Library synthesis and cytotoxicity of a family of 2-phenylacrylonitriles and discovery of an estrogen dependent breast cancer lead compound

MedChemComm

Volumn 2, Issue 1, 2011, Pages 31-37

  Tarleton, Mark ^a   Gilbert, Jayne ^b   Robertson, Mark J ^a   McCluskey, Adam ^a   Sakoff, Jennette A ^b  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b NEWCASTLE MATER HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3,4 DICHLOROPHENYL) 3 (4 METHOXYPHENYL)ACRYLONITRILE; 2 (3,4 DICHLOROPHENYL) 3 (4 NITROPHENYL)ACRYLONITRILE; 2 PHENYL 3 (1H PYRROL 2 CARBONYL)ACRYLONITRILE DERIVATIVE; 2 PHENYL 3 (1H PYRROL 2 YL)ACRYLONITRILE DERIVATIVE; 2 PHENYL 3 (1H PYRROL 2 YL)PROPANENITRILE DERIVATIVE; 2 PHENYLACRYLONITRILE; ACRYLONITRILE; ESTROGEN RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CELL STRAIN HT29; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; PHARMACOPHORE; PRIORITY JOURNAL;

EID: 79952360822     PISSN: 20402503     EISSN: 20402511     Source Type: Journal    
DOI: 10.1039/c0md00147c     Document Type: Article

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