Bmx tyrosine kinase is specifically expressed in the endocardium and the endothelium of large arteries

Circulation

Volumn 96, Issue 6, 1997, Pages 1729-1732

  Ekman, Niklas ^b   Lymboussaki, Athina ^b   Västrik, Imre ^b   Sarvas, Krista ^b   Kaipainen, Arja ^b   Alitalo, Kari ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b NONE

Author keywords

Endocardium; Endothelium; Genes; Signal transduction

Indexed keywords

PROTEIN TYROSINE KINASE;

ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTICLE; ENDOCARDIUM; ENZYME SPECIFICITY; GENE ISOLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 0030756590     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.96.6.1729     Document Type: Article

References (11)

1. Mustonen T, Alitalo K. Endothelial receptor tyrosine kinases involved in angiogenesis. J Cell Biol. 1995;129:895-898.
2. Vihinen M, Smith E. Structural aspects of signal transduction in B-cells. Immunology. 1996;16:251-274.
3. Musacchio A, Gibson T, Rice P, Thompson J, Saraste M. The PH domain: a common piece in the structural patchwork of signalling proteins. Trends Biochem Sci. 1993;18:343-348.
4. Mano H, Ishikawa F, Nishida J, Hirai H, Takaku F. A novel protein-tyrosine kinase, tec, is preferentially expressed in liver. Oncogene. 1990;5:1781-1786.
5. Gibson S, Leung B, Squire JA, Hill M, Arima N, Goss P, Hogg D, Mills GB. Identification, cloning, and characterization of a novel human T-cell-specific tyrosine kinase located at the hematopoietin complex on chromosome 5q. Blood. 1993;82:1561-1572.
6. de Weers M, Verschuren MC, Kraakman ME, Mensink RG, Schuurman RK, van Dongen JJ, Hendriks RW. The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stages. Eur J Immunol. 1993;23: 3109-3114.
7. Sommers CL, Huang K, Shores EW, Grinberg A, Charlick DA, Kozak CA, Love PE. Murine txk: a protein tyrosine kinase gene regulated by T cell activation. Oncogene. 1995;11:245-251.
8. Tamagnone L, Lahtinen I, Mustonen T, Virtaneva K, Francis F, Muscatelli F, Alitalo R, Smith CI, Larsson C, Alitalo K. BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2. Oncogene. 1994;9: 3683-3688.
9. Kaipainen A, Korhonen J, Pajusola K, Aprelikova O, Persico MG, Terman BI, Alitalo K. The related FLT4, FLT1, and KDR receptor tyrosine kinases show distinct expression patterns in human fetal endothelial cells. J Exp Med. 1993;178:2077-2088.
10. Kaukonen J, Lahtinen I, Laine S, Alitalo K, Palotie A. Bmx tyrosine kinase gene is expressed in granulocytes and myeloid leukemias. Br J Haematol. 1996;94:455-460.
11. Tsukada S, Simon MI, Witte ON, Katz A. Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase. Proc Natl Acad Sci U S A. 1994;91:11256-11260.