Reduction of bitterness of antihistaminic drugs by complexation with β-cyclodextrins

Journal of Pharmaceutical Sciences

Volumn 100, Issue 5, 2011, Pages 1935-1943

  Ono, Nao ^a   Miyamoto, Yuji ^a   Ishiguro, Takako ^b   Motoyama, Keiichi ^a   Hirayama, Fumitoshi ^b   Iohara, Daisuke ^b   Seo, Hakaru ^b   Tsuruta, Satoshi ^b   Arima, Hidetoshi ^a   Uekama, Kaneto ^b  

^a KUMAMOTO UNIVERSITY   (Japan)

^b SOJO UNIVERSITY   (Japan)

Author keywords

Antihistaminic drug; Artificial taste sensor; Cyclodextrins; Drug interaction; Inclusion compounds; Liposomes; Preformulation; Taste masking

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ALPHA CYCLODEXTRIN; ANTIHISTAMINIC AGENT; BETA CYCLODEXTRIN; CETIRIZINE; CHLORPHENIRAMINE; DIPHENHYDRAMINE; EPINASTINE; GAMMA CYCLODEXTRIN; HYDROXYZINE; LIPOSOME;

ADSORPTION; ARTICLE; BITTER TASTE; CHEMICAL INTERACTION; COMPLEX FORMATION; CONCENTRATION RESPONSE; DRUG STABILITY; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN;

EID: 79952206636     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22417     Document Type: Article

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