메뉴 건너뛰기




Volumn 38, Issue 6, 2011, Pages 1597-1604

The novel resveratrol analog HS-1793-induced polyploid LNCaP prostate cancer cells are vulnerable to downregulation of Bcl-xL

Author keywords

Aurora B kinase; Bcl xL; Multinucleation; Polyploidy; Resveratrol analog

Indexed keywords

ANTINEOPLASTIC AGENT; AURORA B KINASE; HS 1793; PHENOL DERIVATIVE; PROTEIN BCL XL; UNCLASSIFIED DRUG;

EID: 79955874860     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.979     Document Type: Article
Times cited : (18)

References (41)
  • 2
    • 0034790052 scopus 로고    scopus 로고
    • Bcl-2 overexpression attenuates resveratrol-induced apoptosis in U937 cells by inhibition of caspase-3 activity
    • Park JW, Choi YJ, Suh SI, Baek WK, Suh MH and Jin IN: Bcl-2 overexpression attenuates resveratrol-induced apoptosis in U937 cells by inhibition of caspase-3 activity. Carcinogenesis 22: 1633-1639, 2001.
    • (2001) Carcinogenesis , vol.22 , pp. 1633-1639
    • Park, J.W.1    Choi, Y.J.2    Suh, S.I.3    Baek, W.K.4    Suh, M.H.5    Jin, I.N.6
  • 3
    • 0035408191 scopus 로고    scopus 로고
    • Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2
    • Tinhofer I, Bernhard D, Senfter M, Anether G, Loeffler M, Kroemer G, Kofler R, Csordas A and Greil R: Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2. FASEB J 15: 1613-1615, 2001.
    • (2001) FASEB J , vol.15 , pp. 1613-1615
    • Tinhofer, I.1    Bernhard, D.2    Senfter, M.3    Anether, G.4    Loeffler, M.5    Kroemer, G.6    Kofler, R.7    Csordas, A.8    Greil, R.9
  • 5
    • 33846070701 scopus 로고    scopus 로고
    • Syntheses of hydroxy substituted 2-phenyl-naphthalenes as inhibitors of tyrosinase
    • DOI 10.1016/j.bmcl.2006.10.025, PII S0960894X06011930
    • Song S, Lee H, Jin Y, Ha YM, Bae S and Chung HY: Syntheses of hydroxyl substituted 2-phenyl-naphthalenes as inhibitors of tyrosinase. Bioorg Med Chem Lett 17: 461-464, 2007. (Pubitemid 46073741)
    • (2007) Bioorganic and Medicinal Chemistry Letters , vol.17 , Issue.2 , pp. 461-464
    • Song, S.1    Lee, H.2    Jin, Y.3    Ha, Y.M.4    Bae, S.5    Chung, H.Y.6    Suh, H.7
  • 6
    • 62749159928 scopus 로고    scopus 로고
    • A novel resveratrol derivative, HS1793, overcomes the resistance conferred by Bcl-2 in human leukemic U937 cells
    • Jeong SH, Jo WS, Song S, Suh H, Seol SY, Leem SH, Kwon TKand Yoo YH: A novel resveratrol derivative, HS1793, overcomes the resistance conferred by Bcl-2 in human leukemic U937 cells. Biochem Pharmacol 77: 1337-1347, 2009.
    • (2009) Biochem Pharmacol , vol.77 , pp. 1337-1347
    • Jeong, S.H.1    Jo, W.S.2    Song, S.3    Suh, H.4    Seol, S.Y.5    Leem, S.H.6    Kwon, T.K.7    Yoo, Y.H.8
  • 8
    • 79952199253 scopus 로고    scopus 로고
    • Control of prostate cell growth, DNA damage and repair, and gene expression by resveratrol analogues, in vitro
    • Hsieh TC, Huang YC and Wu JM: Control of prostate cell growth, DNA damage and repair, and gene expression by resveratrol analogues, in vitro. Carcinogenesis 32: 93-101, 2011.
    • (2011) Carcinogenesis , vol.32 , pp. 93-101
    • Hsieh, T.C.1    Huang, Y.C.2    Wu, J.M.3
  • 9
    • 0036072056 scopus 로고    scopus 로고
    • Resveratrol induced serine phosphorylation of p53 causes apoptosis in a mutant p53 prostate cancer cell line
    • Lin HY, Shih A, Davis FB, Tang HY, Martino LJ, Bennett JA and Davis PJ: Resveratrol induced serine phosphorylation of p53 causes apoptosis in a mutant p53 prostate cancer cell line. J Urol 168: 748-755, 2002. (Pubitemid 34793357)
    • (2002) Journal of Urology , vol.168 , Issue.2 , pp. 748-755
    • Lin, H.-Y.1    Shih, A.2    Davis, F.B.3    Tang, H.-Y.4    Martino, L.J.5    Bennett, J.A.6    Davis, P.J.7
  • 10
    • 77958466159 scopus 로고    scopus 로고
    • Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines
    • Wang Y, Romigh T, He X, Orloff MS, Silverman RH, Heston WD and Eng C: Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines. Hum Mol Genet 19: 4319-4329, 2010.
    • (2010) Hum Mol Genet , vol.19 , pp. 4319-4329
    • Wang, Y.1    Romigh, T.2    He, X.3    Orloff, M.S.4    Silverman, R.H.5    Heston, W.D.6    Eng, C.7
  • 11
    • 0034073147 scopus 로고    scopus 로고
    • Grape-derived chemopreventive agent resveratrol decreases prostate-specific antigen (PSA) expression in LNCaP cells by an androgen receptor (AR)-independent mechanism
    • Hsieh TC and Wu JM: Grape-derived chemopreventive agent resveratrol decreases prostate-specific antigen (PSA) expression in LNCaP cells by an androgen receptor (AR)-independent mechanism. Anticancer Res 20: 225-228, 2000.
    • (2000) Anticancer Res , vol.20 , pp. 225-228
    • Hsieh, T.C.1    Wu, J.M.2
  • 12
    • 0035235736 scopus 로고    scopus 로고
    • Mitotic kinases as regulators of cell division and its checkpoints
    • Nigg EA: Mitotic kinases as regulators of cell division and its checkpoints. Nat Rev Mol Cell Biol 2: 21-32, 2001.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 21-32
    • Nigg, E.A.1
  • 15
    • 0031764068 scopus 로고    scopus 로고
    • Protein kinase profile of sperm and eggs: Cloning and characterization of two novel testis-specific protein kinases (AIE1, AIE2) related to yeast and fly chromosome segregation regulators
    • Tseng TC, Chen SH, Hsu YP and Tang TK: Protein kinase profile of sperm and eggs: cloning and characterization of two novel testis-specific protein kinases (AIE1, AIE2) related to yeast and fly chromosome segregation regulators. DNA Cell Biol 17: 823-833, 1998.
    • (1998) DNA Cell Biol , vol.17 , pp. 823-833
    • Tseng, T.C.1    Chen, S.H.2    Hsu, Y.P.3    Tang, T.K.4
  • 16
    • 0032213515 scopus 로고    scopus 로고
    • Multinuclearity and increased ploidy caused by overexpression of the Aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells
    • Tatsuka M, Katayama H, Ota T, Tanaka T, Odashima S, Suzuki F and Terada Y: Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells. Cancer Res 58: 4811-4816, 1998. (Pubitemid 28503674)
    • (1998) Cancer Research , vol.58 , Issue.21 , pp. 4811-4816
    • Tatsuka, M.1    Katayama, H.2    Ota, T.3    Tanaka, T.4    Odashima, S.5    Suzuki, F.6    Terada, Y.7
  • 19
    • 63449136392 scopus 로고    scopus 로고
    • The topoisomerase I poison CPT-11 enhances the effect of the Aurora B kinase inhibitor AZD1152 both in vitro and in vivo
    • Nair JS, de Stanchina E and Schwartz GK: The topoisomerase I poison CPT-11 enhances the effect of the Aurora B kinase inhibitor AZD1152 both in vitro and in vivo. Clin Cancer Res 15: 2022-2030, 2009.
    • (2009) Clin Cancer Res , vol.15 , pp. 2022-2030
    • Nair, J.S.1    De Stanchina, E.2    Schwartz, G.K.3
  • 20
    • 33747877023 scopus 로고    scopus 로고
    • The Aurora kinase inhibitor VX-680 induces endoreduplication and apoptosis preferentially in cells with compromised p53-dependent postmitotic checkpoint function
    • DOI 10.1158/0008-5472.CAN-05-3353
    • Gizatullin F, Yao Y, Kung V, Harding MW, Loda M and Shapiro GI: The Aurora kinase inhibitor VX-680 induces endoreduplication and apoptosis preferentially in cells with compromised p53-dependent postmitotic checkpoint function. Cancer Res 66: 7668-7677, 2006. (Pubitemid 44289225)
    • (2006) Cancer Research , vol.66 , Issue.15 , pp. 7668-7677
    • Gizatullin, F.1    Yao, Y.2    Kung, V.3    Harding, M.W.4    Loda, M.5    Shapiro, G.I.6
  • 21
    • 33744911634 scopus 로고    scopus 로고
    • Targeting aurora kinases for the treatment of prostate cancer
    • DOI 10.1158/0008-5472.CAN-05-2796
    • Lee EC, Frolov A, Li R, Ayala G and Greenberg NM: Targeting Aurora kinases for the treatment of prostate cancer. Cancer Res 66: 4996-5002, 2006. (Pubitemid 43844918)
    • (2006) Cancer Research , vol.66 , Issue.10 , pp. 4996-5002
    • Lee, E.C.Y.1    Frolov, A.2    Li, R.3    Ayala, G.4    Greenberg, N.M.5
  • 23
    • 0037143442 scopus 로고    scopus 로고
    • Regulation of human separase by securin binding and autocleavage
    • DOI 10.1016/S0960-9822(02)01073-4, PII S0960982202010734
    • Waizenegger I, Giménez-Abián JF, Wernic D and Peters JM: Regulation of human separase by securing binding and auto-cleavage. Curr Biol 12: 1368-1378, 2002. (Pubitemid 34915538)
    • (2002) Current Biology , vol.12 , Issue.16 , pp. 1368-1378
    • Waizenegger, I.C.1    Gimenez-Abian, J.F.2    Wernic, D.3    Peters, J.-M.4
  • 24
    • 0029658664 scopus 로고    scopus 로고
    • Expression of Bcl-x(L) and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage
    • Minn AJ, Boise LH and Thompson CB: Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage. Genes Dev 10: 2621-2631, 1996. (Pubitemid 26357228)
    • (1996) Genes and Development , vol.10 , Issue.20 , pp. 2621-2631
    • Minn, A.J.1    Boise, L.H.2    Thompson, C.B.3
  • 25
    • 0031931414 scopus 로고    scopus 로고
    • Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
    • Lanni JS and Jacks T: Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol Cell Biol 18: 1055-1064, 1998. (Pubitemid 28063440)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.2 , pp. 1055-1064
    • Lanni, J.S.1    Jacks, T.2
  • 26
    • 0034767429 scopus 로고    scopus 로고
    • Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1
    • Andreassen PR, Lohez OD, Lacroix FB and Margolis RL: Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1. Mol Biol Cell 12: 1315-1328, 2001. (Pubitemid 33044413)
    • (2001) Molecular Biology of the Cell , vol.12 , Issue.5 , pp. 1315-1328
    • Andreassen, P.R.1    Lohez, O.D.2    Lacroix, F.B.3    Margolis, R.L.4
  • 29
    • 0037406990 scopus 로고    scopus 로고
    • Does the intrinsic instability of aneuploid genomes have a causal role in cancer?
    • Matzke MA, Mette MF, Kanno T and Matzke AJ: Does the intrinsic instability of aneuploid genomes have a causal role in cancer? Trends Genet 19: 253-256, 2003.
    • (2003) Trends Genet , vol.19 , pp. 253-256
    • Matzke, M.A.1    Mette, M.F.2    Kanno, T.3    Matzke, A.J.4
  • 30
    • 35548935096 scopus 로고    scopus 로고
    • Limiting the Proliferation of Polyploid Cells
    • DOI 10.1016/j.cell.2007.10.024, PII S0092867407013426
    • Ganem NJ and Pellman D: Limiting the proliferation of polyploid cells. Cell 131: 437-440, 2007. (Pubitemid 350007703)
    • (2007) Cell , vol.131 , Issue.3 , pp. 437-440
    • Ganem, N.J.1    Pellman, D.2
  • 31
    • 49849083943 scopus 로고    scopus 로고
    • Whole chromosome instability and cancer: A complex relationship
    • Ricke RM, van Ree JH and van Deursen JM: Whole chromosome instability and cancer: A complex relationship. Trends Genet 24: 457-466, 2008.
    • (2008) Trends Genet , vol.24 , pp. 457-466
    • Ricke, R.M.1    Van Ree, J.H.2    Van Deursen, J.M.3
  • 32
    • 0032472915 scopus 로고    scopus 로고
    • AIM-1: A mammalian midbody-associated protein required for cytokinesis
    • DOI 10.1093/emboj/17.3.667
    • Terada Y, Tatsuka M, Suzuki F, Yasuda Y, Fujita S and Otsu M: AIM-1: a mammalian midbody-associated protein required for cytokinesis. EMBO J 17: 667-676, 1998. (Pubitemid 28062046)
    • (1998) EMBO Journal , vol.17 , Issue.3 , pp. 667-676
    • Terada, Y.1    Tatsuka, M.2    Suzuki, F.3    Yasuda, Y.4    Fujita, S.5    Otsu, M.6
  • 34
    • 33746931268 scopus 로고    scopus 로고
    • Polyploidization increases the sensitivity to DNA-damaging agents in mammalian cells
    • DOI 10.1016/j.febslet.2006.07.059, PII S0014579306009136
    • Hau PM, Siu WY, Wong N, Lai PB and Poon RY: Polyploidization increases the sensitivity to DNA-damaging agents in mammalian cells. FEBS Lett 580: 4727-4736, 2006. (Pubitemid 44189395)
    • (2006) FEBS Letters , vol.580 , Issue.19 , pp. 4727-4736
    • Hau, P.M.1    Siu, W.Y.2    Wong, N.3    Lai, P.B.S.4    Poon, R.Y.C.5
  • 35
    • 24744434639 scopus 로고    scopus 로고
    • Induction of polyploidy by histone deacetylase inhibitor: A pathway for antitumor effects
    • DOI 10.1158/0008-5472.CAN-04-4608
    • Xu WS, Perez G, Ngo L, Gui CY and Marks PA: Induction of polyploidy by histone deacetylase inhibitor: a pathway for anti-tumor effects. Cancer Res 65: 7832-7839, 2005. (Pubitemid 41297259)
    • (2005) Cancer Research , vol.65 , Issue.17 , pp. 7832-7839
    • Xu, W.-S.1    Perez, G.2    Ngo, L.3    Gui, C.-Y.4    Marks, P.A.5
  • 36
    • 0029680383 scopus 로고    scopus 로고
    • A brief staurosporine treatment of mitotic cells triggers premature exit from mitosis and polyploid cell formation
    • Hall LL, Th'ng JP, Guo XW, Teplitz RL and Bradbury EM: A brief staurosporine treatment of mitotic cells triggers premature exit from mitosis and polyploid cell formation. Cancer Res 56: 3551-3559, 1996.
    • (1996) Cancer Res , vol.56 , pp. 3551-3559
    • Hall, L.L.1    Th'ng, J.P.2    Guo, X.W.3    Teplitz, R.L.4    Bradbury, E.M.5
  • 37
    • 62549093591 scopus 로고    scopus 로고
    • The chemotherapeutic agents XK469 (2-{4-[(7-chloro-2-quinoxalinyl)oxy] phenoxy}propionic acid) and SH80 (2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy} propionic acid) inhibit cytokinesis and promote polyploidy and induce senescence
    • Reiners JJ Jr, Kleinman M, Joiakim A and Mathieu PA: The chemotherapeutic agents XK469 (2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid) and SH80 (2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid) inhibit cytokinesis and promote polyploidy and induce senescence. J Pharmacol Exp Ther 328: 796-806, 2009.
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 796-806
    • Reiners Jr., J.J.1    Kleinman, M.2    Joiakim, A.3    Mathieu, P.A.4
  • 38
    • 35548954250 scopus 로고    scopus 로고
    • The evolutionary consequences of polyploidy
    • Otto SP: The evolutionary consequences of polyploidy. Cell 131: 452-462, 2007.
    • (2007) Cell , vol.131 , pp. 452-462
    • Otto, S.P.1
  • 40
    • 57349153022 scopus 로고    scopus 로고
    • The resveratrol analogue 3,5,30,40,50-pentahydroxy-trans-stilbene inhibits cell transformation via MEK
    • Lee KW, Kang NJ, Rogozin EA, Oh S, Heo YS and Pugliese A: The resveratrol analogue 3,5,30,40,50-pentahydroxy-trans-stilbene inhibits cell transformation via MEK. Int J Cancer 123: 2487-2496, 2008.
    • (2008) Int J Cancer , vol.123 , pp. 2487-2496
    • Lee, K.W.1    Kang, N.J.2    Rogozin, E.A.3    Oh, S.4    Heo, Y.S.5    Pugliese, A.6
  • 41
    • 44149087812 scopus 로고    scopus 로고
    • Trans- and cis-stilbene polyphenols induced rapid perinuclear mitochondrial clustering and p53-independent apoptosis in cancer cells but not normal cells
    • Gosslau A, Pabbaraja S, Knapp S and Chen KY: Trans- and cis-stilbene polyphenols induced rapid perinuclear mitochondrial clustering and p53-independent apoptosis in cancer cells but not normal cells. Eur J Pharm 587: 25-34, 2008.
    • (2008) Eur J Pharm , vol.587 , pp. 25-34
    • Gosslau, A.1    Pabbaraja, S.2    Knapp, S.3    Chen, K.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.