-
2
-
-
50549218525
-
The limited in vitro lifetime of human diploid cell strains
-
Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37 (1965) 614-636
-
(1965)
Exp. Cell Res.
, vol.37
, pp. 614-636
-
-
Hayflick, L.1
-
3
-
-
34548186667
-
Cellular senescence: when bad things happen to good cells
-
Campisi J., and d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat. Rev. Mol. Cell Biol. 8 (2007) 729-740
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 729-740
-
-
Campisi, J.1
d'Adda di Fagagna, F.2
-
4
-
-
0033525558
-
Longevity, stress response, and cancer in aging telomerase-deficient mice
-
Rudolph K.L., Chang S., Lee H.W., Blasco M., Gottlieb G.J., Greider C., and DePinho R.A. Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 96 (1999) 701-712
-
(1999)
Cell
, vol.96
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.W.3
Blasco, M.4
Gottlieb, G.J.5
Greider, C.6
DePinho, R.A.7
-
6
-
-
0035079864
-
Replicative senescence in normal liver, chronic hepatitis C, and hepatocellular carcinomas
-
Paradis V., Youssef N., Dargere D., Ba N., Bonvoust F., Deschatrette J., and Bedossa P. Replicative senescence in normal liver, chronic hepatitis C, and hepatocellular carcinomas. Hum. Pathol. 32 (2001) 327-332
-
(2001)
Hum. Pathol.
, vol.32
, pp. 327-332
-
-
Paradis, V.1
Youssef, N.2
Dargere, D.3
Ba, N.4
Bonvoust, F.5
Deschatrette, J.6
Bedossa, P.7
-
7
-
-
18444374159
-
Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis
-
Wiemann S.U., Satyanarayana A., Tsahuridu M., Tillmann H.L., Zender L., Klempnauer J., Flemming P., Franco S., Blasco M.A., Manns M.P., and Rudolph K.L. Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis. FASEB J. 16 (2002) 935-942
-
(2002)
FASEB J.
, vol.16
, pp. 935-942
-
-
Wiemann, S.U.1
Satyanarayana, A.2
Tsahuridu, M.3
Tillmann, H.L.4
Zender, L.5
Klempnauer, J.6
Flemming, P.7
Franco, S.8
Blasco, M.A.9
Manns, M.P.10
Rudolph, K.L.11
-
8
-
-
2942644356
-
Role of replicative senescence in the progression of fibrosis in hepatitis C virus (HCV) recurrence after liver transplantation
-
Trak-Smayra V., Contreras J., Dondero F., Durand F., Dubois S., Sommacale D., Marcellin P., Belghiti J., Degott C., and Paradis V. Role of replicative senescence in the progression of fibrosis in hepatitis C virus (HCV) recurrence after liver transplantation. Transplantation 77 (2004) 1755-1760
-
(2004)
Transplantation
, vol.77
, pp. 1755-1760
-
-
Trak-Smayra, V.1
Contreras, J.2
Dondero, F.3
Durand, F.4
Dubois, S.5
Sommacale, D.6
Marcellin, P.7
Belghiti, J.8
Degott, C.9
Paradis, V.10
-
9
-
-
34250020201
-
Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
-
El-Serag H.B., and Rudolph K.L. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132 (2007) 2557-2576
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
10
-
-
0034681457
-
Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery
-
Rudolph K.L., Chang S., Millard M., Schreiber-Agus N., and DePinho R.A. Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery. Science 287 (2000) 1253-1258
-
(2000)
Science
, vol.287
, pp. 1253-1258
-
-
Rudolph, K.L.1
Chang, S.2
Millard, M.3
Schreiber-Agus, N.4
DePinho, R.A.5
-
11
-
-
0043026840
-
Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells
-
Satyanarayana A., Wiemann S.U., Buer J., Lauber J., Dittmar K.E., Wüstefeld T., Blasco M.A., Manns M.P., and Rudolph K.L. Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells. EMBO J. 22 (2003) 4003-4013
-
(2003)
EMBO J.
, vol.22
, pp. 4003-4013
-
-
Satyanarayana, A.1
Wiemann, S.U.2
Buer, J.3
Lauber, J.4
Dittmar, K.E.5
Wüstefeld, T.6
Blasco, M.A.7
Manns, M.P.8
Rudolph, K.L.9
-
12
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
Xue W., Zender L., Miething C., Dickins R.A., Hernando E., Krizhanovsky V., Cordon-Cardo C., and Lowe S.W. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 445 (2007) 656-660
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
Dickins, R.A.4
Hernando, E.5
Krizhanovsky, V.6
Cordon-Cardo, C.7
Lowe, S.W.8
-
13
-
-
24944460598
-
Shelterin: the protein complex that shapes and safeguards human telomeres
-
de Lange T. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev. 19 (2005) 2100-2110
-
(2005)
Genes Dev.
, vol.19
, pp. 2100-2110
-
-
de Lange, T.1
-
18
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
d'Adda di Fagagna F., Reaper P.M., Clay-Farrace L., Fiegler H., Carr P., Von Zglinicki T., Saretzki G., Carter N.P., and Jackson S.P. A DNA damage checkpoint response in telomere-initiated senescence. Nature 426 (2003) 194-198
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
d'Adda di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
Saretzki, G.7
Carter, N.P.8
Jackson, S.P.9
-
19
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano M., Lin A.W., McCurrach M.E., Beach D., and Lowe S.W. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88 (1997) 593-602
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
20
-
-
36048965126
-
Breaking news: high-speed race ends in arrest-how oncogenes induce senescence
-
Di Micco R., Fumagalli M., and di Fagagna d.F. Breaking news: high-speed race ends in arrest-how oncogenes induce senescence. Trends Cell Biol. 17 (2007) 529-536
-
(2007)
Trends Cell Biol.
, vol.17
, pp. 529-536
-
-
Di Micco, R.1
Fumagalli, M.2
di Fagagna, d.F.3
-
21
-
-
33748422079
-
Oncogene-induced cell senescence-halting on the road to cancer
-
Mooi W.J., and Peeper D.S. Oncogene-induced cell senescence-halting on the road to cancer. N. Engl. J. Med. 355 (2006) 1037-1046
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 1037-1046
-
-
Mooi, W.J.1
Peeper, D.S.2
-
22
-
-
23244460597
-
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
-
Chen Z., Trotman L.C., Shaffer D., Lin H.K., Dotan Z.A., Niki M., Koutcher J.A., Scher H.I., Ludwig T., Gerald W., Cordon-Cardo C., and Pandolfi P.P. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436 (2005) 725-730
-
(2005)
Nature
, vol.436
, pp. 725-730
-
-
Chen, Z.1
Trotman, L.C.2
Shaffer, D.3
Lin, H.K.4
Dotan, Z.A.5
Niki, M.6
Koutcher, J.A.7
Scher, H.I.8
Ludwig, T.9
Gerald, W.10
Cordon-Cardo, C.11
Pandolfi, P.P.12
-
23
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco R., Fumagalli M., Cicalese A., Piccinin S., Gasparini P., Luise C., Schurra C., Garre' M., Nuciforo P.G., Bensimon A., Maestro R., Pelicci P.G., and d'Adda di Fagagna F. Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 444 (2006) 638-642
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
Piccinin, S.4
Gasparini, P.5
Luise, C.6
Schurra, C.7
Garre', M.8
Nuciforo, P.G.9
Bensimon, A.10
Maestro, R.11
Pelicci, P.G.12
d'Adda di Fagagna, F.13
-
24
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova J., Rezaei N., Liontos M., Karakaidos P., Kletsas D., Issaeva N., Vassiliou L.V., Kolettas E., Niforou K., Zoumpourlis V.C., Takaoka M., Nakagawa H., Tort F., Fugger K., Johansson F., Sehested M., Andersen C.L., Dyrskjot L., Ørntoft T., Lukas J., Kittas C., Helleday T., Halazonetis T.D., Bartek J., and Gorgoulis V.G. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444 (2006) 633-637
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
Rezaei, N.2
Liontos, M.3
Karakaidos, P.4
Kletsas, D.5
Issaeva, N.6
Vassiliou, L.V.7
Kolettas, E.8
Niforou, K.9
Zoumpourlis, V.C.10
Takaoka, M.11
Nakagawa, H.12
Tort, F.13
Fugger, K.14
Johansson, F.15
Sehested, M.16
Andersen, C.L.17
Dyrskjot, L.18
Ørntoft, T.19
Lukas, J.20
Kittas, C.21
Helleday, T.22
Halazonetis, T.D.23
Bartek, J.24
Gorgoulis, V.G.25
more..
-
25
-
-
43049163718
-
Free radicals and senescence
-
Lu T., and Finkel T. Free radicals and senescence. Exp. Cell Res. 314 (2008) 1918-1922
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 1918-1922
-
-
Lu, T.1
Finkel, T.2
-
26
-
-
34548148201
-
Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?
-
Giorgio M., Trinei M., Migliaccio E., and Pelicci P.G. Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?. Nat. Rev. Mol. Cell Biol. 8 (2007) 722-728
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 722-728
-
-
Giorgio, M.1
Trinei, M.2
Migliaccio, E.3
Pelicci, P.G.4
-
28
-
-
0029127226
-
Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence?
-
von Zglinicki T., Saretzki G., Döcke W., and Lotze C. Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence?. Exp. Cell Res. 220 (1995) 186-193
-
(1995)
Exp. Cell Res.
, vol.220
, pp. 186-193
-
-
von Zglinicki, T.1
Saretzki, G.2
Döcke, W.3
Lotze, C.4
-
29
-
-
0033583242
-
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
-
Lee A.C., Fenster B.E., Ito H., Takeda K., Bae N.S., Hirai T., Yu Z.X., Ferrans V.J., Howard B.H., and Finkel T. Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. J. Biol. Chem. 274 (1999) 7936-7940
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7936-7940
-
-
Lee, A.C.1
Fenster, B.E.2
Ito, H.3
Takeda, K.4
Bae, N.S.5
Hirai, T.6
Yu, Z.X.7
Ferrans, V.J.8
Howard, B.H.9
Finkel, T.10
-
30
-
-
42949129074
-
Many roads lead to oncogene-induced senescence
-
Courtois-Cox S., Jones S.L., and Cichowski K. Many roads lead to oncogene-induced senescence. Oncogene 27 (2008) 2801-2809
-
(2008)
Oncogene
, vol.27
, pp. 2801-2809
-
-
Courtois-Cox, S.1
Jones, S.L.2
Cichowski, K.3
-
31
-
-
34249028642
-
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence
-
Passos J.F., Saretzki G., Ahmed S., Nelson G., Richter T., Peters H., Wappler I., Birket M.J., Harold G., Schaeuble K., Birch-Machin M.A., Kirkwood T.B., and von Zglinicki T. Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence. PLoS Biol. 5 (2007) e110
-
(2007)
PLoS Biol.
, vol.5
-
-
Passos, J.F.1
Saretzki, G.2
Ahmed, S.3
Nelson, G.4
Richter, T.5
Peters, H.6
Wappler, I.7
Birket, M.J.8
Harold, G.9
Schaeuble, K.10
Birch-Machin, M.A.11
Kirkwood, T.B.12
von Zglinicki, T.13
-
32
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K., Hirao A., Arai F., Takubo K., Matsuoka S., Miyamoto K., Ohmura M., Naka K., Hosokawa K., Ikeda Y., and Suda T. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat. Med. 12 (2006) 446-451
-
(2006)
Nat. Med.
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
Miyamoto, K.6
Ohmura, M.7
Naka, K.8
Hosokawa, K.9
Ikeda, Y.10
Suda, T.11
-
33
-
-
2442511752
-
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a) but not p16(INK4a)
-
Herbig U., Jobling W.A., Chen B.P., Chen D.J., and Sedivy J.M. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a) but not p16(INK4a). Mol. Cell. 14 (2004) 501-513
-
(2004)
Mol. Cell.
, vol.14
, pp. 501-513
-
-
Herbig, U.1
Jobling, W.A.2
Chen, B.P.3
Chen, D.J.4
Sedivy, J.M.5
-
34
-
-
33846128155
-
The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence
-
Mallette F.A., Gaumont-Leclerc M.F., and Ferbeyre G. The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence. Genes Dev. 21 (2007) 43-48
-
(2007)
Genes Dev.
, vol.21
, pp. 43-48
-
-
Mallette, F.A.1
Gaumont-Leclerc, M.F.2
Ferbeyre, G.3
-
35
-
-
33747587608
-
Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all
-
Gil J., and Peters G. Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all. Nat. Rev. Mol. Cell Biol. 7 (2006) 667-677
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 667-677
-
-
Gil, J.1
Peters, G.2
-
36
-
-
0030477686
-
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
-
Alcorta D.A., Xiong Y., Phelps D., Hannon G., Beach D., and Barrett J.C. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proc. Natl. Acad. Sci. U S A 93 (1996) 13742-13747
-
(1996)
Proc. Natl. Acad. Sci. U S A
, vol.93
, pp. 13742-13747
-
-
Alcorta, D.A.1
Xiong, Y.2
Phelps, D.3
Hannon, G.4
Beach, D.5
Barrett, J.C.6
-
37
-
-
0030612349
-
Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging
-
Zindy F., Quelle D.E., Roussel M.F., and Sherr C.J. Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging. Oncogene 15 (1997) 203-211
-
(1997)
Oncogene
, vol.15
, pp. 203-211
-
-
Zindy, F.1
Quelle, D.E.2
Roussel, M.F.3
Sherr, C.J.4
-
38
-
-
0034704916
-
Defects in TGF-beta signaling overcome senescence of mouse keratinocytes expressing v-Ha-ras
-
Tremain R., Marko M., Kinnimulki V., Ueno H., Bottinger E., and Glick A. Defects in TGF-beta signaling overcome senescence of mouse keratinocytes expressing v-Ha-ras. Oncogene 19 (2000) 1698-1709
-
(2000)
Oncogene
, vol.19
, pp. 1698-1709
-
-
Tremain, R.1
Marko, M.2
Kinnimulki, V.3
Ueno, H.4
Bottinger, E.5
Glick, A.6
-
39
-
-
38849168162
-
Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7
-
Wajapeyee N., Serra R.W., Zhu X., Mahalingam M., and Green M.R. Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell 132 (2008) 363-374
-
(2008)
Cell
, vol.132
, pp. 363-374
-
-
Wajapeyee, N.1
Serra, R.W.2
Zhu, X.3
Mahalingam, M.4
Green, M.R.5
-
40
-
-
44649120132
-
Chemokine signaling via the CXCR2 receptor reinforces senescence
-
Acosta J.C., O'Loghlen A., Banito A., Guijarro M.V., Augert A., Raguz S., Fumagalli M., Da Costa M., Brown C., Popov N., Takatsu Y., Melamed J., d'Adda di Fagagna F., Bernard D., Hernando E., and Gil J. Chemokine signaling via the CXCR2 receptor reinforces senescence. Cell 133 (2008) 1006-1018
-
(2008)
Cell
, vol.133
, pp. 1006-1018
-
-
Acosta, J.C.1
O'Loghlen, A.2
Banito, A.3
Guijarro, M.V.4
Augert, A.5
Raguz, S.6
Fumagalli, M.7
Da Costa, M.8
Brown, C.9
Popov, N.10
Takatsu, Y.11
Melamed, J.12
d'Adda di Fagagna, F.13
Bernard, D.14
Hernando, E.15
Gil, J.16
-
41
-
-
44649101304
-
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
-
Kuilman T., Michaloglou C., Vredeveld L.C., Douma S., van Doorn R., Desmet C.J., Aarden L.A., Mooi W.J., and Peeper D.S. Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 133 (2008) 1019-1031
-
(2008)
Cell
, vol.133
, pp. 1019-1031
-
-
Kuilman, T.1
Michaloglou, C.2
Vredeveld, L.C.3
Douma, S.4
van Doorn, R.5
Desmet, C.J.6
Aarden, L.A.7
Mooi, W.J.8
Peeper, D.S.9
-
42
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
el-Deiry W.S., Tokino T., Velculescu V.E., Levy D.B., Parsons R., Trent J.M., Lin D., Mercer W.E., Kinzler K.W., and Vogelstein B. WAF1, a potential mediator of p53 tumor suppression. Cell 75 (1993) 817-825
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
el-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
43
-
-
44349136891
-
Telomere dysfunction and tumor suppression: the senescence connection
-
Deng Y., Chan S.S., and Chang S. Telomere dysfunction and tumor suppression: the senescence connection. Nat. Rev. Cancer 8 (2008) 450-458
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 450-458
-
-
Deng, Y.1
Chan, S.S.2
Chang, S.3
-
44
-
-
0033528830
-
p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53
-
Fang L., Igarashi M., Leung J., Sugrue M.M., Lee S.W., and Aaronson S.A. p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53. Oncogene 18 (1999) 2789-2797
-
(1999)
Oncogene
, vol.18
, pp. 2789-2797
-
-
Fang, L.1
Igarashi, M.2
Leung, J.3
Sugrue, M.M.4
Lee, S.W.5
Aaronson, S.A.6
-
45
-
-
33748047128
-
RB and cell cycle progression
-
Giacinti C., and Giordano A. RB and cell cycle progression. Oncogene 25 (2006) 5220-5227
-
(2006)
Oncogene
, vol.25
, pp. 5220-5227
-
-
Giacinti, C.1
Giordano, A.2
-
46
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita M., Nunez S., Heard E., Lin A.W., Hearn S.A., Spector D.L., Hannon G.J., and Lowe S.W. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113 (2003) 703-716
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
Lin, A.W.4
Hearn, S.A.5
Spector, D.L.6
Hannon, G.J.7
Lowe, S.W.8
-
47
-
-
19944427674
-
Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA
-
Zhang R., Poustovoitov M.V., Ye X., Santos H.A., Chen W., Daganzo S.M., Erzberger J.P., Serebriiskii I.G., Canutescu A.A., Dunbrack R.L., Pehrson J.R., Berger J.M., Kaufman P.D., and Adams P.D. Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA. Dev. Cell 8 (2005) 19-30
-
(2005)
Dev. Cell
, vol.8
, pp. 19-30
-
-
Zhang, R.1
Poustovoitov, M.V.2
Ye, X.3
Santos, H.A.4
Chen, W.5
Daganzo, S.M.6
Erzberger, J.P.7
Serebriiskii, I.G.8
Canutescu, A.A.9
Dunbrack, R.L.10
Pehrson, J.R.11
Berger, J.M.12
Kaufman, P.D.13
Adams, P.D.14
-
48
-
-
33746752125
-
A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation
-
Narita M., Narita M., Krizhanovsky V., Nunez S., Chicas A., Hearn S.A., Myers M.P., and Lowe S.W. A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation. Cell 126 (2006) 503-514
-
(2006)
Cell
, vol.126
, pp. 503-514
-
-
Narita, M.1
Narita, M.2
Krizhanovsky, V.3
Nunez, S.4
Chicas, A.5
Hearn, S.A.6
Myers, M.P.7
Lowe, S.W.8
-
49
-
-
34147182401
-
Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging
-
Adams P.D. Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging. Gene 397 (2007) 84-93
-
(2007)
Gene
, vol.397
, pp. 84-93
-
-
Adams, P.D.1
-
50
-
-
0036164074
-
Telomere lengths are characteristic in each human individual
-
Takubo K., Izumiyama-Shimomura N., Honma N., Sawabe M., Arai T., Kato M., Oshimura M., and Nakamura K. Telomere lengths are characteristic in each human individual. Exp. Gerontol. 37 (2002) 523-531
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 523-531
-
-
Takubo, K.1
Izumiyama-Shimomura, N.2
Honma, N.3
Sawabe, M.4
Arai, T.5
Kato, M.6
Oshimura, M.7
Nakamura, K.8
-
51
-
-
0034192192
-
Telomere reduction in human liver tissues with age and chronic inflammation
-
Aikata H., Takaishi H., Kawakami Y., Takahashi S., Kitamoto M., Nakanishi T., Nakamura Y., Shimamoto F., Kajiyama G., and Ide T. Telomere reduction in human liver tissues with age and chronic inflammation. Exp. Cell Res. 256 (2000) 578-582
-
(2000)
Exp. Cell Res.
, vol.256
, pp. 578-582
-
-
Aikata, H.1
Takaishi, H.2
Kawakami, Y.3
Takahashi, S.4
Kitamoto, M.5
Nakanishi, T.6
Nakamura, Y.7
Shimamoto, F.8
Kajiyama, G.9
Ide, T.10
-
52
-
-
39549088700
-
Susceptibility of chimeric mice with livers repopulated by serially subcultured human hepatocytes to hepatitis B virus
-
Utoh R., Tateno C., Yamasaki C., Hiraga N., Kataoka M., Shimada T., Chayama K., and Yoshizato K. Susceptibility of chimeric mice with livers repopulated by serially subcultured human hepatocytes to hepatitis B virus. Hepatology 47 (2008) 435-446
-
(2008)
Hepatology
, vol.47
, pp. 435-446
-
-
Utoh, R.1
Tateno, C.2
Yamasaki, C.3
Hiraga, N.4
Kataoka, M.5
Shimada, T.6
Chayama, K.7
Yoshizato, K.8
-
53
-
-
0029929999
-
Relationship between hepatocyte proliferative activity and liver functional reserve in human cirrhosis
-
Delhaye M., Louis H., Degraef C., Le Moine O., Devière J., Gulbis B., Jacobovitz D., Adler M., and Galand P. Relationship between hepatocyte proliferative activity and liver functional reserve in human cirrhosis. Hepatology 23 (1996) 1003-1011
-
(1996)
Hepatology
, vol.23
, pp. 1003-1011
-
-
Delhaye, M.1
Louis, H.2
Degraef, C.3
Le Moine, O.4
Devière, J.5
Gulbis, B.6
Jacobovitz, D.7
Adler, M.8
Galand, P.9
-
54
-
-
0037687519
-
Human epithelial cell immortalization as a step in carcinogenesis
-
Stampfer M.R., and Yaswen P. Human epithelial cell immortalization as a step in carcinogenesis. Cancer Lett. 194 (2003) 199-208
-
(2003)
Cancer Lett.
, vol.194
, pp. 199-208
-
-
Stampfer, M.R.1
Yaswen, P.2
-
55
-
-
0037308362
-
Telomerase reconstitution immortalized human fetal hepatocytes without disrupting their differentiation potential
-
Wege H., Le H.T., Chui M.S., Lui L., Wu J., Giri G., Malhi H., Sappal B.S., Kumaran V., Gupta S., and Zern M.A. Telomerase reconstitution immortalized human fetal hepatocytes without disrupting their differentiation potential. Gastroenterology 124 (2003) 432-444
-
(2003)
Gastroenterology
, vol.124
, pp. 432-444
-
-
Wege, H.1
Le, H.T.2
Chui, M.S.3
Lui, L.4
Wu, J.5
Giri, G.6
Malhi, H.7
Sappal, B.S.8
Kumaran, V.9
Gupta, S.10
Zern, M.A.11
-
56
-
-
20144389189
-
The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo
-
Lechel A., Satyanarayana A., Ju Z., Plentz R.R., Schaetzlein S., Rudolph C., Wilkens L., Wiemann S.U., Saretzki G., Malek N.P., Manns M.P., Buer J., and Rudolph K.L. The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo. EMBO Rep. 6 (2005) 275-281
-
(2005)
EMBO Rep.
, vol.6
, pp. 275-281
-
-
Lechel, A.1
Satyanarayana, A.2
Ju, Z.3
Plentz, R.R.4
Schaetzlein, S.5
Rudolph, C.6
Wilkens, L.7
Wiemann, S.U.8
Saretzki, G.9
Malek, N.P.10
Manns, M.P.11
Buer, J.12
Rudolph, K.L.13
-
57
-
-
33749369156
-
Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication
-
Lazzerini Denchi E., Celli G., and de Lange T. Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication. Genes Dev. 20 (2006) 2648-2653
-
(2006)
Genes Dev.
, vol.20
, pp. 2648-2653
-
-
Lazzerini Denchi, E.1
Celli, G.2
de Lange, T.3
-
59
-
-
42949086433
-
Cellular and molecular mechanisms of liver injury
-
Malhi H., and Gores G.J. Cellular and molecular mechanisms of liver injury. Gastroenterology 134 (2008) 1641-1654
-
(2008)
Gastroenterology
, vol.134
, pp. 1641-1654
-
-
Malhi, H.1
Gores, G.J.2
-
60
-
-
40049097359
-
Liver cirrhosis
-
Schuppan D., and Afdhal N.H. Liver cirrhosis. Lancet 371 (2008) 838-851
-
(2008)
Lancet
, vol.371
, pp. 838-851
-
-
Schuppan, D.1
Afdhal, N.H.2
-
61
-
-
36749092354
-
Hepatitis C virus: from oxygen free radicals to hepatocellular carcinoma
-
Farinati F., Cardin R., Bortolami M., Burra P., Russo F.P., Rugge M., Guido M., Sergio A., and Naccarato R. Hepatitis C virus: from oxygen free radicals to hepatocellular carcinoma. J. Viral Hepat. 14 (2007) 821-829
-
(2007)
J. Viral Hepat.
, vol.14
, pp. 821-829
-
-
Farinati, F.1
Cardin, R.2
Bortolami, M.3
Burra, P.4
Russo, F.P.5
Rugge, M.6
Guido, M.7
Sergio, A.8
Naccarato, R.9
-
63
-
-
0028339240
-
Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human livers with chronic hepatitis
-
Shimoda R., Nagashima M., Sakamoto M., Yamaguchi N., Hirohashi S., Yokota J., and Kasai H. Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human livers with chronic hepatitis. Cancer Res. 54 (1994) 3171-3172
-
(1994)
Cancer Res.
, vol.54
, pp. 3171-3172
-
-
Shimoda, R.1
Nagashima, M.2
Sakamoto, M.3
Yamaguchi, N.4
Hirohashi, S.5
Yokota, J.6
Kasai, H.7
-
64
-
-
11144265902
-
Upregulation of DNA repair genes in active cirrhosis associated with hepatocellular carcinoma
-
Zindy P., Andrieux L., Bonnier D., Musso O., Langouët S., Campion J.P., Turlin B., Clément B., and Théret N. Upregulation of DNA repair genes in active cirrhosis associated with hepatocellular carcinoma. FEBS Lett. 579 (2005) 95-99
-
(2005)
FEBS Lett.
, vol.579
, pp. 95-99
-
-
Zindy, P.1
Andrieux, L.2
Bonnier, D.3
Musso, O.4
Langouët, S.5
Campion, J.P.6
Turlin, B.7
Clément, B.8
Théret, N.9
-
65
-
-
34247400156
-
Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis
-
Plentz R.R., Park Y.N., Lechel A., Kim H., Nellessen F., Langkopf B.H., Wilkens L., Destro A., Fiamengo B., Manns M.P., Roncalli M., and Rudolph K.L. Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis. Hepatology 45 (2007) 968-976
-
(2007)
Hepatology
, vol.45
, pp. 968-976
-
-
Plentz, R.R.1
Park, Y.N.2
Lechel, A.3
Kim, H.4
Nellessen, F.5
Langkopf, B.H.6
Wilkens, L.7
Destro, A.8
Fiamengo, B.9
Manns, M.P.10
Roncalli, M.11
Rudolph, K.L.12
-
66
-
-
18444369018
-
Methylation framework of cell cycle gene inhibitors in cirrhosis and associated hepatocellular carcinoma
-
Roncalli M., Bianchi P., Bruni B., Laghi L., Destro A., Di Gioia S., Gennari L., Tommasini M., Malesci A., and Coggi G. Methylation framework of cell cycle gene inhibitors in cirrhosis and associated hepatocellular carcinoma. Hepatology 36 (2002) 427-432
-
(2002)
Hepatology
, vol.36
, pp. 427-432
-
-
Roncalli, M.1
Bianchi, P.2
Bruni, B.3
Laghi, L.4
Destro, A.5
Di Gioia, S.6
Gennari, L.7
Tommasini, M.8
Malesci, A.9
Coggi, G.10
-
67
-
-
0032847563
-
Genetic aspects of hepatocellular carcinogenesis
-
Ozturk M. Genetic aspects of hepatocellular carcinogenesis. Semin. Liver Dis. 19 (1999) 235-242
-
(1999)
Semin. Liver Dis.
, vol.19
, pp. 235-242
-
-
Ozturk, M.1
-
68
-
-
34047216406
-
p53 alterations in human cancer: more questions than answers
-
Soussi T. p53 alterations in human cancer: more questions than answers. Oncogene 26 (2007) 2145-2156
-
(2007)
Oncogene
, vol.26
, pp. 2145-2156
-
-
Soussi, T.1
-
69
-
-
0038505659
-
Alterations of RB1, p53 and Wnt pathways in Hepatocellular carcinomas associated with HCV, HBV and alcoholic liver cirrhosis
-
Edamoto Y., Hara A., Biernat W., Terracciano L., Cathamos G., Riehle H.M., Matsuda M., Fuji H., Scoazec J.M., and Ohgaki H. Alterations of RB1, p53 and Wnt pathways in Hepatocellular carcinomas associated with HCV, HBV and alcoholic liver cirrhosis. Int. J. Cancer 106 (2003) 334-341
-
(2003)
Int. J. Cancer
, vol.106
, pp. 334-341
-
-
Edamoto, Y.1
Hara, A.2
Biernat, W.3
Terracciano, L.4
Cathamos, G.5
Riehle, H.M.6
Matsuda, M.7
Fuji, H.8
Scoazec, J.M.9
Ohgaki, H.10
-
70
-
-
0029019717
-
Telomerase activity in human liver tissues: Comparison between chronic liver disease and hepatocellular carcinomas
-
Tahara H., Nakanishi T., Kitamoto M., Nakashio R., Shay J.W., Tahara E., Kajiyama G., and Ide T. Telomerase activity in human liver tissues: Comparison between chronic liver disease and hepatocellular carcinomas. Cancer Res. 55 (1995) 2734-2736
-
(1995)
Cancer Res.
, vol.55
, pp. 2734-2736
-
-
Tahara, H.1
Nakanishi, T.2
Kitamoto, M.3
Nakashio, R.4
Shay, J.W.5
Tahara, E.6
Kajiyama, G.7
Ide, T.8
-
71
-
-
0031041024
-
Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease
-
Kojima H., Yokosuka O., Imazeki F., Saisho H., and Omata M. Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease. Gastroenterology 112 (1997) 493-500
-
(1997)
Gastroenterology
, vol.112
, pp. 493-500
-
-
Kojima, H.1
Yokosuka, O.2
Imazeki, F.3
Saisho, H.4
Omata, M.5
-
72
-
-
17344363008
-
Telomerase activation by hTERT in human normal fibroblasts and hepatocellular carcinomas
-
Nakayama J., Tahara H., Tahara E., Saito M., Ito K., Nakamura H., Nakanishi T., Tahara E., Ide T., and Ishikawa F. Telomerase activation by hTERT in human normal fibroblasts and hepatocellular carcinomas. Nat. Genet. 18 (1998) 65-68
-
(1998)
Nat. Genet.
, vol.18
, pp. 65-68
-
-
Nakayama, J.1
Tahara, H.2
Tahara, E.3
Saito, M.4
Ito, K.5
Nakamura, H.6
Nakanishi, T.7
Tahara, E.8
Ide, T.9
Ishikawa, F.10
-
73
-
-
0035959742
-
Identification of human cancer-related genes by naturally occurring Hepatitis B Virus DNA tagging
-
Gozuacik D., Murakami Y., Saigo K., Chami M., Mugnier C., Lagorce D., Okanoue T., Urashima T., Bréchot C., and Paterlini-Bréchot P. Identification of human cancer-related genes by naturally occurring Hepatitis B Virus DNA tagging. Oncogene 20 (2001) 6233-6240
-
(2001)
Oncogene
, vol.20
, pp. 6233-6240
-
-
Gozuacik, D.1
Murakami, Y.2
Saigo, K.3
Chami, M.4
Mugnier, C.5
Lagorce, D.6
Okanoue, T.7
Urashima, T.8
Bréchot, C.9
Paterlini-Bréchot, P.10
-
74
-
-
0042169025
-
Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms
-
Horikawa I., and Barrett JC. Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms. Carcinogenesis 24 (2003) 1167-1176
-
(2003)
Carcinogenesis
, vol.24
, pp. 1167-1176
-
-
Horikawa, I.1
Barrett, JC.2
-
75
-
-
22644435919
-
Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas
-
Murakami Y., Saigo K., Takashima H., Minami M., Okanoue T., Bréchot C., and Paterlini-Bréchot P. Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas. Gut 54 (2005) 1162-1168
-
(2005)
Gut
, vol.54
, pp. 1162-1168
-
-
Murakami, Y.1
Saigo, K.2
Takashima, H.3
Minami, M.4
Okanoue, T.5
Bréchot, C.6
Paterlini-Bréchot, P.7
-
76
-
-
28044439605
-
Upregulation of human telomerase reverse transcriptase mRNA expression by in vitro transfection of hepatitis B virus X gene into human hepatocarcinoma and cholangiocarcinoma cells
-
Qu Z.L., Zou S.Q., Cui N.Q., Wu X.Z., Qin M.F., Kong D., and Zhou Z.L. Upregulation of human telomerase reverse transcriptase mRNA expression by in vitro transfection of hepatitis B virus X gene into human hepatocarcinoma and cholangiocarcinoma cells. World J. Gastroenterol. 11 (2005) 5627-5632
-
(2005)
World J. Gastroenterol.
, vol.11
, pp. 5627-5632
-
-
Qu, Z.L.1
Zou, S.Q.2
Cui, N.Q.3
Wu, X.Z.4
Qin, M.F.5
Kong, D.6
Zhou, Z.L.7
-
77
-
-
33847241218
-
In vitro transfection of the hepatitis B virus PreS2 gene into the human hepatocarcinoma cell line HepG2 induces upregulation of human telomerase reverse transcriptase
-
Liu H., Luan F., Ju Y., Shen H., Gao L., Wang X., Liu S., Zhang L., Sun W., and Ma C. In vitro transfection of the hepatitis B virus PreS2 gene into the human hepatocarcinoma cell line HepG2 induces upregulation of human telomerase reverse transcriptase. Biochem. Biophys. Res. Commun. 355 (2007) 379-384
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.355
, pp. 379-384
-
-
Liu, H.1
Luan, F.2
Ju, Y.3
Shen, H.4
Gao, L.5
Wang, X.6
Liu, S.7
Zhang, L.8
Sun, W.9
Ma, C.10
-
78
-
-
1842828901
-
On the road to immortality: hTERT upregulation in cancer cells
-
Janknecht R. On the road to immortality: hTERT upregulation in cancer cells. FEBS Lett. 564 (2004) 9-13
-
(2004)
FEBS Lett.
, vol.564
, pp. 9-13
-
-
Janknecht, R.1
-
79
-
-
0031054261
-
Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis
-
Miura N., Horikawa I., Nishimoto A., Ohmura H., Ito H., Hirohashi S., Shay J.W., and Oshimura M. Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis. Cancer Genet. Cytogenet. 93 (1997) 56-62
-
(1997)
Cancer Genet. Cytogenet.
, vol.93
, pp. 56-62
-
-
Miura, N.1
Horikawa, I.2
Nishimoto, A.3
Ohmura, H.4
Ito, H.5
Hirohashi, S.6
Shay, J.W.7
Oshimura, M.8
-
80
-
-
44949194700
-
Telomeric 3' overhangs in chronic HBV-related hepatitis and hepatocellular carcinoma
-
Lee J.E., Oh B.K., Choi J., and Park Y.N. Telomeric 3' overhangs in chronic HBV-related hepatitis and hepatocellular carcinoma. Int. J. Cancer 123 (2008) 264-272
-
(2008)
Int. J. Cancer
, vol.123
, pp. 264-272
-
-
Lee, J.E.1
Oh, B.K.2
Choi, J.3
Park, Y.N.4
-
81
-
-
11144227269
-
Up-regulation of telomere-binding proteins, TRF1, TRF2, and TIN2 is related to telomere shortening during human multistep hepatocarcinogenesis
-
Oh B.K., Kim Y.J., Park C., and Park Y.N. Up-regulation of telomere-binding proteins, TRF1, TRF2, and TIN2 is related to telomere shortening during human multistep hepatocarcinogenesis. Am. J. Pathol. 166 (2005) 73-80
-
(2005)
Am. J. Pathol.
, vol.166
, pp. 73-80
-
-
Oh, B.K.1
Kim, Y.J.2
Park, C.3
Park, Y.N.4
-
82
-
-
4043124073
-
Telomeres and Telomerase: a Dual role in hepatocarcinogenesis
-
Satyanarayana A., Manns M.P., and Rudolph K.L. Telomeres and Telomerase: a Dual role in hepatocarcinogenesis. Hepatology 40 (2004) 276-283
-
(2004)
Hepatology
, vol.40
, pp. 276-283
-
-
Satyanarayana, A.1
Manns, M.P.2
Rudolph, K.L.3
-
83
-
-
34247268524
-
Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease
-
Lechel A., Holstege H., Begus Y., Schienke A., Kamino K., Lehmann U., Kubicka S., Schirmacher P., Jonkers J., and Rudolph K.L. Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease. Gastroenterology 132 (2007) 1465-1475
-
(2007)
Gastroenterology
, vol.132
, pp. 1465-1475
-
-
Lechel, A.1
Holstege, H.2
Begus, Y.3
Schienke, A.4
Kamino, K.5
Lehmann, U.6
Kubicka, S.7
Schirmacher, P.8
Jonkers, J.9
Rudolph, K.L.10
-
84
-
-
0033614998
-
Creation of human tumor cells with defined genetic elements
-
Hahn W.C., Counter C.M., Lundberg A.S., Beijersbergen R.L., Brooks M.W., and Weinberg R.A. Creation of human tumor cells with defined genetic elements. Nature 400 (1999) 464-468
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
Beijersbergen, R.L.4
Brooks, M.W.5
Weinberg, R.A.6
-
85
-
-
2342570379
-
Hallmarks of senescence in carcinogenesis and cancer therapy
-
Shay J.W., and Roninson I.B. Hallmarks of senescence in carcinogenesis and cancer therapy. Oncogene 23 (2004) 2919-2933
-
(2004)
Oncogene
, vol.23
, pp. 2919-2933
-
-
Shay, J.W.1
Roninson, I.B.2
-
86
-
-
23244447893
-
Tumour biology: senescence in premalignant tumours
-
Collado M., Gil J., Efeyan A., Guerra C., Schuhmacher A.J., Barradas M., Benguría A., Zaballos A., Flores J.M., Barbacid M., Beach D., and Serrano M. Tumour biology: senescence in premalignant tumours. Nature 436 (2005) 642
-
(2005)
Nature
, vol.436
, pp. 642
-
-
Collado, M.1
Gil, J.2
Efeyan, A.3
Guerra, C.4
Schuhmacher, A.J.5
Barradas, M.6
Benguría, A.7
Zaballos, A.8
Flores, J.M.9
Barbacid, M.10
Beach, D.11
Serrano, M.12
-
87
-
-
23244461708
-
Oncogene-induced senescence as an initial barrier in lymphoma development
-
Braig M., Lee S., Loddenkemper C., Rudolph C., Peters A.H., Schlegelberger B., Stein H., Dörken B., Jenuwein T., and Schmitt C.A. Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 436 (2005) 660-665
-
(2005)
Nature
, vol.436
, pp. 660-665
-
-
Braig, M.1
Lee, S.2
Loddenkemper, C.3
Rudolph, C.4
Peters, A.H.5
Schlegelberger, B.6
Stein, H.7
Dörken, B.8
Jenuwein, T.9
Schmitt, C.A.10
-
88
-
-
23244447037
-
BRAFE600-associated senescence-like cell cycle arrest of human naevi
-
Michaloglou C., Vredeveld L.C., Soengas M.S., Denoyelle C., Kuilman T., van der Horst C.M., Majoor D.M., Shay J.W., Mooi W.J., and Peeper D.S. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 436 (2005) 720-724
-
(2005)
Nature
, vol.436
, pp. 720-724
-
-
Michaloglou, C.1
Vredeveld, L.C.2
Soengas, M.S.3
Denoyelle, C.4
Kuilman, T.5
van der Horst, C.M.6
Majoor, D.M.7
Shay, J.W.8
Mooi, W.J.9
Peeper, D.S.10
-
89
-
-
0034634759
-
5-Aza-2'-deoxycytidine leads to down-regulation of aberrant p16 RNA transcripts and restores the functional retinoblastoma protein pathway in hepatocellular carcinoma cell lines
-
Suh S.I., Pyun H.Y., Cho J.W., Baek W.K., Park J.B., Kwon T., Park J.W., Suh M.H., and Carson D.A. 5-Aza-2'-deoxycytidine leads to down-regulation of aberrant p16 RNA transcripts and restores the functional retinoblastoma protein pathway in hepatocellular carcinoma cell lines. Cancer Lett. 160 (2000) 81-88
-
(2000)
Cancer Lett.
, vol.160
, pp. 81-88
-
-
Suh, S.I.1
Pyun, H.Y.2
Cho, J.W.3
Baek, W.K.4
Park, J.B.5
Kwon, T.6
Park, J.W.7
Suh, M.H.8
Carson, D.A.9
-
90
-
-
34548771087
-
Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation
-
Wu C.H., van Riggelen J., Yetil A., Fan A.C., Bachireddy P., and Felsher D.W. Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation. Proc. Natl. Acad. Sci. USA 104 (2007) 13028-13033
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 13028-13033
-
-
Wu, C.H.1
van Riggelen, J.2
Yetil, A.3
Fan, A.C.4
Bachireddy, P.5
Felsher, D.W.6
-
91
-
-
33144465731
-
Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells
-
Ozturk N., Erdal E., Mumcuoglu M., Akcali K.C., Yalcin O., Senturk S., Arslan-Ergul A., Gur B., Yulug I., Cetin-Atalay R., Yakicier C., Yagci T., Tez M., and Ozturk M. Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells. Proc. Natl. Acad. Sci. USA 103 (2006) 2178-2183
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 2178-2183
-
-
Ozturk, N.1
Erdal, E.2
Mumcuoglu, M.3
Akcali, K.C.4
Yalcin, O.5
Senturk, S.6
Arslan-Ergul, A.7
Gur, B.8
Yulug, I.9
Cetin-Atalay, R.10
Yakicier, C.11
Yagci, T.12
Tez, M.13
Ozturk, M.14
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