

  Rosenthal, Rosalind A ^a   Fish, Brian ^c   Hill, Richard P ^d   Huffman, Karl D ^a   Lazarova, Zelmira ^c   Mahmood, Javed ^d   Medhora, Meetha ^c   Molthen, Robert ^c   Moulder, John E ^c   Sonis, Stephen T ^b   Tofilon, Philip J ^e   Doctrow, Susan R ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Catalytic antioxidant; Radiation injury; Radiation mitigation; Salen manganese complex

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CAPTOPRIL; CATALASE; EUK 189; EUK 207; GENISTEIN; HYDROGEN PEROXIDE; MANGANESE N,N' ETHYLENEBIS(3 METHOXYSALICYLIDENEAMINE); MANGANESE SALEN CHLORIDE; RADIOPROTECTIVE AGENT; SUPEROXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ASTROCYTE; BONE MARROW TRANSPLANTATION; BRAIN TUMOR; CANCER RADIOTHERAPY; CELL FUNCTION; CENTRAL NERVOUS SYSTEM DISEASE; CONTINUOUS INFUSION; DRUG DELIVERY SYSTEM; DRUG MECHANISM; DRUG STABILITY; ENZYME ACTIVITY; HEAD AND NECK CANCER; HUMAN; HYPERTENSION; IONIZING RADIATION; KIDNEY INJURY; LIPOPHILICITY; LOZENGE; LUNG FIBROSIS; LUNG INJURY; MITOCHONDRION; MUCOSA INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; PROCESS OPTIMIZATION; PROTEINURIA; RADIATION DERMATITIS; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIATION PNEUMONIA; RADIOTHERAPY; REVIEW; SKIN INJURY; TERRORISM; UREA NITROGEN BLOOD LEVEL; UREMIA;

EID: 79958116231     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/187152011795677490     Document Type: Review

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