Improvement of some physicochemical properties of arundic acid, (R)-(-)-2-propyloctanonic acid, by complexation with hydrophilic cyclodextrins

International Journal of Pharmaceutics

Volumn 413, Issue 1-2, 2011, Pages 63-72

  Miyamoto, Yuji ^a,b   Nakahara, Mai ^a   Motoyama, Keiichi ^a   Ishiguro, Takako ^a,c   Oda, Yoshiki ^d   Yamanoi, Takashi ^d   Okamoto, Ichiro ^b   Yagi, Akira ^b   Nishimura, Hidekatsu ^b   Hirayama, Fumitoshi ^c   Uekama, Kaneto ^c   Arima, Hidetoshi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b ONO PHARMACEUTICAL CO   (Japan)

^c SOJO UNIVERSITY   (Japan)

^d NOGUCHI INSTITUTE   (Japan)

Author keywords

Arundic acid; Complexation; Cyclodextrins; Powderization; Solubilization; Taste masking

Indexed keywords

ARUNDIC ACID; CYCLODEXTRIN;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG ADSORPTION; DRUG SOLUTION; ELECTRIC POTENTIAL; HUMAN; HUMAN EXPERIMENT; HYDROPHILICITY; NORMAL HUMAN; PHYSICAL CHEMISTRY; POWDER; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID STATE; SOLUBILIZATION; TASTE; ULTRAVIOLET SPECTROSCOPY;

BETA-CYCLODEXTRINS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EXCIPIENTS; GAMMA-CYCLODEXTRINS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; NOOTROPIC AGENTS; OCTANOIC ACIDS; PHYSICOCHEMICAL PROCESSES; POWDERS; SOLUBILITY; SOLUTIONS; TASTE; TASTE PERCEPTION;

EID: 79957985078     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.04.022     Document Type: Article

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