Etk/Bmx Transactivates Vascular Endothelial Growth Factor 2 and Recruits Phosphatidylinositol 3-Kinase to Mediate the Tumor Necrosis Factor-induced Angiogenic Pathway

Journal of Biological Chemistry

Volumn 278, Issue 51, 2003, Pages 51267-51276

  Zhang, Rong ^a   Xu, Yingqian ^a   Ekman, Niklas ^b   Wu, Zhenhua ^c   Wu, Jiong ^d   Alitalo, Kari ^b   Min, Wang ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF ROCHESTER   (United States)

^d CELL SIGNALING TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES; SIGNALING; TUMORS;

PHOSPHORYLATION;

BIOCHEMISTRY;

ANGIOGENIC FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEIN TYROSINE KINASE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 2; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ARTICLE; CALCIUM MOBILIZATION; CELL MIGRATION; COMPLEX FORMATION; CYTOKINE RELEASE; ENDOTHELIUM CELL; ENZYME MECHANISM; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; MACROPHAGE ACTIVATION; MEDIATOR RELEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSACTIVATION; VASCULAR ENDOTHELIUM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CATTLE; CELL MOVEMENT; ENDOTHELIAL CELLS; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 0347065353     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310678200     Document Type: Article

References (50)

1. Leibovich, S. J., Polverini, P. J., Shepard, H. M., Wiseman, D. M., Shively, V., and Nuseir, N. (1987) Nature 329, 630-632
2. Lee, W. S., Jain, M. K., Arkonac, B. M., Zhang, D., Shaw, S. Y., Kashiki, S., Maemura, K., Lee, S. L., Hollenberg, N. K., Lee, M. E., and Haber, E. (1998) Circ. Res. 82, 845-851
3. Arras, M., Ito, W. D., Scholz, D., Winkler, B., Schaper, J., and Schaper, W. (1998) J. Clin. Invest. 101, 40-50
4. Li, J., Post, M., Volk, R., Gao, Y., Li, M., Metais, C., Sato, K., Tsai, J., Aird, W., Rosenberg, R. D., Hampton, T. G., Sellke, F., Carmeliet, P., and Simons, M. (2000) Nat. Med. 6, 49-55
5. Sarma, V., Wolf, F. W., Marks, R. M., Shows, T. B., and Dixit, V. M. (1992) J. Immunol. 148, 3302-3312
6. Frater-Schroder, M., Risau, W., Hallmann, R., Gautschi, P., and Bohlen, P. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 5277-5281
7. Koch, A. E. (1998) Arthritis Rheum. 41, 951-962
8. Keffer, J., Probert, L., Cazlaris, H., Georgopoulos, S., Kaslaris, E., Kioussis, D., and Kollias, G. (1991) EMBO J. 10, 4025-4031
9. Carmeliet, P., and Jain, R. K. (2000) Nature 407, 249-257
10. Walsh, D. A. (1999) Rheumotology 38, 103-112
11. Giraudo, E., Primo, L., Audero, E., Gerber, H. P., Koolwijk, P., Soker, S., Klagsbrun, M., Ferrara, N., and Bussolino, F. (1998) J. Biol. Chem. 273, 22128-22135
12. Ristimaki, A., Narko, K., Enholm, B., Joukov, V., and Alitalo, K. (1998) J. Biol. Chem. 273, 8413-8418
13. Alavi, A., Hood, J. D., Frausto, R., Stupack, D. G., and Cheresh, D. A. (2003) Science 301, 94-96
14. Matsumoto, T., and Claesson-Welsh, L. (2001) Science's STKE http://www.stke.org/cgi/content/full/OC_sigtrans;2001/112/re21
15. Ferrara, N., Gerber, H. P., and LeCouter, J. (2003) Nat. Med. 9, 669-676
16. Wu, L. W., Mayo, L. D., Dunbar, J. D., Kessler, K. M., Baerwald, M. R., Jaffe, E. A., Wang, D., Warren, R. S., and Donner, D. B. (2000) J. Biol. Chem. 275, 5096-5103
17. Takahashi, T., Yamaguchi, S., Chida, K., and Shibuya, M. (2001) EMBO J. 20, 2768-2778
18. Meyer, R. D., Latz, C., and Rahimi, N. (2003) J. Biol. Chem. 278, 16347-16355
19. Dougher, M., and Terman, B. I. (1999) Oncogene 18, 1619-1627
20. Dayanir, V., Meyer, R. D., Lashkari, K., and Rahimi, N. (2001) J. Biol. Chem. 276, 17686-17692
21. Cheng, N., and Chen, J. (2001) J. Biol. Chem. 276, 13771-13777
22. Maceyka, M., Payne, S. G., Milstien, S., and Spiegel, S. (2002) Biochim. Biophys. Acta 1585, 193-201
23. Pan, S., An, P., Zhang, R., He, X., Yin, G., and Min, W. (2002) Mol. Cell. Biol. 22, 7512-7523
24. Tamagnone, L., Lahtinen, I., Mustonen, T., Virtaneva, K., Francis, F., Muscatelli, F., Alitalo, R., Smith, C. I., Larsson, C., and Alitalo, K. (1994) Oncogene 9, 3683-3688
25. Qiu, Y., and Kung, H. J. (2000) Oncogene 19, 5651-5661
26. Mano, H. (1999) Cytokine Growth Factor Rev. 10, 267-280
27. Qiu, Y., Robinson, D., Pretlow, T. G., and Kung, H. J. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3644-3649
28. Chau, C. H., Chen, K. Y., Deng, H. T., Kim, K. J., Hosoya, K., Terasaki, T., Shih, H. M., and Ann, D. K. (2002) Oncogene 21, 8817-8829
29. Tsai, Y. T., Su, Y. H., Fang, S. S., Huang, T. N., Qiu, Y., Jou, Y. S., Shih, H. M., Kung, H. J., and Chen, R. H. (2000) Mol. Cell. Biol. 20, 2043-2054
30. Mao, J., Xie, W., Yuan, H., Simon, M. I., Mano, H., and Wu, D. (1998) EMBO J. 17, 5638-5646
31. Chen, R., Kim, O., Li, M., Xiong, X., Guan, J. L., Kung, H. J., Chen, H., Shimizu, Y., and Qiu, Y. (2001) Nat. Cell Biol. 3, 439-444
32. Liu, Y., Yin, G., Surapisitchat, J., Berk, B. C., and Min, W. (2001) J. Clin. Invest. 107, 917-923
33. Madge, L. A., and Pober, J. S. (2000) J. Biol. Chem. 275, 15458-15465
34. Takahashi-Tezuka, M., Hibi, M., Fujitani, Y., Fukada, T., Yamaguchi, T., and Hirano, T. (1997) Oncogene 14, 2273-2282
35. Rajantie, I., Ekman, N., Iljin, K., Arighi, E., Gunji, Y., Kaukonen, J., Palotie, A., Dewerchin, M., Carmeliet, P., and Alitalo, K. (2001) Mol. Cell. Biol. 21, 4647-4655
36. Bagheri-Yarmand, R., Mandal, M., Taludker, A. H., Wang, R. A., Vadlamudi, R. K., Kung, H. J., and Kumar, R. (2001) J. Biol. Chem. 276, 29403-29409
37. Kiosses, W. B., Hood, J., Yang, S., Gerritsen, M. E., Cheresh, D. A., Alderson, N., and Schwartz, M. A. (2002) Circ. Res. 90, 697-702
38. Andreotti, A. H., Bunnell, S. C., Feng, S., Berg, L. J., and Schreiber, S. L. (1997) Nature 385, 93-97
39. Ekman, N., Lymboussaki, A., Vastrik, I., Sarvas, K., Kaipainen, A., and Alitalo, K. (1997) Circulation 96, 1729-1732
40. Kim, O., Yang, J., and Qiu, Y. (2002) J. Biol. Chem. 277, 30066-30071
41. Qi, J. H., and Claesson-Welsh, L. (2001) Exp. Cell Res. 263, 173-182
42. Gille, H., Kowalski, J., Yu, L., Chen, H., Pisabarro, T., Davis-Smyth, T., and Ferrana, N. (2000) EMBO J. 19, 40664-44073
43. Dimmeler, S., Dernbach, E., and Zeiher, A. M. (2000) FEBS Lett. 477, 258-262
44. Kureishi, Y., Luo, Z., Shiojima, I., Bialik, A., Fulton, D., Lefer, D. J., Sessa, W. C., and Walsh, K. (2000) Nat. Med. 6, 1004-1010
45. Guo, D. Q., Wu, L. W., Dunbar, J. D., Ozes, O. N., Mayo, L. D., Kessler, K. M., Gustin, J. A., Baerwald, M. R., Jaffe, E. A., Warren, R. S., and Donner, D. B. (2000) J. Biol. Chem. 275, 11216-11221
46. Iruela-Arispe, M. L., and Dvorak, H. F. (1997) Thromb. Haemostasis 78, 672-677
47. Lee, M. J., Thangada, S., Claffey, K. P., Ancellin, N., Liu, C. H., Kluk, M., Volpi, M., Sha'afi, R. I., and Hla, T. (1999) Cell 99, 301-312
48. Tanimoto, T., Jin, Z. G., and Berk, B. C. (2002) J. Biol. Chem. 277, 42997-4300
49. Autiero, M., Waltenberger, J., Communi, D., Kranz, A., Moons, L., Lambrechts, D., Kroll, J., Plaisance, S., De Mol, M., Bono, F., Kliche, S., Fellbrich, G., Ballmer-Hofer, K., Maglione, D., Mayr-Beyrle, U., Dewerchin, M., Dombrowski, S., Stanimirovic, D., Van Hummelen, P., Dehio, C., Hicklin, D. J., Persico, G., Herbert, J. M., Shibuya, M., Collen, D., Conway, E. M., and Carmeliet, P. (2003) Nat. Med. 9, 936-943
50. Jin, Z. G., Ueba, H., Tanimoto, T., Lungu, A., Frame, M. D., and Berk, B. C. (2003) Cir. Res. 93, 354-363