Advanced hepatocellular carcinoma: Which staging systems best predict prognosis?

Journal of Clinical Oncology

Volumn 28, Issue 17, 2010, Pages 2889-2895

  Huitzil Melendez, Fidel David ^a   Capanu, Marinela ^a   O'Reilly, Eileen M ^a   Duffy, Austin ^a   Gansukh, Bolorsukh ^a   Saltz, Leonard L ^a   Abou Alfa, Ghassan K ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABDOMINAL PAIN; ADULT; ADVANCED CANCER; AGED; ARTICLE; BARCELONA CLINIC LIVER CANCER; CANCER OF THE LIVER ITALIAN PROGRAM; CANCER STAGING; CANCER SURVIVAL; CHINESE UNIVERSITY PROGNOSTIC INDEX; CONCORDANCE INDEX; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; ESOPHAGUS VARICES; FEMALE; GROUPE D ETUDE ET DE TRAITEMENT DU CARCINOME HEPATOCELLULAIRE; HUMAN; INTERMETHOD COMPARISON; JAPAN INTEGRATED STAGING; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RATING SCALE; LIVER TUMOR; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATHOLOGY; RETROSPECTIVE STUDY; SURVIVAL; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 77955973284     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2009.25.9895     Document Type: Article

References (27)

1. Abou-Alfa GK: Hepatocellular carcinoma: Molecular biology and therapy. Semin Oncol 33:S79-S83, 2006 (suppl 11)
2. Abou-Alfa GK: Selection of patients with hepatocellular carcinoma for sorafenib. J Natl Compr Canc Netw 7:397-403, 2009
3. Lei HJ, Chau GY, Lui WY, et al: Prognostic value and clinical relevance of the 6th Edition 2002 American Joint Committee on Cancer staging system in patients with resectable hepatocellular carcinoma. J Am Coll Surg 203:426-435, 2006
4. Okuda K, Ohtsuki T, Obata H, et al: Natural history of hepatocellular carcinoma and prognosis in relation to treatment: Study of 850 patients. Cancer 56: 918-928, 1985 (Pubitemid 15228292)
5. Llovet JM, Brú C, Bruix J: Prognosis of hepatocellular carcinoma: The BCLC staging classification. Sem Liv Dis 19:329-338, 1999
6. A new prognostic system for hepatocellular carcinoma: A retrospective study of 435 patients - The Cancer of the Liver Italian Program (CLIP) investigators. Hepatology 28:751-755, 1998
7. Prospective validation of the CLIP score: A new prognostic system for patients with cirrhosis and hepatocellular carcinoma - The Cancer of the Liver Italian Program (CLIP) Investigators. Hepatology 31:840-845, 2000
8. Leung TW, Tang AM, Zee B, et al: Construction of the Chinese University Prognostic Index for hepatocellular carcinoma and comparison with the TNM staging system, the Okuda staging system, and the Cancer of the Liver Italian Program staging system: A study based on 926 patients. Cancer 94:1760-1769, 2002 (Pubitemid 34241115)
9. Kudo M, Chung H, Osaki Y: Prognostic staging system for hepatocellular carcinoma (CLIP score): Its value and limitations, and a proposal for a new staging system, the Japan Integrated Staging Score (JIS score). J Gastroenterol 38:207-215, 2003 (Pubitemid 36527122)
10. Kudo M, Chung H, Haji S, et al: Validation of a new prognostic staging system for hepatocellular carcinoma: The JIS score compared with the CLIP score. Hepatology 40:1396-1405, 2004 (Pubitemid 39657014)
11. Chevret S, Trinchet JC, Mathieu D, et al: A new prognostic classification for predicting survival in patients with hepatocellular carcinoma: Groupe d'Etude et de Traitement du Carcinome Hépatocellulaire. J Hepatol 31:133-141, 1999 (Pubitemid 29287619)
12. Bruix J, Sherman M, Llovet JM, et al: Clinical management of hepatocellular carcinoma: Conclusions of the Barcelona-2000 EASL conference - European Association for the Study of the Liver. J Hepatol 35:421-430, 2001 (Pubitemid 32844200)
13. Cha C, Fong Y, Jarnagin WR, et al: Predictors and patterns of recurrence after resection of hepatocellular carcinoma. J Am Coll Surg 197:753-758, 2003 (Pubitemid 38199576)
14. Covey AM, Maluccio MA, Schubert J, et al: Particle embolization of recurrent hepatocellular carcinoma after hepatectomy. Cancer 106:2181-2189, 2006 (Pubitemid 43673240)
15. Buccheri G, Ferrigno D, Tamburini M: Karnofsky and ECOG performance status scoring in lung cancer: A prospective, longitudinal study of 536 patients from a single institution. Eur J Cancer 32A:1135-1141, 1996
16. Riffenburgh RH: Statistics in Medicine (ed 2). Burlington, MA, Elsevier Academic Press, 2006, pp. xli, 622
17. Llovet JM, Di Bisceglie AM, Bruix J, et al: Design and endpoints of clinical trials in hepatocellular carcinoma. J Natl Cancer Inst 100:698-711, 2008
18. Marrero JA, Fontana RJ, Barrat A, et al: Prognosis of hepatocellular carcinoma: Comparison of 7 staging systems in an American cohort. Hepatology 41:707-716, 2005 (Pubitemid 40462931)
19. Cillo U, Vitale A, Grigoletto F, et al: Prospective validation of the Barcelona Clinic Liver Cancer staging system. J Hepatol 44:723-731, 2006
20. Llovet JM: Statement at the State of the Clinical Science Meeting: Hepatocellular Carcinoma (HCC). Presented at the State of Clinical Science Meeting, Bethesda, MD, December 12-13, 2008
21. Giannini E, Botta F, Fasoli A, et al: Progressive liver functional impairment is associated with an increase in AST/ALT ratio. Dig Dis Sci 44:1249-1253, 1999 (Pubitemid 29297237)
22. Giannini E, Risso D, Botta F, et al: Validity and clinical utility of the aspartate aminotransferasealanine aminotransferase ratio in assessing disease severity and prognosis in patients with hepatitis C virus-related chronic liver disease. Arch Intern Med 163:218-224, 2003 (Pubitemid 36120190)
23. Collette S, Bonnetain F, Paoletti X, et al: Prognosis of advanced hepatocellular carcinoma: Comparison of three staging systems in two French clinical trials. Ann Oncol 19:1117-1126, 2008 (Pubitemid 351796337)
24. Guglielmi A, Ruzzenente A, Pachera S, et al: Comparison of seven staging systems in cirrhotic patients with hepatocellular carcinoma in a cohort of patients who underwent radiofrequency ablation with complete response. Am J Gastroenterol 103: 597-604, 2008 (Pubitemid 351405970)
25. Kondo K, Chijiiwa K, Nagano M, et al: Comparison of seven prognostic staging systems in patients who undergo hepatectomy for hepatocellular carcinoma. Hepatogastroenterology 54:1534-1538, 2007 (Pubitemid 47203464)
26. Grieco A, Pompili M, Caminiti G, et al: Prognostic factors for survival in patients with early-intermediate hepatocellular carcinoma undergoing non-surgical therapy: Comparison of Okuda, CLIP, and BCLC staging systems in a single Italian centre. Gut 54:411-418, 2005 (Pubitemid 40299100)
27. Cillo U, Bassanello M, Vitale A, et al: The critical issue of hepatocellular carcinoma prognostic classification: Which is the best tool available? J Hepatol 40:124-131, 2004 (Pubitemid 38064721)