메뉴 건너뛰기




Volumn 49, Issue 7, 2011, Pages 1565-1571

Induction of ROS, p53, p21 in DEHP- and MEHP-exposed LNCaP cells-protection by selenium compounds

Author keywords

DEHP; MEHP; P21; P53; ROS; Selenium

Indexed keywords

PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SELENIUM DERIVATIVE; SELENOMETHIONINE; SODIUM SELENITE;

EID: 79957666653     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.04.001     Document Type: Article
Times cited : (55)

References (61)
  • 1
    • 0033427595 scopus 로고    scopus 로고
    • Micronutrient deficiencies. A major cause of DNA damage
    • Ames B.N. Micronutrient deficiencies. A major cause of DNA damage. Ann. N.Y. Acad. Sci. 1999, 889:87-106.
    • (1999) Ann. N.Y. Acad. Sci. , vol.889 , pp. 87-106
    • Ames, B.N.1
  • 2
    • 0037497143 scopus 로고    scopus 로고
    • Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate
    • Barlow N.J., Phillips S.L., Wallace D.G., Sar M., Gaido K.W., Foster P.M. Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate. Toxicol. Sci. 2003, 7:431-441.
    • (2003) Toxicol. Sci. , vol.7 , pp. 431-441
    • Barlow, N.J.1    Phillips, S.L.2    Wallace, D.G.3    Sar, M.4    Gaido, K.W.5    Foster, P.M.6
  • 4
    • 33646584544 scopus 로고    scopus 로고
    • Mechanisms underlying the anti-androgenic effects of diethylhexyl phthalate in fetal rat testis
    • Borch J., Metzdorff S.B., Vinggaard A.M., Brokken L., Dalgaard M. Mechanisms underlying the anti-androgenic effects of diethylhexyl phthalate in fetal rat testis. Toxicology 2006, 223:144-155.
    • (2006) Toxicology , vol.223 , pp. 144-155
    • Borch, J.1    Metzdorff, S.B.2    Vinggaard, A.M.3    Brokken, L.4    Dalgaard, M.5
  • 6
  • 9
    • 0025963166 scopus 로고
    • Selenium in forage crops and cancer mortality in US counties
    • Clark L.C., Cantor K.P., Allaway W.H. Selenium in forage crops and cancer mortality in US counties. Arch. Environ. Health 1991, 46:37-42.
    • (1991) Arch. Environ. Health , vol.46 , pp. 37-42
    • Clark, L.C.1    Cantor, K.P.2    Allaway, W.H.3
  • 10
    • 34648813720 scopus 로고    scopus 로고
    • ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
    • D'Autréaux B., Toledano M.B. ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat. Rev. Mol. Cell Biol. 2007, 8:813-824.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 813-824
    • D'Autréaux, B.1    Toledano, M.B.2
  • 12
    • 79957636982 scopus 로고    scopus 로고
    • Reproductive toxicity of di(2-ethylhexyl)phthalate in selenium-supplemented and selenium-deficient rats
    • in press, doi:10.3109/01480545.2010.547499
    • Erkekoglu, P., Zeybek, D., Giray, B., Asan, E., Hincal, F., 2011. Reproductive toxicity of di(2-ethylhexyl)phthalate in selenium-supplemented and selenium-deficient rats. Drug Chem. Toxicol., in press. doi:10.3109/01480545.2010.547499.
    • (2011) Drug Chem. Toxicol.
    • Erkekoglu, P.1    Zeybek, D.2    Giray, B.3    Asan, E.4    Hincal, F.5
  • 13
    • 77954511322 scopus 로고    scopus 로고
    • Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells
    • Erkekoglu P., Rachidi W., De Rosa V., Giray B., Favier A., Hincal F. Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells. Free Radical Biol. Med. 2010, 9:559-566.
    • (2010) Free Radical Biol. Med. , vol.9 , pp. 559-566
    • Erkekoglu, P.1    Rachidi, W.2    De Rosa, V.3    Giray, B.4    Favier, A.5    Hincal, F.6
  • 14
    • 77956402478 scopus 로고    scopus 로고
    • Evaluation of cytotoxicity and oxidative DNA damaging effects of di(2-ethylhexyl)phthalate (DEHP) and mono(2-ethylhexyl)phthalate (MEHP) on MA-10 Leydig cells and protection by selenium
    • Erkekoglu P., Rachidi W., Yuzugullu O.G., Giray B., Favier A., Ozturk M., Hincal F. Evaluation of cytotoxicity and oxidative DNA damaging effects of di(2-ethylhexyl)phthalate (DEHP) and mono(2-ethylhexyl)phthalate (MEHP) on MA-10 Leydig cells and protection by selenium. Toxicol. Appl. Pharmacol. 2010, 248:52-62.
    • (2010) Toxicol. Appl. Pharmacol. , vol.248 , pp. 52-62
    • Erkekoglu, P.1    Rachidi, W.2    Yuzugullu, O.G.3    Giray, B.4    Favier, A.5    Ozturk, M.6    Hincal, F.7
  • 15
    • 77954611826 scopus 로고    scopus 로고
    • Molecular mechanisms mediating the effect of mono-(2-ethylhexyl)phthalate on hormone-stimulated steroidogenesis in MA-10 mouse tumor Leydig cells
    • Fan J., Traore K., Li W., Amri H., Huang H., Wu C., Chen H., Zirkin B., Papadopoulos V. Molecular mechanisms mediating the effect of mono-(2-ethylhexyl)phthalate on hormone-stimulated steroidogenesis in MA-10 mouse tumor Leydig cells. Endocrinology 2010, 151:3348-3362.
    • (2010) Endocrinology , vol.151 , pp. 3348-3362
    • Fan, J.1    Traore, K.2    Li, W.3    Amri, H.4    Huang, H.5    Wu, C.6    Chen, H.7    Zirkin, B.8    Papadopoulos, V.9
  • 16
    • 0033571275 scopus 로고    scopus 로고
    • Comparative analysis of p73 and p53 regulation and effector functions
    • Fang L., Lee S.W., Aaronson S.A. Comparative analysis of p73 and p53 regulation and effector functions. J. Cell Biol. 1999, 147:823-830.
    • (1999) J. Cell Biol. , vol.147 , pp. 823-830
    • Fang, L.1    Lee, S.W.2    Aaronson, S.A.3
  • 17
    • 0141757504 scopus 로고    scopus 로고
    • P53 and radiation responses
    • Fei P., El-Deiry W.S. p53 and radiation responses. Oncogene 2003, 22:5774-5783.
    • (2003) Oncogene , vol.22 , pp. 5774-5783
    • Fei, P.1    El-Deiry, W.S.2
  • 18
    • 0032053707 scopus 로고    scopus 로고
    • Oxygen radicals and signaling
    • Finkel T. Oxygen radicals and signaling. Curr. Opin. Cell Biol. 1998, 10:248-253.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 248-253
    • Finkel, T.1
  • 19
    • 20144384882 scopus 로고    scopus 로고
    • Lost in transcription: p21 repression, mechanisms, and consequences
    • Gartel A.L., Radhakrishnan S.K. Lost in transcription: p21 repression, mechanisms, and consequences. Cancer Res. 2005, 65:3980-3985.
    • (2005) Cancer Res. , vol.65 , pp. 3980-3985
    • Gartel, A.L.1    Radhakrishnan, S.K.2
  • 20
    • 0036286837 scopus 로고    scopus 로고
    • Effect of peroxisome proliferators on Leydig cell peripheral-type benzodiazepine receptor gene expression, hormone-stimulated cholesterol transport, and steroidogenesis: role of the peroxisome proliferator-activator receptor alpha
    • Gazouli M., Yao Z.X., Boujrad N., Corton J.C., Culty M., Papadopoulos V. Effect of peroxisome proliferators on Leydig cell peripheral-type benzodiazepine receptor gene expression, hormone-stimulated cholesterol transport, and steroidogenesis: role of the peroxisome proliferator-activator receptor alpha. Endocrinology 2002, 143:2571-2583.
    • (2002) Endocrinology , vol.143 , pp. 2571-2583
    • Gazouli, M.1    Yao, Z.X.2    Boujrad, N.3    Corton, J.C.4    Culty, M.5    Papadopoulos, V.6
  • 21
    • 33645809586 scopus 로고    scopus 로고
    • Selenium protection from DNA damage involves a Ref1/p53/Brca1 protein complex
    • Fischer J.L., Lancia J.K., Mathur A., Smith M.L. Selenium protection from DNA damage involves a Ref1/p53/Brca1 protein complex. Anticancer Res. 2006, 26:899-904.
    • (2006) Anticancer Res. , vol.26 , pp. 899-904
    • Fischer, J.L.1    Lancia, J.K.2    Mathur, A.3    Smith, M.L.4
  • 22
    • 0027361046 scopus 로고
    • Redox modulation of p53 conformation and sequence-specific DNA binding in vitro
    • Hainaut P., Milner J. Redox modulation of p53 conformation and sequence-specific DNA binding in vitro. Cancer Res. 1993, 53:4469-4473.
    • (1993) Cancer Res. , vol.53 , pp. 4469-4473
    • Hainaut, P.1    Milner, J.2
  • 23
    • 0033992478 scopus 로고    scopus 로고
    • P53 and human cancer: the first ten thousand mutations
    • Hainaut P., Hollstein M. p53 and human cancer: the first ten thousand mutations. Adv. Cancer Res. 2000, 77:81-137.
    • (2000) Adv. Cancer Res. , vol.77 , pp. 81-137
    • Hainaut, P.1    Hollstein, M.2
  • 24
    • 0028587756 scopus 로고
    • Oxygen-derived species: their relation to human disease and environmental stress
    • Halliwell B., Cross C.E. Oxygen-derived species: their relation to human disease and environmental stress. Environ. Health Perspect. 1994, 102:5-12.
    • (1994) Environ. Health Perspect. , vol.102 , pp. 5-12
    • Halliwell, B.1    Cross, C.E.2
  • 25
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper J.W., Adami G.R., Wei N., Keyomarsi K., Elledge S.J. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993, 75:805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 27
    • 0031794470 scopus 로고    scopus 로고
    • Lessons from basic research in selenium and cancer prevention
    • Ip C. Lessons from basic research in selenium and cancer prevention. J. Nutr. 1998, 128:1845-1854.
    • (1998) J. Nutr. , vol.128 , pp. 1845-1854
    • Ip, C.1
  • 28
    • 0035865819 scopus 로고    scopus 로고
    • Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms
    • Ishige K., Schubert D., Sagara Y. Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms. Free Radical Biol. Med. 2001, 30:433-446.
    • (2001) Free Radical Biol. Med. , vol.30 , pp. 433-446
    • Ishige, K.1    Schubert, D.2    Sagara, Y.3
  • 29
    • 14644435169 scopus 로고    scopus 로고
    • Antiandrogenic effects in male rats perinatally exposed to a mixture of di(2-ethylhexyl)phthalate and di(2-ethylhexyl)adipate
    • Jarfelt K., Dalgaard M., Hass U., Borch J., Jacobsen H., Ladefoged O. Antiandrogenic effects in male rats perinatally exposed to a mixture of di(2-ethylhexyl)phthalate and di(2-ethylhexyl)adipate. Reprod. Toxicol. 2005, 19:505-515.
    • (2005) Reprod. Toxicol. , vol.19 , pp. 505-515
    • Jarfelt, K.1    Dalgaard, M.2    Hass, U.3    Borch, J.4    Jacobsen, H.5    Ladefoged, O.6
  • 33
    • 8444226001 scopus 로고    scopus 로고
    • Estimated exposure to phthalates in cosmetics and risk assessment
    • Koo H.J., Lee B.M. Estimated exposure to phthalates in cosmetics and risk assessment. J. Toxicol. Environ. Health, Part A 2004, 67:1901-1914.
    • (2004) J. Toxicol. Environ. Health, Part A , vol.67 , pp. 1901-1914
    • Koo, H.J.1    Lee, B.M.2
  • 36
  • 37
    • 0031974830 scopus 로고    scopus 로고
    • Modification of glutamate-induced oxidative stress by lead: the role of extracellular calcium
    • Loikkanen J.J., Naarala J., Savolainen K.M. Modification of glutamate-induced oxidative stress by lead: the role of extracellular calcium. Free Radical Biol. Med. 1998, 4:377-384.
    • (1998) Free Radical Biol. Med. , vol.4 , pp. 377-384
    • Loikkanen, J.J.1    Naarala, J.2    Savolainen, K.M.3
  • 38
    • 33845349483 scopus 로고    scopus 로고
    • Testicular germ cell sensitivity to TRAIL-induced apoptosis is dependent upon p53 expression and is synergistically enhanced by DR5 agonistic antibody treatment
    • McKee C.M., Ye Y., Richburg J.H. Testicular germ cell sensitivity to TRAIL-induced apoptosis is dependent upon p53 expression and is synergistically enhanced by DR5 agonistic antibody treatment. Apoptosis 2006, 11:2237-2250.
    • (2006) Apoptosis , vol.11 , pp. 2237-2250
    • McKee, C.M.1    Ye, Y.2    Richburg, J.H.3
  • 39
    • 0842328577 scopus 로고    scopus 로고
    • NTP center for the evaluation of risks to human reproduction reports on phthalates: addressing the data gaps
    • McKee R.H., Butala J.H., David R.M., Gans G. NTP center for the evaluation of risks to human reproduction reports on phthalates: addressing the data gaps. Reprod. Toxicol. 2004, 18:1-22.
    • (2004) Reprod. Toxicol. , vol.18 , pp. 1-22
    • McKee, R.H.1    Butala, J.H.2    David, R.M.3    Gans, G.4
  • 40
    • 0034635373 scopus 로고    scopus 로고
    • Human and mouse Fas(APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis
    • Munsch D., Watanabe-Fukunaga R., Bourdon J.C., Nagata S., May E., Yonish-Rouach E., Reisdorf P. Human and mouse Fas(APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis. J. Biochem. 2000, 275:3867-3872.
    • (2000) J. Biochem. , vol.275 , pp. 3867-3872
    • Munsch, D.1    Watanabe-Fukunaga, R.2    Bourdon, J.C.3    Nagata, S.4    May, E.5    Yonish-Rouach, E.6    Reisdorf, P.7
  • 41
  • 42
    • 0033834255 scopus 로고    scopus 로고
    • Role of reactive oxygen species in the regulation of physiological functions
    • Nose K. Role of reactive oxygen species in the regulation of physiological functions. Biol. Pharm. Bull. 2000, 23:897-903.
    • (2000) Biol. Pharm. Bull. , vol.23 , pp. 897-903
    • Nose, K.1
  • 43
    • 0034235775 scopus 로고    scopus 로고
    • Localization of antioxidant enzymes and oxidative damage products in normal and malignant prostate epithelium
    • Oberley T.D., Zhong W., Szweda L.I., Oberley L.W. Localization of antioxidant enzymes and oxidative damage products in normal and malignant prostate epithelium. Prostate 2000, 44:144-155.
    • (2000) Prostate , vol.44 , pp. 144-155
    • Oberley, T.D.1    Zhong, W.2    Szweda, L.I.3    Oberley, L.W.4
  • 45
    • 0034521058 scopus 로고    scopus 로고
    • The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat
    • Parks L.G., Ostby J.S., Lambright C.R., Abbott B.D., Klinefelter G.R., Barlow N.J., Gray L.E. The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat. Toxicol. Sci. 2000, 58:339-349.
    • (2000) Toxicol. Sci. , vol.58 , pp. 339-349
    • Parks, L.G.1    Ostby, J.S.2    Lambright, C.R.3    Abbott, B.D.4    Klinefelter, G.R.5    Barlow, N.J.6    Gray, L.E.7
  • 46
    • 0035841951 scopus 로고    scopus 로고
    • Genotoxic and non-genotoxic pathways of p53 induction
    • Pluquet O., Hainaut P. Genotoxic and non-genotoxic pathways of p53 induction. Cancer Lett. 2001, 74:1-15.
    • (2001) Cancer Lett. , vol.74 , pp. 1-15
    • Pluquet, O.1    Hainaut, P.2
  • 47
    • 0029123097 scopus 로고
    • Testicular toxicity of di(2-ethylhexyl)phthalate in developing rats
    • Parmar D., Srivastava S.P., Singh G.B., Seth P.K. Testicular toxicity of di(2-ethylhexyl)phthalate in developing rats. Vet. Hum. Toxicol. 1995, 37:310-313.
    • (1995) Vet. Hum. Toxicol. , vol.37 , pp. 310-313
    • Parmar, D.1    Srivastava, S.P.2    Singh, G.B.3    Seth, P.K.4
  • 49
    • 0022560399 scopus 로고
    • Comparative pharmacokinetics and subacute toxicity of di(2-ethylhexyl)phthalate (DEHP) in rats and marmosets: extrapolation of effects in rodents to man
    • Rhodes C., Orton T.C., Pratt I.S., Batten P.L., Bratt H., Jackson S.J., Elcombe C.R. Comparative pharmacokinetics and subacute toxicity of di(2-ethylhexyl)phthalate (DEHP) in rats and marmosets: extrapolation of effects in rodents to man. Environ. Health Perspect. 1986, 65:299-307.
    • (1986) Environ. Health Perspect. , vol.65 , pp. 299-307
    • Rhodes, C.1    Orton, T.C.2    Pratt, I.S.3    Batten, P.L.4    Bratt, H.5    Jackson, S.J.6    Elcombe, C.R.7
  • 50
    • 0029739518 scopus 로고    scopus 로고
    • Hepatocyte expression of tumor associated aldehyde dehydrogenase (ALDH-3) and p21 Ras following diethylnitrosamine (DEN) initiation and chronic exposure to di(2-ethylhexyl)phthalate (DHEP)
    • Richmond R.E., Carter J.H., Carter H.W., Daniel F.B., Deangelo A.B. Hepatocyte expression of tumor associated aldehyde dehydrogenase (ALDH-3) and p21 Ras following diethylnitrosamine (DEN) initiation and chronic exposure to di(2-ethylhexyl)phthalate (DHEP). Carcinogenesis 1996, 17:1647-1655.
    • (1996) Carcinogenesis , vol.17 , pp. 1647-1655
    • Richmond, R.E.1    Carter, J.H.2    Carter, H.W.3    Daniel, F.B.4    Deangelo, A.B.5
  • 52
    • 0037195158 scopus 로고    scopus 로고
    • Selenomethionine regulation of p53 by a ref1-dependent redox mechanism
    • Seo Y.R., Kelley M.R., Smith M.L. Selenomethionine regulation of p53 by a ref1-dependent redox mechanism. Proc. Natl. Acad. Sci. USA 2002, 99:14548-14553.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 14548-14553
    • Seo, Y.R.1    Kelley, M.R.2    Smith, M.L.3
  • 54
    • 0030598160 scopus 로고    scopus 로고
    • Organic and inorganic selenium compounds inhibit mouse mammary cell growth in vitro by different cellular pathways
    • Sinha R., Said T.K., Medina D. Organic and inorganic selenium compounds inhibit mouse mammary cell growth in vitro by different cellular pathways. Cancer Lett. 1996, 107:277-284.
    • (1996) Cancer Lett. , vol.107 , pp. 277-284
    • Sinha, R.1    Said, T.K.2    Medina, D.3
  • 55
    • 72649102374 scopus 로고    scopus 로고
    • Protection against reactive oxygen species by selenoproteins
    • Steinbrenner H., Sies H. Protection against reactive oxygen species by selenoproteins. Biochim. Biophys. Acta 2009, 1790:1478-1485.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 1478-1485
    • Steinbrenner, H.1    Sies, H.2
  • 56
    • 0344142391 scopus 로고    scopus 로고
    • Selenium compounds have disparate abilities to impose oxidative stress and induce apoptosis
    • Stewart M.S., Spallholz J.E., Neldner K.H., Pence B.C. Selenium compounds have disparate abilities to impose oxidative stress and induce apoptosis. Free Radical Biol. Med. 1999, 26:42-48.
    • (1999) Free Radical Biol. Med. , vol.26 , pp. 42-48
    • Stewart, M.S.1    Spallholz, J.E.2    Neldner, K.H.3    Pence, B.C.4
  • 58
    • 34147210988 scopus 로고    scopus 로고
    • Hydrogen peroxide sensing and signaling
    • Veal E.A., Day A.M., Morgan B.A. Hydrogen peroxide sensing and signaling. Mol. Cell 2007, 26:1-14.
    • (2007) Mol. Cell , vol.26 , pp. 1-14
    • Veal, E.A.1    Day, A.M.2    Morgan, B.A.3
  • 60
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: the cell's response to p53
    • Vousden K.H., Lu X. Live or let die: the cell's response to p53. Nat. Rev. Cancer 2002, 2:594-604.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.