-
1
-
-
55849095891
-
Evidence that cytokines play a role in rheumatoid arthritis
-
Brennan, F. M., and I. B. McInnes. 2008. Evidence that cytokines play a role in rheumatoid arthritis. J. Clin. Invest. 118: 3537-3545.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3537-3545
-
-
Brennan, F.M.1
McInnes, I.B.2
-
2
-
-
0026717674
-
The pathophysiology of tumor necrosis factors
-
Vassalli, P. 1992. The pathophysiology of tumor necrosis factors. Annu. Rev. Immunol. 10: 411-452.
-
(1992)
Annu. Rev. Immunol.
, vol.10
, pp. 411-452
-
-
Vassalli, P.1
-
4
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
Hayden, M. S., and S. Ghosh. 2008. Shared principles in NF-kappaB signaling. Cell 132: 344-362.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
5
-
-
67650724069
-
Regulation and function of NFkappaB transcription factors in the immune system
-
Vallabhapurapu, S., and M. Karin. 2009. Regulation and function of NFkappaB transcription factors in the immune system. Annu. Rev. Immunol. 27: 693-733.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
6
-
-
0033537866
-
Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation
-
Sakurai, H., H. Miyoshi, W. Toriumi, and T. Sugita. 1999. Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation. J. Biol. Chem. 274: 10641-10648.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10641-10648
-
-
Sakurai, H.1
Miyoshi, H.2
Toriumi, W.3
Sugita, T.4
-
7
-
-
27744577296
-
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
-
DOI 10.1101/gad.1360605
-
Shim, J. H., C. Xiao, A. E. Paschal, S. T. Bailey, P. Rao, M. S. Hayden, K. Y. Lee, C. Bussey, M. Steckel, N. Tanaka, et al. 2005. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo. Genes Dev. 19: 2668-2681. (Pubitemid 41627934)
-
(2005)
Genes and Development
, vol.19
, Issue.22
, pp. 2668-2681
-
-
Shim, J.-H.1
Xiao, C.2
Paschal, A.E.3
Bailey, S.T.4
Rao, P.5
Hayden, M.S.6
Lee, K.-Y.7
Bussey, C.8
Steckel, M.9
Tanaka, N.10
Yamada, G.11
Akira, S.12
Matsumoto, K.13
Ghosh, S.14
-
8
-
-
15844431960
-
A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3
-
Moriguchi, T., N. Kuroyanagi, K. Yamaguchi, Y. Gotoh, K. Irie, T. Kano, K. Shirakabe, Y. Muro, H. Shibuya, K. Matsumoto, et al. 1996. A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3. J. Biol. Chem. 271: 13675-13679.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13675-13679
-
-
Moriguchi, T.1
Kuroyanagi, N.2
Yamaguchi, K.3
Gotoh, Y.4
Irie, K.5
Kano, T.6
Shirakabe, K.7
Muro, Y.8
Shibuya, H.9
Matsumoto, K.10
-
9
-
-
0030968634
-
TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase
-
Shirakabe, K., K. Yamaguchi, H. Shibuya, K. Irie, S. Matsuda, T. Moriguchi, Y. Gotoh, K. Matsumoto, and E. Nishida. 1997. TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase. J. Biol. Chem. 272: 8141-8144.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8141-8144
-
-
Shirakabe, K.1
Yamaguchi, K.2
Shibuya, H.3
Irie, K.4
Matsuda, S.5
Moriguchi, T.6
Gotoh, Y.7
Matsumoto, K.8
Nishida, E.9
-
10
-
-
0027944227
-
BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2
-
Tamagnone, L., I. Lahtinen, T. Mustonen, K. Virtaneva, F. Francis, F. Muscatelli, R. Alitalo, C. I. Smith, C. Larsson, and K. Alitalo. 1994. BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2. Oncogene 9: 3683-3688.
-
(1994)
Oncogene
, vol.9
, pp. 3683-3688
-
-
Tamagnone, L.1
Lahtinen, I.2
Mustonen, T.3
Virtaneva, K.4
Francis, F.5
Muscatelli, F.6
Alitalo, R.7
Smith, C.I.8
Larsson, C.9
Alitalo, K.10
-
11
-
-
0033190523
-
Tec family of protein-tyrosine kinases: An overview of their structure and function
-
DOI 10.1016/S1359-6101(99)00019-2, PII S1359610199000192
-
Mano, H. 1999. Tec family of protein-tyrosine kinases: an overview of their structure and function. Cytokine Growth Factor Rev. 10: 267-280. (Pubitemid 30041404)
-
(1999)
Cytokine and Growth Factor Reviews
, vol.10
, Issue.3-4
, pp. 267-280
-
-
Mano, H.1
-
12
-
-
0030662106
-
Predominant expression of murine Bmx tyrosine kinase in the granulo-monocytic lineage
-
Weil, D., M. A. Power, S. I. Smith, and C. L. Li. 1997. Predominant expression of murine Bmx tyrosine kinase in the granulo-monocytic lineage. Blood 90: 4332-4340.
-
(1997)
Blood
, vol.90
, pp. 4332-4340
-
-
Weil, D.1
Power, M.A.2
Smith, S.I.3
Li, C.L.4
-
13
-
-
0029791422
-
BMX tyrosine kinase gene is expressed in granulocytes and myeloid leukaemias
-
Kaukonen, J., I. Lahtinen, S. Laine, K. Alitalo, and A. Palotie. 1996. BMX tyrosine kinase gene is expressed in granulocytes and myeloid leukaemias. Br. J. Haematol. 94: 455-460.
-
(1996)
Br. J. Haematol.
, vol.94
, pp. 455-460
-
-
Kaukonen, J.1
Lahtinen, I.2
Laine, S.3
Alitalo, K.4
Palotie, A.5
-
14
-
-
0030756590
-
Bmx tyrosine kinase is specifically expressed in the endocardium and the endothelium of large arteries
-
Ekman, N., A. Lymboussaki, I. Västrik, K. Sarvas, A. Kaipainen, and K. Alitalo. 1997. Bmx tyrosine kinase is specifically expressed in the endocardium and the endothelium of large arteries. Circulation 96: 1729-1732. (Pubitemid 27400725)
-
(1997)
Circulation
, vol.96
, Issue.6
, pp. 1729-1732
-
-
Ekman, N.1
Lymboussaki, A.2
Vastrik, I.3
Sarvas, K.4
Kaipainen, A.5
Alitalo, K.6
-
15
-
-
41549110303
-
Expression of Etk/Bmx tyrosine kinase in intrahepatic cholangiocarcinoma
-
Guo, L., Y. Guo, and S. Xiao. 2008. Expression of Etk/Bmx tyrosine kinase in intrahepatic cholangiocarcinoma. J. Surg. Oncol. 97: 428-432.
-
(2008)
J. Surg. Oncol.
, vol.97
, pp. 428-432
-
-
Guo, L.1
Guo, Y.2
Xiao, S.3
-
16
-
-
39049115413
-
Expression of tyrosine kinase Etk/Bmx and its relationship with AP-1- and NF-kappaB-associated proteins in hepatocellular carcinoma
-
DOI 10.1159/000113491
-
Guo, L., Y. Guo, and S. Xiao. 2007. Expression of tyrosine kinase Etk/Bmx and its relationship with AP-1- and NF-kappaB-associated proteins in hepatocellular carcinoma. Oncology 72: 410-416. (Pubitemid 351238157)
-
(2007)
Oncology
, vol.72
, Issue.5-6
, pp. 410-416
-
-
Guo, L.1
Guo, Y.2
Xiao, S.3
-
17
-
-
33748071774
-
Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse
-
DOI 10.1158/0008-5472.CAN-06-1364
-
Dai, B., O. Kim, Y. Xie, Z. Guo, K. Xu, B. Wang, X. Kong, J. Melamed, H. Chen, C. J. Bieberich, et al. 2006. Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse. Cancer Res. 66: 8058-8064. (Pubitemid 44299171)
-
(2006)
Cancer Research
, vol.66
, Issue.16
, pp. 8058-8064
-
-
Dai, B.1
Kim, O.2
Xie, Y.3
Guo, Z.4
Xu, K.5
Wang, B.6
Kong, X.7
Melamed, J.8
Chen, H.9
Bieberich, C.J.10
Borowsky, A.D.11
Kung, H.-J.12
Wei, G.13
Ostrowski, M.C.14
Brodie, A.15
Qiu, Y.16
-
18
-
-
23144450821
-
A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling
-
Côté, J. F., A. B. Motoyama, J. A. Bush, and K. Vuori. 2005. A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling. Nat. Cell Biol. 7: 797-807.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 797-807
-
-
Côté, J.F.1
Motoyama, A.B.2
Bush, J.A.3
Vuori, K.4
-
19
-
-
0031029781
-
Regulatory intramolecular association in a tyrosine kinase of the Tec family
-
Andreotti, A. H., S. C. Bunnell, S. Feng, L. J. Berg, and S. L. Schreiber. 1997. Regulatory intramolecular association in a tyrosine kinase of the Tec family. Nature 385: 93-97.
-
(1997)
Nature
, vol.385
, pp. 93-97
-
-
Andreotti, A.H.1
Bunnell, S.C.2
Feng, S.3
Berg, L.J.4
Schreiber, S.L.5
-
20
-
-
0036135326
-
Competing modes of self-association in the regulatory domains of Bruton's tyrosine kinase: Intramolecular contact versus asymmetric homodimerization
-
Laederach, A., K. W. Cradic, K. N. Brazin, J. Zamoon, D. B. Fulton, X. Y. Huang, and A. H. Andreotti. 2002. Competing modes of self-association in the regulatory domains of Bruton's tyrosine kinase: intramolecular contact versus asymmetric homodimerization. Protein Sci. 11: 36-45.
-
(2002)
Protein Sci.
, vol.11
, pp. 36-45
-
-
Laederach, A.1
Cradic, K.W.2
Brazin, K.N.3
Zamoon, J.4
Fulton, D.B.5
Huang, X.Y.6
Andreotti, A.H.7
-
21
-
-
0041816053
-
p130Cas Couples the tyrosine kinase Bmx/Etk with regulation of the actin cytoskeleton and cell migration
-
Abassi, Y. A., M. Rehn, N. Ekman, K. Alitalo, and K. Vuori. 2003. p130Cas Couples the tyrosine kinase Bmx/Etk with regulation of the actin cytoskeleton and cell migration. J. Biol. Chem. 278: 35636-35643.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 35636-35643
-
-
Abassi, Y.A.1
Rehn, M.2
Ekman, N.3
Alitalo, K.4
Vuori, K.5
-
22
-
-
0035003136
-
Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain
-
Chen, R., O. Kim, M. Li, X. Xiong, J. L. Guan, H. J. Kung, H. Chen, Y. Shimizu, and Y. Qiu. 2001. Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain. Nat. Cell Biol. 3: 439-444.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 439-444
-
-
Chen, R.1
Kim, O.2
Li, M.3
Xiong, X.4
Guan, J.L.5
Kung, H.J.6
Chen, H.7
Shimizu, Y.8
Qiu, Y.9
-
23
-
-
0347065353
-
Etk/Bmx transactivates vascular endothelial growth factor 2 and recruits phosphatidylinositol 3-kinase to mediate the tumor necrosis factor-induced angiogenic pathway
-
Zhang, R., Y. Xu, N. Ekman, Z. Wu, J. Wu, K. Alitalo, and W. Min. 2003. Etk/Bmx transactivates vascular endothelial growth factor 2 and recruits phosphatidylinositol 3-kinase to mediate the tumor necrosis factor-induced angiogenic pathway. J. Biol. Chem. 278: 51267-51276.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51267-51276
-
-
Zhang, R.1
Xu, Y.2
Ekman, N.3
Wu, Z.4
Wu, J.5
Alitalo, K.6
Min, W.7
-
24
-
-
0034954684
-
Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium
-
Rajantie, I., N. Ekman, K. Iljin, E. Arighi, Y. Gunji, J. Kaukonen, A. Palotie, M. Dewerchin, P. Carmeliet, and K. Alitalo. 2001. Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium. Mol. Cell. Biol. 21: 4647-4655.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4647-4655
-
-
Rajantie, I.1
Ekman, N.2
Iljin, K.3
Arighi, E.4
Gunji, Y.5
Kaukonen, J.6
Palotie, A.7
Dewerchin, M.8
Carmeliet, P.9
Alitalo, K.10
-
25
-
-
33748292990
-
Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis
-
He, Y., Y. Luo, S. Tang, I. Rajantie, P. Salven, M. Heil, R. Zhang, D. Luo, X. Li, H. Chi, et al. 2006. Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis. J. Clin. Invest. 116: 2344-2355.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2344-2355
-
-
He, Y.1
Luo, Y.2
Tang, S.3
Rajantie, I.4
Salven, P.5
Heil, M.6
Zhang, R.7
Luo, D.8
Li, X.9
Chi, H.10
-
26
-
-
78650383216
-
Functional analyses of the bone marrow kinase in the X chromosome in vascular endothelial growth factor-induced lymphangiogenesis
-
Jones, D., Z. Xu, H. Zhang, Y. He, M. S. Kluger, H. Chen, and W. Min. 2010. Functional analyses of the bone marrow kinase in the X chromosome in vascular endothelial growth factor-induced lymphangiogenesis. Arterioscler. Thromb. Vasc. Biol. 30: 2553-2561.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 2553-2561
-
-
Jones, D.1
Xu, Z.2
Zhang, H.3
He, Y.4
Kluger, M.S.5
Chen, H.6
Min, W.7
-
27
-
-
58149385416
-
Loss of Bmx nonreceptor tyrosine kinase prevents pressure overload-induced cardiac hypertrophy
-
Mitchell-Jordan, S. A., T. Holopainen, S. Ren, S. Wang, S. Warburton, M. J. Zhang, K. Alitalo, Y. Wang, and T. M. Vondriska. 2008. Loss of Bmx nonreceptor tyrosine kinase prevents pressure overload-induced cardiac hypertrophy. Circ. Res. 103: 1359-1362.
-
(2008)
Circ. Res.
, vol.103
, pp. 1359-1362
-
-
Mitchell-Jordan, S.A.1
Holopainen, T.2
Ren, S.3
Wang, S.4
Warburton, S.5
Zhang, M.J.6
Alitalo, K.7
Wang, Y.8
Vondriska, T.M.9
-
28
-
-
78149281188
-
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation
-
Bry, M., R. Kivelä, T. Holopainen, A. Anisimov, T. Tammela, J. Soronen, J. Silvola, A. Saraste, M. Jeltsch, P. Korpisalo, et al. 2010. Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation. Circulation 122: 1725-1733.
-
(2010)
Circulation
, vol.122
, pp. 1725-1733
-
-
Bry, M.1
Kivelä, R.2
Holopainen, T.3
Anisimov, A.4
Tammela, T.5
Soronen, J.6
Silvola, J.7
Saraste, A.8
Jeltsch, M.9
Korpisalo, P.10
-
29
-
-
43049096082
-
Bmx regulates LPS-induced IL-6 and VEGF production via mRNA stability in rheumatoid synovial fibroblasts
-
Palmer, C. D., B. E. Mutch, T. H. Page, N. J. Horwood, and B. M. Foxwell. 2008. Bmx regulates LPS-induced IL-6 and VEGF production via mRNA stability in rheumatoid synovial fibroblasts. Biochem. Biophys. Res. Commun. 370: 599-602.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.370
, pp. 599-602
-
-
Palmer, C.D.1
Mutch, B.E.2
Page, T.H.3
Horwood, N.J.4
Foxwell, B.M.5
-
30
-
-
41349109980
-
Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkappB activity
-
Palmer, C. D., B. E. Mutch, S. Workman, J. P. McDaid, N. J. Horwood, and B. M. Foxwell. 2008. Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkappB activity. Blood 111: 1781-1788.
-
(2008)
Blood
, vol.111
, pp. 1781-1788
-
-
Palmer, C.D.1
Mutch, B.E.2
Workman, S.3
McDaid, J.P.4
Horwood, N.J.5
Foxwell, B.M.6
-
31
-
-
43049140184
-
Etk/BMX, a Btk family tyrosine kinase, and Mal contribute to the cross-talk between MyD88 and FAK pathways
-
Semaan, N., G. Alsaleh, J. E. Gottenberg, D. Wachsmann, and J. Sibilia. 2008. Etk/BMX, a Btk family tyrosine kinase, and Mal contribute to the cross-talk between MyD88 and FAK pathways. J. Immunol. 180: 3485-3491.
-
(2008)
J. Immunol.
, vol.180
, pp. 3485-3491
-
-
Semaan, N.1
Alsaleh, G.2
Gottenberg, J.E.3
Wachsmann, D.4
Sibilia, J.5
-
32
-
-
4344568204
-
Bmx tyrosine kinase transgene induces skin hyperplasia, inflammatory angiogenesis, and accelerated wound healing
-
Paavonen, K., N. Ekman, M. Wirzenius, I. Rajantie, M. Poutanen, and K. Alitalo. 2004. Bmx tyrosine kinase transgene induces skin hyperplasia, inflammatory angiogenesis, and accelerated wound healing. Mol. Biol. Cell 15: 4226-4233.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 4226-4233
-
-
Paavonen, K.1
Ekman, N.2
Wirzenius, M.3
Rajantie, I.4
Poutanen, M.5
Alitalo, K.6
-
33
-
-
23444437819
-
Design of a genome-wide siRNA library using an artificial neural network
-
Huesken, D., J. Lange, C. Mickanin, J. Weiler, F. Asselbergs, J. Warner, B. Meloon, S. Engel, A. Rosenberg, D. Cohen, et al. 2005. Design of a genome-wide siRNA library using an artificial neural network. Nat. Biotechnol. 23: 995-1001.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 995-1001
-
-
Huesken, D.1
Lange, J.2
Mickanin, C.3
Weiler, J.4
Asselbergs, F.5
Warner, J.6
Meloon, B.7
Engel, S.8
Rosenberg, A.9
Cohen, D.10
-
34
-
-
33749537857
-
Genome-wide functional analysis of human cell-cycle regulators
-
Mukherji, M., R. Bell, L. Supekova, Y. Wang, A. P. Orth, S. Batalov, L. Miraglia, D. Huesken, J. Lange, C. Martin, et al. 2006. Genome-wide functional analysis of human cell-cycle regulators. Proc. Natl. Acad. Sci. USA 103: 14819-14824.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 14819-14824
-
-
Mukherji, M.1
Bell, R.2
Supekova, L.3
Wang, Y.4
Orth, A.P.5
Batalov, S.6
Miraglia, L.7
Huesken, D.8
Lange, J.9
Martin, C.10
-
35
-
-
43549122365
-
Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells
-
Rines, D. R., M. A. Gomez-Ferreria, Y. Zhou, P. DeJesus, S. Grob, S. Batalov, M. Labow, D. Huesken, C. Mickanin, J. Hall, et al. 2008. Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells. Genome Biol. 9: R44.
-
(2008)
Genome Biol.
, vol.9
-
-
Rines, D.R.1
Gomez-Ferreria, M.A.2
Zhou, Y.3
DeJesus, P.4
Grob, S.5
Batalov, S.6
Labow, M.7
Huesken, D.8
Mickanin, C.9
Hall, J.10
-
36
-
-
0030606310
-
Organ-specific disease provoked by systemic autoimmunity
-
DOI 10.1016/S0092-8674(00)81989-3
-
Kouskoff, V., A. S. Korganow, V. Duchatelle, C. Degott, C. Benoist, and D. Mathis. 1996. Organ-specific disease provoked by systemic autoimmunity. Cell 87: 811-822. (Pubitemid 26404281)
-
(1996)
Cell
, vol.87
, Issue.5
, pp. 811-822
-
-
Kouskoff, V.1
Korganow, A.-S.2
Duchatelle, V.3
Degott, C.4
Benoist, C.5
Mathis, D.6
-
38
-
-
0037422858
-
TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway
-
Takaesu, G., R. M. Surabhi, K. J. Park, J. Ninomiya-Tsuji, K. Matsumoto, and R. B. Gaynor. 2003. TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway. J. Mol. Biol. 326: 105-115.
-
(2003)
J. Mol. Biol.
, vol.326
, pp. 105-115
-
-
Takaesu, G.1
Surabhi, R.M.2
Park, K.J.3
Ninomiya-Tsuji, J.4
Matsumoto, K.5
Gaynor, R.B.6
-
39
-
-
30044449755
-
TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation
-
Blonska, M., P. B. Shambharkar, M. Kobayashi, D. Y. Zhang, H. Sakurai, B. Su, and X. Lin. 2005. TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation. J. Biol. Chem. 280: 43056-43063.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 43056-43063
-
-
Blonska, M.1
Shambharkar, P.B.2
Kobayashi, M.3
Zhang, D.Y.4
Sakurai, H.5
Su, B.6
Lin, X.7
-
40
-
-
0029949257
-
TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
-
Hsu, H. L., J. N. Huang, H. B. Shu, V. Baichwal, and D. V. Goeddel. 1996. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 4: 387-396.
-
(1996)
Immunity
, vol.4
, pp. 387-396
-
-
Hsu, H.L.1
Huang, J.N.2
Shu, H.B.3
Baichwal, V.4
Goeddel, D.V.5
-
41
-
-
4043136609
-
The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2
-
Lee, T. H., J. Shank, N. Cusson, and M. A. Kelliher. 2004. The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2. J. Biol. Chem. 279: 33185-33191.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 33185-33191
-
-
Lee, T.H.1
Shank, J.2
Cusson, N.3
Kelliher, M.A.4
-
42
-
-
0242663910
-
The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinase
-
Lee, T. H., Q. J. Huang, S. Oikemus, J. Shank, J. J. Ventura, N. Cusson, R. R. Vaillancourt, B. Su, R. J. Davis, and M. A. Kelliher. 2003. The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinase. Mol. Cell. Biol. 23: 8377-8385.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8377-8385
-
-
Lee, T.H.1
Huang, Q.J.2
Oikemus, S.3
Shank, J.4
Ventura, J.J.5
Cusson, N.6
Vaillancourt, R.R.7
Su, B.8
Davis, R.J.9
Kelliher, M.A.10
-
43
-
-
0032575591
-
Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting protein associates with a mitogen-activated protein kinase kinase kinase upstream of MKK6 and p38
-
Yuasa, T., S. Ohno, J. H. Kehrl, and J. M. Kyriakis. 1998. Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting protein associates with a mitogen-activated protein kinase kinase kinase upstream of MKK6 and p38. J. Biol. Chem. 273: 22681-22692.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22681-22692
-
-
Yuasa, T.1
Ohno, S.2
Kehrl, J.H.3
Kyriakis, J.M.4
-
44
-
-
0029940355
-
TAB1: An activator of the TAK1 MAPKKK in TGF-beta signal transduction
-
Shibuya, H., K. Yamaguchi, K. Shirakabe, A. Tonegawa, Y. Gotoh, N. Ueno, K. Irie, E. Nishida, and K. Matsumoto. 1996. TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. Science 272: 1179-1182.
-
(1996)
Science
, vol.272
, pp. 1179-1182
-
-
Shibuya, H.1
Yamaguchi, K.2
Shirakabe, K.3
Tonegawa, A.4
Gotoh, Y.5
Ueno, N.6
Irie, K.7
Nishida, E.8
Matsumoto, K.9
-
45
-
-
0023128439
-
DNA sequence encoding the amino-terminal region of the human c-src protein: Implications of sequence divergence among src-type kinase oncogenes
-
Tanaka, A., C. P. Gibbs, R. R. Arthur, S. K. Anderson, H. J. Kung, and D. J. Fujita. 1987. DNA sequence encoding the amino-terminal region of the human c-src protein: implications of sequence divergence among src-type kinase oncogenes. Mol. Cell. Biol. 7: 1978-1983.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 1978-1983
-
-
Tanaka, A.1
Gibbs, C.P.2
Arthur, R.R.3
Anderson, S.K.4
Kung, H.J.5
Fujita, D.J.6
-
46
-
-
0036838086
-
Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: Role in endothelial cell migration and angiogenesis
-
Pan, S., P. An, R. Zhang, X. He, G. Yin, and W. Min. 2002. Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesis. Mol. Cell. Biol. 22: 7512-7523.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7512-7523
-
-
Pan, S.1
An, P.2
Zhang, R.3
He, X.4
Yin, G.5
Min, W.6
-
47
-
-
0028999058
-
Activation of Bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain
-
Li, T. J., S. Tsukada, A. Satterthwaite, M. H. Havlik, H. Park, K. Takatsu, and O. N. Witte. 1995. Activation of Bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain. Immunity 2: 451-460.
-
(1995)
Immunity
, vol.2
, pp. 451-460
-
-
Li, T.J.1
Tsukada, S.2
Satterthwaite, A.3
Havlik, M.H.4
Park, H.5
Takatsu, K.6
Witte, O.N.7
-
48
-
-
0030771737
-
Constitutive membrane association potentiates activation of Bruton tyrosine kinase
-
Li, T. J., D. J. Rawlings, H. Park, R. M. Kato, O. N. Witte, and A. B. Satterthwaite. 1997. Constitutive membrane association potentiates activation of Bruton tyrosine kinase. Oncogene 15: 1375-1383.
-
(1997)
Oncogene
, vol.15
, pp. 1375-1383
-
-
Li, T.J.1
Rawlings, D.J.2
Park, H.3
Kato, R.M.4
Witte, O.N.5
Satterthwaite, A.B.6
-
49
-
-
14244262138
-
Inhibition of RIP2/RIck/CARDIAK activity by pyridinyl imidazole inhibitors of p38 MAPK
-
Argast, G. M., N. Fausto, and J. S. Campbell. 2005. Inhibition of RIP2/RIck/CARDIAK activity by pyridinyl imidazole inhibitors of p38 MAPK. Mol. Cell. Biochem. 268: 129-140.
-
(2005)
Mol. Cell. Biochem.
, vol.268
, pp. 129-140
-
-
Argast, G.M.1
Fausto, N.2
Campbell, J.S.3
-
50
-
-
9144219693
-
An efficient proteomics method to identify the cellular targets of protein kinase inhibitors
-
Godl, K., J. Wissing, A. Kurtenbach, P. Habenberger, S. Blencke, H. Gutbrod, K. Salassidis, M. Stein-Gerlach, A. Missio, M. Cotten, and H. Daub. 2003. An efficient proteomics method to identify the cellular targets of protein kinase inhibitors. Proc. Natl. Acad. Sci. USA 100: 15434-15439.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 15434-15439
-
-
Godl, K.1
Wissing, J.2
Kurtenbach, A.3
Habenberger, P.4
Blencke, S.5
Gutbrod, H.6
Salassidis, K.7
Stein-Gerlach, M.8
Missio, A.9
Cotten, M.10
Daub, H.11
-
51
-
-
36549040859
-
The selectivity of protein kinase inhibitors: A further update
-
Bain, J., L. Plater, M. Elliott, N. Shpiro, C. J. Hastie, H. McLauchlan, I. Klevernic, J. S. Arthur, D. R. Alessi, and P. Cohen. 2007. The selectivity of protein kinase inhibitors: a further update. Biochem. J. 408: 297-315.
-
(2007)
Biochem. J.
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
McLauchlan, H.6
Klevernic, I.7
Arthur, J.S.8
Alessi, D.R.9
Cohen, P.10
-
52
-
-
0033532146
-
Reconstitution of Btk signaling by the atypical tec family tyrosine kinases Bmx and Txk
-
Tomlinson, M. G., T. Kurosaki, A. E. Berson, G. H. Fujii, J. A. Johnston, and J. B. Bolen. 1999. Reconstitution of Btk signaling by the atypical tec family tyrosine kinases Bmx and Txk. J. Biol. Chem. 274: 13577-13585.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13577-13585
-
-
Tomlinson, M.G.1
Kurosaki, T.2
Berson, A.E.3
Fujii, G.H.4
Johnston, J.A.5
Bolen, J.B.6
-
53
-
-
0034606219
-
Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk
-
Ellmeier, W., S. Jung, M. J. Sunshine, F. Hatam, Y. Xu, D. Baltimore, H. Mano, and D. R. Littman. 2000. Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk. J. Exp. Med. 192: 1611-1624.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1611-1624
-
-
Ellmeier, W.1
Jung, S.2
Sunshine, M.J.3
Hatam, F.4
Xu, Y.5
Baltimore, D.6
Mano, H.7
Littman, D.R.8
-
54
-
-
0028866022
-
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor
-
Grell, M., E. Douni, H. Wajant, M. Löhden, M. Clauss, B. Maxeiner, S. Georgopoulos, W. Lesslauer, G. Kollias, K. Pfizenmaier, and P. Scheurich. 1995. The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor. Cell 83: 793-802.
-
(1995)
Cell
, vol.83
, pp. 793-802
-
-
Grell, M.1
Douni, E.2
Wajant, H.3
Löhden, M.4
Clauss, M.5
Maxeiner, B.6
Georgopoulos, S.7
Lesslauer, W.8
Kollias, G.9
Pfizenmaier, K.10
Scheurich, P.11
-
55
-
-
49049106608
-
Type 1 TNF receptor forms a complex with and uses Jak2 and c-Src to selectively engage signaling pathways that regulate transcription factor activity
-
Pincheira, R., A. F. Castro, O. N. Ozes, P. S. Idumalla, and D. B. Donner. 2008. Type 1 TNF receptor forms a complex with and uses Jak2 and c-Src to selectively engage signaling pathways that regulate transcription factor activity. J. Immunol. 181: 1288-1298.
-
(2008)
J. Immunol.
, vol.181
, pp. 1288-1298
-
-
Pincheira, R.1
Castro, A.F.2
Ozes, O.N.3
Idumalla, P.S.4
Donner, D.B.5
-
56
-
-
3142665469
-
TNF activates Syk protein tyrosine kinase leading to TNF-induced MAPK activation, NF-kappaB activation, and apoptosis
-
Takada, Y., and B. B. Aggarwal. 2004. TNF activates Syk protein tyrosine kinase leading to TNF-induced MAPK activation, NF-kappaB activation, and apoptosis. J. Immunol. 173: 1066-1077. (Pubitemid 38924281)
-
(2004)
Journal of Immunology
, vol.173
, Issue.2
, pp. 1066-1077
-
-
Takada, Y.1
Aggarwal, B.B.2
-
57
-
-
0028267287
-
Modulation of the cytotoxic activity of tumor necrosis factor by protein tyrosine kinase and protein tyrosine phosphatase inhibitors
-
Mishra, S., R. Mathur, and A. W. Hamburger. 1994. Modulation of the cytotoxic activity of tumor necrosis factor by protein tyrosine kinase and protein tyrosine phosphatase inhibitors. Lymphokine Cytokine Res. 13: 77-83.
-
(1994)
Lymphokine Cytokine Res.
, vol.13
, pp. 77-83
-
-
Mishra, S.1
Mathur, R.2
Hamburger, A.W.3
-
58
-
-
71149105333
-
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction
-
Haas, T. L., C. H. Emmerich, B. Gerlach, A. C. Schmukle, S. M. Cordier, E. Rieser, R. Feltham, J. Vince, U. Warnken, T. Wenger, et al. 2009. Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol. Cell 36: 831-844.
-
(2009)
Mol. Cell
, vol.36
, pp. 831-844
-
-
Haas, T.L.1
Emmerich, C.H.2
Gerlach, B.3
Schmukle, A.C.4
Cordier, S.M.5
Rieser, E.6
Feltham, R.7
Vince, J.8
Warnken, U.9
Wenger, T.10
-
59
-
-
33750973379
-
BTKbase: The mutation database for X-linked agammaglobulinemia
-
Väliaho, J., C. I. Smith, and M. Vihinen. 2006. BTKbase: the mutation database for X-linked agammaglobulinemia. Hum. Mutat. 27: 1209-1217.
-
(2006)
Hum. Mutat.
, vol.27
, pp. 1209-1217
-
-
Väliaho, J.1
Smith, C.I.2
Vihinen, M.3
-
60
-
-
0345447618
-
Function of Bruton's tyrosine kinase during B cell development is partially independent of its catalytic activity
-
Middendorp, S., G. M. Dingjan, A. Maas, K. Dahlenborg, and R. W. Hendriks. 2003. Function of Bruton's tyrosine kinase during B cell development is partially independent of its catalytic activity. J. Immunol. 171: 5988-5996.
-
(2003)
J. Immunol.
, vol.171
, pp. 5988-5996
-
-
Middendorp, S.1
Dingjan, G.M.2
Maas, A.3
Dahlenborg, K.4
Hendriks, R.W.5
-
61
-
-
38049084406
-
Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase
-
Pan, Z., H. Scheerens, S. J. Li, B. E. Schultz, P. A. Sprengeler, L. C. Burrill, R. V. Mendonca, M. D. Sweeney, K. C. Scott, P. G. Grothaus, et al. 2007. Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase. ChemMedChem 2: 58-61.
-
(2007)
ChemMedChem
, vol.2
, pp. 58-61
-
-
Pan, Z.1
Scheerens, H.2
Li, S.J.3
Schultz, B.E.4
Sprengeler, P.A.5
Burrill, L.C.6
Mendonca, R.V.7
Sweeney, M.D.8
Scott, K.C.9
Grothaus, P.G.10
-
62
-
-
0036617187
-
Lessons from animal models of arthritis
-
Van den Berg, W. B. 2002. Lessons from animal models of arthritis. Curr. Rheumatol. Rep. 4: 232-239.
-
(2002)
Curr. Rheumatol. Rep.
, vol.4
, pp. 232-239
-
-
Van Den Berg, W.B.1
-
63
-
-
0021352139
-
Flare-up of antigen-induced arthritis in mice after challenge with intravenous antigen: Studies on the characteristics of and mechanisms involved in the reaction
-
Lens, J. W., W. B. van den Berg, and L. B. van de Putte. 1984. Flare-up of antigen-induced arthritis in mice after challenge with intravenous antigen: studies on the characteristics of and mechanisms involved in the reaction. Clin. Exp. Immunol. 55: 287-294.
-
(1984)
Clin. Exp. Immunol.
, Issue.55
, pp. 287-294
-
-
Lens, J.W.1
Van Den Berg, W.B.2
Van De Putte, L.B.3
-
64
-
-
0000915343
-
The production of arthritis in rabbits by an immunological reaction to fibrin
-
Dumonde, D. C., and L. E. Glynn. 1962. The production of arthritis in rabbits by an immunological reaction to fibrin. Br. J. Exp. Pathol. 43: 373-383.
-
(1962)
Br. J. Exp. Pathol.
, vol.43
, pp. 373-383
-
-
Dumonde, D.C.1
Glynn, L.E.2
|