Recruitment of the cytoplasmic adaptor Grb2 to surface IgG and IgE provides antigen receptor-intrinsic costimulation to class-switched B cells

Nature Immunology

Volumn 10, Issue 9, 2009, Pages 1018-1025

  Engels, Niklas ^a   König, Lars Morten ^a   Heemann, Christina ^a   Lutz, Johannes ^a   Tsubata, Takeshi ^b   Griep, Sebastian ^a   Schrader, Verena ^a   Wienands, Jürgen ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CALCIUM ION; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN HEAVY CHAIN ALPHA; IMMUNOGLOBULIN HEAVY CHAIN BETA; IMMUNOGLOBULIN M; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; CALCIUM CELL LEVEL; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; GENE SWITCHING; HUMAN; HUMAN CELL; IMMUNOGLOBULIN HEAVY CHAIN GENE; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; B-LYMPHOCYTES; CALCIUM; CELL LINE, TUMOR; CYTOPLASM; GRB2 ADAPTOR PROTEIN; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PROTEIN TRANSPORT; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION; TYROSINE;

EID: 69049105207     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1764     Document Type: Article

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