Norcantharidin analogues with nematocidal activity in Haemonchus contortus

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 11, 2011, Pages 3277-3281

  Campbell, Bronwyn E ^a   Tarleton, Mark ^b   Gordon, Christopher P ^b   Sakoff, Jennette A ^c   Gilbert, Jayne ^c   McCluskey, Adam ^b   Gasser, Robin B ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c CALVARY MATER NEWCASTLE HOSPITAL   (Australia)

Author keywords

Haemonchus contortus; Nematocidal drugs; Norcantharidin analogues

Indexed keywords

2 (3,4 DICHLOROPHENYL) 3 (1H PYRROL 2 YL)ACRYLONITRILE; 2 (4 CHLOROPHENYL) 3 (1H PYRROL 2 YL)ACRYLONITRILE; 2 (4 FLUOROPHENYL) 3 (1H PYRROL 2 YL)ACRYLONITRILE; 2 PHENYL 3 (1H PYRROL 2 YL)ACRYLONITRILE; 4 (4 METHYL) 3 ETHYL 2 METHYL 5 PHENYLFURAN 10 OXA 4 AZATRICYCLO(5.2.1)DECANE 3,5 DIONE; ANTHELMINTIC AGENT; ANTINEMATODAL AGENT; N DECYL 7 OXABICYCLO(2.2.1)HEPTANE 2,3 DICARBOXIMIDE; N OCTYL 7 OXABICYCLO(2.2.1)HEPTANE 2,3 DICARBOXIMIDE; NORCANTHARIDIN; UNCLASSIFIED DRUG;

ANTHELMINTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; HAEMONCHUS CONTORTUS; HUMAN; HUMAN CELL; LD 50; NONHUMAN;

ANIMALS; ANTINEMATODAL AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; CELL LINE; CELL LINE, TUMOR; DRUG DESIGN; HAEMONCHUS; HUMANS; MOLECULAR STRUCTURE; NEOPLASMS;

HAEMONCHUS CONTORTUS; NEMATODA;

EID: 79956090050     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.04.031     Document Type: Article

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