Growth-factor receptor-bound protein-2 (Grb2) signaling in B cells controls lymphoid follicle organization and germinal center reaction

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 19, 2011, Pages 7926-7931

  Jang, Ihn Kyung ^a,d   Cronshaw, Darran G ^b   Xie, Luo Kun ^b   Fang, Guoqiang ^b   Zhang, Jinping ^a,e   Oh, Hyunju ^a   Fu, Yang Xin ^c   Gu, Hua ^a   Zou, Yongrui ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e SOOCHOW UNIVERSITY   (China)

Author keywords

B cell signaling and activation; Chemokine signaling; Follicular dendritic cell development; Germinal center development; Regulation of lymphotoxin expression

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD40 LIGAND; CXCL13 CHEMOKINE; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; IMMUNOGLOBULIN; LYMPHOTOXIN BETA;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL MATURATION; CELL MUTANT; CHEMOTAXIS; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GERMINAL CENTER; IMMUNIZATION; IMMUNOFLUORESCENCE; IN VITRO STUDY; LYMPH FOLLICLE; MOUSE; MOUSE MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPLEEN; UPREGULATION; WESTERN BLOTTING;

ANIMALS; B-LYMPHOCYTES; CD40 LIGAND; CELL DIFFERENTIATION; CHEMOKINE CXCL13; GENE EXPRESSION; GERMINAL CENTER; GRB2 ADAPTOR PROTEIN; LYMPHOCYTE ACTIVATION; LYMPHOTOXIN-BETA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, CXCR5; SIGNAL TRANSDUCTION; SPLEEN;

MUS;

EID: 79956348707     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1016451108     Document Type: Article

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