Mechanisms of co-modified liver-targeting liposomes as gene delivery carriers based on cellular uptake and antigens inhibition effect

Journal of Controlled Release

Volumn 117, Issue 2, 2007, Pages 281-290

  Zhang, Yuan ^a   Rong Qi, Xian ^a   Gao, Yan ^b   Wei, Lai ^b   Maitani, Yoshie ^c   Nagai, Tsuneji ^c  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^c HOSHI UNIVERSITY   (Japan)

Author keywords

sitosterol d glucoside; Co modified cationic liposomes; Endocytosis; Liver targeting; Membrane fusion

Indexed keywords

ANTIGENS; BIOLOGICAL ORGANS; CONTROLLED DRUG DELIVERY; CYTOLOGY; ENZYME INHIBITION; GENES;

CO-MODIFIED CATIONIC LIPOSOMES; ENDOCYTOSIS; LIVER-TARGETING; MEMBRANE FUSION;

LIPIDS;

ANTISENSE OLIGONUCLEOTIDE; ASIALOGLYCOPROTEIN RECEPTOR; LIPOSOME; POLIDOCANOL; SITOGLUSIDE;

ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; ENDOCYTOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE DELIVERY SYSTEM; GENE TARGETING; GENETIC TRANSFECTION; HEPATITIS B; HEPATITIS B VIRUS; HETEROZYGOTE; HUMAN; HUMAN CELL; IMMUNOASSAY; INHIBITION KINETICS; LIVER CELL; MEMBRANE FUSION; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN MODIFICATION; TARGET ORGAN;

ALPHA-FETOPROTEINS; ANDROSTADIENES; ANIMALS; ASIALOGLYCOPROTEINS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL SURVIVAL; ENDOCYTOSIS; ENDOSOMES; FLUORESCEIN-5-ISOTHIOCYANATE; HEPATITIS B; HEPATITIS B ANTIGENS; HEPATITIS B VIRUS; HEPATOCYTES; HUMANS; LIPOSOMES; LIVER; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; NIGERICIN; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; POLYETHYLENE GLYCOLS; RATS; TRANSFECTION;

EID: 33846547610     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.11.006     Document Type: Article

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