The involvement of TRPA1 channel activation in the inflammatory response evoked by topical application of cinnamaldehyde to mice

Life Sciences

Volumn 88, Issue 25-26, 2011, Pages 1077-1087

  Silva, Cássia Regina ^a   Oliveira, Sara Marchesan ^a   Rossato, Mateus Fortes ^a   Dalmolin, Gerusa Duarte ^b   Guerra, Gustavo Petri ^a   Prudente, Arthur Da Silveira ^c   Cabrini, Daniela Almeida ^c   Otuki, Michel Fleith ^d   André, Eunice ^e   Ferreira, Juliano ^a,b  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^c FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^d STATE UNIVERSITY OF PONTA GROSSA   (Brazil)

^e FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

Author keywords

Capsaicin; Edema; Mustard oil; Skin irritation; TRP

Indexed keywords

APREPITANT; CAMPHOR; CAPSAICIN; CINNAMALDEHYDE; HC 030031; MYELOPEROXIDASE; NEUROPEPTIDE; RECEPTOR BLOCKING AGENT; RUTHENIUM RED; TACHYKININ; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DESENSITIZATION; EAR EDEMA; EDEMA; ENZYME ACTIVITY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; LEUKOCYTE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SENSITIZATION; SKIN; WESTERN BLOTTING;

ACROLEIN; ADMINISTRATION, TOPICAL; ANIMALS; BLOTTING, WESTERN; CAPSAICIN; DERMATITIS, CONTACT; EDEMA; MALE; MICE; PEROXIDASE; SKIN; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

DRYOBALANOPS; MUS;

EID: 79958034896     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.03.017     Document Type: Article

References (48)

1. Akopian AN, Ruparel NB, Jeske NA, Hargreaves KM. Transient receptor potential TRPA1 channel desensitization in sensory neurons is agonist dependent and regulated by TRPV1-directed internalization. J Physiol 2007;583:175-93. (Pubitemid 47244252)
2. Andrade EL, Ferreira J, André E, Calixto JB. Contractile mechanisms coupled to TRPA1 receptor activation in rat urinary bladder. Biochem Pharmacol 2006;28:104-14. (Pubitemid 43795342)
3. Atoyan R, Shander D, Botchkareva NV. Non-neuronal expression of transient receptor potential type A1 (TRPA1) in human skin. J Investig Dermatol 2009;129:2312-5.
4. Bandell M, Story GM, Hwang SW, Viswanath V, Eid SR, Petrus MJ, et al. Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron 2004;41:849-57. (Pubitemid 38429729)
5. Bánvolgyi A, Pozsgai G, Brain S, Helyes Z, Szolcsa J, Ghosh M, et al. Mustard oil induces a transient receptor potential vanilloid 1 receptor-independent neurogenic inflammation and a non-neurogenic cellular Inflammatory component in mice. Neuroscience 2004;125:449-59. (Pubitemid 38446750)
6. Bautista DM, Movahed P, Hinman A, Axelsson HE, Sterner O, Högestätt ED, et al. Pungent products from garlic activate the sensory ion channel TRPA1. Proc Natl Acad Sci US A 2005;102:12248-52. (Pubitemid 41291160)
7. Bickers D, Calow P, Greim H, Hanifin JM, Rogers AE, Saurat JH, et al. A toxicologic and dermatologic assessment of cinnamyl alcohol, cinnamaldehyde and cinnamic acid when used as fragrance ingredients. Food Chem Toxicol 2005;43:799-836. (Pubitemid 40467562)
8. Birô T, Kovács L. An "ice-cold" TR(i)P to skin biology: the role of TRPA1 in human epidermal keratinocytes. J Investig Dermatol 2009;129:2096-9.
9. Calixto JB, Kassuya CA, André E, Ferreira J. Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions. Pharmacol Ther 2005;106:179-208. (Pubitemid 40603864)
10. Calvo IR, Ocón B, Moya PM, Suárez MD, Zarzuelo A, Augustin OM. Reversible Ponceau stainig as a loading control alternative to action in Western blots. Anal Biochem 2010;401:318-20.
11. Caspani O, Heppenstall PA. TRPA1 and cold transduction: an unresolved issue? J Gen Physiol 2008;133:245-9.
12. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997;389:816-24. (Pubitemid 27462969)
13. Chichorro JG, Zampronio AR, Cabrini DA, Franco CR, Rae GA. Mechanisms operated by endothelin ETA and ETB receptors in the trigeminal ganglion contribute to orofacial thermal hyperalgesia induced by infraorbital nerve constriction in rats. Neuropeptid 2009;43:133-42.
14. Cocchiara J, Letizia CS, Lalko J, Lapczynski A, Api AM. Fragrance material review on cinnamaldehyde. Food Chem Toxicol 2005;43:867-923. (Pubitemid 40462070)
15. Corey DP, Garcia-Anoveros J, Holt JR, Kwan KY, Lin SY, Vollrath MA, et al. TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells. Nature 2004;432:723-30. (Pubitemid 39656287)
16. Dunham JP, Kelly S, Donaldson LF. Inflammation reduces mechanical thresholds in a population of transient receptor potential channel A1-expressing nociceptors in the rat. Eur J Neurosci 2008;27:3151-60. (Pubitemid 351847301)
17. Ferreira J, Trichês KM, Medeiros R, Calixto JB. Mechanisms involved in the nociception produced by peripheral protein kinase c activation in mice. Pain 2005;117:171-81. (Pubitemid 41764785)
18. Gábor M, Ra'zga Z. Development and inhibition of mouse ear oedema induced with capsaicin. Agents Actions 1992;36:83-6.
19. Gamse R, Holzer P, Lembeck F. Decrease of substance P in primary afferent neurones and impairment of neurogenic plasma extravasation by capsaicin. Br J Pharmacol 1980;68:207-13. (Pubitemid 10131989)
20. Guo JY, Huo HR, Zhao BS, Liu HB, Li LF, Ma YY, et al. Cinnamaldehyde reduces IL-1beta-induced cyclooxygenase-2 activity in rat cerebral microvascular endothelial cells. Eur J Pharmacol 2006;537:174-80.
21. Huang CH, Kuo IC, Xu H, Lee YS, Chua KY. Mite allergen induces allergic dermatitis with concomitant neurogenic inflammation in mouse. J Investig Dermatol 2003;121:289-93. (Pubitemid 36969902)
22. Inoue H, Nagata N, Koshihara Y. Involvement of substance P as a mediator in capsaicin-induced mouse ear oedema. Inflamm Res 1995;44:470-4.
23. Inoue H, Asaka T, Nagata N, Koshihara Y. Mechanism of mustard oil-induced skin inflammation in mice. Eur J Pharmacol 1997;333:231-40. (Pubitemid 27387396)
24. Jancsó N, Jancsó-Gábor A, Szolcsányi J. Direct evidence for neurogenic inflammation and its prevention by denervation and by pretreatment with capsaicin. Br J Pharmacol Chemother 1967;31:138-51.
25. Jancsó N, Kiraly E, Jancsó-Gábor A. Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones. Nature 1977;270:741-3. (Pubitemid 8239254)
26. Johansen JD, Andersen KE, Rastogi SC. Threshold responses in cinnamic-aldehyde-sensitive subjects: results and methodological aspects. Contact Dermatitis 1996;34:165-71. (Pubitemid 26083666)
27. Jordt SE, Bautista DM, Chuang HH, McKemy DD, Zygmunt PM, Högestätt ED, et al. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 2004;427:260-5. (Pubitemid 38112043)
28. Kadyk DL, McCarter K, Achen F, Belsito DV. Quality of life in patients with allergic contact dermatitis. J Am Acad Dermatol 2003;49:1037-48. (Pubitemid 37475475)
29. Kasting GB, Francis WR, Bowman LA, Kinnett GO. Percutaneous absorption of vanilloids: in vivo and in vitro studies. J Pharm Sci 1997;86:142-6. (Pubitemid 127489672)
30. Kim DK, Lillehoj HS, Lee SH, Jang SI, Bravo D. High-throughput gene expression analysis of intestinal intraepithelial lymphocytes after oral feeding of carvacrol, cinnamaldehyde, or Capsicum oleoresin. Poult Sci 2010;89:68-81.
31. Kwan KY, Allchorne AJ, Vollrath MA, Christensen AP, Zhang DS, Woolf CJ, et al. TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron 2006;50:277-89.
32. Lahti A, Maibach HI. An animal model for nonimmunologic contact urticaria. Toxicol Appl Pharmacol 1984;76:219-24. (Pubitemid 15218200)
33. Lahti A, McDonald DM, Tammi R, Maibach HI. Pharmacological studies on nonimmunologic contact urticaria in guinea pigs. Arch Dermatol Res 1986;279:44-9. (Pubitemid 17042712)
34. Macpherson LJ, Hwang SW, Miyamoto T, Dubin AE, Patapoutian A, Story GM. More than cool: promiscuous relationships of menthol and other sensory compounds. Mol Cell Neurosci 2006;32:335-43. (Pubitemid 44163229)
35. Peters EM, Ericson ME, Hosoi J, Seiffert K, Hordinsky MK, Ansel JC, et al. Neuropeptide control mechanisms in cutaneous biology: physiological and clinical significance. J Investig Dermatol 2006;126:1937-47.
36. Pomonis JD, Rogers SD, Peters CM, Ghilardi JR, Mantyh PW. Expression and localization of endothelin receptors: implications for the involvement of peripheral glia in nociception. J Neurosci 2001;21:1999-2006.
37. Pozsgai G, Sándor K, Perkecz A, Szolcsányi J, Helyes Z, Brain SD, et al. Topical acetone treatment induces neurogenic oedema on the sensitized mouse ear: an in vivo study using transient receptor potential vanilloid 1 (TRPV1) receptor knockout mice. Inflamm Res 2007;56(11):459-67 Nov.
38. Recio MC, Giner RM, Uriburu L, Mànêz S, Cerda' M, De la Fuente JR, Ríos JL. In vivo activity of pseudoguaianolide sesquiterpene lactones in acute and chronic inflammation. Life Sci 2000;66:2509-18.
39. Ruparel NB, Patwardhan AM, Akopian AN, Hargreaves KM. Homologous and heterologous desensitization of capsaicin and mustard oil responses utilize different cellular pathways in nociceptors. Pain 2008;135:271-9. (Pubitemid 351324025)
40. Scholzen T, Armstrong CA, Bunnett NW, Luger TA, Olerud JE, Ansel JC. Neuropeptides in the skin: interactions between the neuroendocrine and the skin immune systems. Exp Dermatol 1998;7:81-96. (Pubitemid 28210211)
41. Slodownik D, Lee A, Nixon R. Irritant contact dermatitis: a review. Australas J Dermatol 2008;49:1-11.
42. Story GM, Peier AM, Reeve AJ, Eid SR, Mosbacher J, Hricik TR, et al. Patapoutian A. ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 2003;112:819-29.
43. Suzuki K, Ota H, Sasagawa S, Sakatani T, Fujikura T. Assay method for myeloperoxidase in human polymorphonuclear leukocytes. Anal Biochem 1983;132:345-52. (Pubitemid 13048589)
44. Thorne PS, Hawk C, Kaliszewski SD, Guiney PD. The noninvasive mouse ear swelling assay. II. Testing the contact sensitizing potency of fragrances. Fundam Appl Toxicol 1991;17:807-20.
45. Trevisani M, Siemens J, Materazzi S, Bautista DM, Nassini R, Campi B, et al. 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proc Natl Acad Sci U S A 2007;104:13519-24. (Pubitemid 47293977)
46. Xu H, Blair NT, Clapham DE. Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. J Neurosci 2005;25:8924-37. (Pubitemid 41384461)
47. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983;16:109-10. (Pubitemid 13058546)
48. Zurborg S, Yurgionas B, Jira JA, Caspani O, Heppenstall PA. Direct activation of the ion channel TRPA1 by Ca2+. Nat Neurosci 2007;10:277-9.