Identification of novel pregnane X receptor activators from traditional Chinese medicines

Journal of Ethnopharmacology

Volumn 136, Issue 1, 2011, Pages 137-143

  Yu, Chunna ^a,b   Chai, Xiaojuan ^a   Yu, Lushan ^a   Chen, Shuqing ^a   Zeng, Su ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b HANGZHOU NORMAL UNIVERSITY   (China)

Author keywords

Bioactive compound; CYP3A4; Herb drug interaction; Induction; Pregnane X receptor; Traditional Chinese medicine

Indexed keywords

ALCOHOL; ARTEMISIA SCOPARIA EXTRACT; ATRACTYLODES MACROCEPHALA EXTRACT; BERBERINE; CHINESE ANGELICA EXTRACT; CHINESE DRUG; COPTIS CHINENSIS EXTRACT; CYTOCHROME P450 3A4; EPIMEDIUM BREVICORNUM EXTRACT; GARDENIA EXTRACT; GINKGO BILOBA EXTRACT; LIGUSTICUM CHUANXIONG EXTRACT; LIGUSTILIDE; LYCIUM EXTRACT; OPHIOPOGON JAPONICUS EXTRACT; PAEONIA LACTIFLORA EXTRACT; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; POLYGONUM MULTIFLORUM EXTRACT; PREGNANE X RECEPTOR; REHMANNIA EXTRACT; RESVERATROL; SCHISANDRA CHINENSIS EXTRACT; SCHISANTHERIN A; SILYBUM MARIANUM EXTRACT; TRICHOSANTHES KIRILOWII EXTRACT; UNCLASSIFIED DRUG;

ARTEMISIA SCOPARIA; ARTICLE; ATRACTYLODES; ATRACTYLODES MACROCEPHALA; CELL ASSAY; CHINESE ANGELICA; CHINESE MEDICINE; CONTROLLED STUDY; COPTIS CHINENSIS; DRUG ACTIVATION; DRUG IDENTIFICATION; DRUG METABOLISM; DRUG SCREENING; EPIMEDIUM; EPIMEDIUM BREVICORNUM; GARDENIA; GINKGO BILOBA; HUMAN; HUMAN CELL; LIGUSTICUM CHUANXIONG; LYCIUM; MEDICINAL PLANT; OPHIOPOGON JAPONICUS; PAEONIA LACTIFLORA; PLANT ROOT; POLYGONUM MULTIFLORUM; REHMANNIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHISANDRA CHINENSIS; SIGNAL TRANSDUCTION; SILYBUM MARIANUM; TRICHOSANTHES KIRILOWII;

4-BUTYROLACTONE; ANGIOSPERMS; BERBERINE; CYCLOOCTANES; CYTOCHROME P-450 CYP3A; DIOXOLES; DRUGS, CHINESE HERBAL; GENES, REPORTER; HEP G2 CELLS; HERB-DRUG INTERACTIONS; HUMANS; LIGNANS; MEDICINE, CHINESE TRADITIONAL; PLANTS, MEDICINAL; RECEPTORS, STEROID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STILBENES;

ANGELICA SINENSIS; ARTEMISIA SCOPARIA; ATRACTYLODES MACROCEPHALA; COPTIS CHINENSIS; EPIMEDIUM BREVICORNUM; GARDENIA; GINKGO BILOBA; LIGUSTICUM CHUANXIONG; LYCIUM CHINENSE; OPHIOPOGON JAPONICUS; PAEONIA LACTIFLORA; POLYGONUM MULTIFLORUM; REHMANNIA; SCHISANDRA CHINENSIS; SILYBUM MARIANUM; TRICHOSANTHES KIRILOWII;

EID: 79958103448     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.04.022     Document Type: Article

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