It is time for a paradigm shift in drug discovery bioanalysis: From SRM to HRMS

Journal of Mass Spectrometry

Volumn 46, Issue 6, 2011, Pages 595-601

  Ramanathan, Ragu ^a   Jemal, Mohammed ^a   Ramagiri, Suma ^b   Xia, Yuan Qing ^a   Humpreys, W Griffith ^a   Olah, Timothy ^a   Korfmacher, Walter A ^c  

^a BRISTOL MYERS SQUIBB   (United States)

^b MDS SCIEX   (Canada)

^c Consultant ^*  (United States)

Author keywords

discovery bioanalysis; full scan MS; HRMS; qual quant; tripleTOF

Indexed keywords

BIOANALYSIS; FULL-SCAN MS; HRMS; QUAL/QUANT; TRIPLETOF;

CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; STANDARDIZATION;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

BIOLOGICAL MARKER; BUSPIRONE; DRUG METABOLITE; NEFAZODONE; PREDNISOLONE; PREDNISONE; RESERPINE;

ARTICLE; DEGRADATION; DRUG DEVELOPMENT; DRUG INDUSTRY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROCESS MONITORING; PROCESS OPTIMIZATION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SELECTED REACTION MONITORING; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; WORKFLOW;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DISCOVERY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 79958110797     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1921     Document Type: Article

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