PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA

Chemico-Biological Interactions

Volumn 177, Issue 1, 2009, Pages 58-64

  Yu, Chunna ^a   Ye, Shanshan ^a   Sun, Hongying ^a   Liu, Yao ^a   Gao, Lingbo ^a   Shen, Chaofeng ^b   Chen, Shuqing ^a   Zeng, Su ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Cryptotanshinone; CYP3A4; Induction; PXR; Tanshinone IIA

Indexed keywords

CONSTITUTIVE ANDROSTANE RECEPTOR; CRYPTOTANSHINONE; CYTOCHROME P450 3A4; GLUCOCORTICOID RECEPTOR; PREGNANE X RECEPTOR; SALVIA MILTIORRHIZA EXTRACT; TANSHINONE I; TANSHINONE IIA;

ARTICLE; CEREBROVASCULAR DISEASE; CHINESE MEDICINE; DRUG MECHANISM; DRUG STRUCTURE; ISCHEMIC HEART DISEASE; REPORTER GENE; SALVIA MILTIORRHIZA; TRANSCRIPTION INITIATION;

CELL LINE, TUMOR; CYTOCHROME P-450 CYP3A; DRUGS, CHINESE HERBAL; ENZYME INDUCTION; GENES, REPORTER; HUMANS; PHENANTHRENES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, GLUCOCORTICOID; RECEPTORS, STEROID; RECOMBINANT PROTEINS; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

RODENTIA; SALVIA MILTIORRHIZA;

EID: 57349177645     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.08.013     Document Type: Article

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