An Ugi-intramolecular Diels-Alder route to highly substituted tetrahydroepoxyisoindole carboxamides

Tetrahedron

Volumn 67, Issue 2, 2011, Pages 554-561

  Gordon, Christopher P ^a   Young, Kelly A ^a   Robertson, Mark J ^a   Hill, Timothy A ^a   McCluskey, Adam ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Diels Alder addition; Medicinal chemistry scaffold; Tricyclic lactams; Ugi condensation

Indexed keywords

1 NAPHTHYLAMINE; 2 (2 NAPHTHYL) 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(2 ETHOXY 2 OXOETHYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (4 CHLOROPHENYL) 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(2 ETHOXY 2 OXOETHYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (4 N,N DIMETHYLAMINOPROPYL) 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(PENTYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (4 N,N DIMETHYLAMINOPROPYL) 1,2,3,6 TETRAHYDRO 7 PENTYL 1 OXO N(PENTYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (4 NITROPHENYL) 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(2 ETHOXY 2 OXOETHYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (4 PHENOL) 1,2,3,6 TETRAHYDRO 7 PROPYL 1 OXO N(2 METHOXY 2 OXOETHYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (5 PENTANOL) 1,2,3,6 TETRAHYDRO 7 PROPYL 1 OXO N(2 METHOXY 2 OXOETHYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (BENZYL) 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(2 ETHOXY 2 OXOETHYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (BENZYL) 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(2 METHOXY 2 OXOETHYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (BENZYL) 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(2 TERT BUTOXY 2 OXOETHYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (BENZYL) 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(2 TOLY) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (BENZYL) 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(BUTYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (BENZYL) 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(CYCLOHEXYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (BENZYL) 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(PENTYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (BENZYL) 1,2,3,6 TETRAHYDRO 7 PROPYL 1 OXO N(2 NAPHTHYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 2 (OCTYL) 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(2 ETHOXY 2 OXOETHYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; 4 AMINOPHENOL; 4 CHLOROANILINE; 4 NITROANILINE; AMIDE; BENZYL 1,2,3,6 TETRAHYDRO 7 METHYL 1 OXO N(2 NAPHTHYL) 3A,6 EPOX 3AH ISOINDOLE 3 CARBOXAMIDE; BENZYLAMINE; FURFURAL; ISONITRILE DERIVATIVE; LACTAM; OCTYLAMINE; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DIELS ALDER REACTION; PRIORITY JOURNAL; UGI CONDENSATION;

ALNUS;

EID: 78650179401     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2010.10.042     Document Type: Article

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