Inhibitory role of cAMP on doxorubicin-induced apoptosis in pre-B ALL cells through dephosphorylation of p53 serine residues

Apoptosis

Volumn 15, Issue 2, 2010, Pages 196-203

  Safa, Majid ^a   Kazemi, Ahmad ^a   Zand, Hamid ^b   Azarkeivan, Azita ^c   Zaker, Farhad ^a   Hayat, Parisa ^a  

^a IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c IRANIAN BLOOD TRANSFUSION ORGANIZATION   (Iran)

Author keywords

Apoptosis; CAMP; Doxorubicin; P53; Wild type p53 cancer cells

Indexed keywords

CYCLIC AMP; DOXORUBICIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DEPHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPRESSOR GENE;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CYCLIC AMP; DNA DAMAGE; DNA-BINDING PROTEINS; DOXORUBICIN; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; INTRACELLULAR SPACE; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PHOSPHOSERINE; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEIN PHOSPHATASE 1; PROTEIN PHOSPHATASE 2; PROTEIN-SERINE-THREONINE KINASES; SERINE; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 77949265520     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-009-0417-8     Document Type: Article

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