Cationic liposomes as gene delivery system: Transfection efficiency and new application

Pharmazie

Volumn 66, Issue 3, 2011, Pages 158-164

  Xiong, F ^a   Mi, Z ^b   Gu, Ning ^a  

^a Southeast University   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; 2,3 DIOLEYLOXY N [2 (SPERMINECARBOXAMIDO)ETHYL] N,N DIMETHYL 1 PROPANIMINIUMPENTA HYDROCHLORIDE; BCG VACCINE; CATIONIC LIPOSOME; CHOLESTEROL; DIOLEOYL ALPHA PHOSPHATIDYLETHANOLAMINE; DIOLEOYL PHOSPHATIDYL CHOLIN; DNA VACCINE; DOXORUBICIN; GANCICLOVIR; HUMAN SERUM ALBUMIN; LIPOPLEX; LIPOSOME; N (2 HYDROXYETHYL) N,N DIMETHYL 2,3 BIS(TETRADECYLOXY) 1 PROPANAMINIUM; N',N' DIOCTADECYL N 4,8 DIAZA 10 AMINODECANOYLGLYCINE AMIDE; PHOSPHOLIPID DERIVATIVE; THYMIDINE KINASE; UNCLASSIFIED DRUG; VINBLASTINE; CATION; DNA; DRUG CARRIER; LIPID; MACROGOL DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; BREAST ADENOCARCINOMA; CELL INTERACTION; GENE DELIVERY SYSTEM; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; HETEROZYGOTE; HUMAN; JAPANESE ENCEPHALITIS; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; REVIEW; SINGLE DRUG DOSE; TRANSFECTION EFFICIENCY; CELL CULTURE; CHEMISTRY; CONFORMATION; METHODOLOGY;

CATIONS; CELLS, CULTURED; DNA; DRUG CARRIERS; GENE TRANSFER TECHNIQUES; HUMANS; LIPIDS; LIPOSOMES; MOLECULAR CONFORMATION; PARTICLE SIZE; POLYETHYLENE GLYCOLS; TRANSFECTION;

EID: 79957521275     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2011.0768     Document Type: Review

References (71)

1. Abu Lila AS, Kizuki S, Doi Y, Suzuki T, Ishida T, Kiwada H (2009) Oxaliplatin encapsulated in PEG-coated cationic liposomes induces significant tumor growth suppression via a dual-targeting approach in a murine solid tumor model. J Control Release 137: 8-14.
2. Anchordoquy TJ, Carpenter JF, Kroll DJ (1997) Maintenance of transfection rates and physical characterization of lipid/DNA complexes after freeze-drying and rehydration. Arch Biochem Biophys 348: 199-206. (Pubitemid 27514688)
3. Barron LG, Uyechi LS, Szoka FC (1999) Cationic lipids are essential for gene delivery mediated by intravenous administration of lipoplexes. Gene Ther 6: 1179-1183. (Pubitemid 29295226)
4. Bhowmick S, Mazumdar T, Sinha R, Ali N (2010) Comparison of liposome based antigen delivery systems for protection against Leishmania donovani. J Control Release 141: 199-207.
5. Birchall JC, Kellaway IW, Mills SN (1999) Physico-chemical characterisation and transfection efficiency of lipid-based gene delivery complexes. Int J Pharm 183: 195-207. (Pubitemid 29257965)
6. Boffa LC, Menichini P, Bolognesi C, Cutrona G, Roncella S, Damonte GL, Millo E, Mariani MR, Matis S, Russo D, Ciliutti P, Ferrarin M (2007) Lack of mutagenicity and clastogenicity of PNAEμ-NLS targeted to a regulatory sequence of the translocated c-myc oncogene in Burkitt's lymphoma. Mutat Res 628: 129-137. (Pubitemid 46330882)
7. Brgles M, Habjanec L, Halassy B, Tomasić J (2009) Liposome fusogenicity and entrapment efficiency of antigen determine the Th1/Th2 bias of antigen-specific immune response. Vaccine 27: 5435-5442.
8. Buyens K, Lucas B, Raemdonck K, Braeckmans K, Vercammen J, Hendrix J, Engelborghs Y, De Smedt SC, Sanders NN (2008) A fast and sensitive method for measuring the integrity of siRNA-carrier complexes in full human serum. J Control Release 126: 67-76.
9. Cardoso AL, Simões S, de Almeida LP, Plesnila N, Pedroso de Lima MC, Wagner E, Culmsee C (2008) Tf-lipoplexes for neuronal siRNA delivery: A promising system to mediate gene silencing in the CNS. J Control Release 132: 113-123.
10. Cheng JY, Huang HN, Tseng WC, Li TL, Chan YL, Cheng KC, Wu CJ (2009) Transcutaneous immunization by lipoplex-patch based DNA vaccines is effective vaccination against Japanese encephalitis virus infection. J Control Release 135: 242-249.
11. de la Torre LG, Rosada RS, Trombone AP, Frantz FG, Coelho-Castelo AA, Silva CL, Santana MH (2009) The synergy between structural stability and DNA-binding controls the antibody production in EPC/DOTAP/DOPE liposomes and DOTAP/DOPE lipoplexes. Colloids Surf B Biointerfaces 73: 175-184.
12. De Rosa G, De Stefano D, Laguardia V, Arpicco S, Simeon V, Carnuccio R, Fattal E (2008) Novel cationic liposome formulation for the delivery of an oligonucleotide decoy to NF-κB into activated macrophages. Eur J Pharm Biopharm 70: 7-18.
13. Deshpande MC, Davies MC, Garnett MC, Williams PM, Armitage D, Bailey L, Vamvakaki M, Armes SP, Stolnik S (2004) The effect of poly(ethylene glycol) molecular architecture on cellular interaction and uptake of DNA complexes. J Control Release 97: 143-156. (Pubitemid 38624517)
14. Dimitriadis GJ (1978) Translation of rabbit globin mRNA introduced by liposomes into mouse lymphocytes. Nature 274: 923-924.
15. Ding W, Hattori Y, Higashiyama K, Maitani Y (2008) Hydroxyethylated cationic cholesterol derivatives in liposome vectors promote gene expression in the lung. Int J Pharm 354: 196-203.
16. Düzgüne N, Nir S (1999) Mechanisms and kinetics of liposome-cell interactions. Adv Drug Deliv Rev 40: 3-18.
17. Esposito C, Generosi J, Mossa G, Masotti A, Castellano AC (2006) The analysis of serum effects on structure, size and toxicity of DDAB-DOPE and DC-Chol-DOPE lipoplexes contributes to explain their different transfection efficiency. Colloids Surf B Biointerfaces 53: 187-192. (Pubitemid 44791895)
18. Faneca H, Faustino A, Pedroso de Lima MC (2008) Synergistic antitumoral effect of vinblastine and HSV-Tk/GCV gene therapy mediated by albumin-associated cationic liposomes. J Control Release 126: 175-184.
19. Farhood H, Serbina N, Huang L (1995) The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acta 1235: 289-295.
20. Felgner PL, Gadek TR, Holm M, Roman R, Chan HW, Wenz M, Northrop JP, Ringold GM, Danielsen M (1987) Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci 84: 7413-7417.
21. Ferrari ME, Nguyen CM, Zelphati O, Tsai Y, Felgner PL (1998) Analytical methods for the characterization of cationic lipid-nucleic acid complexes. Hum Gene Ther 9: 341-351. (Pubitemid 28085022)
22. Flasterstein OE, Samira S, Rochlin E, Balasingam S, Mann AJ, Lambkin-Williams R, Spira J, Goldwaser I, Ellis R, Barenholz Y (2010) Immunogenicity, protective efficacy and mechanism of novel CCS adjuvanted influenza vaccine. Vaccine 28: 6527-6541.
23. Gao X, Huang L (1995) Cationic liposome-mediated gene transfer. Gene Ther 2: 710-722. (Pubitemid 26043284)
24. Gonçalves E, Debs RJ, Heath TD (2004) The effect of liposome size on the final lipid/DNA ratio of cationic lipoplexes. Biophys J 86: 1554-1563. (Pubitemid 38295590)
25. Han M, Chen JL, Hu Y, He CL, Shuai WP, Yu JH, Chen HL, Liang WQ, Mayumi T, Shinsaku N, Gao JQ (2008) In vitro and in vivo tumor suppressive activity induced by human telomerase transcriptase-targeting antisense oligonucleotides mediated by cationic liposomes. J Biosci Bioeng 106: 243-247.
26. Henriksen-Lacey M, Christensen D, Bramwell VW, Lindenstrøm T, Agger EM, Andersen P, Perrie Y (2010) Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce a CMI response. J Control Release 145: 102-108.
27. Jääskeläinen I, Peltola S, Honkakoski P, Mönkkönen J, Urtti A (2000) A lipid carrier with a membrane active component and a small complex size are required for efficient cellular delivery of anti-sense phosphorothioate oligonucleotides. Eur J Pharm Sci 10: 187-193. (Pubitemid 30190094)
28. Kang SW, Lim HW, Seo SW, Jeon O, Lee M, Kim BS (2008) Nanosphere-mediated delivery of vascular endothelial growth factor gene for therapeutic angiogenesis in mouse ischemic limbs. Biomaterials 29: 1109-1117. (Pubitemid 350296314)
29. Kerner M, Meyuhas O, Hirsch-Lerner D, Rosen LJ, Min Z, Barenholz Y (2001) Interplay in lipoplexes between type of pDNA promoter and lipid composition determines transfection efficiency of human growth hormone in NIH3T3 cells in culture. Biochim Biophys Acta 1532: 128-136. (Pubitemid 32553956)
30. Kim HK, Davaa E, Myung CS, Park JS (2010) Enhanced siRNA delivery using cationic liposomes with new polyarginine-conjugated PEG-lipid. Int J Pharm 392: 141-147.
31. Kinet V, Nguyen NQ, Sabatel C, Blacher S, Noël A, Martial JA, Struman I (2009) Antiangiogenic liposomal gene therapy with 16K human prolactin efficiently reduces tumor growth. Cancer Lett 284: 222-228.
32. Koide H, Asai T, Hatanaka K, Akai S, Ishii T, Kenjo E, Ishida T, Kiwada H, Tsukada H, Oku N (2010) T cell-independent B cell response is responsible for ABC phenomenon induced by repeated injection of PEGylated liposomes. Int J Pharm 392: 218-223.
33. Koltover I, Salditt T, Rädler JO, Safinya CR (1998) An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery. Science 281: 78-81. (Pubitemid 28354046)
34. Koumbi D, Clement JC, Sideratou Z, Yaouanc JJ, Loukopoulos D, Kollia P (2006) Factors mediating lipofection potency of a series of cationic phosphonolipids in human cell lines. Biochim Biophys Acta 1760: 1151-1159. (Pubitemid 43928256)
35. Kundu PP, Sharma V (2008) Synthetic polymeric vectors in gene therapy. Curr Opin Solid State Mater Sci 12: 89-102.
36. Labbé JF, Cronier F, C-Gaudreault R, Auger M (2009) Spectroscopic characterization of DMPC/DOTAP cationic liposomes and their interactions with DNA and drugs. Chem Phys Lipids 158: 91-101.
37. Li S, Tseng WC, Stolz DB, Wu SP, Watkins SC, Huang L (1999) Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection. Gene Ther 6: 585-594. (Pubitemid 29192667)
38. Mahato RI (2005)Water insoluble and soluble lipids for gene delivery. Adv Drug Deliv Rev 57:699-712.
39. Maitani Y, Igarashi S, Sato M, Hattori Y (2007) Cationic liposome (DC-Chol/DOPE = 1:2) and a modified ethanol injection method to prepare liposomes, increased gene expression. Int J Pharm 342: 33-39. (Pubitemid 47259323)
40. Malone RW, Felgner PL, Verma IM (1989) Cationic liposome-mediated RNA transfection. Proc Natl Acad Sci 86: 6077-6081. (Pubitemid 19210605)
41. Masotti A, Mossa G, Cametti C, Ortaggi G, Bianco A, Grosso ND, Malizia D, Esposito C (2009) Comparison of different commercially available cationic liposome-DNA lipoplexes: Parameters influencing toxicity and transfection efficiency. Colloids Surf B Biointerfaces 68: 136-144.
42. Meng M, Liu Y, Wang YB, Wang JC, Zhang H, Wang XQ, Zhang X, Lu WL, Zhang Q (2008) Increase of the pharmacological and pharmacokinetic efficacy of negatively charged polypeptide recombinant hirudin in rats via parenteral route by association with cationic liposomes. J Control Release 128: 113-119.
43. Mével M, Kamaly N, Carmona S, Oliver MH, Jorgensen MR, Crowther C, Salazar FH, Marion PL, Fujino M, Natori Y, Thanou M, Arbuthnot P, Yaouanc JJ, Jaffrès PA, Miller AD (2010) DODAG; a versatile new cationic lipid that mediates efficient delivery of pDNA and siRNA. J Control Release 143: 222-232.
44. Miller AD (2004) Towards safe nanoparticle technologies for nucleic acid therapeutics. Tumori 94: 234-245.
45. Obata Y, Suzuki D, Takeoka S (2008) Evaluation of cationic assemblies constructed with amino-acid based lipids for plasmid DNA delivery. Bioconjug Chem 19: 55-63.
46. Obata Y, Ciofani G, Raffa V, Cuschieri A, Menciassi A, Dario P, Takeoka S (2010) Evaluation of cationic liposomes composed of an amino acid-based lipid for neuronal transfection. Nanomedicine 6: 70-77.
47. Oliveira AC, Ferraz MP, Monteiro FJ, Simões S (2009) Cationic liposome-DNA complexes as gene delivery vectors: Development and behaviour towards bone-like cells. Acta Biomater 5: 2142-2151.
48. Papahadjopoulos D, Poste G, Schaeffer BE (1973) Fusion of mammalian cells by unilamellar lipid vesicles: influence of lipid surface charge, fluidity and cholesterol. Biochim Biophys Acta 323: 23-42.
49. Penacho N, Rosa M, Lindman B, Miguel MG, Simões S, de Lima MC (2010) Physicochemical properties of transferrin-associated lipopolyplexes and their role in biological activity. Colloids Surf B Biointerfaces 76: 207-214.
50. Plank C, Mechtler K, Szoka FC, Wagner E (1996) Activation of the complement system by synthetic pDNA complexes: a potential barrier for intravenous gene delivery. Hum Gene Ther 7: 1437-1446. (Pubitemid 26293564)
51. Radchatawedchakoon W, Watanapokasin R, Krajarng A, Yingyongnarongkul BE (2010) Solid phase synthesis of novel asymmetric hydrophilic head cholesterol-based cationic lipids with potential DNA delivery. Bioorg Med Chem 18: 330-342.
52. Rädler JO, Koltover I, Salditt T, Safinya CR (1997) Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes. Science 275: 810-814. (Pubitemid 27074877)
53. Ramezani M, Khoshhamdam M, Dehshahri A, Malaekeh-Nikouei B (2009) The influence of size, lipid composition and bilayer fluidity of cationic liposomes on the transfection efficiency of nanolipoplexes. Collo Surf B: Biointerfaces 72: 1-5.
54. Remaut K, Lucas B, Braeckmans K, Demeester J, De Smedt SC (2007) Pegylation of liposomes favours the endosomal degradation of the delivered phosphodiester oligonucleotides. J Control Release 117: 256-266. (Pubitemid 46161877)
55. Remaut K, Lucas B, Braeckmans K, Sanders NN, Demeester J, De Smedt SC (2006) Delivery of phosphodiester oligonucleotides: Can DOTAP/DOPE liposomes do the trick? Biochemistry 45: 1755-1764.
56. Ross PC, Hui SW (1999) Lipoplex size is a major determinant of in vitro lipofection efficiency. Gene Ther 6: 651-659.
57. Safinya CR, Ewert K, Ahmad A, Evans HM, Raviv U, Needleman DJ, Lin AJ, Slack NL, George C, Samuel CE (2006) Crystal science to gene delivery applications DNA complexes: from liquid-Cationic liposome. Philos Transact A Math Phys Eng Sci 364: 2573-2596. (Pubitemid 44661774)
58. Santos AO, da Silva LC, Bimbo LM, de Lima MC, Simões S, Moreira JN (2010) Design of peptide-targeted liposomes containing nucleic acids. Biochim Biophys Acta 1798: 433-441.
59. Simões S, Filipe A, Faneca H, Mano M, Penacho N, Düzgünes N, Pedroso de Lima MC (2005) Cationic liposomes for gene delivery. Expert Opin. Drug Deliv 2: 237-254. (Pubitemid 41135785)
60. Song LY, Ahkong QF, Rong Q, Wang Z, Ansell S, Hope MJ, Mui B (2002) Characterization of the inhibitory effect of PEG-lipid conjugates on the intracellular delivery of plasmid and antisense DNA mediated by cationic lipid liposomes. Biochim Biophys Acta 1558: 1-13. (Pubitemid 34031950)
61. Stegmann T, Legendre JY (1997) Gene transfer mediated by cationic lipids: lack of a correlation between lipid mixing and transfection. Biochim Biophys Acta 1325: 71-79. (Pubitemid 27138477)
62. Sun Y, Sun D, Li F, Tian L, Li C, Li L, Lin R, Wang S (2007) Downregulation of Sirt1 by antisense oligonucleotides induces apoptosis and enhances radiation sensitization in A549 lung cancer cells. Lung Cancer 58: 21-29. (Pubitemid 47385929)
63. Tagami T, Nakamura K, Shimizu T, Ishida T, Kiwada H (2009) Effect of siRNA in PEG-coated siRNA-lipoplex on anti-PEG IgM production. J Control Release 137: 234-240.
64. Tatsuhiro Ishida, Hiroshi Kiwada (2008) Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes. Int J Pharm 354: 56-62.
65. Weisman S, Hirsch-Lerner D, Barenholz Y, Talmon Y (2004) Nanostructure of Cationic Lipid-Oligonucleotide Complexes. Biophys J. 87: 609-614. (Pubitemid 38885700)
66. Xiao W, Chen X, Yang L, Mao Y, Wei Y, Chen L (2010) Co-delivery of doxorubicin and plasmid by a novel FGFR-mediated cationic liposome. Int J Pharm 393: 119-126.
67. Xu H, Wang KQ, Deng YH, Chen da W (2010) Effects of cleavable PEG-holesterol derivatives on the accelerated blood clearance of PEGylated liposomes. Biomaterials 31: 4757-4763.
68. Xu L, and Anchordoquy TJ (2008) Cholesterol domains in cationic lipid/DNA complexes improve transfection. Biochim Biophys Acta 1778: 2177-2181.
69. Yamamoto A, Kormann M, Rosenecker J, Rudolph C (2009) Current prospects for mRNA gene delivery. Eur J Pharm Biopharm 71: 484-489.
70. Zhang Y, Li H, Sun J, Gao J, Liu W, Li B, Guo Y, Chen J (2010) DC-hol/DOPE cationic liposomes: A comparative study of the influence factors on plasmid pDNA and siRNA gene delivery. Int J Pharm 390: 198-207.
71. Zhang Y, Rong Qi X, Gao Y, ei L, Maitani Y, Nagai T (2007) Mechanisms of co-modified liver-targeting liposomes as gene delivery carriers based on cellular uptake and antigens inhibition effect. J Control Release 117: 281-290.