Engineered ΔguaB-A ΔvirG Shigella flexneri 2a strain CVD 1205: Construction, safety, immunogenicity, and potential efficacy as a mucosal vaccine

Infection and Immunity

Volumn 64, Issue 8, 1996, Pages 3055-3061

  Noriega, Fernando R ^a   Losonsky, Genevieve ^a   Lauderbaugh, Carol ^a   Liao, Fang Ming ^a   Wang, Jin Yuan ^a   Levine, Myron M ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CVD 1205; GUANINE; SHIGELLA VACCINE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BACTERIAL VACCINE; BACTERIUM ANTIBODY; DNA BINDING PROTEIN; IMMUNOGLOBULIN A; LIVE VACCINE; RECOMBINANT VACCINE; TRANSCRIPTION FACTOR; VIRG PROTEIN, SHIGELLA FLEXNERI;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUXOTROPHIC MUTANT; BACTERIAL GENE; CONTROLLED STUDY; DELETION MUTANT; GUINEA PIG; HELA CELL; HUMAN; HUMAN CELL; IMMUNOGENICITY; INTRANASAL DRUG ADMINISTRATION; KERATOCONJUNCTIVITIS; NONHUMAN; OPERON; PRIORITY JOURNAL; SHIGELLA FLEXNERI; STRAIN DIFFERENCE; ANIMAL; BIOSYNTHESIS; CLASSIFICATION; DYSENTERY, BACILLARY; GENE DELETION; GENETIC ENGINEERING; GENETICS; HELA CELL LINE; IMMUNOLOGY; MOLECULAR GENETICS; NOSE MUCOSA; NUCLEOTIDE SEQUENCE; PATHOGENICITY; SAFETY;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL PROTEINS; BACTERIAL VACCINES; BASE SEQUENCE; DNA-BINDING PROTEINS; DYSENTERY, BACILLARY; GENETIC ENGINEERING; GUINEA PIGS; HELA CELLS; HUMANS; IMMUNOGLOBULIN A; MOLECULAR SEQUENCE DATA; NASAL MUCOSA; SAFETY; SEQUENCE DELETION; SHIGELLA FLEXNERI; TRANSCRIPTION FACTORS; VACCINES, ATTENUATED; VACCINES, SYNTHETIC;

EID: 0029665144     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.8.3055-3061.1996     Document Type: Article

References (33)

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