-
1
-
-
60249083789
-
Evolving molecular classification by genomic and proteomic biomarkers in colorectal cancer: Potential implications for the surgical oncologist
-
Soreide K, Nedrebo BS, Knapp JC, Glomsaker TB, Soreide JA, Korner H. (2009) Evolving molecular classification by genomic and proteomic biomarkers in colorectal cancer: potential implications for the surgical oncologist. Surg Oncol 18:31-50.
-
(2009)
Surg Oncol
, vol.18
, pp. 31-50
-
-
Soreide, K.1
Nedrebo, B.S.2
Knapp, J.C.3
Glomsaker, T.B.4
Soreide, J.A.5
Korner, H.6
-
2
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B. (1990) A genetic model for colorectal tumorigenesis. Cell 61:759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
3
-
-
0037047057
-
Mutations in APC, Kirsten-ras, and p53 - Alternative genetic pathways to colorectal cancer
-
Smith G, Carey FA, Beattie J, Wilkie MJ, Lightfoot TJ, Coxhead J et al. (2002) Mutations in APC, Kirsten-ras, and p53 - alternative genetic pathways to colorectal cancer. Proc Natl Acad Sci U S A 99:9433-9438.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 9433-9438
-
-
Smith, G.1
Carey, F.A.2
Beattie, J.3
Wilkie, M.J.4
Lightfoot, T.J.5
Coxhead, J.6
-
4
-
-
0031416750
-
Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis
-
Zingg JM, Jones PA. (1997) Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis. Carcinogenesis 18:869-882.
-
(1997)
Carcinogenesis
, vol.18
, pp. 869-882
-
-
Zingg, J.M.1
Jones, P.A.2
-
6
-
-
0035875049
-
Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies
-
Smiraglia DJ, Rush LJ, Fruhwald MC, Dai Z, Held WA, Costello JF et al. (2001) Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies. Hum Mol Genet 10:1413-1419. (Pubitemid 32640670)
-
(2001)
Human Molecular Genetics
, vol.10
, Issue.13
, pp. 1413-1419
-
-
Smiraglia, D.J.1
Rush, L.J.2
Fruhwald, M.C.3
Dai, Z.4
Held, W.A.5
Costello, J.F.6
Lang, J.C.7
Eng, C.8
Li, B.9
Wright, F.A.10
Caligiuri, M.A.11
Plass, C.12
-
8
-
-
66149100139
-
DNA methylation inhibits p53-mediated survivin repression
-
Nabilsi NH, Broaddus RR, Loose DS. (2009) DNA methylation inhibits p53-mediated survivin repression. Oncogene 28:2046-2050.
-
(2009)
Oncogene
, vol.28
, pp. 2046-2050
-
-
Nabilsi, N.H.1
Broaddus, R.R.2
Loose, D.S.3
-
9
-
-
0031442751
-
Increased DNA methyltransferase expression is associated with an early stage of human hepatocarcinogenesis
-
Sun L, Hui AM, Kanai Y, Sakamoto M, Hirohashi S. (1997) Increased DNA methyltransferase expression is associated with an early stage of human hepatocarcinogenesis. Jpn J Cancer Res 88:1165-1170. (Pubitemid 28048263)
-
(1997)
Japanese Journal of Cancer Research
, vol.88
, Issue.12
, pp. 1165-1170
-
-
Sun, L.1
Hui, A.-M.2
Kanai, Y.3
Sakamoto, M.4
Hirohashi, S.5
-
10
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R. (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69:915-926.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
11
-
-
55949083674
-
Age-related methylation in normal colon mucosa differs between the proximal and distal colon in patients who underwent colonoscopy
-
Horii J, Hiraoka S, Kato J, Harada K, Kuwaki K, Fujita H et al. (2008) Age-related methylation in normal colon mucosa differs between the proximal and distal colon in patients who underwent colonoscopy. Clin Biochem 41:1440-1448.
-
(2008)
Clin Biochem
, vol.41
, pp. 1440-1448
-
-
Horii, J.1
Hiraoka, S.2
Kato, J.3
Harada, K.4
Kuwaki, K.5
Fujita, H.6
-
12
-
-
0029919109
-
Hereditary cancer: Two hits revisited
-
Knudson AG. (1996) Hereditary cancer: two hits revisited. J Cancer Res Clin Oncol 122:135-140.
-
(1996)
J Cancer Res Clin Oncol
, vol.122
, pp. 135-140
-
-
Knudson, A.G.1
-
13
-
-
29244469466
-
The epigenetic progenitor origin of human cancer
-
DOI 10.1038/nrg1748
-
Feinberg AP, Ohlsson R, Henikoff S. (2006) The epigenetic progenitor origin of human cancer. Nat Rev Genet 7:21-33. (Pubitemid 41828945)
-
(2006)
Nature Reviews Genetics
, vol.7
, Issue.1
, pp. 21-33
-
-
Feinberg, A.P.1
Ohlsson, R.2
Henikoff, S.3
-
14
-
-
0031966161
-
A model for hepatocarcinogenesis treating phenotypical changes in focal hepatocellular lesions as epigenetic events
-
DOI 10.1016/S0025-5564(97)10007-4, PII S0025556497100074
-
Kopp-Schneider A, Portier C, Bannasch P. (1998) A model for hepatocarcinogenesis treating phenotypical changes in focal hepatocellular lesions as epigenetic events. Math Biosci 148:181-204. (Pubitemid 28224431)
-
(1998)
Mathematical Biosciences
, vol.148
, Issue.2
, pp. 181-204
-
-
Kopp-Schneider, A.1
Portier, C.2
Bannasch, P.3
-
15
-
-
34047190317
-
Epigenetic field for cancerization
-
Ushijima T. (2007) Epigenetic field for cancerization. J Biochem Mol Biol 40:142-150.
-
(2007)
J Biochem Mol Biol
, vol.40
, pp. 142-150
-
-
Ushijima, T.1
-
16
-
-
0033765496
-
Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis - A comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on eight CpG islands in microdissected specimens from patients with hepatocellular carcinoma
-
Kondo Y, Kanai Y, Sakamoto M, Mizokami M, Ueda R, Hirohashi S. (2000) Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis - a comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on eight CpG islands in microdissected specimens from patients with hepatocellular carcinoma. Hepatology 32:970-979.
-
(2000)
Hepatology
, vol.32
, pp. 970-979
-
-
Kondo, Y.1
Kanai, Y.2
Sakamoto, M.3
Mizokami, M.4
Ueda, R.5
Hirohashi, S.6
-
17
-
-
66149112853
-
Locating the stem cell niche and tracing hepatocyte lineages in human liver
-
Fellous TG, Islam S, Tadrous PJ, Elia G, Kocher HM, Bhattacharya S et al. (2009) Locating the stem cell niche and tracing hepatocyte lineages in human liver. Hepatology 49:1655-1663.
-
(2009)
Hepatology
, vol.49
, pp. 1655-1663
-
-
Fellous, T.G.1
Islam, S.2
Tadrous, P.J.3
Elia, G.4
Kocher, H.M.5
Bhattacharya, S.6
-
18
-
-
67349202729
-
New insights into liver stem cells
-
Gaudio E, Carpino G, Cardinale V, Franchitto A, Onori P, Alvaro D. (2009) New insights into liver stem cells. Dig Liver Dis 41:455-462.
-
(2009)
Dig Liver Dis
, vol.41
, pp. 455-462
-
-
Gaudio, E.1
Carpino, G.2
Cardinale, V.3
Franchitto, A.4
Onori, P.5
Alvaro, D.6
-
19
-
-
58449135983
-
Stem cells in liver regeneration, fibrosis and cancer: The good, the bad and the ugly
-
Alison MR, Islam S, Lim S. (2009) Stem cells in liver regeneration, fibrosis and cancer: the good, the bad and the ugly. J Pathol 217:282-298.
-
(2009)
J Pathol
, vol.217
, pp. 282-298
-
-
Alison, M.R.1
Islam, S.2
Lim, S.3
-
20
-
-
77951728697
-
Characterization of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver
-
Lorenzini S, Bird TG, Boulter L, Bellamy C, Samuel K, Aucott R et al. (2010) Characterization of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver. Gut 59:645-654.
-
(2010)
Gut
, vol.59
, pp. 645-654
-
-
Lorenzini, S.1
Bird, T.G.2
Boulter, L.3
Bellamy, C.4
Samuel, K.5
Aucott, R.6
-
21
-
-
60449087921
-
EpCAM positive hepatocellular carcinoma cells are tumor initiating cells with stem/progenitor cell features
-
Yamashita T, Ji J, Budhu A, Forgues M, Yang W, Wang HY et al. (2009) EpCAM positive hepatocellular carcinoma cells are tumor initiating cells with stem/progenitor cell features. Gastroenterology 136:1012-1024.
-
(2009)
Gastroenterology
, vol.136
, pp. 1012-1024
-
-
Yamashita, T.1
Ji, J.2
Budhu, A.3
Forgues, M.4
Yang, W.5
Wang, H.Y.6
-
22
-
-
77955852219
-
Epigenetic regulation of cancer stem cells in liver cancer: Current concepts and clinical implications
-
Marquardt JU, Factor VM, Thorgeirsson SS. (2010) Epigenetic regulation of cancer stem cells in liver cancer: current concepts and clinical implications. J Hepatol 53:568-577.
-
(2010)
J Hepatol
, vol.53
, pp. 568-577
-
-
Marquardt, J.U.1
Factor, V.M.2
Thorgeirsson, S.S.3
-
23
-
-
77954030910
-
Immunohistochemical staining of cancer stem cell markers in hepatocellular carcinoma
-
Lingala S, Cui YY, Chen X, Ruebner BH, Qian XF, Zern MA et al. (2010) Immunohistochemical staining of cancer stem cell markers in hepatocellular carcinoma. Exp Mol Pathol 89:27-35.
-
(2010)
Exp Mol Pathol
, vol.89
, pp. 27-35
-
-
Lingala, S.1
Cui, Y.Y.2
Chen, X.3
Ruebner, B.H.4
Qian, X.F.5
Zern, M.A.6
-
24
-
-
77957327502
-
Transgelin promotes migration and invasion of cancer stem cells
-
Lee EK, Han GY, Park HW, Song YJ, Kim CW. (2010) Transgelin promotes migration and invasion of cancer stem cells. J Proteome Res 9:5108-5117.
-
(2010)
J Proteome Res
, vol.9
, pp. 5108-5117
-
-
Lee, E.K.1
Han, G.Y.2
Park, H.W.3
Song, Y.J.4
Kim, C.W.5
-
25
-
-
0035870248
-
A gene hypermethylation profile of human cancer
-
Esteller M, Corn PG, Baylin SB, Herman JG. (2001) A gene hypermethylation profile of human cancer. Cancer Res 61:3225-3229. (Pubitemid 32695003)
-
(2001)
Cancer Research
, vol.61
, Issue.8
, pp. 3225-3229
-
-
Esteller, M.1
Corn, P.G.2
Baylin, S.B.3
Herman, J.G.4
-
26
-
-
0038339107
-
Age-related methylation of tumor suppressor and tumor-related genes: An analysis of autopsy samples
-
DOI 10.1038/sj.onc.1206651
-
Waki T, Tamura G, Sato M, Motoyama T. (2003) Age-related methylation of tumour suppressor and tumour-related genes: an analysis of autopsy samples. Oncogene 22:4128-4133. (Pubitemid 36819653)
-
(2003)
Oncogene
, vol.22
, Issue.26
, pp. 4128-4133
-
-
Waki, T.1
Tamura, G.2
Sato, M.3
Motoyama, T.4
-
27
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: From genes to environment
-
DOI 10.1038/nrc1934, PII NRC1934
-
Farazi PA, DePinho RA. (2006) Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 6:674-687. (Pubitemid 44286000)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.9
, pp. 674-687
-
-
Farazi, P.A.1
DePinho, R.A.2
-
28
-
-
27744483159
-
Effect of promoter methylation of the p16 gene on phosphorylation of retinoblastoma gene product and growth of hepatocellular carcinoma cells
-
DOI 10.1159/000089288
-
Maeta Y, Shiota G, Okano J, Murawaki Y. (2005) Effect of promoter methylation of the p16 gene on phosphorylation of retinoblastoma gene product and growth of hepatocellular carcinoma cells. Tumour Biol 26:300-305. (Pubitemid 41619460)
-
(2005)
Tumor Biology
, vol.26
, Issue.6
, pp. 300-305
-
-
Maeta, Y.1
Shiota, G.2
Okano, J.-I.3
Murawaki, Y.4
-
29
-
-
0141648473
-
Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis
-
Lee S, Lee HJ, Kim JH, Lee HS, Jang JJ, Kang GH. (2003) Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis. Am J Pathol 163:1371-1378. (Pubitemid 37175085)
-
(2003)
American Journal of Pathology
, vol.163
, Issue.4
, pp. 1371-1378
-
-
Lee, S.1
Lee, H.J.2
Kim, J.-H.3
Lee, H.-S.4
Jang, J.J.5
Kang, G.H.6
-
30
-
-
0035056507
-
INK4A gene promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus
-
DOI 10.1136/gut.48.3.372
-
Kaneto H, Sasaki S, Yamamoto H, Itoh F, Toyota M, Suzuki H et al. (2001) Detection of hypermethylation of the p16(INK4A) gene promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus. Gut 48:372-377. (Pubitemid 32269566)
-
(2001)
Gut
, vol.48
, Issue.3
, pp. 372-377
-
-
Kaneto, H.1
Sasaki, S.2
Yamamoto, H.3
Itoh, F.4
Toyota, M.5
Suzuki, H.6
Ozeki, I.7
Iwata, N.8
Ohmura, T.9
Satoh, T.10
Karino, Y.11
Satoh, T.12
Toyota, J.13
Satoh, M.14
Endo, T.15
Omata, M.16
Imai, K.17
-
31
-
-
0037455979
-
P16 Hypermethylation in the early stage of hepatitis B virus-associated hepatocarcinogenesis
-
DOI 10.1016/S0304-3835(02)00613-4
-
Shim YH, Yoon GS, Choi HJ, Chung YH, Yu E. (2003) p16 Hypermethylation in the early stage of hepatitis B virus-associated hepatocarcinogenesis. Cancer Lett 190:213-219. (Pubitemid 36136020)
-
(2003)
Cancer Letters
, vol.190
, Issue.2
, pp. 213-219
-
-
Shim, Y.-H.1
Yoon, G.-S.2
Choi, H.-J.3
Chung, Y.H.4
Yu, E.5
-
32
-
-
40949161396
-
Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma
-
DOI 10.1002/hep.22110
-
Nishida N, Nagasaka T, Nishimura T, Ikai I, Boland CR, Goel A. (2008) Aberrant methylation of multiple tumour suppressor genes in ageing liver, chronic hepatitis, and hepatocellular carcinoma. Hepatology 47: 908-918. (Pubitemid 351449682)
-
(2008)
Hepatology
, vol.47
, Issue.3
, pp. 908-918
-
-
Nishida, N.1
Nagasaka, T.2
Nishimura, T.3
Ikai, I.4
Boland, C.R.5
Goel, A.6
-
33
-
-
0032924622
-
P16(INK4) is inactivated by extensive CpG methylation in human hepatocellular carcinoma
-
DOI 10.1016/S0016-5085(99)70137-X
-
Matsuda Y, Ichida T, Matsuzawa J, Sugimura K, Asakura H. (1999) p16(INK4A) is inactivated by extensive CpG methylation in human hepatocellular carcinoma. Gastroenterology 116:394-400. (Pubitemid 29055363)
-
(1999)
Gastroenterology
, vol.116
, Issue.2
, pp. 394-400
-
-
Matsuda, Y.1
Ichida, T.2
Matsuzawa, J.3
Sugimura, K.4
Asakura, H.5
-
34
-
-
0030920634
-
The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas
-
DOI 10.1002/(SICI)1097-0215(19970502)71:3<355::AID-IJC8>3.0.CO;2-X
-
Kanai Y, Ushijima S, Hui AM, Ochiai A, Tsuda H, Sakamoto M et al. (1997) The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas. Int J Cancer 71:355-359. (Pubitemid 27224296)
-
(1997)
International Journal of Cancer
, vol.71
, Issue.3
, pp. 355-359
-
-
Kanai, Y.1
Ushijima, S.2
Hui, A.-M.3
Ochiai, A.4
Tsuda, H.5
Sakamoto, M.6
Hirohashi, S.7
-
35
-
-
0033818628
-
Frequent p15 promoter methylation in tumour and peripheral blood from hepatocellular carcinoma patients
-
Wong IH, Lo YM, Yeo W, Lau WY, Johnson PJ. (2000) Frequent p15 promoter methylation in tumour and peripheral blood from hepatocellular carcinoma patients. Clin Cancer Res 6:3516-3521.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3516-3521
-
-
Wong, I.H.1
Lo, Y.M.2
Yeo, W.3
Lau, W.Y.4
Johnson, P.J.5
-
36
-
-
0035042611
-
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity
-
DOI 10.1038/88225
-
Yoshikawa H, Matsubara K, Qian GS, Jackson P, Groopman JD, Manning JE et al. (2001) SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity. Nat Genet 28:29-35. (Pubitemid 32405812)
-
(2001)
Nature Genetics
, vol.28
, Issue.1
, pp. 29-35
-
-
Yoshikawa, H.1
Matsubara, K.2
Qian, G.-S.3
Jackson, P.4
Groopman, J.D.5
Manning, J.E.6
Harris, C.C.7
Herman, J.G.8
-
37
-
-
0035890771
-
Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily
-
Du Y, Carling T, Fang W, Piao Z, Sheu JC, Huang S. (2001) Hypermethylation in human cancers of the RIZ1 tumour suppressor gene, a member of a histone/protein methyltransferase superfamily. Cancer Res 61:8094-8099. (Pubitemid 33091596)
-
(2001)
Cancer Research
, vol.61
, Issue.22
, pp. 8094-8099
-
-
Du, Y.1
Carling, T.2
Fang, W.3
Piao, Z.4
Sheu, J.-C.5
Huang, S.6
-
38
-
-
77949877704
-
High-throughput assessment of CpG site methylation for distinguishing between HCV-cirrhosis and HCV-associated hepatocellular carcinoma
-
Archer KJ, Mas VR, Maluf DG, Fisher RA. (2010) High-throughput assessment of CpG site methylation for distinguishing between HCV-cirrhosis and HCV-associated hepatocellular carcinoma. Mol Genet Genomics 283:341-349.
-
(2010)
Mol Genet Genomics
, vol.283
, pp. 341-349
-
-
Archer, K.J.1
Mas, V.R.2
Maluf, D.G.3
Fisher, R.A.4
-
39
-
-
41049096579
-
APC promoter methylation and protein expression in hepatocellular carcinoma
-
Csepregi A, Rocken C, Hoffmann J, Gu P, Saliger S, Muller O et al. (2008) APC promoter methylation and protein expression in hepatocellular carcinoma. J Cancer Res Clin Oncol 134:579-589.
-
(2008)
J Cancer Res Clin Oncol
, vol.134
, pp. 579-589
-
-
Csepregi, A.1
Rocken, C.2
Hoffmann, J.3
Gu, P.4
Saliger, S.5
Muller, O.6
-
40
-
-
39749198581
-
Epigenetic Inhibition of Nuclear Receptor Small Heterodimer Partner Is Associated with and Regulates Hepatocellular Carcinoma Growth
-
DOI 10.1053/j.gastro.2008.01.006, PII S0016508508000334
-
He N, Park K, Zhang Y, Huang J, Lu S, Wang L. (2008) Epigenetic inhibition of nuclear receptor small heterodimer partner is associated with and regulates hepatocellular carcinoma growth. Gastroenterology 134:793-802. (Pubitemid 351312736)
-
(2008)
Gastroenterology
, vol.134
, Issue.3
, pp. 793-802
-
-
He, N.1
Park, K.2
Zhang, Y.3
Huang, J.4
Lu, S.5
Wang, L.6
-
41
-
-
77954663598
-
DNA methylation of ESR-1 and N-33 in colorectal mucosa of patients with ulcerative colitis (UC)
-
Arasaradnam RP, Khoo KT, Bradburn M, Mathers JC, Kelly SB. (2010) DNA methylation of ESR-1 and N-33 in colorectal mucosa of patients with ulcerative colitis (UC). Epigenetics 5:422-426.
-
(2010)
Epigenetics
, vol.5
, pp. 422-426
-
-
Arasaradnam, R.P.1
Khoo, K.T.2
Bradburn, M.3
Mathers, J.C.4
Kelly, S.B.5
-
42
-
-
66249114998
-
A multicentre, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's oesophagus
-
Jin Z, Cheng Y, Gu W, Zheng Y, Sato F, Mori Y et al. (2009) A multicentre, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's oesophagus. Cancer Res 69:4112-4115.
-
(2009)
Cancer Res
, vol.69
, pp. 4112-4115
-
-
Jin, Z.1
Cheng, Y.2
Gu, W.3
Zheng, Y.4
Sato, F.5
Mori, Y.6
-
43
-
-
36949027736
-
Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's esophagus
-
DOI 10.1111/j.1349-7006.2007.00663.x
-
Clement G, Guilleret I, He B, Yagui-Beltran A, Lin YC, You L et al. (2008) Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's oesophagus. Cancer Sci 99:46-53. (Pubitemid 350239030)
-
(2008)
Cancer Science
, vol.99
, Issue.1
, pp. 46-53
-
-
Clement, G.1
Guilleret, I.2
He, B.3
Yagui-Beltran, A.4
Lin, Y.-C.5
You, L.6
Xu, Z.7
Shi, Y.8
Okamoto, J.9
Benhattar, J.10
Jablons, D.11
-
44
-
-
35148873511
-
Cigarette smoke induces demethylation of prometastatic oncogene synuclein-gamma in lung cancer cells by downregulation of DNMT3B
-
Liu H, Zhou Y, Boggs SE, Belinsky SA, Liu J. (2007) Cigarette smoke induces demethylation of prometastatic oncogene synuclein-gamma in lung cancer cells by downregulation of DNMT3B. Oncogene 26:5900-5910.
-
(2007)
Oncogene
, vol.26
, pp. 5900-5910
-
-
Liu, H.1
Zhou, Y.2
Boggs, S.E.3
Belinsky, S.A.4
Liu, J.5
-
45
-
-
68949217876
-
Potential of DNMT and its epigenetic regulation for lung cancer therapy
-
Tang M, Xu W, Wang Q, Xiao W, Xu R. (2009) Potential of DNMT and its epigenetic regulation for lung cancer therapy. Curr Genomics 10:336-352.
-
(2009)
Curr Genomics
, vol.10
, pp. 336-352
-
-
Tang, M.1
Xu, W.2
Wang, Q.3
Xiao, W.4
Xu, R.5
-
46
-
-
74749090903
-
Correlation of CpG island methylator phenotype with poor prognosis in hepatocellular carcinoma
-
Cheng Y, Zhang C, Zhao J, Wang C, Xu Y, Han Z et al. (2010) Correlation of CpG island methylator phenotype with poor prognosis in hepatocellular carcinoma. Exp Mol Pathol 88:112-117.
-
(2010)
Exp Mol Pathol
, vol.88
, pp. 112-117
-
-
Cheng, Y.1
Zhang, C.2
Zhao, J.3
Wang, C.4
Xu, Y.5
Han, Z.6
-
47
-
-
77950299830
-
Immunoprecipitation of nucleosomal DNA is a novel procedure to improve the sensitivity of serum screening for the p16 hypermethylation associated with colon cancer
-
Sakamoto J, Fujiya M, Okamoto K, Nata T, Inaba Y, Moriichi K et al. (2010) Immunoprecipitation of nucleosomal DNA is a novel procedure to improve the sensitivity of serum screening for the p16 hypermethylation associated with colon cancer. Cancer Epidemiol 34:194-199.
-
(2010)
Cancer Epidemiol
, vol.34
, pp. 194-199
-
-
Sakamoto, J.1
Fujiya, M.2
Okamoto, K.3
Nata, T.4
Inaba, Y.5
Moriichi, K.6
-
48
-
-
66349102768
-
Methylation of TFPI2 in stool DNA: A potential novel biomarker for the detection of colorectal cancer
-
Glockner SC, Dhir M, Yi JM, McGarvey KE, Van Neste L, Louwagie J et al. (2009) Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer. Cancer Res 69:4691-4699.
-
(2009)
Cancer Res
, vol.69
, pp. 4691-4699
-
-
Glockner, S.C.1
Dhir, M.2
Yi, J.M.3
McGarvey, K.E.4
Van Neste, L.5
Louwagie, J.6
-
49
-
-
0037068353
-
DNA methylation in cancer: Too much, but also too little
-
Ehrlich M. (2002) DNA methylation in cancer: too much, but also too little. Oncogene 21:5400-5413.
-
(2002)
Oncogene
, vol.21
, pp. 5400-5413
-
-
Ehrlich, M.1
-
50
-
-
58149330690
-
Methylation of Tip30 promoter is associated with poor prognosis in human hepatocellular carcinoma
-
Lu B, Ma Y, Wu G, Tong X, Guo H, Liang A et al. (2008) Methylation of Tip30 promoter is associated with poor prognosis in human hepatocellular carcinoma. Clin Cancer Res 14:7405-7412.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7405-7412
-
-
Lu, B.1
Ma, Y.2
Wu, G.3
Tong, X.4
Guo, H.5
Liang, A.6
-
51
-
-
0035158704
-
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
-
DOI 10.1038/83730
-
Jackson-Grusby L, Beard C, Possemato R, Tudor M, Fambrough D, Csankovszki G et al. (2001) Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat Genet 27:31-39. (Pubitemid 32044515)
-
(2001)
Nature Genetics
, vol.27
, Issue.1
, pp. 31-39
-
-
Jackson-Grusby, L.1
Beard, C.2
Possemato, R.3
Tudor, M.4
Fambrough, D.5
Csankovszki, G.6
Dausman, J.7
Lee, P.8
Wilson, C.9
Lander, E.10
Jaenisch, R.11
-
52
-
-
33745922882
-
TIP30 inhibits growth of HCC cell lines and inhibits HCC xenografts in mice in combination with 5-FU
-
DOI 10.1002/hep.21213
-
Zhao J, Zhang X, Shi M, Xu H, Jin J, Ni H et al. (2006) TIP30 inhibits growth of HCC cell lines and inhibits HCC xenografts in mice in combination with 5-FU. Hepatology 44:205-215. (Pubitemid 44049153)
-
(2006)
Hepatology
, vol.44
, Issue.1
, pp. 205-215
-
-
Zhao, J.1
Zhang, X.2
Shi, M.3
Xu, H.4
Jin, J.5
Ni, H.6
Yang, S.7
Dai, J.8
Wu, M.9
Guo, Y.10
-
53
-
-
34548304069
-
Activation of p53 by MEG3 non-coding RNA
-
DOI 10.1074/jbc.M702029200
-
Zhou Y, Zhong Y, Wang Y, Zhang X, Batista DL, Gejman R et al. (2007) Activation of p53 byMEG3 non-coding RNA. J Biol Chem 282:24731-24742. (Pubitemid 47347547)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.34
, pp. 24731-24742
-
-
Zhou, Y.1
Zhong, Y.2
Wang, Y.3
Zhang, X.4
Batista, D.L.5
Gejman, R.6
Ansell, P.J.7
Zhao, J.8
Weng, C.9
Klibanski, A.10
-
54
-
-
0033737604
-
Correlations of partial and extensive methylation at the p14(ARF) locus with reduced mRNA expression in colorectal cancer cell lines and clinicopathological features in primary tumours
-
Zheng S, Chen P, McMillan A, Lafuente A, Lafuente MJ, Ballesta A et al. (2000) Correlations of partial and extensive methylation at the p14(ARF) locus with reduced mRNA expression in colorectal cancer cell lines and clinicopathological features in primary tumours. Carcinogenesis 21:2057-2064.
-
(2000)
Carcinogenesis
, vol.21
, pp. 2057-2064
-
-
Zheng, S.1
Chen, P.2
McMillan, A.3
Lafuente, A.4
Lafuente, M.J.5
Ballesta, A.6
-
55
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1in human cancers
-
Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC et al. (1995) 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1in human cancers. Nat Med 1:686-692.
-
(1995)
Nat Med
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
-
56
-
-
77957361278
-
Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors
-
Hernandez-Vargas H, Lambert MP, Le Calvez-Kelm F, Gouysse G, McKay-Chopin S, Tavtigian SV et al. (2010) Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors. PLoS ONE 5:e9749.
-
(2010)
PLoS ONE
, vol.5
-
-
Hernandez-Vargas, H.1
Lambert, M.P.2
Le Calvez-Kelm, F.3
Gouysse, G.4
McKay-Chopin, S.5
Tavtigian, S.V.6
-
57
-
-
77149160616
-
Race, ethnicity, and socioeconomic status influence the survival of patients with hepatocellular carcinoma in the United States
-
Artinyan A, Mailey B, Sanchez-Luege N, Khalili J, Sun CL, Bhatia S et al. (2010) Race, ethnicity, and socioeconomic status influence the survival of patients with hepatocellular carcinoma in the United States. Cancer 116:1367-1377.
-
(2010)
Cancer
, vol.116
, pp. 1367-1377
-
-
Artinyan, A.1
Mailey, B.2
Sanchez-Luege, N.3
Khalili, J.4
Sun, C.L.5
Bhatia, S.6
-
58
-
-
68749097208
-
MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer
-
Ng EK, Tsang WP, Ng SS, Jin HC, Yu J, Li JJ et al. (2009) MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. Br J Cancer 101:699-706.
-
(2009)
Br J Cancer
, vol.101
, pp. 699-706
-
-
Ng, E.K.1
Tsang, W.P.2
Ng, S.S.3
Jin, H.C.4
Yu, J.5
Li, J.J.6
-
59
-
-
0037598752
-
Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas
-
DOI 10.1002/ijc.11127
-
Saito Y, Kanai Y, Nakagawa T, Sakamoto M, Saito H, Ishii H et al. (2003) Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas. Int J Cancer 105:527-532. (Pubitemid 36578558)
-
(2003)
International Journal of Cancer
, vol.105
, Issue.4
, pp. 527-532
-
-
Saito, Y.1
Kanai, Y.2
Nakagawa, T.3
Sakamoto, M.4
Saito, H.5
Ishi, H.6
Hirohashi, S.7
-
60
-
-
28844480321
-
Management of hepatocellular carcinoma
-
DOI 10.1002/hep.20933
-
Bruix J, Sherman M. (2005) Management of hepatocellular carcinoma. Hepatology 42:1208-1236. (Pubitemid 43112690)
-
(2005)
Hepatology
, vol.42
, Issue.5
, pp. 1208-1236
-
-
Bruix, J.1
Sherman, M.2
-
61
-
-
77955973284
-
Advanced hepatocellular carcinoma: Which staging systems best predict prognosis?
-
Huitzil-Melendez FD, Capanu M, O'Reilly EM, Duffy A, Gansukh B, Saltz LL et al. (2010) Advanced hepatocellular carcinoma: which staging systems best predict prognosis? J Clin Oncol 28:2889-2895.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2889-2895
-
-
Huitzil-Melendez, F.D.1
Capanu, M.2
O'Reilly, E.M.3
Duffy, A.4
Gansukh, B.5
Saltz, L.L.6
-
62
-
-
57349090407
-
Gene expression in fixed tissues and outcome in hepatocellular carcinoma
-
Hoshida Y, Villanueva A, Kobayashi M, Peix J, Chiang DY, Camargo A et al. (2008) Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N Engl J Med 359:1995-2004.
-
(2008)
N Engl J Med
, vol.359
, pp. 1995-2004
-
-
Hoshida, Y.1
Villanueva, A.2
Kobayashi, M.3
Peix, J.4
Chiang, D.Y.5
Camargo, A.6
-
63
-
-
48549101423
-
CpG island methylator phenotype (CIMP) in cancer: Causes and implications
-
Teodoridis JM, Hardie C, Brown R. (2008) CpG island methylator phenotype (CIMP) in cancer: causes and implications. Cancer Lett 268: 177-186.
-
(2008)
Cancer Lett
, vol.268
, pp. 177-186
-
-
Teodoridis, J.M.1
Hardie, C.2
Brown, R.3
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