Stimulation of cyclooxygenase-2-activity by nitric oxide-derived species in rat chondrocyte: Lack of contribution to loss of cartilage anabolism

Biochemical Pharmacology

Volumn 61, Issue 8, 2001, Pages 965-978

  Nédélec, Emmanuelle ^a   Abid, Amr ^a   Cipolletta, Christine ^a   Presle, Nathalie ^a   Terlain, Bernard ^a   Netter, Patrick ^a   Jouzeau, Jean Yves ^a  

^a CNRS   (France)

Author keywords

Chondrocytes; Cyclooxygenase 2; Interleukin 1 ; Nitric oxide synthase inhibitors; Non steroidal anti inflammatory drugs; Peroxynitrite

Indexed keywords

3,5 DIISOPROPYLSALICYLATE COPPER; CATALASE; CYCLOHEXIMIDE; CYCLOOXYGENASE 2; INDOMETACIN; INTERLEUKIN 1BETA; MESSENGER RNA; METHYLISOTHIOUREA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N(G) METHYLARGININE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; NITRITE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; SODIUM SULFATE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CARTILAGE CELL; CARTILAGE DEGENERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOGLYCAN SYNTHESIS; RAT; TIME;

ANIMALS; CARTILAGE; CHONDROCYTES; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INDOMETHACIN; INTERLEUKIN-1; ISOENZYMES; MALE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; NITROBENZENES; OMEGA-N-METHYLARGININE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEOGLYCANS; RATS; RATS, WISTAR; SULFONAMIDES; THIOUREA;

EID: 0035871921     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00559-7     Document Type: Article

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