New insights into the cell biology of hematopoietic progenitors by studying prominin-1 (CD133)

Cells Tissues Organs

Volumn 188, Issue 1-2, 2008, Pages 127-138

  Bauer, Nicola ^a   Fonseca, Ana Violeta ^a   Florek, Mareike ^b   Freund, Daniel ^a   Jászai, József ^a   Bornhäuser, Martin ^b   Fargeas, Christine A ^a   Corbeil, Denis ^a,c  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^c Tissue Engineering Laboratories   (Germany)

Author keywords

Cell division; Cell migration; Hematopoietic stem cells; Plasma membrane; Polarity

Indexed keywords

CD133 ANTIGEN; CD34 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; P SELECTIN GLYCOPROTEIN LIGAND 1; PROTEIN PROMININ 1; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; STROMAL CELL DERIVED FACTOR 1;

CELL DIVISION; CELL MEMBRANE; CELL MIGRATION; CELL POLARITY; CELLULAR DISTRIBUTION; CONFERENCE PAPER; CYTOLOGY; HEMATOPOIETIC STEM CELL; HUMAN; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANTIGENS, CD; GLYCOPROTEINS; HEMATOPOIETIC STEM CELLS; HUMANS; PEPTIDES;

ALIAS;

EID: 46949094014     PISSN: 14226405     EISSN: None     Source Type: Journal    
DOI: 10.1159/000112847     Document Type: Conference Paper

References (91)

1. Adams, G.B., D.T. Scadden (2006) The hematopoietic stem cell in its place. Nat Immunol 7: 333-337.
2. Bauer, N., M. Wilsch-Bräuninger, A.V. Fonseca, D. Freund, T. Baust, M. Bornhäuser, B. Hoflack, W.B. Huttner, D. Corbeil (2007) The stem cell marker prominin-1 (CD133) is released from hematopoietic stem and progenitor cells in association with small membrane vesicles (abstract 1505). International Society for Stem Cell Research (ISSCR) Meeting, Cairns.
3. Beaujean, F. (1997) Methods of CD34+ cell separation: comparative analysis. Transfus Sci 18: 251-261.
4. Beckmann, J., S. Scheitza, P. Wernet, J.C. Fischer, B. Giebel (2007) Asymmetric cell division within the human hematopoietic stem and progenitor cell compartment: Identification of asymmetrically segregating proteins. Blood 109: 5494-5501.
5. Bhatia, M. (2001) AC133 expression in human stem cells. Leukemia 15: 1685-1688.
6. +-purified stem cells. Exp Hematol 33: 713-718.
7. Bonnet, D., J.D. Dick (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nature Med 3: 730-737.
8. Bornhäuser, M., L. Eger, U. Oelschlaegel, S. Auffermann-Gretzinger, A. Kiani, J. Schetelig, T. Illmer, M. Schaich, D. Corbeil, C. Thiede, G. Ehninger (2005) Rapid reconstitution of dendritic cells after allogeneic transplantation of CD133+ selected hematopoietic stem cells. Leukemia 19: 161-165.
9. Brenner, S., M.F. Ryser, N.L. Whiting-Theobald, M. Gentsch, G.F. Linton, H.L. Malech (2007) The late dividing population of gamma-retroviral vector transduced human mobilized peripheral blood progenitor cells contributes most to gene-marked cell engraftment in NOD/SCID mice. Stem Cells 25: 1807-1813.
10. Butcher, E.C., L.J. Picker (1996) Lymphocyte homing and homeostasis. Science 272: 60-66.
11. Cancelas, J.A., M. Jansen, D.A. Williams (2006) The role of chemokine activation of Rac GTPases in hematopoietic stem cell marrow homing, retention, and peripheral mobilization. Exp Hematol 34: 976-985.
12. Corbeil, D., K. Röper, M.J. Hannah, A. Hellwig, W.B. Huttner (1999) Selective localization of the polytopic membrane protein prominin in microvilli of epithelial cells - a combination of apical sorting and retention in plasma membrane protrusions. J Cell Sci 112: 1023-1033.
13. Corbeil, D., K. Röper, A. Hellwig, M. Tavian, S. Miraglia, S.M. Watt, P.J. Simmons, B. Peault, D.W. Buck, W.B. Huttner (2000) The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions. J Biol Chem 275: 5512-5520.
14. Corbeil, D., K. Röper, C.A. Fargeas, A. Joester, W.B. Huttner (2001) Prominin: A story of cholesterol, plasma membrane protrusions and human pathology. Traffic 2: 82-91.
15. Dar, A., O. Kollet, T. Lapidot (2006) Mutual, reciprocal SDF-1/CXCR4 interactions between hematopoietic and bone marrow stromal cells regulate human stem cell migration and development in NOD/SCID chimeric mice. Exp Hematol 34: 967-975.
16. de Wynter, E.A., D. Buck, C. Hart, R. Heywood, L.H. Coutinho, A. Clayton, J.A. Rafferty, D. Burt, G. Guenechea, J.A. Bueren, D. Gagen, L.J. Fairbairn, B.I. Lord, N.G. Testa (1998) CD34+AC133+ cells isolated from cord blood are highly enriched in long-term culture-initiating cells, NOD/SCID-repopulating cells and dendritic cell progenitors. Stem Cells 16: 387-396.
17. Dexter, T.M., T.D. Allen, L.G. Lajtha (1977) Conditions controlling the proliferation of haemopoietic stem cells in vitro. J Cell Physiol 91: 335-344.
18. Dubreuil, V., A.M. Marzesco, D. Corbeil, W.B. Huttner, M. Wilsch-Bräuninger (2007) Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1. J Cell Biol 176: 483-495.
19. Faber, A., C. Roderburg, F. Wein, R. Saffrich, A. Seckinger, K. Horsch, A. Diehlmann, D. Wong, G. Bridger, V. Eckstein, A.D. Ho, W. Wagner (2007) The many facets of SDF-1α, CXCR4 agonists and antagonists on hematopoietic progenitor cells. J Biomed Biotechnol DOI: 10.1155/2007/26065.
20. Fargeas, C.A., D. Corbeil, W.B. Huttner (2003) AC133 antigen, CD133, prominin-1, prominin-2, etc.: prominin family gene products in need of a rational nomenclature. Stem Cells 21: 506-508.
21. Fargeas, C.A., A. Joester, E. Missol-Kolka, A. Hellwig, W.B. Huttner, D. Corbeil (2004) Identification of novel Prominin-1/CD133 splice variants with alternative C-termini and their expression in epididymis and testis. J Cell Sci 117: 4301-4311.
22. Fargeas, C.A., A.V. Fonseca, W.B. Huttner, D. Corbeil (2006) Prominin-1 (CD133): from progenitor cells to human diseases. Future Lipidol 1: 213-225.
23. Fargeas, C.A., W.B. Huttner, D. Corbeil (2007) Nomenclature of prominin-1 (CD133) splice variants - an update. Tiss Antig 69: 602-606.
24. Février, B., G. Raposo (2004) Exosomes: endosomal-derived vesicles shipping extracellular messages. Curr Opin Cell Biol 16: 415-421.
25. Florek, M., M. Haase, A.M. Marzesco, D. Freund, G. Ehninger, W.B. Huttner, D. Corbeil (2005) Prominin-1/CD133, a neural and hematopoietic stem cell marker, is expressed in adult human differentiated cells and certain types of kidney cancer. Cell Tiss Res 319: 15-26.
26. Florek, M., N. Bauer, P. Janich, M. Wilsch-Bräuninger, C.A. Fargeas, A.M. Marzesco, G. Ehninger, C. Thiede, W.B. Huttner, D. Corbeil (2007) Prominin-2 is a cholesterol-binding protein associated with apical and basolateral plasmalemmal protrusions in polarized epithelial cells and released into the urine. Cell Tiss Res 328: 31-47.
27. Freund, D., J. Oswald, S. Feldmann, G. Ehninger, D. Corbeil, M. Bornhäuser (2006a) Comparative analysis of proliferative potential and clonogenicity of MACS-immunomagnetic isolated CD34+ and CD133+ blood stem cells derived from a single donor. Cell Prolif 39: 325-332.
28. Freund, D., N. Bauer, S. Boxberger, S. Feldmann, U. Streller, G. Ehninger, C. Werner, M. Bornhäuser, J. Oswald, D. Corbeil (2006b) Polarization of human hematopoietic progenitors during contact with multipotent mesenchymal stromal cells - effects on proliferation and clonogenicity. Stem Cells Dev 15: 815-829.
29. Frimberger, A.E., C.I. McAuliffe, K.A. Werme, R.A. Tuft, K.E. Fogarty, B.O. Benoit, M.S. Dooner, P.J. Quesenberry (2001) The fleet feet of haematopoietic stem cells: rapid motility, interaction and proteopodia. Br J Haematol 112: 644-654.
30. Fruehauf, S., K. Srbic, R. Seggewiss, J. Topaly, A.D. Ho (2002) Functional characterization of podia formation in normal and malignant hematopoietic cells. J Leukoc Biol 71: 425-432.
31. - hematopoietic stem cells using cell surface markers AC133 and CD7. Blood 95: 2813-2820.
32. Gehling, U.M., S. Ergun, U. Schumacher, C. Wagener, K. Pantel, M. Otte, G. Schuch, P. Schafhausen, T. Mende, N. Kilic, K. Kluge, B. Schafer, D.K. Hossfeld, W. Fiedler (2000) In vitro differentiation of endothelial cells from AC133-positive progenitor cells. Blood 95: 3106-3112.
33. Gerdes, H.H., N.V. Bukoreshtliev, J.F.V. Barroso (2007) Tunneling nanotubes: a new route for the exchange of components between animal cells. FEBS Lett 581: 2194-2201.
34. Ghiaur, G., A. Lee, J. Bailey, J.A. Cancelas, Y. Zheng, D.A. Williams (2006) Inhibition of RhoA GTPase activity enhances hematopoietic stem and progenitor cell proliferation and engraftment. Blood 108: 2087-2094.
35. Giebel, B., D. Corbeil, J. Beckmann, J. Höhn, D. Freund, K. Giesen, J. Fischer, G. Kögler, P. Wernet (2004) Segregation of lipid raft markers including CD133 in polarized human hematopoietic stem and progenitor cells. Blood 104: 2332-2338.
36. Gillette, J.M., F. Pruefer, J. Zhou, J. Lippincott-Schwartz (2006) Live cell imaging of interactions between hematopoietic progenitor cells and osteoblastic cells (abstract 2106). American Society for Cell Biology Meeting, San Diego.
37. Gómez-Moutón, C., J. Abad, E. Mira, R. Lacalle, E. Gallardo, S. Jíménez-Baranda, I. Illa, A. Bernad, S. Mañes, C. Martínez-A (2001) Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization. Proc Natl Acad Sci USA 98: 9642-9647.
38. Gordon, P.R., T. Leimig, A. Babarin-Dorner, J. Houston, M. Holladay, I. Mueller, T. Geiger, R. Handgretinger (2003) Large-scale isolation of CD133+ progenitor cells from G-CSF mobilized peripheral blood stem cells. Bone Marrow Transpl 31: 17-22.
39. Grskovic, B., K. Ruzicka, A. Karimi, D. Qujeq, M.M. Müller (2004) Cell cycle analysis of the CD133+ and CD133- cells isolated from umbilical cord blood. Clin Chim Acta 343: 173-178.
40. Hardy, C.L. (1995) The homing of hematopoietic stem cells to the bone marrow. Am J Med Sci 309: 260-266.
41. Janich, P., D. Corbeil (2007) GM1 and GM3 gangliosides highlight distinct lipid microdomains within the apical domain of epithelial cells. FEBS Lett 581: 1783-1787.
42. Jászai, J., C.A. Fargeas, M. Florek, W.B. Huttner, D. Corbeil (2007a) Focus on Molecules: Prominin-1 (CD133). Exp Eye Res 85: 585-586.
43. Jászai, J., P. Janich, L.M. Farkas, C.A. Fargeas, W.B. Huttner, D. Corbeil (2007b) Differential expression of prominin-1 (CD133) and prominin-2 in major cephalic exocrine glands of adult mice. Histochem Cell Biol 128: 409-419.
44. - early progenitors cultured over human MSCs as a feeder layer. Stem Cells 20: 573-582.
45. Kania, G., D. Corbeil, J. Fuchs, K.V. Tarasov, P. Blyszczuk, W.B. Huttner, K.R. Boheler, A.M. Wobus (2005) The somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cell-derived progenitors. Stem Cells 23: 791-804.
46. Kiel, M.J., S.J. Morrison (2006) Maintaining hematopoietic stem cells in the vascular niche. Immunity 25: 862-864.
47. Koehl, U., S. Zimmermann, R. Esser, J. Sorensen, H.P. Gruttner, M. Duchscherer, E. Seifried, T. Klingebiel, D. Schwabe (2002) Autologous transplantation of CD133 selected hematopoietic progenitor cells in a pediatric patient with relapsed leukemia. Bone Marrow Transplant 29: 927-930.
48. Konakahara, S., K. Ohashi, K. Mizuno, K. Itoh, T. Tsuji (2004) CD29 integrin- and LIMK1/cofilin-mediated actin reorganization regulates the migration of haematopoietic progenitor cells underneath bone marrow stromal cells. Genes Cells 9: 354-358.
49. Kosodo, Y., K. Röper, W. Haubensak, A.-M. Marzesco, D. Corbeil, W.B. Huttner (2004) Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells. EMBO J 23: 2314-2324.
50. Kratz-Albers, K., M. Zuhlsdorp, R. Leo, W.L. Berdel, T. Buchner, H. Serve (1998) Expression of a AC133, a novel stem cell marker, on human leukemic blasts lacking CD34-antigen and on a human CD34+ leukemic line: MUTZ-2. Blood 92: 4485-4487.
51. Krause, D.S., M.J. Fackler, C.I. Civin, W.S. May (1996) CD34: structure, biology, and clinical utility. Blood 87: 1-13.
52. Kuci, S., J.T. Wessels, H.J. Buhring, K. Schilbach, M. Schumm, G. Seitz, J. Loffler, P. Bader, P.G. Schlegel, D. Niethammer, R. Handgretinger (2003) Identification of a novel class of human adherent CD34- stem cells that give rise to SCID-repopulating cells. Blood 101: 869-876.
53. Lang, P., P. Bader, M. Schumm, T. Feuchtinger, H. Einsele, M. Fuhrer, C. Weinstock, R. Handgretinger, S. Kuci, D. Martin, D. Niethammer, J. Greil (2004) Transplantation of a combination of CD133+ and CD34+ selected progenitor cells from alternative donors. Br J Haematol 124: 72-79.
54. null mice. Leukemia 16: 1992-2003.
55. Lardon, J., D. Corbeil, W.B. Huttner, Z. Ling, L. Bouwens (2007) Stem cell marker prominin 1/AC133 is expressed in duct cells of the adult human pancreas. Pancreas, in press.
56. Lee, A., J.D. Kessler, T.A. Read, C. Kaiser, D. Corbeil, W.B. Huttner, J.E. Johnson, R.J. Wechsler-Reya (2005) Isolation of neural stem cells from postnatal cerebellum. Nat Neurosci 8: 723-729.
57. Li, Z., L. Li (2006) Understanding hematopoietic stem-cell microenvironments. Trends Biochem Sci 31: 589-595.
58. Luster, A.D., R. Alon, U.H. von Adrian (2005) Immune cell migration in inflammation: present and future therapeutic targets. Nat Immunol 6: 1182-1190.
59. Majumdar M.K., M.A. Thiede, S.E. Haynesworth, S.P. Bruder, S.L. Gerson (2000) Human marrow-derived mesenchymal stem cells (MSCs) express hematopoietic cytokines and support long-term hematopoiesis when differentiated toward stromal and osteogenic lineages. J Hematother Stem Cell Res 9: 841-848.
60. Marzesco, A.-M., P. Janich, M. Wilsch-Bräuninger, V. Dubreuil, K. Langenfeld, D. Corbeil, W.B. Huttner (2005) Release of extracellular membrane particles carrying the stem cell marker prominin-1 (CD133) from neural progenitors and other epithelial cells. J Cell Sci 118: 2849-2858.
61. Matsumoto, K., K. Yasui, N. Yamashita, Y. Horie, T. Yamada, Y. Tani, H. Shibata, T. Nakano (2000) In vitro proliferation potential of AC133 positive cells in peripheral blood. Stem Cells 18: 196-203.
62. Maw, M.A., D. Corbeil, J. Koch, A. Hellwig, J.C. Wilson-Wheeler, R.J. Bridges, G. Kumaramanickavel, S. John, D. Nancarrow, K. Röper, A. Weigmann, W.B. Huttner, M.J. Denton (2000) A frameshift mutation in prominin (mouse)-like 1 causes human retinal degeneration. Hum Mol Genet 9: 27-34.
63. Miraglia, S., W. Godfrey, A.H. Yin, K. Atkins, R. Warnke, J.T. Holden, R.A. Bray, E.K. Waller, D.W. Buck (1997) A novel five-transmembrane hematopoietic stem cell antigen: isolation, characterization, and molecular cloning. Blood 90: 5013-5021.
64. Nguyen, D.H., J.E. Hildreth (2000) Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts. J Virol 74: 3264-3272.
65. O'Brien, C.A., A. Pollett, S. Gallinger, J.E. Dick (2007) A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445: 106-110.
66. Padovan, C.S., K. Jahn, T. Birnbaum, P. Reich, P. Sostak, M. Strupp, A. Straube (2003) Expression of neuronal markers in differentiated marrow stromal cells and CD133+ stem-like cells. Cell Transpl 12: 839-848.
67. Papayannopoulou, T., C. Craddock, B. Nakamoto, G.V. Priestly, N.S. Wolf (1995) The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hematopoietic progenitors between bone marrow and spleen. Proc Natl Acad Sci USA 92: 9647-9651.
68. Pike, L.J. (2004) Lipid rafts: heterogeneity on the high seas. Biochem J 378: 281-292.
69. Pike, L.J. (2006) Rafts defined: a report on the Keystone Symposium on Lipid Rafts and Cell Function. J Lipid Res 47: 1597-1598.
70. + cells. Br J Haematol 115: 186-194.
71. Ricci-Vitiani, L., D.G. Lombardi, E. Pilozzi, M. Biffoni, M. Todaro, C. Peschle, R. De Maria (2007) Identification and expansion of human colon-cancer-initiating cells. Nature 445: 111-115.
72. Richardson, G.D., C.N. Robson, S.H. Lang, D.E. Neal, N.J. Maitland, A.T. Collins (2004) CD133, a novel marker for human prostatic epithelial stem cells. J Cell Sci 117: 3539-3545.
73. Röper, K., D. Corbeil, W.B. Huttner (2000) Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane. Nat Cell Biol 2: 582-592.
74. Rustom, A., R. Saffrich, I. Markovic, P. Walther, H.H. Gerdes (2004) Nanotubular highways for intercellular organelle transport. Science 303: 1007-1010.
75. Sanchez-Madrid, F., M.A. del Pozo (1999) Leukocyte polarization in cell migration and immune interactions. EMBO J 18: 501-511.
76. Simons, K., D. Toomre (2000) Lipid rafts and signal transduction. Nat Rev Mol Cell Biol 1: 31-39.
77. Singh, S.K., C. Hawkins, I.D. Clarke, J.A. Squire, J. Bayani, T. Hide, R.M. Henkelman, M.D. Cusimano, P.B. Dirks (2004) Identification of human brain tumour initiating cells. Nature 432: 396-401.
78. + stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle. J Clin Invest 114: 182-195.
79. Uchida, N., D.W. Buck, D. He, M.J. Reitsma, M. Masek, T.V. Phan, A.S. Tsukamoto, F.H. Gage, I.L. Weissman (2000) Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci USA 97: 14720-14725.
80. Van Overstraeten-Schlogel, N., Y. Beguin, A. Gothot (2006) Role of stromal-derived factor-1 in the hematopoietic-supporting activity of human mesenchymal stem cells. Eur J Haematol 76: 488-493.
81. Varnum-Finney, B., L. Wu, M. Yu, C. Brashem-Stein, S. Staats, D. Flowers, J.D. Griffin, I.D. Bernstein (2000) Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling. J Cell Sci 113: 4313-4318.
82. Wagner, W., R. Saffrich, U. Wirkner, V. Eckstein, J. Blake, A. Ansorge, C. Schwager, F. Wein, K. Miesala, W. Ansorge, A.D. Ho (2005) Hematopoietic progenitor cells and cellular microenvironment: behavioral and molecular changes upon interaction. Stem Cells 23: 1180-1191.
83. Wagner, W., F. Wein, C. Roderburg, R. Saffrich, A. Faber, U. Krause, M. Schubert, V. Benes, V. Eckstein, H. Maul, A.D. Ho (2007) Adhesion of hematopoietic progenitor cells to human mesenchymal stem cells as a model for cell-cell interaction. Exp Hematol 35: 314-325.
84. Weigmann, A., D. Corbeil, A. Hellwig, W.B. Huttner (1997) Prominin, a novel microvillispecific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells. Proc Natl Acad Sci USA 94: 12425-12430.
85. Wilson, A., A. Trumpp (2006) Bone-marrow haematopoietic-stem-cell niches. Nat Rev Immunol 6: 93-106.
86. Wright, D.E., A.J. Wagers, A.P. Gulati, F.L. Johnson, I.L. Weissman (2001) Physiological migration of hematopoietic stem and progenitor cells. Science 294: 1933-1936.
87. Yang, L., L. Wang, H. Geiger, J.A. Cancelas, J. Mo, Y. Zheng (2007) Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow. Proc Natl Acad Sci USA 104: 5091-5096.
88. Yin, A.H., S. Miraglia, E.D. Zanjani, G. Almeida-Porada, M. Ogawa, A.G. Leary, J. Olweus, J. Kearney, D.W. Buck (1997) AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 90: 5002-5012.
89. Yonemura, S., A. Nagafuchi, N. Sato, S. Tsukita (1993) Concentration of an integral membrane protein, CD43 (leukosialin, sialophorin), in the cleavage furrow through the interaction of its cytoplasmic domain with actin-based cytoskeletons. J Cell Biol 120: 437-449.
90. Yu, Y., A. Flint, E.L. Dvorin, J. Bischoff (2002) AC133-2, a novel isoform of human AC133 stem cell antigen. J Biol Chem 277: 20711-20716.
91. Zhang, Q., F. Zulfiqar, X. Xiao, S.A. Riazuddin. Z. Ahmad, R. Caruso, I. Macdonald, P. Sieving, S. Riazuddin, J.F. Hejtmancik (2007) Severe retinitis pigmentosa mapped to 4p15 and associated with a novel mutation in the PROM1 gene. Hum Genet 122: 293-299.