PXR prevents cholesterol gallstone disease by regulating biosynthesis and transport of bile salts

Gastroenterology

Volumn 140, Issue 7, 2011, Pages 2095-2106

  He, Jinhan ^a   Nishida, Shigeru ^b   Xu, Meishu ^a   Makishima, Makoto ^b   Xie, Wen ^a,c  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b NIHON UNIVERSITY   (Japan)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Fgf15; Gene Regulation; Nuclear Receptor; PCN; Transgenic Mice

Indexed keywords

16ALPHA CYANOPREGNENOLONE; ABC TRANSPORTER; ABC TRANSPORTER G5; ABC TRANSPORTER G8; BILE ACID; BILE SALT; CHOLESTANETRIOL 26 MONOOXYGENASE; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; CYTOCHROME P450; CYTOCHROME P450 7B1; CYTOCHROME P450 8B1; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 15; HYPERICUM PERFORATUM EXTRACT; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 2; ORGANIC ANION TRANSPORTER 4; PHOSPHOLIPID; PREGNANE X RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE ACID METABOLISM; BILE ACID SYNTHESIS; CHOLESTEROL BILE LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL STONE; CONTROLLED STUDY; CRYSTALLIZATION; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; ILEUM; LIPID BILE LEVEL; LIPOLYSIS; LIVER; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION;

EID: 79958104994     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.02.055     Document Type: Article

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