Cyclic AMP-induced p53 destabilization is independent of EPAC in pre-B acute lymphoblastic leukemia cells in vitro

Journal of Receptors and Signal Transduction

Volumn 31, Issue 3, 2011, Pages 256-263

  Safa, Majid ^a   Kazemi, Ahmad ^a   Zaker, Farhad ^a   Razmkhah, Farnaz ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Apoptosis; cAMP; Mdm2; PKA

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CYCLIC AMP; CYCLIC AMP RECEPTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DOXORUBICIN; FORSKOLIN; ISOBUTYLMETHYLXANTHINE; PROTEIN MDM2; PROTEIN P21; PROTEIN P53;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA DAMAGE; FLOW CYTOMETRY; GENE AMPLIFICATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; WESTERN BLOTTING;

1-METHYL-3-ISOBUTYLXANTHINE; APOPTOSIS; CELL LINE, TUMOR; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA DAMAGE; DOXORUBICIN; FORSKOLIN; GENE EXPRESSION REGULATION, LEUKEMIC; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HISTONE DEACETYLASE 1; HUMANS; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STABILITY; PROTO-ONCOGENE PROTEINS C-MDM2; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79957802896     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.3109/10799893.2011.578140     Document Type: Article

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