-
1
-
-
0038049079
-
Anthroponotic cutaneous leishmaniasis, Kabul, Afghanistan
-
Reithinger R., et al. Anthroponotic cutaneous leishmaniasis, Kabul, Afghanistan. Emerg. Infect. Dis. 9:2003;727-729.
-
(2003)
Emerg. Infect. Dis.
, vol.9
, pp. 727-729
-
-
Reithinger, R.1
-
2
-
-
0029659734
-
The epidemic of visceral leishmaniasis in western upper Nile, southern Sudan: Course and impact from 1984 to 1994
-
Seaman J., et al. The epidemic of visceral leishmaniasis in western upper Nile, southern Sudan: course and impact from 1984 to 1994. Int. J. Epidemiol. 25:1996;862-871.
-
(1996)
Int. J. Epidemiol.
, vol.25
, pp. 862-871
-
-
Seaman, J.1
-
4
-
-
0033517487
-
Leishmaniasis
-
Herwaldt B.L. Leishmaniasis. Lancet. 354:1999;1191-1199.
-
(1999)
Lancet
, vol.354
, pp. 1191-1199
-
-
Herwaldt, B.L.1
-
5
-
-
0033980453
-
A comparison of the activities of three amphotericin B lipid formulations against experimental visceral and cutaneous leishmaniasis
-
Yardley V., Croft S.L. A comparison of the activities of three amphotericin B lipid formulations against experimental visceral and cutaneous leishmaniasis. Int. J. Antimicrob. Agents. 13:2000;243-248.
-
(2000)
Int. J. Antimicrob. Agents
, vol.13
, pp. 243-248
-
-
Yardley, V.1
Croft, S.L.2
-
6
-
-
0034913328
-
Clinical and experimental advances in treatment of visceral leishmaniasis
-
Murray H.W. Clinical and experimental advances in treatment of visceral leishmaniasis. Antimicrob. Agents Chemother. 45:2001;2185-2197.
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 2185-2197
-
-
Murray, H.W.1
-
7
-
-
0142258171
-
Leishmaniasis - Current chemotherapy and recent advances in the search for novel drugs
-
Croft S., et al. Leishmaniasis - current chemotherapy and recent advances in the search for novel drugs. Trends Parasitol. 19:2003;502-508.
-
(2003)
Trends Parasitol.
, vol.19
, pp. 502-508
-
-
Croft, S.1
-
8
-
-
0010655513
-
The next epidemic
-
J.M. et al. Mann. Harvard University Press
-
Garrett L. The next epidemic. Mann J.M., et al. AIDS in the World. 1992;825-839 Harvard University Press.
-
(1992)
AIDS in the World
, pp. 825-839
-
-
Garrett, L.1
-
9
-
-
0042268077
-
Immunoenhancement combined with amphotericin B as treatment in experimental visceral leishmaniasis
-
Murray H.W., et al. Immunoenhancement combined with amphotericin B as treatment in experimental visceral leishmaniasis. Antimicrob. Agents Chemother. 47:2003;2513-2517.
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 2513-2517
-
-
Murray, H.W.1
-
10
-
-
0038004738
-
Making better drugs: Decision gates in non-clinical drug development
-
Pritchard J.F., et al. Making better drugs: decision gates in non-clinical drug development. Nat. Rev. Drug Discov. 2:2003;542-553.
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 542-553
-
-
Pritchard, J.F.1
-
11
-
-
0037457250
-
Drug target validation: Hitting the target
-
341, 343, 345
-
Smith C. Drug target validation: hitting the target. Nature. 2003;422. 341, 343, 345.
-
(2003)
Nature
, pp. 422
-
-
Smith, C.1
-
12
-
-
0034677966
-
Drug discovery: A historical perspective
-
Drews J. Drug discovery: a historical perspective. Science. 287:2000;1960-1964.
-
(2000)
Science
, vol.287
, pp. 1960-1964
-
-
Drews, J.1
-
13
-
-
0038387389
-
Hit and lead generation: Beyond high-throughput screening
-
Bleicher K.H., et al. Hit and lead generation: beyond high-throughput screening. Nat. Rev. Drug Discov. 2:2003;369-378.
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 369-378
-
-
Bleicher, K.H.1
-
14
-
-
0027287506
-
Rational design of potent sialidase-based inhibitors of influenza virus replication
-
von Itzstein M., et al. Rational design of potent sialidase-based inhibitors of influenza virus replication. Nature. 363:1993;418-423.
-
(1993)
Nature
, vol.363
, pp. 418-423
-
-
Von Itzstein, M.1
-
15
-
-
0141520538
-
Developmentally induced changes of the proteome in the protozoan parasite Leishmania donovani
-
Bente M., et al. Developmentally induced changes of the proteome in the protozoan parasite Leishmania donovani. Proteomics. 3:2003;1811-1829.
-
(2003)
Proteomics
, vol.3
, pp. 1811-1829
-
-
Bente, M.1
-
16
-
-
0036668518
-
A proteomic approach to identify developmentally regulated proteins in Leishmania infantum
-
El Fakhry Y., et al. A proteomic approach to identify developmentally regulated proteins in Leishmania infantum. Proteomics. 2:2002;1007-1017.
-
(2002)
Proteomics
, vol.2
, pp. 1007-1017
-
-
El Fakhry, Y.1
-
17
-
-
0035997275
-
Establishing two-dimensional gels for the analysis of Leishmania proteomes
-
Acestor N., et al. Establishing two-dimensional gels for the analysis of Leishmania proteomes. Proteomics. 2:2002;877-879.
-
(2002)
Proteomics
, vol.2
, pp. 877-879
-
-
Acestor, N.1
-
18
-
-
0141909066
-
Proteome mapping of the protozoan parasite Leishmania and application to the study of drug targets and resistance mechanisms
-
Drummelsmith J., et al. Proteome mapping of the protozoan parasite Leishmania and application to the study of drug targets and resistance mechanisms. Mol. Cell. Proteomics. 2:2003;146-155.
-
(2003)
Mol. Cell. Proteomics
, vol.2
, pp. 146-155
-
-
Drummelsmith, J.1
-
19
-
-
0037394124
-
Designing screens: How to make your hits a hit
-
Walters W.P., Namchuk M. Designing screens: how to make your hits a hit. Nat. Rev. Drug Discov. 2:2003;259-266.
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 259-266
-
-
Walters, W.P.1
Namchuk, M.2
-
20
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
Lipinski C.A., et al. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 46:2001;3-26.
-
(2001)
Adv. Drug Deliv. Rev.
, vol.46
, pp. 3-26
-
-
Lipinski, C.A.1
-
21
-
-
0033179183
-
Recognizing molecules with drug-like properties
-
Walters W.P., et al. Recognizing molecules with drug-like properties. Curr. Opin. Chem. Biol. 3:1999;384-387.
-
(1999)
Curr. Opin. Chem. Biol.
, vol.3
, pp. 384-387
-
-
Walters, W.P.1
-
22
-
-
0036606483
-
Principles of docking: An overview of search algorithms and a guide to scoring functions
-
Halperin I., et al. Principles of docking: An overview of search algorithms and a guide to scoring functions. Proteins. 47:2002;409-443.
-
(2002)
Proteins
, vol.47
, pp. 409-443
-
-
Halperin, I.1
-
23
-
-
0036051992
-
High-throughput crystallography for lead discovery in drug design
-
Blundell T.L., et al. High-throughput crystallography for lead discovery in drug design. Nat. Rev. Drug Discov. 1:2002;45-54.
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 45-54
-
-
Blundell, T.L.1
-
24
-
-
0028297112
-
Application of the three-dimensional structures of protein target molecules in structure-based drug design
-
Greer J., et al. Application of the three-dimensional structures of protein target molecules in structure-based drug design. J. Med. Chem. 37:1994;1035-1054.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 1035-1054
-
-
Greer, J.1
-
25
-
-
0036835460
-
Integration of virtual and high-throughput screening
-
Bajorath J. Integration of virtual and high-throughput screening. Nat. Rev. Drug Discov. 1:2002;882-894.
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 882-894
-
-
Bajorath, J.1
-
26
-
-
0035927424
-
Adenosine analogues as selective inhibitors of glyceraldehyde-3- phosphate dehydrogenase of Trypanosomatidae via structure-based drug design
-
Bressi J.C., et al. Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design. J. Med. Chem. 44:2001;2080-2093.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 2080-2093
-
-
Bressi, J.C.1
-
27
-
-
0038336897
-
Application and limitations of x-ray crystallographic data in structure-based ligand and drug design
-
Davis A.M., et al. Application and limitations of x-ray crystallographic data in structure-based ligand and drug design. Angew. Chem. Int. Ed. Engl. 42:2003;2718-2736.
-
(2003)
Angew. Chem. Int. Ed. Engl.
, vol.42
, pp. 2718-2736
-
-
Davis, A.M.1
-
28
-
-
0037963683
-
Concepts of immunostimulation to increase antiparasitic drug action
-
Masihi K.N. Concepts of immunostimulation to increase antiparasitic drug action. Parasitol. Res. 90:(Suppl. 2):2003;S97-S104.
-
(2003)
Parasitol. Res.
, vol.90
, Issue.SUPPL. 2
-
-
Masihi, K.N.1
-
29
-
-
0036839677
-
Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy
-
Murray H.W., et al. Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy. Infect. Immun. 70:2002;6284-6293.
-
(2002)
Infect. Immun.
, vol.70
, pp. 6284-6293
-
-
Murray, H.W.1
-
30
-
-
0242286545
-
Modulation of T cell costimulation as immunotherapy or immunochemotherapy in experimental visceral leishmaniasis
-
Murray H.W., et al. Modulation of T cell costimulation as immunotherapy or immunochemotherapy in experimental visceral leishmaniasis. Infect. Immun. 71:2003;6453-6462.
-
(2003)
Infect. Immun.
, vol.71
, pp. 6453-6462
-
-
Murray, H.W.1
-
31
-
-
0033057209
-
Treatment of experimental leishmaniasis with the immunomodulators imiquimod and S-28463: Efficacy and mode of action
-
Buates S., Matlashewski G. Treatment of experimental leishmaniasis with the immunomodulators imiquimod and S-28463: efficacy and mode of action. J. Infect. Dis. 179:1999;1485-1494.
-
(1999)
J. Infect. Dis.
, vol.179
, pp. 1485-1494
-
-
Buates, S.1
Matlashewski, G.2
-
32
-
-
0035577828
-
Successful treatment of drug-resistant cutaneous leishmaniasis in humans by use of imiquimod, an immunomodulator
-
Arevalo I., et al. Successful treatment of drug-resistant cutaneous leishmaniasis in humans by use of imiquimod, an immunomodulator. Clin. Infect. Dis. 33:2001;1847-1851.
-
(2001)
Clin. Infect. Dis.
, vol.33
, pp. 1847-1851
-
-
Arevalo, I.1
-
33
-
-
0345839252
-
Where will new antibiotics come from?
-
Walsh C. Where will new antibiotics come from? Nat. Rev. Microbiol. 1:2003;65-70.
-
(2003)
Nat. Rev. Microbiol.
, vol.1
, pp. 65-70
-
-
Walsh, C.1
-
34
-
-
0141716855
-
Drug companies snub antibiotics as pipeline threatens to run dry
-
Clarke T. Drug companies snub antibiotics as pipeline threatens to run dry. Nature. 425:2003;225.
-
(2003)
Nature
, vol.425
, pp. 225
-
-
Clarke, T.1
|