A 3D cartilage - Inflammatory cell culture system for the modeling of human osteoarthritis

Biomaterials

Volumn 32, Issue 24, 2011, Pages 5581-5589

  Sun, Lin ^a   Wang, Xiuli ^a,b   Kaplan, David L ^a  

^a Tufts University   (United States)

^b DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

Author keywords

Inflammation; Osteoarthritis; Silk; Tissue engineered cartilage

Indexed keywords

ANIMAL MODEL; APOPTOSIS; CARTILAGE TISSUES; CASPASE-3; CELL LINES; CELL VIABILITY; CHONDROCYTES; CHRONDROCYTE; CONDITIONED MEDIUM; CULTURE SYSTEMS; CYTOKINE STIMULATION; CYTOKINE TREATMENT; CYTOKINES; HUMAN CARTILAGE; HUMAN SYSTEM; HUMAN TISSUES; IMMUNE CELLS; IMMUNOHISTOCHEMISTRY; IN-VITRO; INFLAMMATION; INFLAMMATORY CELLS; INFLAMMATORY MEDIATORS; MATRIX COMPOSITION; MATRIX SYNTHESIS; OSTEOARTHRITIS; PATHOGENIC MECHANISMS; POROUS SCAFFOLD; PRIMARY CHONDROCYTES; SILK PROTEINS; STATIC CULTURE; SYSTEMATIC STUDY; TISSUE ENGINEERED CARTILAGE; TISSUE MODELS; TRANSCRIPT LEVEL; TYPE II;

ANIMAL CELL CULTURE; BODY FLUIDS; CARTILAGE; CELL DEATH; COLLAGEN; GENE EXPRESSION; PATHOLOGY; RATING; SCAFFOLDS (BIOLOGY); SILK; TISSUE;

THREE DIMENSIONAL;

AGGRECAN; AGGRECANASE 1; CASPASE 3; COLLAGEN TYPE 10; COLLAGEN TYPE 2; COLLAGENASE 3; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CARTILAGE CELL; CARTILAGE MATRIX; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE RELEASE; DISEASE MODEL; DOWN REGULATION; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INFLAMMATORY CELL; MACROPHAGE; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THREE DIMENSIONAL IMAGING; TISSUE ENGINEERING; UPREGULATION;

APOPTOSIS; CARTILAGE; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL ENLARGEMENT; CELL LINE, TUMOR; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE II; CULTURE MEDIA, CONDITIONED; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOHISTOCHEMISTRY; OSTEOARTHRITIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TETRADECANOYLPHORBOL ACETATE;

ANIMALIA;

EID: 79957901671     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.04.028     Document Type: Article

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