-
1
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
DOI 10.1038/35102167
-
Reya T, Morrison SJ, Clarke MF, Weissman IL: Stem cells, cancer, and cancer stem cells. Nature 2001;414:105-111. (Pubitemid 33041634)
-
(2001)
Nature
, vol.414
, Issue.6859
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
2
-
-
33750313208
-
Cancer stem cells - Perspectives on current status and future directions: AACR workshop on cancer stem cells
-
DOI 10.1158/0008-5472.CAN-06-3126
-
Clarke MF, Dick JE, Dirks P, Eaves C, Jamieson CH, Jones DL, Visvader IL, Weissman IL, Wahl GM: Cancer stem cells - perspectives on current status and future directions: AACR workshop on cancer stem cells. Cancer Res 2006;66:9339-9344. (Pubitemid 44623625)
-
(2006)
Cancer Research
, vol.66
, Issue.19
, pp. 9339-9344
-
-
Clarke, M.F.1
Dick, J.E.2
Dirks, P.B.3
Eaves, C.J.4
Jamieson, C.H.M.5
Jones, D.L.6
Visvader, J.7
Weissman, I.L.8
Wahl, G.M.9
-
3
-
-
0021242388
-
Tumor heterogeneity
-
Heppner GH: Tumor heterogeneity. Cancer Res 1984;44:2259-2265. (Pubitemid 14110633)
-
(1984)
Cancer Research
, vol.44
, Issue.6
, pp. 2259-2265
-
-
Heppner, G.H.1
-
4
-
-
34047096557
-
Cancer stem cells: Models and concepts
-
DOI 10.1146/annurev.med.58.062105.204854
-
Dalerba P, Cho RW, Clarke MF: Cancer stem cells: models and concepts. Annu Rev Med 2007;58:267-284. (Pubitemid 46706514)
-
(2007)
Annual Review of Medicine
, vol.58
, pp. 267-284
-
-
Dalerba, P.1
Cho, R.W.2
Clarke, M.F.3
-
5
-
-
52549087785
-
Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
-
Visvader JE, Lindeman GJ: Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 2008;8:755-768.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
6
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
DOI 10.1038/nm0797-730
-
Bonnet D, Dick JE: Human acute myeloid leukemia is organized as hierachy that originates from a primitve hematopoietic cell. Nat Med 1997;3:730-737. (Pubitemid 27298715)
-
(1997)
Nature Medicine
, vol.3
, Issue.7
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
7
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
DOI 10.1073/pnas.0530291100
-
Al-Hajj M, Wicha M, Benito-Hernandez A, Morrison S, Clarke M: Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003;100:3983-3988. (Pubitemid 36418143)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
8
-
-
70350754364
-
Cancer stem cells in solid tumors
-
Er O: Cancer stem cells in solid tumors. Onkologie 2009;32:605-609.
-
(2009)
Onkologie
, vol.32
, pp. 605-609
-
-
Er, O.1
-
9
-
-
28244472369
-
Prospective identification of tumorigenic prostate cancer stem cells
-
DOI 10.1158/0008-5472.CAN-05-2018
-
Collins AT, Berry PA, Hyde C, Stower M, Maitland N: Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 2005;65:10946-10951. (Pubitemid 41713363)
-
(2005)
Cancer Research
, vol.65
, Issue.23
, pp. 10946-10951
-
-
Collins, A.T.1
Berry, P.A.2
Hyde, C.3
Stower, M.J.4
Maitland, N.J.5
-
10
-
-
0020577072
-
A cell-surface molecule involved in organ-specific homing of lymphocytes
-
Gallantin W, Weissmann I, Butcher E: A cell surface molecule involved in organ specific homing of lymphocytes. Nature 1983;304:30-34. (Pubitemid 13063101)
-
(1983)
Nature
, vol.304
, Issue.5921
, pp. 30-34
-
-
Gallatin, W.M.1
Weissman, I.L.2
Butcher, E.C.3
-
11
-
-
59249094144
-
CD44 and EpCAM: Cancer-initiating cell markers
-
Marhaba R, Klingbeil P, Nuebel T, Nazarenko I, Buechler MW, Zoeller M: CD44 and EpCAM: cancer-initiating cell markers. Curr Mol Med 2008;8:784-804.
-
(2008)
Curr Mol Med
, vol.8
, pp. 784-804
-
-
Marhaba, R.1
Klingbeil, P.2
Nuebel, T.3
Nazarenko, I.4
Buechler, M.W.5
Zoeller, M.6
-
12
-
-
33846512398
-
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
-
DOI 10.1073/pnas.0610117104
-
Prince ME, Sivanandan R, Kaczorowski A, Wolf GT, Kaplan MJ, Dalerba P, Weissman IL, Clarke MF, Ailles LE: Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci USA 2007;104:973-978. (Pubitemid 46154721)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.3
, pp. 973-978
-
-
Prince, M.E.1
Sivanandan, R.2
Kaczorowski, A.3
Wolf, G.T.4
Kaplan, M.J.5
Dalerba, P.6
Weissman, I.L.7
Clarke, M.F.8
Ailles, L.E.9
-
13
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li CW, Heidt D, Dalerba P, Burant C, Zhang L, Adsay V, Wicha MS, Clarke MF, Simeone DM: Identification of pancreatic cancer stem cells. Cancer Res 2007;67:1030-1037.
-
(2007)
Cancer Res
, vol.67
, pp. 1030-1037
-
-
Li, C.W.1
Heidt, D.2
Dalerba, P.3
Burant, C.4
Zhang, L.5
Adsay, V.6
Wicha, M.S.7
Clarke, M.F.8
Simeone, D.M.9
-
14
-
-
34547193404
-
Phenotypic characterization of human colorectal cancer stem cells
-
DOI 10.1073/pnas.0703478104
-
Dalerba P, Dylla SJ, Park I, Liu R, Wang X, Cho RW, Hoey T, Gurney A, Huang EH, Simeone DM, Shelton AA, Parmiani G, Castelli Ch, Clarke MF: Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci USA 2007;104:10158-10163. (Pubitemid 47175279)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.24
, pp. 10158-10163
-
-
Dalerba, P.1
Dylla, S.J.2
Park, I.-K.3
Liu, R.4
Wang, X.5
Cho, R.W.6
Hoey, T.7
Gurney, A.8
Huang, E.H.9
Simeone, D.M.10
Shelton, A.A.11
Parmiani, G.12
Castelli, C.13
Clarke, M.F.14
-
17
-
-
77950561915
-
CD44, a therapeutic target for metastasising tumours
-
Orian-Rousseau V: CD44, a therapeutic target for metastasising tumours. Eur J Cancer 2010;46:1271-1277.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1271-1277
-
-
Orian-Rousseau, V.1
-
18
-
-
58149269566
-
CD44 is of functional importance for colorectal cancer stem cells
-
Du L, Wang H, He L, Zhang J, Ni B, Wang X, Hoey T, Gurney A, Huang EH, Simeone DM, Shelton AA, Parmiani G, Castelli Ch, Clarke MF: CD44 is of functional importance for colorectal cancer stem cells. Hum Cancer Biol 2008;14:6751-6760.
-
(2008)
Hum Cancer Biol
, vol.14
, pp. 6751-6760
-
-
Du, L.1
Wang, H.2
He, L.3
Zhang, J.4
Ni, B.5
Wang, X.6
Hoey, T.7
Gurney, A.8
Huang, E.H.9
Simeone, D.M.10
Shelton, A.A.11
Parmiani, G.12
Castelli, Ch.13
Clarke, M.F.14
-
19
-
-
50049134725
-
Phase i trial with the mertansine in head and neck squamous cell carcinoma
-
Riechelmann H, Sauter A, Golze W, Hanft G, Schroen C, Hoermann K, Erhardt T, Gronau S: Phase I trial with the mertansine in head and neck squamous cell carcinoma. Oral Oncol 2008;44:823-829.
-
(2008)
Oral Oncol
, vol.44
, pp. 823-829
-
-
Riechelmann, H.1
Sauter, A.2
Golze, W.3
Hanft, G.4
Schroen, C.5
Hoermann, K.6
Erhardt, T.7
Gronau, S.8
-
21
-
-
4444251520
-
CD133 positive endothelial progenitor cells contribute to the tumour vasculature in non-small cell lung cancer
-
DOI 10.1136/jcp.2004.016444
-
Hilbe W, Dirnhofer S, Oberwasserlechne F, Schmid T, Gunsilius E, Hilbe G, Wöll E, Kähler CM: CD133 positive endothelial progenitor cells contribute to the tumour vasculature in non-small cell lung cancer. J Clin Pathol 2004;57:965-969. (Pubitemid 39208249)
-
(2004)
Journal of Clinical Pathology
, vol.57
, Issue.9
, pp. 965-969
-
-
Hilbe, W.1
Dirnhofer, S.2
Oberwasserlechner, F.3
Schmid, T.4
Gunsilius, E.5
Hilbe, G.6
Woll, E.7
Kahler, C.M.8
-
22
-
-
77952307758
-
Prominin-1 a distinct cholesterol-binding membrane protein and the organization of the apical plasma membrane of epithelial cells
-
Corbeil D, Marzesco A, Fargeas CA, Huttner WB: Prominin-1 a distinct cholesterol-binding membrane protein and the organization of the apical plasma membrane of epithelial cells. Subcell Biochem 2010;51:399-423.
-
(2010)
Subcell Biochem
, vol.51
, pp. 399-423
-
-
Corbeil, D.1
Marzesco, A.2
Fargeas, C.A.3
Huttner, W.B.4
-
23
-
-
46949094014
-
New insights into the cell biology of hematopoietic progenitors by studying prominin-1 (CD133)
-
DOI 10.1159/000112847
-
Bauer N, Fonseca A, Florek M, Freund D, Jaszai J, Bornhauser M, Fargeas CA, Corbeil D: New insights into cell biology of hematopoietic progenitors by studying prominin-1 (CD133). Cells Tissues Organs 2008;188:127-138. (Pubitemid 351962236)
-
(2008)
Cells Tissues Organs
, vol.188
, Issue.1-2
, pp. 127-138
-
-
Bauer, N.1
Fonseca, A.-V.2
Florek, M.3
Freund, D.4
Jaszai, J.5
Bornhauser, M.6
Fargeas, C.A.7
Corbeil, D.8
-
24
-
-
49749144107
-
The utility and limitations of glycosylated human CD133 epitopes in defining cancer stem cells
-
Bidlingmaier S, Zhu X, Liu B: The utility and limitations of glycosylated human CD133 epitopes in defining cancer stem cells. J Mol Med 2008;86: 1025-1032.
-
(2008)
J Mol Med
, vol.86
, pp. 1025-1032
-
-
Bidlingmaier, S.1
Zhu, X.2
Liu, B.3
-
25
-
-
39449088496
-
Identification and expansion of the tumorigenic lung cancer stem cell population
-
DOI 10.1038/sj.cdd.4402283, PII 4402283
-
Eramo A, Lotti F, Sette G, Pilozzi E, Biffoni M, Di Virgilio A, Conticello C, Ruco L, Peschle C, De Maria R: Identification and expansion of the tumorigenic lung cancer stem cell population. Cell Death Differ 2008;15:504-514. (Pubitemid 351267301)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.3
, pp. 504-514
-
-
Eramo, A.1
Lotti, F.2
Sette, G.3
Pilozzi, E.4
Biffoni, M.5
Di Virgilio, A.6
Conticello, C.7
Ruco, L.8
Peschle, C.9
De Maria, R.10
-
26
-
-
34548455927
-
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
-
DOI 10.1016/j.stem.2007.06.002, PII S1934590907000665
-
Hermann PC, Huber S, Herrler T, Aicher A, Ellwart J, Guba M, Bruns CJ, Heeschen C: Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 2007;1:313-323. (Pubitemid 47355323)
-
(2007)
Cell Stem Cell
, vol.1
, Issue.3
, pp. 313-323
-
-
Hermann, P.C.1
Huber, S.L.2
Herrler, T.3
Aicher, A.4
Ellwart, J.W.5
Guba, M.6
Bruns, C.J.7
Heeschen, C.8
-
27
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
DOI 10.1038/nature05372, PII NATURE05372
-
Brien CA, Pollett A, Gallinger S, Dick JE: A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007;445:106-110. (Pubitemid 46067310)
-
(2007)
Nature
, vol.445
, Issue.7123
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
28
-
-
34249980343
-
Identification and characterization of tumorigenic liver cancer stem/progenitor cells
-
DOI 10.1053/j.gastro.2007.04.025, PII S001650850700786X
-
Ma S, Chan K, Hu L, Lee T, Wo J, Ng I, Zheng BJ, Guan XY: Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology 2007;132:2542-2556. (Pubitemid 46890873)
-
(2007)
Gastroenterology
, vol.132
, Issue.7
, pp. 2542-2556
-
-
Ma, S.1
Chan, K.2
Hu, L.3
Lee, T.K.4
Wo, J.Y.5
Ng, I.O.6
Zheng, B.7
Guan, X.8
-
29
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
DOI 10.1038/nature03128
-
Singh S, Hawkins C, Clarke I, Squire J, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB: Identification of human brain tumour initiating cells. Nature 2004;432:396-401. (Pubitemid 39551674)
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
30
-
-
62349116134
-
In vivo imaging, tracking, and targeting of cancer stem cells
-
Vlashi E, Kim K, Lagadec C, Donna LD, Mcdonald JT, Eghbali M, Sayre JW, Stefani E, Mcbride W, Pajonk F: In vivo imaging, tracking, and targeting of cancer stem cells. J Natl Cancer Inst 2009;101:350-359.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 350-359
-
-
Vlashi, E.1
Kim, K.2
Lagadec, C.3
Donna, L.D.4
McDonald, J.T.5
Eghbali, M.6
Sayre, J.W.7
Stefani, E.8
McBride, W.9
Pajonk, F.10
-
31
-
-
77953900746
-
A biological global positioning system: Considerations for tracking stem cell behaviors in the whole body
-
Li SC, May L, Tachiki L, Luo J, Dethlefs BA, Chen Z, Loudon GW: A biological global positioning system: considerations for tracking stem cell behaviors in the whole body. Stem Cell Rev 2010;6:317-333.
-
(2010)
Stem Cell Rev
, vol.6
, pp. 317-333
-
-
Li, S.C.1
May, L.2
Tachiki, L.3
Luo, J.4
Dethlefs, B.A.5
Chen, Z.6
Loudon, G.W.7
-
32
-
-
9344229796
-
In vivo tracking of stem cells for clinical trials in cardiovascular disease
-
DOI 10.1161/01.CIR.0000149840.46523.FC
-
Frangioni J, Hajjar R: In vivo tracking of stem cells for clinical trials in cardiovascular disease. Circulation 2004;110:3378-3383. (Pubitemid 39557503)
-
(2004)
Circulation
, vol.110
, Issue.21
, pp. 3378-3383
-
-
Frangioni, J.V.1
Hajjar, R.J.2
-
33
-
-
73449125723
-
Cancer stem cells, endothelial progenitors, and mesenchymal stem cells: 'Seed and Soil' theory revisited
-
Lin EH, Jiang Y, Deng Y, Lapsiwala R, Lin T, Blau C: Cancer stem cells, endothelial progenitors, and mesenchymal stem cells: 'Seed and Soil' theory revisited. Gastrointest Cancer Res 2008;2:169-174.
-
(2008)
Gastrointest Cancer Res
, vol.2
, pp. 169-174
-
-
Lin, E.H.1
Jiang, Y.2
Deng, Y.3
Lapsiwala, R.4
Lin, T.5
Blau, C.6
-
34
-
-
70349479538
-
Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment
-
Bertolini G, Roz L, Perego P, Tortoreto M, Fontanella E, Gatti L, Pratesi G, Fabbri A, Andriani F, Tinelli S, Roz E, Caserini R, Lo Vullo S, Camerini T, Mariani L, Delia D, Calabro E, Pastorino U, Sozzi G: Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment. Proc Natl Acad Sci USA 2009;106:16281-16286.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16281-16286
-
-
Bertolini, G.1
Roz, L.2
Perego, P.3
Tortoreto, M.4
Fontanella, E.5
Gatti, L.6
Pratesi, G.7
Fabbri, A.8
Andriani, F.9
Tinelli, S.10
Roz, E.11
Caserini, R.12
Lo Vullo, S.13
Camerini, T.14
Mariani, L.15
Delia, D.16
Calabro, E.17
Pastorino, U.18
Sozzi, G.19
-
35
-
-
34547113747
-
Tumor growth need not be driven by rare cancer stem cells
-
DOI 10.1126/science.1142596
-
Kelly PN, Dakic A, Adamas J, Nutt S, Strasser A: Tumor growth need not be driven by rare cancer stem cells. Science 2007;317:337. (Pubitemid 47106366)
-
(2007)
Science
, vol.317
, Issue.5836
, pp. 337
-
-
Kelly, P.N.1
Dakic, A.2
Adams, J.M.3
Nutt, S.L.4
Strasser, A.5
-
36
-
-
45549097925
-
Cancer stem cells and the ontogeny of lung cancer
-
Peacock CD, Watkins DN: Cancer stem cells and the ontogeny of lung cancer. J Clin Oncol 2008;26: 2883-2889.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2883-2889
-
-
Peacock, C.D.1
Watkins, D.N.2
-
37
-
-
77954844712
-
Novel roles for Notch, Wnt and Hedgehog in hematopoiesis derived from human pluripotent stem cells
-
Cerdan C, Bhatia M: Novel roles for Notch, Wnt and Hedgehog in hematopoiesis derived from human pluripotent stem cells. Int J Dev Biol 2010; 54:955-963.
-
(2010)
Int J Dev Biol
, vol.54
, pp. 955-963
-
-
Cerdan, C.1
Bhatia, M.2
-
39
-
-
33750686955
-
The Hedgehog signaling pathway in cancer
-
DOI 10.1158/1078-0432.CCR-06-1736
-
Evangelista M, Tian H, Sauvage FJ: The Hedgehog signaling pathway in cancer. Clin Cancer Res 2006;12:5924-5928. (Pubitemid 44703749)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.20 PART 1
, pp. 5924-5928
-
-
Evangelista, M.1
Tian, H.2
De Sauvage, F.J.3
-
40
-
-
33644782668
-
Recent insights into the role of Notch signaling in tumorigenesis
-
DOI 10.1182/blood-2005-08-3329
-
Leong KG, Karsan A: Recent insights into the role of Notch signaling in tumorigenesis. Cancer Res 2006;107:2223-2233. (Pubitemid 43345539)
-
(2006)
Blood
, vol.107
, Issue.6
, pp. 2223-2233
-
-
Leong, K.G.1
Karsan, A.2
-
41
-
-
76349104842
-
Wnt/b-catenin signaling regulates cancer stem cells in lung cancer A549 cells
-
Teng Y, Wang X, Wang Y, Ma D: Wnt/b-catenin signaling regulates cancer stem cells in lung cancer A549 cells. Biochem Biophys Res Commun 2010;392:373-379.
-
(2010)
Biochem Biophys Res Commun
, vol.392
, pp. 373-379
-
-
Teng, Y.1
Wang, X.2
Wang, Y.3
Ma, D.4
-
42
-
-
33745728170
-
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
-
Liu S, Dontu G, Mantle ID, Patel S, Ahn N, Jackson KW, Suri P, Wicha MS: Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res 2006;66:6063-6071.
-
(2006)
Cancer Res
, vol.66
, pp. 6063-6071
-
-
Liu, S.1
Dontu, G.2
Mantle, I.D.3
Patel, S.4
Ahn, N.5
Jackson, K.W.6
Suri, P.7
Wicha, M.S.8
-
43
-
-
33847022189
-
Frequent requirement of Hedgehog signaling in nonsmall cell lung carcinoma
-
Yuan Z, Goetz J, Singh S, Ogden S, Petty W, Black C, Memoli VA, Dmitrovsky E, Robbins DJ: Frequent requirement of Hedgehog signaling in nonsmall cell lung carcinoma. Oncogene 2007;26:1046-1055.
-
(2007)
Oncogene
, vol.26
, pp. 1046-1055
-
-
Yuan, Z.1
Goetz, J.2
Singh, S.3
Ogden, S.4
Petty, W.5
Black, C.6
Memoli, V.A.7
Dmitrovsky, E.8
Robbins, D.J.9
-
44
-
-
67849124654
-
DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency
-
Hoey T, Yen W, Axelrod F, Basi J, Donigian L, Dylla S, Fitch-Bruhns M, Lazetic S, Park IK, Sato A, Styal S, Wang X, Clarke MF, Lewicki J, Gurney A: DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency. Cell Stem Cell 2009;5:168-177.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 168-177
-
-
Hoey, T.1
Yen, W.2
Axelrod, F.3
Basi, J.4
Donigian, L.5
Dylla, S.6
Fitch-Bruhns, M.7
Lazetic, S.8
Park, I.K.9
Sato, A.10
Styal, S.11
Wang, X.12
Clarke, M.F.13
Lewicki, J.14
Gurney, A.15
-
45
-
-
79955771397
-
Cancer stem cells problems for therapy?
-
Alison MR, Lim S, Nicholoson L: Cancer stem cells: problems for therapy? J Pathol 2010;223:147-161.
-
(2010)
J Pathol
, vol.223
, pp. 147-161
-
-
Alison, M.R.1
Lim, S.2
Nicholoson, L.3
-
46
-
-
38349165576
-
Identification of cells initiating human melanomas
-
Schatton T, Murphy GF, Frank NY, Yamaura K, Waaga-Gasser AM, Gasser M, Zhan Q, Jordan S, Duncan LM, Weishaupt C, Fuhlbrigge RC, Kupper TS, Sayegh MH, Frank MH: Identification of cells initiating human melanomas. Nature 2008;451:345-349.
-
(2008)
Nature
, vol.451
, pp. 345-349
-
-
Schatton, T.1
Murphy, G.F.2
Frank, N.Y.3
Yamaura, K.4
Waaga-Gasser, A.M.5
Gasser, M.6
Zhan, Q.7
Jordan, S.8
Duncan, L.M.9
Weishaupt, C.10
Fuhlbrigge, R.C.11
Kupper, T.S.12
Sayegh, M.H.13
Frank, M.H.14
-
47
-
-
3042655528
-
Membrane transporters and channels: Role of the transportome in cancer chemosensitivity and chemoresistance
-
DOI 10.1158/0008-5472.CAN-03-3884
-
Huang Y: Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance. Cancer Res 2004;64:4294-4301. (Pubitemid 38802436)
-
(2004)
Cancer Research
, vol.64
, Issue.12
, pp. 4294-4301
-
-
Huang, Y.1
Anderle, P.2
Bussey, K.J.3
Barbacioru, C.4
Shankavaram, U.5
Dai, Z.6
Reinhold, W.C.7
Papp, A.8
Weinstein, J.N.9
Sadee, W.10
-
48
-
-
77953663505
-
Antibodies targeting cancer stem cells: A new paradigm in immunotherapy?
-
Deonarain MP, Kousparou CA, Epenetos AA: Antibodies targeting cancer stem cells: a new paradigm in immunotherapy? MAbs 2009;1:12-25.
-
(2009)
MAbs
, vol.1
, pp. 12-25
-
-
Deonarain, M.P.1
Kousparou, C.A.2
Epenetos, A.A.3
-
49
-
-
68749099671
-
Identification of selective inhibitors of cancer stem cells by high-throughput screening
-
Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, Lander ES: Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 2009;138:645-659.
-
(2009)
Cell
, vol.138
, pp. 645-659
-
-
Gupta, P.B.1
Onder, T.T.2
Jiang, G.3
Tao, K.4
Kuperwasser, C.5
Weinberg, R.A.6
Lander, E.S.7
-
50
-
-
67649983452
-
Hegehhog- Gli signaling pathway inhibitors as anticancer agents
-
Mahindroo N, Punchihewa C, Fujii N: Hegehhog- Gli signaling pathway inhibitors as anticancer agents. J Med Chem 2010;52:3829-3845.
-
(2010)
J Med Chem
, vol.52
, pp. 3829-3845
-
-
Mahindroo, N.1
Punchihewa, C.2
Fujii, N.3
-
51
-
-
70349238733
-
Inhibition of the Hedgehog pathway in advanced basal-cell carcinoma
-
Von Hoff D, LoRusso P, Rudin C, Reddy J, Yauch R, Tibes R, Weiss GJ, Borad MJ, Hann CL, Brahmer JR, Mackey HM, Lum BL, Darbonne WC, Marsters JC Jr, de Sauvage FJ, Low JA: Inhibition of the Hedgehog pathway in advanced basal-cell carcinoma. N Engl J Med 2009;361:1164-1172.
-
(2009)
N Engl J Med
, vol.361
, pp. 1164-1172
-
-
Von Hoff, D.1
Lorusso, P.2
Rudin, C.3
Reddy, J.4
Yauch, R.5
Tibes, R.6
Weiss, G.J.7
Borad, M.J.8
Hann, C.L.9
Brahmer, J.R.10
MacKey, H.M.11
Lum, B.L.12
Darbonne, W.C.13
Marsters Jr., J.C.14
De Sauvage, F.J.15
Low, J.A.16
-
52
-
-
70349244812
-
Treatment of medulloblastoma with Hedgehog pathway inhibitor GDC-0449
-
Rudin C, Hann C, Laterra J, Yauch R, Callahan C, Fu L, Holcomb T, Stinson J, Gould SE, Coleman B, LoRusso PM, Von Hoff DD, de Sauvage FJ, Low JA: Treatment of medulloblastoma with Hedgehog pathway inhibitor GDC-0449. N Engl J Med 2009;361:1173-1178.
-
(2009)
N Engl J Med
, vol.361
, pp. 1173-1178
-
-
Rudin, C.1
Hann, C.2
Laterra, J.3
Yauch, R.4
Callahan, C.5
Fu, L.6
Holcomb, T.7
Stinson, J.8
Gould, S.E.9
Coleman, B.10
Lo Russo, P.M.11
Von Hoff, D.D.12
De Sauvage, F.J.13
Low, J.A.14
-
53
-
-
75349105363
-
Notch pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
-
Fan X, Khaki L, Zhu T, Soules M, Talsma C, Gul N, Koh C, Zhang J, Li YM, Maciaczyk J, Nikkhah G, Dimeco F, Piccirillo S, Vescovi AL, Eberhart CG: Notch pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells 2010;28:5-16.
-
(2010)
Stem Cells
, vol.28
, pp. 5-16
-
-
Fan, X.1
Khaki, L.2
Zhu, T.3
Soules, M.4
Talsma, C.5
Gul, N.6
Koh, C.7
Zhang, J.8
Li, Y.M.9
MacIaczyk, J.10
Nikkhah, G.11
Dimeco, F.12
Piccirillo, S.13
Vescovi, A.L.14
Eberhart, C.G.15
-
55
-
-
27144487469
-
In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog
-
DOI 10.1038/nature03994, PII N03994
-
Ahn S, Joyner A: In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog. Nature 2005;437:894-897. (Pubitemid 41486765)
-
(2005)
Nature
, vol.437
, Issue.7060
, pp. 894-897
-
-
Ahn, S.1
Joyner, A.L.2
-
56
-
-
0242669237
-
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
-
DOI 10.1038/nature01493
-
Watkins D, Berman D, Burkholder S, Wang B, Beachy P, Baylin S: Hedgehog signalling within airway epithelial progenitors and in small cell lung cancer. Nature 2003;422:313-317. (Pubitemid 36378358)
-
(2003)
Nature
, vol.422
, Issue.6929
, pp. 313-317
-
-
Watkins, D.N.1
Berman, D.M.2
Burkholder, S.G.3
Wang, B.4
Beachy, P.A.5
Baylin, S.B.6
-
57
-
-
0033567213
-
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
-
St-Jacques B, Hammerschmidt M, McMahon A: Indian hedgehog signaling regulates proliferation and differentaton of chondrocytes and is essential for bone formation. Genes Dev 1999;13:2072-2086. (Pubitemid 29407348)
-
(1999)
Genes and Development
, vol.13
, Issue.16
, pp. 2072-2086
-
-
St-Jacques, B.1
Hammerschmidt, M.2
McMahon, A.P.3
-
58
-
-
34247843997
-
Hedgehog signaling pathway and gastrointestinal stem cell signaling network
-
Katoh Y, Katoh M: Hedgehog signaling pathway and gastrointestinal stem cell signaling network. Int J Mol Med 2006;18:1019-1023.
-
(2006)
Int J Mol Med
, vol.18
, pp. 1019-1023
-
-
Katoh, Y.1
Katoh, M.2
-
59
-
-
40149091426
-
Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure
-
DOI 10.1016/j.ccr.2008.01.027, PII S1535610808000378
-
Kimura H, Ng JM, Curran T: Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure. Cancer Cell 2008;13:249-260. (Pubitemid 351324879)
-
(2008)
Cancer Cell
, vol.13
, Issue.3
, pp. 249-260
-
-
Kimura, H.1
Ng, J.M.Y.2
Curran, T.3
-
60
-
-
79951904426
-
Clinical experience with Hedgehog pathway inhibitors
-
Low JA, Sauvage FJ: Clinical experience with Hedgehog pathway inhibitors. J Clin Oncol 2010; 28:5321-5326.
-
(2010)
J Clin Oncol
, vol.28
, pp. 5321-5326
-
-
Low, J.A.1
Sauvage, F.J.2
-
61
-
-
59649085554
-
Angiogenesis: A team effort coordinated by Notch
-
Phng L, Gerhardt H: Angiogenesis: a team effort coordinated by Notch. Dev Cell 2009;16:196-208.
-
(2009)
Dev Cell
, vol.16
, pp. 196-208
-
-
Phng, L.1
Gerhardt, H.2
-
63
-
-
33845621982
-
Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia
-
DOI 10.1016/j.ijrobp.2006.09.037, PII S036030160603207X
-
Blazek ER, Foutch J, Makl G: Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia. Int J Radiat Oncol Biol Phys 2007;67:1-5. (Pubitemid 44959518)
-
(2007)
International Journal of Radiation Oncology Biology Physics
, vol.67
, Issue.1
, pp. 1-5
-
-
Blazek, E.R.1
Foutch, J.L.2
Maki, G.3
-
64
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
DOI 10.1038/nature05236, PII NATURE05236
-
Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland A, Dewhirst MW, Bigner DD, Rich JN: Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006;444:756-760. (Pubitemid 44949604)
-
(2006)
Nature
, vol.444
, Issue.7120
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
65
-
-
77953812049
-
Prediction of local recurrence after radiotherapy in head and neck cancer by expression profiling
-
De Jong M, Pramana J, Lacko M, Peutz-Kootstra C, De-Jong J, Takes R: Prediction of local recurrence after radiotherapy in head and neck cancer by expression profiling. Radiother Oncol 2009;90:62.
-
(2009)
Radiother Oncol
, vol.90
, pp. 62
-
-
De Jong, M.1
Pramana, J.2
Lacko, M.3
Peutz-Kootstra, C.4
De-Jong, J.5
Takes, R.6
-
67
-
-
67649939163
-
The increasing complexity of the cancer stem cell paradigm
-
Rosen JM, Jordan CT: The increasing complexity of the cancer stem cell paradigm. Science 2009;324:1670-1673.
-
(2009)
Science
, vol.324
, pp. 1670-1673
-
-
Rosen, J.M.1
Jordan, C.T.2
-
68
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
Quintana E, Shackleton M, Sabel MS, Fullen DR, Johnson TM, Morrison SJ: Efficient tumour formation by single human melanoma cells. Nature 2008;456:593-599.
-
(2008)
Nature
, vol.456
, pp. 593-599
-
-
Quintana, E.1
Shackleton, M.2
Sabel, M.S.3
Fullen, D.R.4
Johnson, T.M.5
Morrison, S.J.6
-
69
-
-
45749102020
-
- metastatic colon cancer cells initiate tumors
-
DOI 10.1172/JCI34401
-
Shmelkov SV, Butler JM, Hooper AT, Hormigo A, Kushner J, Milde T, St Clair R, Baljevic M, White I, Jin DK, Chadburn A, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, D'Angelica M, Kemeny N, Lyden D, Rafii S: CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors. J Clin Invest 2008; 118:2111-2120. (Pubitemid 351872330)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.6
, pp. 2111-2120
-
-
Shmelkov, S.V.1
Butler, J.M.2
Hooper, A.T.3
Hormigo, A.4
Kushner, J.5
Milde, T.6
St Clair, R.7
Baljevic, M.8
White, I.9
Jin, D.K.10
Chadburn, A.11
Murphy, A.J.12
Valenzuela, D.M.13
Gale, N.W.14
Thurston, G.15
Yancopoulos, G.D.16
D'Angelica, M.17
Kemeny, N.18
Lyden, D.19
Rafii, S.20
more..
-
70
-
-
70449528522
-
Controversies in cancer stem cells
-
Jones RJ: Controversies in cancer stem cells. J Mol Med 2009;87:1077-1078.
-
(2009)
J Mol Med
, vol.87
, pp. 1077-1078
-
-
Jones, R.J.1
|