Male IL-6 gene knock out mice developed more advanced osteoarthritis upon aging

Osteoarthritis and Cartilage

Volumn 13, Issue 1, 2005, Pages 66-73

  de Hooge, Alfons S K ^a   van de Loo, Fons A J ^a   Bennink, Miranda B ^a   Arntz, Onno J ^a   de Hooge, Pirter ^b   van den Berg, Wim B ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b DEPARTMENT OF SURGERY   (Netherlands)

Author keywords

Interleukin 6; Knock out mice; Osteoarthritis; Proteoglycan synthesis

Indexed keywords

COLLAGENASE; INTERLEUKIN 6; PROTEOGLYCAN; SULFATE; SULFUR 35;

AGE DISTRIBUTION; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE MINERAL; CARTILAGE DEGENERATION; CLINICAL FEATURE; CONTROLLED STUDY; DENSITY; DISEASE PREDISPOSITION; DISEASE SEVERITY; DUAL ENERGY X RAY ABSORPTIOMETRY; EX VIVO STUDY; EXTRACELLULAR MATRIX; FEMALE; HISTOPATHOLOGY; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; INCIDENCE; KNEE LIGAMENT; KNEE OSTEOARTHRITIS; KNOCKOUT MOUSE; MALE; MEASUREMENT; MOUSE; NONHUMAN; OSTEOSCLEROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOGLYCAN SYNTHESIS; SEX DIFFERENCE; STRAIN DIFFERENCE; WILD TYPE;

AGING; ANIMALS; ARTHRITIS, EXPERIMENTAL; BONE DENSITY; CARTILAGE, ARTICULAR; CHONDROCYTES; COLLAGENASES; FEMALE; INTERLEUKIN-6; LIGAMENTS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOARTHRITIS; PROSTAGLANDINS; SCLEROSIS; SEX FACTORS; TIBIA;

EID: 12144255852     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2004.09.011     Document Type: Article

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